Article
Physics, Applied
Sichao Li, Sunmi Shin
Summary: The upper limit of thermal conductivity mediated by long-range polaritons in asymmetric surrounding media was investigated. It was found that the thin film structure and asymmetric media can enhance the propagation of surface waves in free space, but fine tuning of the asymmetric permittivity is required to reach the maximum energy transmission efficiency.
JOURNAL OF APPLIED PHYSICS
(2023)
Article
Materials Science, Multidisciplinary
Duyu Chen, Xinyu Jiang, Duo Wang, Justine Ilyssa Vidallon, Houlong Zhuang, Yang Jiao
Summary: Medium-entropy alloys (MEAs) and high-entropy alloys (HEAs) are composed of mixtures of three or more elements in equal or relatively large proportions. They exhibit superior mechanical performance, unusual thermal and electronic transport properties, and resistance to corrosion. However, the atomic structures of these alloys are not well understood. In this study, a multihyperuniform (MH) model for disordered MEAs is developed, which suppresses composition fluctuations for atomic species and captures experimentally observed atomic short-range orders. The MH model provides predictions for lattice constants, electronic band gaps, and offers potential applications in optoelectronics and thermoelectrics.
Article
Chemistry, Multidisciplinary
Emil M. H. Larsen, Niels A. Bonde, Hogni Weihe, Jacques Ollivier, Tom Vosch, Thomas Lohmiller, Karsten Holldack, Alexander Schnegg, Mauro Perfetti, Jesper Bendix
Summary: This study reports the different magnetic exchange interactions between metal dimers and metal monomers. The existence of magnetic exchange interactions is related to the d(8)...d(8) metallophilic interaction between the filled Pt2+ 5d(z)(2) orbitals. Furthermore, this study experimentally confirms the influence of different metal bridges on magnetic coupling and presents a computational model for palladium metallophilic interactions.
Article
Multidisciplinary Sciences
Hanna Kranas, Irina Tuszynska, Bartek Wilczynski
Summary: HiCEnterprise is the first freely available software tool for the identification of long-range chromatin contacts, implementing four different statistical tests and user-friendly functions for input, output, and visualization. It is crucial for proper statistical analysis and open access to the research community.
Article
Multidisciplinary Sciences
Gil Koren, Sagi Meir, Lennard Holschuh, Haydyn D. T. Mertens, Tamara Ehm, Nadav Yahalom, Adina Golombek, Tal Schwartz, Dmitri I. Svergun, Omar A. Saleh, Joachim Dzubiella, Roy Beck
Summary: Short-range interactions and long-range contacts drive the folding of proteins. The structure of proteins directly affects their biological function. Nearly 40% of eukaryotes proteome is composed of intrinsically disordered proteins (IDPs) and protein regions that fluctuate between ensembles of numerous conformations. Polymer physics can, to some level, relate the IDP's sequence to its ensemble conformations, but long-range contacts between distant amino acids play a crucial role in determining intramolecular structures.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2023)
Article
Physics, Applied
Shengxuan Huang, Qingyang Hu
Summary: Natural occurring iron oxides have been abundant on Earth's surface since the Iron Age and have many implications in our daily life. They possess complicated magnetic and electronic properties, placing their physical research at the forefront of science. The introduction of pressure regulates the crystal structures and physical properties of iron oxides, creating new stoichiometry. Recent studies have discovered novel iron-oxygen compounds under different pressure-temperature conditions, with similar structural units forming complex stoichiometry. This perspective explores the formation mechanism of complex iron oxide crystals under high-pressure conditions, aiding in summarizing literary works and exploring new stoichiometry with optimal physical properties.
JOURNAL OF APPLIED PHYSICS
(2022)
Article
Engineering, Chemical
G. Violano, L. Afferrante
Summary: Tribologists have found that long and short-range adhesion have different effects on the pull-off force in viscoelastic fractures. In the case of long-range adhesion, the pull-off force is not affected by the unloading velocity, while in the case of short-range adhesion, the pull-off force increases monotonically with the pulling velocity and reaches a plateau at high speeds.
Article
Biochemistry & Molecular Biology
Alexandre Laverre, Eric Tannier, Anamaria Necsulea
Summary: This study investigates the evolutionary conservation of cis-regulatory landscapes involved in gene expression, showing a significant association between the evolution of cis-regulatory landscapes and gene expression. The research reveals that selective pressures act to preserve regulatory element sequences and their chromatin contacts with target genes across species. The conservation of long-range promoter-enhancer contacts plays a key role in constraining large-scale genome evolution.
Article
Chemistry, Inorganic & Nuclear
R. Alex Mayo, Ian S. Morgan, Dmitriy Soldatov, Rodolphe Clerac, Kathryn E. Preuss
Summary: A new radical ligand has been reported, with two crystal polymorphs identified. The self-assembly of Mn(II) metal ions with the ligand leads to a linear arrangement of three Mn(II) units bridged by two radical ligands. Magnetic measurements indicate effective ferromagnetic interactions along the supramolecular chain involving noncovalent S center dot center dot center dot O contacts.
INORGANIC CHEMISTRY
(2021)
Article
Agricultural Engineering
Maria Wennman, Anna J. Svagan, Marten Hellberg, Mikael S. Hedenqvist
Summary: Chemically bonded nonwovens are traditionally made with a latex binder containing plastic polymer and cellulosic fibers. However, they have low biodegradability and cannot be recycled. In this study, a biobased binder (PEC) made from carboxymethyl cellulose and chitosan dissolved in citric acid was combined with pea protein (PP) to create a fully biobased nonwoven with hydrophobic properties. By adjusting the fat content in PP and the protein content in the binder, different degrees of hydrophobicity and mechanical properties were achieved. The cured system showed a stable contact angle of around 120 degrees and significantly improved strength and stiffness compared to binder-free nonwovens in both dry and wet states.
