Comparison ofin vitroandin vivobiological effects of trabectedin, lurbinectedin (PM01183) and Zalypsis® (PM00104)
Published 2013 View Full Article
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Title
Comparison ofin vitroandin vivobiological effects of trabectedin, lurbinectedin (PM01183) and Zalypsis® (PM00104)
Authors
Keywords
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Journal
INTERNATIONAL JOURNAL OF CANCER
Volume 133, Issue 9, Pages 2024-2033
Publisher
Wiley
Online
2013-04-16
DOI
10.1002/ijc.28213
References
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Related references
Note: Only part of the references are listed.- Role of Macrophage Targeting in the Antitumor Activity of Trabectedin
- (2013) Giovanni Germano et al. CANCER CELL
- First-in-man phase I trial of two schedules of the novel synthetic tetrahydroisoquinoline alkaloid PM00104 (Zalypsis) in patients with advanced solid tumours
- (2012) T A Yap et al. BRITISH JOURNAL OF CANCER
- Lurbinectedin (PM01183), a New DNA Minor Groove Binder, Inhibits Growth of Orthotopic Primary Graft of Cisplatin-Resistant Epithelial Ovarian Cancer
- (2012) A. Vidal et al. CLINICAL CANCER RESEARCH
- Phase I dose-escalating study of ES-285 given as a three-hour intravenous infusion every three weeks in patients with advanced malignant solid tumors
- (2012) C. Massard et al. INVESTIGATIONAL NEW DRUGS
- XPF-Dependent DNA Breaks and RNA Polymerase II Arrest Induced by Antitumor DNA Interstrand Crosslinking-Mimetic Alkaloids
- (2011) Sascha Feuerhahn et al. CHEMISTRY & BIOLOGY
- Characterization of a new trabectedin-resistant myxoid liposarcoma cell line that shows collateral sensitivity to methylating agents
- (2011) S. Uboldi et al. INTERNATIONAL JOURNAL OF CANCER
- Trabectedin and Its C Subunit Modified Analogue PM01183 Attenuate Nucleotide Excision Repair and Show Activity toward Platinum-Resistant Cells
- (2011) D. G. Soares et al. MOLECULAR CANCER THERAPEUTICS
- PM01183, a new DNA minor groove covalent binder with potent in vitro and in vivo anti-tumour activity
- (2010) JFM Leal et al. BRITISH JOURNAL OF PHARMACOLOGY
- Antitumor and Anti-inflammatory Effects of Trabectedin on Human Myxoid Liposarcoma Cells
- (2010) G. Germano et al. CANCER RESEARCH
- Trabectedin
- (2010) Natalie J. Carter et al. DRUGS
- 434 First-in-man phase I study of PM01183 using an accelerated titration design
- (2010) M.J. Ratain et al. EJC SUPPLEMENTS
- Trabectedin Plus Pegylated Liposomal Doxorubicin in Recurrent Ovarian Cancer
- (2010) Bradley J. Monk et al. JOURNAL OF CLINICAL ONCOLOGY
- Down-regulation of the Nucleotide Excision Repair gene XPG as a new mechanism of drug resistance in human and murine cancer cells
- (2010) Maria Antonietta Sabatino et al. Molecular Cancer
- Reduced Expression of the ROCK Inhibitor Rnd3 Is Associated with Increased Invasiveness and Metastatic Potential in Mesenchymal Tumor Cells
- (2010) Cristina Belgiovine et al. PLoS One
- Phase II randomized study of trabectedin given as two different every 3 weeks dose schedules (1.5 mg/m2 24 h or 1.3 mg/m2 3 h) to patients with relapsed, platinum-sensitive, advanced ovarian cancer
- (2009) J. M. Del Campo et al. ANNALS OF ONCOLOGY
- Molecular pharmacology and antitumor activity of Zalypsis ® in several human cancer cell lines
- (2009) Juan F.M. Leal et al. BIOCHEMICAL PHARMACOLOGY
- Zalypsis (PM00104) is a potent inducer of -H2AX foci and reveals the importance of the C ring of trabectedin for transcription-coupled repair inhibition
- (2009) J. Guirouilh-Barbat et al. MOLECULAR CANCER THERAPEUTICS
- Development of Yondelis® (trabectedin, ET-743). A semisynthetic process solves the supply problem
- (2009) Carmen Cuevas et al. NATURAL PRODUCT REPORTS
- Zalypsis: a novel marine-derived compound with potent antimyeloma activity that reveals high sensitivity of malignant plasma cells to DNA double-strand breaks
- (2008) E. M. Ocio et al. BLOOD
- Role of homologous recombination in trabectedin-induced DNA damage
- (2008) M. Tavecchio et al. EUROPEAN JOURNAL OF CANCER
- Transcription-coupled DNA Double-Strand Breaks Are Mediated via the Nucleotide Excision Repair and the Mre11-Rad50-Nbs1 Complex
- (2008) Josée Guirouilh-Barbat et al. MOLECULAR BIOLOGY OF THE CELL
- Relevance of the Fanconi anemia pathway in the response of human cells to trabectedin
- (2008) J. A. Casado et al. MOLECULAR CANCER THERAPEUTICS
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