Cervical cancer cell-derived interleukin-6 impairs CCR7-dependent migration of MMP-9-expressing dendritic cells

Chemotherapy Alters Monocyte Differentiation to Favor Generation of Cancer-Supporting M2 Macrophages in the Tumor Microenvironment

(2013) E. M. Dijkgraaf et al.   CANCER RESEARCH

A Phase I, Open-Label Study of Siltuximab, an Anti-IL-6 Monoclonal Antibody, in Patients with B-cell Non-Hodgkin Lymphoma, Multiple Myeloma, or Castleman Disease

(2013) R. Kurzrock et al.   CLINICAL CANCER RESEARCH

The Human papillomavirus type 16 E7 oncoprotein induces a transcriptional repressor complex on the Toll-like receptor 9 promoter

(2013) Uzma A. Hasan et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Epithelial Cell Responses to Infection with Human Papillomavirus

(2012) M. A. Stanley   CLINICAL MICROBIOLOGY REVIEWS

Targeting the Interleukin-6/Jak/Stat Pathway in Human Malignancies

(2012) Pasquale Sansone et al.   JOURNAL OF CLINICAL ONCOLOGY

Transcriptional Repression of E-Cadherin by Human Papillomavirus Type 16 E6

(2012) Zarina J. D'Costa et al.   PLoS One

Therapy of Human Papillomavirus-Related Disease

(2012) Peter L. Stern et al.   VACCINE

Human Papillomavirus Type 8 Interferes with a Novel C/EBPβ-Mediated Mechanism of Keratinocyte CCL20 Chemokine Expression and Langerhans Cell Migration

(2012) Tanya Sperling et al.   PLoS Pathogens

Molecular Pathobiology of Human Cervical High-Grade Lesions: Paracrine STAT3 Activation in Tumor-Instructed Myeloid Cells Drives Local MMP-9 Expression

(2011) N. Schroer et al.   CANCER RESEARCH

Interleukin-6 as a Therapeutic Target in Human Ovarian Cancer

(2011) Jermaine Coward et al.   CLINICAL CANCER RESEARCH

Randomised phase II study of siltuximab (CNTO 328), an anti-IL-6 monoclonal antibody, in combination with mitoxantrone/prednisone versus mitoxantrone/prednisone alone in metastatic castration-resistant prostate cancer

(2011) K. Fizazi et al.   EUROPEAN JOURNAL OF CANCER

M2 Macrophages Induced by Prostaglandin E2 and IL-6 from Cervical Carcinoma Are Switched to Activated M1 Macrophages by CD4+ Th1 Cells

(2011) M. Heusinkveld et al.   JOURNAL OF IMMUNOLOGY

Pharmacokinetic and Pharmacodynamic Modeling of an Anti-Interleukin-6 Chimeric Monoclonal Antibody (Siltuximab) in Patients with Metastatic Renal Cell Carcinoma

(2010) T. Puchalski et al.   CLINICAL CANCER RESEARCH

Human Papillomavirus 16-Associated Cervical Intraepithelial Neoplasia in Humans Excludes CD8 T Cells from Dysplastic Epithelium

(2010) C. L. Trimble et al.   JOURNAL OF IMMUNOLOGY

Differential Regulation of Human Papillomavirus Type 8 by Interferon Regulatory Factors 3 and 7

(2010) M. Oldak et al.   JOURNAL OF VIROLOGY

HPV-16 E5 down-regulates expression of surface HLA class I and reduces recognition by CD8 T cells

(2010) M.S. Campo et al.   VIROLOGY

Clinician's guide to human papillomavirus immunology: knowns and unknowns

(2009) Mark H Einstein et al.   LANCET INFECTIOUS DISEASES

A review of human carcinogens—Part B: biological agents

(2009) Véronique Bouvard et al.   LANCET ONCOLOGY

Tumor-mediated liver X receptor-α activation inhibits CC chemokine receptor-7 expression on dendritic cells and dampens antitumor responses

(2009) Eduardo J Villablanca et al.   NATURE MEDICINE

Turning NF-κB and IRFs on and off in DC

(2008) Tsuneyasu Kaisho et al.   TRENDS IN IMMUNOLOGY

The wolf in sheep's clothing: the role of interleukin-6 in immunity, inflammation and cancer

(2008) Willscott E. Naugler et al.   TRENDS IN MOLECULAR MEDICINE

Interaction between inflammation and angiogenesis during different stages of cervical carcinogenesis

(2007) Jasenka Mazibrada et al.   GYNECOLOGIC ONCOLOGY