Article
Thermodynamics
Anjanay Pandey, A. S. K. Sinha, Krishna Raghav Chaturvedi, Tushar Sharma
Summary: This study quantified the impact of subsurface conditions on CO2 foam, finding that increasing salt concentration significantly affects foam stability and CO2 molality. Additionally, increasing surfactant amount had negligible impact on CO2 molality. The CO2 foam exhibited non-Newtonian shear thinning behavior and showed potential for enhanced oil recovery and carbon storage in subsurface environment.
Review
Microbiology
Praveen Rahi, Estelle Muhle, Cyril Scandola, Gerald Touak, Dominique Clermont
Summary: This study utilized a polyphasic taxonomy approach to accurately classify six strains within the Enterobacter cloacae complex (ECC). The 16S rRNA gene-based phylogeny failed to group all ECC species into a monophyletic cluster, while genome sequence-based phylogenetic approaches successfully grouped all species. A new species named Enterobacter pasteurii sp. nov. was proposed based on comprehensive genotypic and phenotypic characterizations.
MICROBIOLOGY SPECTRUM
(2023)
Article
Multidisciplinary Sciences
Sekar Harikrishnan, Shanmugam Sudarshan, Kandasamy Sivasubramani, M. S. Nandini, Jayaraman Narenkumar, Vasudevan Ramachandran, Bader O. Almutairi, Paulraj Arunkumar, Aruliah Rajasekar, Singaram Jayalakshmi
Summary: The widespread use of synthetic pesticides has led to various issues, necessitating the development of new microbial derived insecticides for safe and environmentally-friendly pest control. This study evaluated the toxicity of a biosurfactant produced from Enterobacter cloacae on mosquito larvae and termites, finding that it exhibited larvicidal and anti-termite activity. The biosurfactant caused substantial tissue damage in the studied organisms. These findings suggest that the microbial biosurfactant has great potential for the control of mosquitoes and termites.
SCIENTIFIC REPORTS
(2023)
Review
Biochemistry & Molecular Biology
Zhiping Fan, Ping Cheng, Pan Zhang, Guangming Zhang, Jun Han
Summary: The exceptional network assembly of natural polysaccharides/proteins-based hydrogels offers favorable biological characteristics and tunable physical properties making them ideal candidates for food and biomedical applications. Rheological analysis provides quantitative insights into the assembled network, crucial for determining hydrogel properties and their suitability for food or biomedical use.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2022)
Article
Polymer Science
Zhiping Fan, Ping Cheng, Lixia Chu, Jun Han
Summary: Natural polysaccharide-based hydrogels have excellent biocompatibility and soft physical properties, making them promising candidates for food and biomedical applications. In this study, a new gel system composed of pectin and salecan was designed and prepared. Structural and rheological analysis revealed the potential advantages of these pectin-salecan hydrogels in various food and biomedical fields.
Article
Food Science & Technology
Min Huang, Alicia Hui Ping Theng, Dongying Yang, Hongshun Yang
Summary: This study found that varying concentrations of kappa-carrageenan affect the rheological properties of a model cake flour system, leading to increased firmness, higher resistance towards deformation, and delayed starch gelatinisation. The results highlight the potential application of carrageenan-containing materials in bakery products.
LWT-FOOD SCIENCE AND TECHNOLOGY
(2021)
Article
Environmental Sciences
Mu Su, Feiyu Han, Mengxiao Wang, Jingxuan Ma, Xuewei Wang, Zhijun Wang, Shuijin Hu, Zhen Li
Summary: The study revealed that high CEC montmorillonite clay minerals can adsorb more bacterial cells, thus providing a certain level of protection for microorganisms against Pb2+ stress. However, the addition of Enterobacter sp. actually increased the residual Pb2+ concentration in the solution by 7.5%, indicating that the adsorption of typical soil bacterium on clay minerals has a certain impact on the adsorption of Pb.
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
(2021)
Review
Biotechnology & Applied Microbiology
S. Saeidy, B. Petera, G. Pierre, T. A. Fenoradosoa, Djomdi Djomdi, P. Michaud, C. Delattre
Summary: The chemical structure, extraction processes, techno-functional and biological properties of Arabinogalactans (AGs) are discussed in this review, focusing on non-traditional plant sources. It highlights the health benefits and immunomodulatory effects of AGs in in-vivo model systems.
