Adrenomedullin is a therapeutic target in colorectal cancer

High-resolution genome-wide mapping of HIF-binding sites by ChIP-seq

(2011) J. Schodel et al.   BLOOD

VEGF is essential for hypoxia-inducible factor-mediated neovascularization but dispensable for endothelial sprouting

(2011) Sunday Oladipupo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Downregulation of c-MYC Protein Levels Contributes to Cancer Cell Survival under Dual Deficiency of Oxygen and Glucose

(2010) H. Okuyama et al.   CANCER RESEARCH

Vascular Endothelial Growth Factor and Epidermal Growth Factor Signaling Pathways as Therapeutic Targets for Colorectal Cancer

(2010) Thomas Winder et al.   GASTROENTEROLOGY

Oncogenic K-Ras Turns Death Receptors Into Metastasis-Promoting Receptors in Human and Mouse Colorectal Cancer Cells

(2010) Frederik J.H. Hoogwater et al.   GASTROENTEROLOGY

Oncogenic KRAS modulates mitochondrial metabolism in human colon cancer cells by inducing HIF-1a and HIF-2a target genes

(2010) Sang Y Chun et al.   Molecular Cancer

Hypoxia Activates the K-Ras Proto-Oncogene to Stimulate Angiogenesis and Inhibit Apoptosis in Colon Cancer Cells

(2010) Min Zeng et al.   PLoS One

Oncogenic KRAS and BRAF Differentially Regulate Hypoxia-Inducible Factor-1  and -2  in Colon Cancer

(2009) H. Kikuchi et al.   CANCER RESEARCH

Targeting adrenomedullin receptors with systemic delivery of neutralizing antibodies inhibits tumor angiogenesis and suppresses growth of human tumor xenografts in mice

(2009) Itidal Kaafarani et al.   FASEB JOURNAL

Epithelial to Mesenchymal Transition Is Impaired in Colon Cancer Cells With Microsatellite Instability

(2009) Maria S. Pino et al.   GASTROENTEROLOGY

An integrative genomics approach identifies Hypoxia Inducible Factor-1 (HIF-1)-target genes that form the core response to hypoxia

(2009) Yair Benita et al.   NUCLEIC ACIDS RESEARCH

Glucose Deprivation Contributes to the Development of KRAS Pathway Mutations in Tumor Cells

(2009) J. Yun et al.   SCIENCE

The role of hypoxia-inducible factors in tumorigenesis

(2008) E B Rankin et al.   CELL DEATH AND DIFFERENTIATION