Article
Nutrition & Dietetics
Jinyu Man, Yingchun Ni, Xiaorong Yang, Tongchao Zhang, Ziyu Yuan, Hui Chen, Xingdong Chen, Ming Lu, Weimin Ye
Summary: A good lifestyle is associated with a reduced risk of gastric cancer regardless of family history, while family history of early-onset cancer is closely related to the occurrence of gastric cancer. About 34% of gastric cancer cases can be attributed to non-compliance with three or more healthy lifestyle factors.
FRONTIERS IN NUTRITION
(2021)
Article
Oncology
Nuha El Sharif, Imtithal Khatib
Summary: The study found that factors such as late menarche, long-term use of oral contraceptives, hormone contraceptives, hormone replacement therapy, nulliparity, parental consanguinity marriage, and positive family history were all significantly associated with increased risk of breast cancer among women in the West Bank of Palestine. This highlights the importance of rationalizing the use of reproductive hormones, both for birth control and therapeutic purposes, particularly in this region.
CANCER EPIDEMIOLOGY
(2021)
Article
Oncology
Manushak Avagyan, Anahit Demirchyan, Lusine Abrahamyan
Summary: This study aimed to identify possible risk factors for childhood cancer in Armenia. The findings showed that maternal usage of folic acid during pregnancy was protective against childhood cancer, while experiencing horrifying events during pregnancy and having induced abortions before getting pregnant were associated with higher odds for a child to develop cancer.
Article
Multidisciplinary Sciences
Mwiza Gideon Singini, Freddy Sitas, Debbie Bradshaw, Wenlong Carl Chen, Melitah Motlhale, Abram Bunya Kamiza, Chantal Babb de Villiers, Cathryn M. Lewis, Christopher G. Mathew, Tim Waterboer, Robert Newton, Mazvita Muchengeti, Elvira Singh
Summary: In black South African women, the risks factors for cervical cancer were ranked in order of priority as being HIV positive, having lower educational attainment, higher parity, using hormonal contraceptives, heavy alcohol consumption, current smoking, and living in rural areas.
Article
Oncology
Stella Koutros, Kathy L. Decker, Dalsu Baris, Larissa A. Pardo, Alison Johnson, G. M. Monawar Hosain, Nathaniel Rothman, Margaret R. Karagas, Molly R. Schwenn, Debra T. Silverman
Summary: Twin studies suggest a familial aggregation of bladder cancer, with individuals having a first-degree relative with bladder cancer having nearly double the risk of developing bladder cancer. Additionally, a family history of female genital cancer, melanoma, and tobacco-associated cancer also increased the risk of bladder cancer.
INTERNATIONAL JOURNAL OF CANCER
(2021)
Article
Medicine, General & Internal
Rui Zhang, He Li, Ni Li, Ju-Fang Shi, Jiang Li, Hong-Da Chen, Yi-Wen Yu, Chao Qin, Jian-Song Ren, Wan-Qing Chen, Jie He
Summary: This study identified smoking, alcohol consumption, history of stomach disease, and family history of first-degree relatives with gastric cancer as high-risk factors for gastric cancer. Therefore, attention should be paid to screening these populations for gastric cancer.
CHINESE MEDICAL JOURNAL
(2021)
Article
Medicine, General & Internal
Lili Meng, Sara Oberg, Anna Sandstrom, Chen Wang, Marie Reilly
Summary: This study compares the association of predictive factors with incident cervical insufficiency (ICI) in nulliparous and parous women, and further investigates various aspects of obstetric history for multiparous women. The study finds that multifetal gestation and previous miscarriages are important risk factors for ICI in nulliparous women, while a history of preterm delivery is an independent predictor for parous women. Previous prolonged labor or delivery of a large infant are inversely associated with the risk of ICI in the current pregnancy.
Article
Public, Environmental & Occupational Health
Bingbing Xiang, Shulan Jiao, Yongyu Si, Yuting Yao, Feng Yuan, Rui Chen
Summary: Postoperative pneumonia is a serious complication that can lead to adverse outcomes. Our study identified six independent risk factors that can be used for risk stratification and management of postoperative pneumonia. Gram-negative pathogens are the most common causative agents, and multidrug resistant bacteria are prevalent.
FRONTIERS IN PUBLIC HEALTH
(2022)
Article
Multidisciplinary Sciences
Heng-Jui Chang, Yuan-Hung Pong, Chen-Yen Chiang, Po-Chien Huang, Ming-Hua Wang, Yu-Jiun Chan, Tzuo-Yun Lan
Summary: The rising incidence rate of prostate cancer (PCa) worldwide is a concern. The association between human papillomavirus (HPV) and PCa has been widely investigated. This case-control study in Taiwan found a slightly significant association between HPV infection and PCa, but the focus should be on other risk factors such as dietary habits, personal lifestyle, and family history.