BIOTECHNOLOGY ADVANCES
(2021)
Article
Chemistry, Applied
Said Elmarhoum, Komla Ako
Summary: The widespread application of polysaccharides is limited by low syneresis impact. Our study demonstrated that the thermodynamic instability of kappa-carrageenan polysaccharide is the origin of syneresis and investigated the effects of KCl salt on critical concentration and LCCT. The difference between Tg and LCCT serves as the thermomotive force behind the syneresis of many colloidal gels.
CARBOHYDRATE POLYMERS
(2021)
Article
Chemistry, Applied
Akshay Bisht, Kelvin K. T. Goh, Ian M. Sims, Patrick J. B. Edwards, Lara Matia-Merino
Summary: Mamaku polysaccharide (MP) is a water-soluble shear-thickening biopolymer that has shown potential to be used in the design of novel food products targeting satiety management and weight loss. However, high temperature and shear treatment can affect its rheological behavior, leading to changes in molecular structure and rheological properties.
FOOD HYDROCOLLOIDS
(2023)
Review
Biochemistry & Molecular Biology
Emmanuel M. Nsengiyumva, Paschalis Alexandridis
Summary: Xanthan gum is a naturally occurring polysaccharide with various applications, such as in food, pharmaceutical, cosmetic, and petroleum extraction industries. This review provides fundamental information on the behavior of xanthan gum in aqueous media and highlights its responses to different stimuli.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2022)
Review
Biochemistry & Molecular Biology
Yige Song, Shuxin Li, Hao Gong, Ryan Chak Sang Yip, Hao Chen
Summary: The biological characteristics of microbial polysaccharides make them an excellent choice for bio-pharmaceuticals by resolving application issues associated with plant and animal polysaccharides and being recognized as eco-friendly alternatives. This review highlights the microstructure and properties of microbial polysaccharides, emphasizing their potential medical applications in human disease treatment, anti-aging, and drug delivery from a pathogenic perspective. The scholarly developments and commercial applications of microbial polysaccharides as medical raw materials are also discussed. Understanding the use of microbial polysaccharides in biopharmaceuticals is essential for the future development of pharmacology and therapeutic medicine.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Chemistry, Applied
Shayane da Silva Milhorini, Fernanda Fogagnoli Simas, Fhernanda Ribeiro Smiderle, Liana Inara de Jesus, Fabio Rogerio Rosado, Eduardo Luis Longoria, Marcello Iacomini
Summary: This study focused on extracting polysaccharides from the fruiting bodies of the giant M. titans mushroom and evaluated their physicochemical properties. It was found that the extracted beta-glucans from M. titans could form gel under suitable conditions, showing potential industrial application as thickening or gelling agents.
FOOD HYDROCOLLOIDS
(2022)
Article
Biochemistry & Molecular Biology
Khaled Arab, Babak Ghanbarzadeh, Shafagh Karimi, Behzad Ebrahimi, Mohammadyar Hosseini
Summary: A new polysaccharide was isolated from Ocimum album L. seed, which had an acidic heteropolysaccharide structure and a molecular weight of 1935 kDa. The polysaccharide solution exhibited shear-thinning behavior and pseudoplastic properties. It also had gel-like behavior at concentrations higher than 0.1% and showed thermally irreversible gels at 1% concentration.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Biotechnology & Applied Microbiology
Zhimeng Su, Shitong Zhang, Weiqing Zhang, Ziqi Guo, Fuchun Li, Xuelin Li
Summary: The biofilm contributes to the carbonate mineralization process and its destruction inhibits carbonate formation. The formation of carbonate minerals is delayed and reduced in mass when the biofilm is disrupted. Additionally, a unique form of concave spherical calcite is only found around the biofilm.
