Humanized tumor mice-A new model to study and manipulate the immune response in advanced cancer therapy

The Innate NK Cells, Allograft Rejection, and a Key Role for IL-15

(2014) A. Kroemer et al.   JOURNAL OF IMMUNOLOGY

Monoclonal Antibodies in Clinical Oncology

(2012) S. Dalle et al.   Anti-Cancer Agents in Medicinal Chemistry

In vivo assay of human NK-dependent ADCC using NOD/SCID/γcnull (NOG) mice

(2010) Miho Shiokawa et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Human NK cells of mice with reconstituted human immune system components require preactivation to acquire functional competence

(2010) T. Strowig et al.   BLOOD

A complement-dependent cytotoxicity-enhancing anti-CD20 antibody mediating potent antitumor activity in the humanized NOD/Shi-scid, IL-2Rγnull mouse lymphoma model

(2010) Fumihiko Sato et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Intrahepatically transplanted human cord blood cells reduce SW480 tumor growth in the presence of bispecific EpCAM/CD3 antibody

(2010) Annika Wulf-Goldenberg et al.   CYTOTHERAPY

Establishment of a rhabdomyosarcoma xenograft model in human-adapted mice

(2010) Seitz   ONCOLOGY REPORTS

Generation of functional human T-cell subsets with HLA-restricted immune responses in HLA class I expressing NOD/SCID/IL2r null humanized mice

(2010) L. D. Shultz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Breast tumor cells isolated from in vitro resistance to trastuzumab remain sensitive to trastuzumab anti-tumor effects in vivo and to ADCC killing

(2009) Timothy E. Kute et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Defucosylated Anti-CCR4 Monoclonal Antibody Exerts Potent ADCC against Primary ATLL Cells Mediated by Autologous Human Immune Cells in NOD/Shi-scid, IL-2R null Mice In Vivo

(2009) A. Ito et al.   JOURNAL OF IMMUNOLOGY

Suppression of Human Immunodeficiency Virus Type 1 (HIV-1) Viremia with Reverse Transcriptase and Integrase Inhibitors, CD4+ T-Cell Recovery, and Viral Rebound upon Interruption of Therapy in a New Model for HIV Treatment in the Humanized Rag2-/- c-/- Mouse

(2009) S. K. Choudhary et al.   JOURNAL OF VIROLOGY

Defucosylated anti-CCR4 monoclonal antibody exercises potent ADCC-mediated antitumor effect in the novel tumor-bearing humanized NOD/Shi-scid, IL-2Rγnull mouse model

(2008) Asahi Ito et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

IL-15 trans-presentation promotes human NK cell development and differentiation in vivo

(2008) Nicholas D. Huntington et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Cancer Immunology

(2008) Olivera J. Finn   NEW ENGLAND JOURNAL OF MEDICINE

Antiretroviral Pre-exposure Prophylaxis Prevents Vaginal Transmission of HIV-1 in Humanized BLT Mice

(2008) Paul W Denton et al.   PLOS MEDICINE