SCIENTIFIC REPORTS
(2023)
Article
Oncology
Issa Ghrouz, Nuha El Sharif
Summary: A matched hospital-based case-control study in Palestine indicated that factors such as consuming more fruits/vegetables, taking aspirin, and having multiple birth siblings lowered the risk of CRC, while consuming grilled red meat, smoking, parental consanguinity, and family history of cancer increased the likelihood of CRC. These results confirmed the association between CRC and red meat intake and smoking, and identified additional risk factors like parental consanguinity and family history of cancer.
NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL
(2021)
Article
Health Care Sciences & Services
Yoon Suk Jung, Huiyeon Song, Mai Thi Xuan Tran, Boyoung Park, Chang Mo Moon
Summary: Large-scale studies on the association between family history and colorectal cancer (CRC) risk in Asians are lacking. We conducted a study in the Korean population and found that individuals with a family history of CRC, especially in younger age groups, had a higher risk of developing CRC compared to those without a family history.
JOURNAL OF PERSONALIZED MEDICINE
(2022)
Article
Medicine, General & Internal
Yadi Zheng, Xuesi Dong, Jiang Li, Chao Qin, Yongjie Xu, Fei Wang, Wei Cao, Changfa Xia, Yiwen Yu, Liang Zhao, Zheng Wu, Zilin Luo, Wanqing Chen, Ni Li, Jie He
Summary: This study identifies the risk-adapted starting age of breast cancer screening in China based on comprehensive consideration of breast cancer risk factors, and develops an online calculator to calculate the optimal starting age of screening for individuals.
Article
Environmental Sciences
Samira Negrichi, Salima Taleb
Summary: Colorectal carcinoma (CRC) is the second most common cancer diagnosed in Algeria, with an increasing incidence and mortality rate. Factors such as high education level, family history of cancer, occupational exposures, obesity, alcohol consumption, and dietary factors were found to be associated with CRC risk in this study. Public health campaigns to raise awareness about CRC and promote healthy dietary choices may help in prevention.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2021)
Article
Infectious Diseases
Masato Inaba, Yukiko Miyake, Kazutaka Yasuda
Summary: This study identified factors that influence the secondary household transmission of SARS-CoV-2 from positive cohabitants. The findings suggest that recent SARS-CoV-2 infection, home isolation of positive cohabitants, and older age of primary index cases are associated with a reduced risk of secondary household transmission. Further research is needed to determine the effectiveness of booster vaccinations.
INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES
(2023)
Article
Environmental Sciences
Xuejun Li, Fengju Song, Xiaotu Liu, Anqi Shan, Yubei Huang, Zhengjun Yang, Haixin Li, Qiaoyun Yang, Yue Yu, Hong Zheng, Xu-Chen Cao, Da Chen, Ke-Xin Chen, Xi Chen, Nai-Jun Tang
Summary: This study found an association between PFAS and breast cancer in Chinese women, with PFOA being associated with the occurrence of hormone receptor-positive breast cancer.
ENVIRONMENTAL HEALTH
(2022)
Article
Oncology
Luca Giraldi, Jovana Stojanovic, Dario Arzani, Roberto Persiani, Jinfu Hu, Kenneth C. Johnson, Zuo-Feng Zhang, Monica Ferraroni, Domenico Palli, Guo-Pei Yu, Carlo La Vecchia, Claudio Pelucchi, Nuno Lunet, Ana Ferro, Reza Malekzadeh, Joshua Muscat, David Zaridze, Dmitry Maximovich, Nuria Aragones, Vicente Martin, Jesus Vioque, Eva M. Navarrete-Munoz, Mohammadreza Pakseresht, Eva Negri, Matteo Rota, Farhad Pourfarzi, Lina Mu, Robert C. Kurtz, Areti Lagiou, Pagona Lagiou, Roberta Pastorino, Stefania Boccia
Summary: This study aimed to examine the association between height and risk of gastric cancer. Through a large pooled analysis of case-control studies, the study found no significant association between adult height and gastric cancer.
EUROPEAN JOURNAL OF CANCER PREVENTION
(2023)
Article
Nutrition & Dietetics
Federica Turati, Marta Rossi, Panagiota Strikoudi, Monica Ferraroni, Maria Parpinel, Diego Serraino, Eva Negri, Carlo La Vecchia
Summary: This study found a positive association between dietary intake of branched-chain amino acids (BCAA) and pancreatic cancer risk. The association persisted even after excluding subjects with diabetes and family history of pancreatic cancer. These findings support previous research on the link between circulating BCAA and pancreatic cancer.