INTERNATIONAL BIODETERIORATION & BIODEGRADATION
(2023)
Article
Biochemistry & Molecular Biology
Patricia Concordio-Reis, Sonia S. Ferreira, Vitor D. Alves, Xavier Moppert, Jean Guezennec, Manuel A. Coimbra, Maria A. M. Reis, Filomena Freitas
Summary: This study investigated the chemical composition and rheological properties of a novel exopolysaccharide (EPS), which showed that it had the ability to increase viscosity with concentration, exhibited non-Newtonian shear thinning behavior at concentrations above 0.1 wt%, and demonstrated weak gel-like structure and thermal stability. It also showed good recoverability and self-healing properties.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Biochemistry & Molecular Biology
Marijana Ponjavic, Ivana Malagurski, Jelena Lazic, Sanja Jeremic, Vladimir Pavlovic, Nevena Prlainovic, Vesna Maksimovic, Vladan Cosovic, Leonard Ionut Atanase, Filomena Freitas, Mariana Matos, Jasmina Nikodinovic-Runic
Summary: Researchers combined polyhydroxyalkanoates (PHAs) with a bacterial pigment, prodigiosin (PG), to create functionally enhanced poly(3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV)-based biomaterials. The addition of PG improved the physical properties and functionality of the biomaterials. The films with PG had a more organized internal structure, higher melting and degradation temperatures, and exhibited excellent anticancer activity against colon cancer cells.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Review
Biochemistry & Molecular Biology
Bruno Serafim, Ana R. Bernardino, Filomena Freitas, Cristiana A. V. Torres
Summary: This article reviews the recent research on phenazines produced by pseudomonads. The biosynthetic pathways, regulatory mechanisms, production processes, bioactivities, and applications of these compounds are thoroughly discussed in this manuscript.
Article
Polymer Science
Diana Araujo, Thomas Rodrigues, Catarina Roma-Rodrigues, Vitor D. Alves, Alexandra R. R. Fernandes, Filomena Freitas
Summary: Chitin-glucan complex hydrogels were prepared from aqueous alkaline solutions and studied for their morphology, swelling behavior, mechanical properties, drug loading/release ability, and permeation through artificial membranes. The hydrogels displayed a highly porous microstructure and had a spontaneous and immediate swelling in aqueous media. In addition, they showed no significant effects on cell viability, migration ability, and morphology. These hydrogels have potential as novel transdermal drug delivery platforms.
Article
Biotechnology & Applied Microbiology
Patricia Concordio-Reis, Ana Catarina Macedo, Martim Cardeira, Xavier Moppert, Jean Guezennec, Chantal Sevrin, Christian Grandfils, Ana Teresa Serra, Filomena Freitas
Summary: In this study, a novel exopolysaccharide (EPS) derived from Alteromonas macleodii Mo 169 was used to prepare selenium nanoparticles (SeNPs). The synthesized nanoparticles exhibited good dispersion and spherical shape, with an average size of 32 nm. The cytotoxicity of the EPS and EPS/SeNPs bio-nanocomposite was evaluated on human keratinocyte and fibroblast cell lines, showing no significant cytotoxicity for EPS alone and only mild cytotoxicity for the bio-nanocomposite at higher concentrations. Moreover, the non-cytotoxic concentrations of EPS/SeNPs bio-nanocomposite demonstrated a significant cellular antioxidant effect on the tested cell line, reducing ROS levels by up to 33.8%.
BIOENGINEERING-BASEL
(2023)
Article
Biophysics
Silvia Baptista, Joao R. Pereira, Bruno M. Guerreiro, Filipa Baptista, Jorge C. Silva, Filomena Freitas
Summary: This study evaluated a O/W cosmetic formulation containing FucoPol, a fucose-containing bacterial polysaccharide, in terms of its physicochemical characteristics, bioactive properties, and sensorial evaluation. The FucoPol-based cream, named F-cream, demonstrated stability over a period of 2 months at different temperatures, maintained desired organoleptic characteristics and pH, and showed minimal variations in viscosity. The F-cream exhibited suitable properties for anti-aging applications, including antioxidant capacity, effective photoprotection, and promotion of cellular preservation and migration.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2023)
Article
Biotechnology & Applied Microbiology
Patricia Concordio-Reis, Martim Cardeira, Ana Catarina Macedo, Sonia S. Ferreira, Ana Teresa Serra, Manuel A. Coimbra, Ana Amorim, Maria A. M. Reis, Filomena Freitas
Summary: This study identified a new dinoflagellate, Heterocapsa sp. AC210, as a producer of novel exopolysaccharides (EPS). The cultivation and EPS production in a bioreactor were thoroughly evaluated. The EPS consisted of seven different sugar monomers, including rare fucose and glucosamine not previously reported in dinoflagellates' EPS. The EPS also exhibited a high sulphate content, which is associated with biological properties. Cytotoxicity tests showed that the EPS did not reduce cell viability at concentrations up to 1 g L-1. Furthermore, antioxidant and anti-inflammatory assays demonstrated the potential application of the EPS in cosmeceutical and biomedical fields, as it reduced intracellular reactive oxygen species and IL-8 and IL-6 secretion in keratinocytes.
ALGAL RESEARCH-BIOMASS BIOFUELS AND BIOPRODUCTS
(2023)
Article
Food Science & Technology
Joana Madureira, Bruno Melgar, Vitor D. Alves, Margarida Moldao-Martins, Fernanda M. A. Margaca, Celestino Santos-Buelga, Lillian Barros, Sandra Cabo Verde
Summary: The efficiency of natural olive pomace extracts in enhancing the quality of fresh-cut apples and the effects of different packaging films were evaluated in this study. The results showed that the extracts effectively reduced microbial growth and maintained the phenolic content and antioxidant activity of the fruit. The combination of the extracts with the biodegradable PLA film packaging exhibited even better results. This research contributes to the development of natural food additives and sustainable practices in the olive oil industry.
Article
Materials Science, Multidisciplinary
Patricia Concordio-Reis, Kleyde Ramos, Ana Catarina Macedo, Ana Teresa Serra, Xavier Moppert, Jean Guezennec, Chantal Sevrin, Christian Grandfils, Maria A. M. Reis, Filomena Freitas
Summary: The marine isolate Alteromonas macleodii Mo 169 secretes an exopolysaccharide (EPS) that can be used to synthesize and stabilize silver and gold nanoparticles (AgNP and AuNP). The EPS possesses negatively charged functional groups, allowing it to function as a reducing agent and stabilizer for metallic nanoparticles. The synthesized nanoparticles showed promising physical-chemical and biological characteristics, including a polysaccharide layer that reduced aggregation and cytotoxicity. These findings demonstrate the potential of A. macleodii Mo 169 EPS for the development of novel biomaterials for wound care and other applications.
MATERIALS TODAY COMMUNICATIONS
(2023)
Article
Biochemistry & Molecular Biology
Kayo Santana Barros, Monica Carvalheira, Bruno Costa Marreiros, Maria Ascensao M. Reis, Joao Goulao Crespo, Valentin Perez-Herranz, Svetlozar Velizarov
Summary: For the production of polyhydroxyalkanoates (PHA) using nitrogen-rich feedstocks, the typical strategy of restricting cell growth by nitrogen limitation is not applicable. In this study, Donnan dialysis was evaluated as an alternative method to remove excess nitrogen ions by separating ammonium ions from volatile fatty acids in the media. The use of Fumasep and Ralex membranes showed better performance in terms of ammonium extraction compared to Ionsep.
Article
Biochemistry & Molecular Biology
Silvia Baptista, Filipa Baptista, Filomena Freitas
Summary: The main function of vitamin C is to combat free radicals and prevent premature aging. This study formulates oil-in-water emulsions stabilized with the bacterial polysaccharide FucoPol and evaluates their stability and performance in cosmetic formulations containing L-ascorbic acid.
Article
Biochemistry & Molecular Biology
Diana Araujo, Matilde Martins, Filomena Freitas
Summary: The polysaccharide FucoPol has shown great potential as a biomaterial in the biomedical field due to its good mechanical properties, biocompatibility, and anti-inflammatory activity. In this study, FucoPol hydrogel membranes (HMs) were loaded with caffeine or diclofenac sodium using diffusion or mixing methods. The diffusion method led to higher caffeine loading, while the mixing method resulted in higher diclofenac sodium loading. The HM1_DCAF membranes had increased mechanical and rheological parameters compared to the HM1_DDS membranes, possibly due to leaching during the drug-loading process. The release profiles showed fast release for diffusion-loaded membranes and prolonged release for mixing-loaded membranes. These findings support the suitability of FucoPol HMs as platforms for topical drug delivery.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Chemistry, Medicinal
Diana Araujo, Matilde Martins, Patricia Concordio-Reis, Catarina Roma-Rodrigues, Maria Morais, Vitor D. Alves, Alexandra R. Fernandes, Filomena Freitas
Summary: In this study, FucoPol, a fucose-rich polyanionic polysaccharide, was used for the preparation of hydrogel membranes (HMs) with Fe3+ as a crosslinking agent. The influence of Fe3+ and FucoPol concentrations on the strength of HMs was evaluated. The results showed that the FucoPol concentration had a more significant effect on the HMs' strength than the Fe3+ concentration. HMs with different FucoPol concentrations exhibited different microstructures and mechanical properties.