BRITISH JOURNAL OF NUTRITION
(2023)
Article
Dentistry, Oral Surgery & Medicine
Neerav Goyal, Max Hennessy, Erik Lehman, Wenxue Lin, Antonio Agudo, Wolfgang Ahrens, Stefania Boccia, Paul Brennan, Hermann Brenner, Gabriella Cadoni, Cristina Canova, Chu Chen, David Conway, Maria Paula Curado, Luigino Dal Maso, Alexander W. Daudt, Valeria Edefonti, Eleonora Fabianova, Leticia Fernandez, Silvia Franceschi, Werner Garavello, Maura Gillison, Richard B. Hayes, Claire Healy, Rolando Herrero, Ivana Holcatova, Jossy L. Kanda, Karl Kelsey, Bo T. Hansen, Rosalina Koifman, Pagona Lagiou, Carlo La Vecchia, Fabio Levi, Guojun Li, Jolanta Lissowska, Rossana Mendoza Lopez, Daniele Luce, Gary Macfarlane, Dana Mates, Keitaro Matsuo, Michael McClean, Ana Menezes, Gwenn Menvielle, Hal Morgenstern, Kirsten Moysich, Eva Negri, Andrew F. Olshan, Tamas Pandics, Jerry Polesel, Mark Purdue, Loredana Radoi, Heribert Ramroth, Lorenzo Richiardi, Stimson Schantz, Stephen M. Schwartz, Diego Serraino, Oxana Shangina, Elaine Smith, Erich M. Sturgis, Beata Swiatkowska, Peter Thomson, Thomas L. Vaughan, Marta Vilensky, Deborah M. Winn, Victor Wunsch-Filho, Guo-Pei Yu, Jose P. Zevallos, Zuo-Feng Zhang, Tongzhang Zheng, Ariana Znaor, Paolo Boffetta, Mia Hashibe, Yuan-Chin A. Lee, Joshua E. Muscat
Summary: This study analyzed the relationship between cigarette smoking, alcohol consumption, and head and neck cancer risk factors in less developed and more developed countries. The results showed that the duration of smoking and alcohol consumption had different effects on the risk of specific cancer sites depending on the country's level of development. These findings suggest that the degree of industrialization and economic development affects the relationship between smoking, alcohol, and head and neck cancer.
Article
Oncology
Giulia Collatuzzo, Carlo La Vecchia, Fabio Parazzini, Gianfranco Alicandro, Federica Turati, Matteo Di Maso, Matteo Malvezzi, Claudio Pelucchi, Eva Negri, Paolo Boffetta
Summary: This study provides a comprehensive assessment of infection-related cancers burden in Italy. It shows that 7.6% of cancer deaths and 6.9% of incident cases are attributable to infections, with higher proportions in men than women. Helicobacter pylori is the leading cause of infection-related cancer deaths, followed by hepatitis C virus, human immunodeficiency virus, and hepatitis B virus.
EUROPEAN JOURNAL OF CANCER
(2023)
Article
Oncology
Margherita Pizzato, Giulia Collatuzzo, Claudia Santucci, Matteo Malvezzi, Paolo Boffetta, Alessandro Comandone, Fabio Levi, Carlo La Vecchia, Paola Bertuccio, Eva Negri
Summary: This study provides mortality trends for soft-tissue sarcomas (STSs) in selected countries worldwide over the last 2 decades, along with predicted figures for 2025. The results show an increase in the number of deaths and mortality rates in most countries for both sexes. In 2025, the number of STS deaths is predicted to continue increasing in most countries and both sexes.
EUROPEAN JOURNAL OF CANCER PREVENTION
(2023)
Article
Nutrition & Dietetics
Federica Turati, Federica Concina, Paola Bertuccio, Federica Fiori, Maria Parpinel, Martina Taborelli, Valentina Rosato, Werner Garavello, Eva Negri, Carlo La Vecchia
Summary: This study aimed to evaluate the association between the intake of specific fibers with prebiotic activity and laryngeal cancer risk. The results showed that the intake of kestose, raffinose, and stachyose was inversely associated with laryngeal cancer risk, while ITFs, nystose, and 1F-beta-fructofuranosylnystose were not associated with the risk. Current smokers and heavy drinkers with low intake of prebiotic fibers had a significantly higher risk of laryngeal cancer compared to never smokers and moderate drinkers with high intake of prebiotic fibers.
EUROPEAN JOURNAL OF NUTRITION
(2023)
Article
Medicine, Legal
Sofia Pavanello, Angelo Moretto, Carlo La Vecchia, Gianfranco Alicandro
Summary: Many studies have been conducted on the relationship between non-sugar sweeteners (NSS) and cancer in the past five decades, but the issue still remains of interest. In this comprehensive review, both toxicological and epidemiological evidence on the possible link between NSS consumption and cancer risk were quantitatively evaluated. The majority of studies showed no associations between NSS consumption and cancer, and the risks found in a few studies were not confirmed by others. Based on the review of both experimental and epidemiological data, it can be concluded that there is no evidence of cancer risk associated with NSS consumption.