Article
Biology
Ichrak Joulak, Samia Azabou, Emilie Dumas, Filomena Freitas, Hamadi Attia, Adem Gharsallaoui
Summary: The current study investigates the spray-drying formation of microencapsulated geraniol powder using the exopolysaccharide EPS-K1B3 produced by Halomonas caseinilytica K1 as the wall material. The antimicrobial activity of the functional emulsions prepared at different pH values was evaluated against Listeria innocua and Escherichia coli. The results show that the microencapsulated geraniol powder exhibited prolonged antimicrobial efficacy, with the highest activity observed at pH 5 against L. innocua. This highlights the importance of pH in the functional properties of geraniol microcapsules.
Article
Biochemistry & Molecular Biology
Wei-Han Hui, Yen-Lin Chen, Shu-Wei Chang
Summary: Crosslinking affects the mechanical behavior and tissue metabolism of collagen-based tissues. Aging and diabetes alter the crosslinking type and density, thus changing tissue properties. High-connectivity enzymatic crosslinking and advanced-glycation end-products result in uniform deformation under daily activity, while low-connectivity enzymatic crosslinking does not. High-connectivity model displays more sliding, while AGEs induce instability in structures near the binding sites.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Yao-Bin Ma, Xiao-Qiu Zhou, Wei-Dan Jiang, Pei Wu, Yang Liu, Shu-Wei Li, Ling Tang, Lu Zhang, Hai-Feng Mi, Lin Feng
Summary: Tea polyphenols (TPs) are an inexpensive feed additive that can protect the gill function of fish against Flavobacterium columnare (F. columnare) through various mechanisms, including suppression of oxidative stress, apoptosis, and inflammation.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Yan-Jia Guo, Jing-Ru Pang, Yu Zhang, Zhong-Rui Li, Xiao-Lin Zi, Hong-Min Liu, Ning Wang, Li-Juan Zhao, Ya Gao, Bo Wang, Piet Herdewijn, Cheng-Yun Jin, Ying Liu, Yi-Chao Zheng
Summary: This study identifies the conjugation of NEDD8 to LSD1 and its impact on GC cells, revealing the significance of LSD1 neddylation in GC.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Review
Biochemistry & Molecular Biology
Geum-Jae Jeong, Fazlurrahman Khan, Nazia Tabassum, Young-Mog Kim
Summary: Vibrio species are motile gram-negative bacteria commonly found in aquatic environments. They can adapt to environmental fluctuations and develop protective mechanisms against host immune systems. Different types of sigma and anti-sigma factors play important roles in regulating gene expression and virulence in Vibrio species.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Zahra Mohammadbagheri, Behrooz Movahedi, Shaghayegh Saeedi, Abbas Rahmati
Summary: In this study, a reusable biobased composite hydrogel was successfully synthesized and used for the removal of Tl(I) from aqueous solutions. The hydrogel exhibited high adsorption capacity and thermal stability, and the adsorption process was found to be thermodynamically spontaneous. The results demonstrated that the hydrogel can be reused multiple times without significant loss of its adsorption capacity.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Iqra Batool, Muhammad Imran, Ayesha Anwar, Farhan Ahmed Khan, Afrah E. Mohammed, Ashwag Shami, Hafiz Iqbal
Summary: Enzyme immobilization on ZnO/SnO2 and ZnO/SnO2/SA nanocomposites was studied, and the catalytic and biochemical characteristics of the immobilized enzyme were investigated. The results showed that ZnO/SnO2 and ZnO/SnO2/SA nanostructures are suitable carriers for enzyme immobilization.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Elias Mosaffa, Dhruvi Patel, Nasim Amiri Ramsheh, Rishikumar Indravadan Patel, Atanu Banerjee, Hossein Ghafuri
Summary: In this study, a unique 3D bead structure of adsorbent, composed of bacterial cellulose microfilaments reinforced chitosan adorned with melamine 2D plates, was synthesized for anionic dye removal. The adsorbent showed high specific surface area and abundant functional groups, resulting in exceptional adsorption capacity. The characteristics and optimal conditions of the adsorbent were assessed and analyzed.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Carolina Gismene, Jorge Enrique Hernandez Gonzalez, Marilia de Freitas Calmon, Andrey Fabricio Ziem Nascimento, Angela Rocio Nino Santisteban, Felipe Antunes Calil, Alana Della Torre da Silva, Paula Rahal, Rejane Maira Goes, Raghuvir Krishnaswamy Arni, Ricardo Barros Mariutti
Summary: Mammaliicoccus sciuri, a bacterium of clinical and veterinary relevance, expresses the virulence factor Exfoliative Toxin C (ExhC), which binds specifically to desmoglein-1 (Dsg1) and plays a role in tissue integrity. This study investigates the necrotic activity of ExhC and identifies a variant lacking necrotic potential but retaining enzymatic activity through mutagenesis experiments and crystal structure determination.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Bibhas K. Bhunia, Ashutosh Bandyopadhyay, Souradeep Dey, Biman B. Mandal
Summary: Intervertebral disc degeneration is a major cause of chronic low back pain and disability. Researchers have developed a bioactive silk-based hybrid hydrogel system functionalized with decellularized human Wharton's jelly extracellular matrix as bioactive cues. The hydrogels mimic the rheological and mechanical properties of the native nucleus pulposus tissue and support cell viability, proliferation, and tissue maturation.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Qun Zhang, Yonggan Yan, Zhao Li, Jing Du, Kai Zhang, Liguo Zhang, Ting Wang, Alberto Bianco, Shaohua Ge, Baojin Ma
Summary: A new crosslinking strategy has been devised to construct injectable sodium alginate hydrogels, which can be regulated for injectability and have great potential in biomedical applications.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Seong Eun Hong, Ji-Soo Lee, Hyeon Gyu Lee
Summary: The potential of multi-layer nanoemulsions for improving the cellular uptake, antioxidant activity, and in vitro bioaccessibility of alpha-tocopherol was examined. The results showed that the multi-layer nanoemulsions significantly enhanced the cellular uptake and antioxidant activity of alpha-tocopherol compared to free coumarin 6. Furthermore, the use of chitosan and dextran sulfate as wall materials in the multi-layer nanoemulsions led to even higher cellular uptake, in vitro bioaccessibility, and antioxidant activity of alpha-tocopherol.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Jingjing Yu, Yanhui Zhang, Ruoning Zhang, Yanxiang Gao, Like Mao
Summary: High internal phase emulsions (HIPEs) based on beeswax (BW) oleogels and octenyl succinic acid starch (OSA starch) were prepared by a simple one-step method. The results showed that oleogelation improved the stability and encapsulation capability of the HIPEs, which is significant for the development of novel healthy food.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Review
Biochemistry & Molecular Biology
Bi-Feng Yao, Xiu-Ju Luo, Jun Peng
Summary: The balanced and continuous fission and fusion of mitochondria, regulated by OPA1, are important for maintaining mitochondrial dynamics in cardiovascular disorders. Understanding the role of OPA1 in mitochondrial fusion can provide insights into the pathogenesis of cardiovascular diseases.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Review
Biochemistry & Molecular Biology
Gokul Paramasivam, Anandhavelu Sanmugam, Vishnu Vardhan Palem, Murugan Sevanan, Ananda Babu Sairam, Nachiappan Nachiappan, Buhyun Youn, Jung Sub Lee, Muthuchamy Nallal, Kang Hyun Park
Summary: Nanomaterials are being used to deliver therapeutic agents in living systems. Different nanotechnological applications such as immunosensors, immune assays, and drug delivery are being implemented using nanotechnology. Genomics plays a crucial role in selecting appropriate drugs for personalized cancer therapy. It helps in analyzing gene and protein expression, disease classification, and designing disease models. Delivering drugs to specific areas using nanoparticles is a challenging issue.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Jing Li, Wei Wang, Han Wu, Feng Peng, Hui Gao, Ying Guan
Summary: In this study, CMH-based CPF films were prepared and their thermal and barrier properties were successfully regulated. The tensile strength and water vapor barrier property of CPF films were significantly improved, making them promising for food packaging applications.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