REGULATORY TOXICOLOGY AND PHARMACOLOGY
(2023)
Article
Multidisciplinary Sciences
Marco Mariani, Roberta Pastorino, Denise Pires Marafon, Ken C. Johnson, Jinfu Hu, Antonio Jose Molina de la Torre, Guillermo Fernandez-Tardon, David Zaridze, Dmitry Maximovich, Eva Negri, Carlo La Vecchia, Zuo-Feng Zhang, Robert C. Kurtz, Claudio Pelucchi, Matteo Rota, Stefania Boccia
Summary: This study aimed to estimate the association between leisure-time physical activity (PA) and gastric cancer (GC) through a pooled analysis of case-control studies. The results showed no significant relationship between leisure-time PA and GC, except for a slight decreased risk below age 55 and in control population-based studies.
Article
Oncology
Mark Lawler, Lynne Davis, Simon Oberst, Kathy Oliver, Alexander Eggermont, Anna Schmutz, Carlo La Vecchia, Claudia Allemani, Yolande Lievens, Peter Naredi, Tanja Cufer, Ajay Aggarwal, Matti Aapro, Kathi Apostolidis, Anne-Marie Baird, Fatima Cardoso, Andreas Charalambous, Michel P. Coleman, Alberto Costa, Mirjam Crul, Csaba L. Degi, Federica Di Nicolantonio, Sema Erdem, Marius Geanta, Jan Geissler, Jacek Jassem, Beata Jagielska, Bengt Jonsson, Daniel Kelly, Olaf Kelm, Teodora Kolarova, Tezer Kutluk, Grant Lewison, Francoise Meunier, Jana Pelouchova, Thierry Philip, Richard Price, Beate Rau, Isabel T. Rubio, Peter Selby, Maja Juznic Sotlar, Gilliosa Spurrier-Bernard, Jolanda C. van Hoeve, Eduard Vrdoljak, Willien Westerhuis, Urszula Wojciechowska, Richard Sullivan
Summary: Cancer research is vital for improving cancer care, and patients treated in research-active hospitals have better outcomes. However, the COVID-19 pandemic has negatively impacted cancer outcomes in Europe and set back progress by almost a decade. The Lancet Oncology European Groundshot Commission aims to use detailed data on cancer research to inform future cancer care strategies in Europe.
Article
Health Care Sciences & Services
Andrea Piccinini, Paolo Bailo, Giussy Barbara, Monica Miozzo, Silvia Tabano, Patrizia Colapietro, Claudia Fare, Silvia Maria Sirchia, Elena Battaglioli, Paola Bertuccio, Giulia Manenti, Laila Micci, Carlo La Vecchia, Alessandra Kustermann, Simona Gaudi
Summary: Violence against women has negative consequences on their health. The EpiWE project aims to investigate the epigenetic signatures associated with intimate partner and sexual violence-induced stress-related disorders. The study found abnormal methylation levels of brain-derived neurotrophic factor, dopamine receptor D2, and insulin-like growth factor 2 genes in victims, indicating potential molecular pathways for addressing the long-term effects of violence and implementing precision medicine protocols.
Article
Oncology
Claudia Santucci, Silvia Mignozzi, Matteo Malvezzi, Giulia Collatuzzo, Fabio Levi, Carlo La Vecchia, Eva Negri
Summary: This study provides a global overview of esophageal cancer mortality, analyzing trends over the past three decades and predicting mortality rates for 2025. The results show that male esophageal cancer mortality is generally decreasing, while female mortality rates are either slightly increasing or showing favorable trends. Squamous cell carcinoma remains the most common histotype, but there is an upward trend in the incidence of adenocarcinoma in some high-income countries.
CANCER EPIDEMIOLOGY
(2023)
Article
Oncology
Matteo Di Maso, Claudio Pelucchi, Giulia Collatuzzo, Gianfranco Alicandro, Matteo Malvezzi, Fabio Parazzini, Eva Negri, Paolo Boffetta, Carlo La Vecchia, Federica Turati
Summary: The burden of cancer associated with overweight and obesity in Italy is considerable, with 3.6% of cancers in men and 4.0% in women attributable to overweight and obesity. The most affected cancer types in both sexes include esophageal adenocarcinoma, liver cancer, kidney cancer, pancreatic cancer, colorectal cancer, endometrial cancer, and post-menopausal breast cancer.
CANCER EPIDEMIOLOGY
(2023)