INDUSTRIAL CROPS AND PRODUCTS
(2023)
Article
Biochemistry & Molecular Biology
Paul Campitelli, Liskin Swint-Kruse, S. Banu Ozkan
Summary: Substitutions at nonconserved protein positions can have noncanonical and long-distance effects on protein function, potentially resulting from changes in the internal protein communication network and structural flexibility. Substitutions were found to have long-range effects on flexibilities and dynamic coupling of DNA-binding positions, with the degree of flexibility change correlating with experimentally measured changes in DNA binding. This study proposes that long-range and noncanonical substitution outcomes arise from rewiring long-range communication among functionally important positions.
MOLECULAR BIOLOGY AND EVOLUTION
(2021)
Article
Biology
Tim Sainburg, Anna Mai, Timothy Q. Gentner
Summary: Human language relies on hierarchically organized, long-range relationships, which follow a power-law decay. This decay is not exclusive to linguistic structure, as non-linguistic behaviors in other species also demonstrate similar long-range statistical dependencies. In human speech, these statistical dependencies are present at the earliest detectable ages, prior to the production of complex linguistic structure.
PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES
(2022)
Article
Chemistry, Multidisciplinary
Jimin Guo, Shahrouz Amini, Qi Lei, Yuan Ping, Jacob Ongudi Agola, Lu Wang, Liang Zhou, Jiangfan Cao, Stefan Franco, Achraf Noureddine, Ali Miserez, Wei Zhu, C. Jeffrey Brinker
Summary: Freezing cells in amorphous silica is an effective method for long-term preservation of mammalian cell proteomic structure and function at room temperature, avoiding issues related to cryopreservation.
Article
Chemistry, Physical
Dian-Teng Chen, Jia Chen, Xiang-Guo Li, George Christou, Stephen Hill, Xiao-Guang Zhang, Hai-Ping Cheng
Summary: This work establishes a connection between density functional theory and Anderson's superexchange theory by constructing an f-d-p model with DFT Wannier functions. By applying this model to long-range magnetic interactions in a Mn-Ce magnetic molecule, insights about double-exchange and superexchange interactions are obtained. The dominant mechanism identified is the unusual superexchange between Mn atoms with different valence states.
JOURNAL OF PHYSICAL CHEMISTRY C
(2021)
Article
Biochemistry & Molecular Biology
Till El Harrar, Benedikt Frieg, Mehdi D. Davari, Karl-Erich Jaeger, Ulrich Schwaneberg, Holger Gohlke
Summary: This study investigates the impact of aqueous ionic liquids on a model enzyme through molecular dynamics simulations and finds that they can affect enzyme activity by modifying local structural stability, eventually leading to perturbations in the catalytic site and protein core. The identification of perturbation pathways and specific interactions with IL ions helps predict variant libraries with improved tolerance to aqueous ionic liquids.
COMPUTATIONAL AND STRUCTURAL BIOTECHNOLOGY JOURNAL
(2021)
Correction
Biochemical Research Methods
R. Prabakaran, Puneet Rawat, Sandeep Kumar, M. Michael Gromiha
BRIEFINGS IN BIOINFORMATICS
(2022)
Article
Biochemistry & Molecular Biology
R. Prabakaran, Puneet Rawat, Nobuaki Yasuo, Masakazu Sekijima, Sandeep Kumar, M. Michael Gromiha
Summary: The study investigated the aggregation of an APR (VLVIY) found in lambda light chains of human antibodies and its single point mutant KLVIY, showing that the Val->Lys mutation can resist aggregation and improve solubility by disrupting the APR. This mutation alters the solvation shell around the peptide, favoring solute-solvent interactions and increasing solubility.
PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS
(2022)
Article
Genetics & Heredity
Dhanusha Yesudhas, S. Akila Parvathy Dharshini, Y-H Taguchi, M. Michael Gromiha
Summary: This study analyzed single-cell transcriptome data of glioblastoma patients to understand the heterogeneity and prognosis mechanism of GBM, and identified potential disease-specific biomarkers.
Article
Biochemical Research Methods
Puneet Rawat, Divya Sharma, R. Prabakaran, Fathima Ridha, Mugdha Mohkhedkar, Vani Janakiraman, M. Michael Gromiha
Summary: Ab-CoV is a database containing manually curated experimental interaction profiles of 1780 coronavirus-related neutralizing antibodies. It provides comprehensive data including IC50, EC50, and K-D, as well as predicted changes in stability and affinity of point mutations of interface residues.
Review
Chemistry, Medicinal
Arulsang Kulandaisamy, Fathima Ridha, Dmitrij Frishman, M. Michael Gromiha
Summary: Membrane proteins play crucial roles in cellular functions, including serving as drug targets and mutations in these proteins can lead to diseases. Databases such as MutHTP and TMSNP provide data on disease-causing and neutral mutations in membrane proteins.
CURRENT TOPICS IN MEDICINAL CHEMISTRY
(2022)
Article
Biochemical Research Methods
Medha Pandey, P. Anoosha, Dhanusha Yesudhas, M. Michael Gromiha
Summary: Glioblastoma is an aggressive brain and spinal cord tumor, and mutations in specific amino acid residues are associated with the disease. This study identified driver mutations preferredly containing Arg and passenger mutations preferredly containing Met and Ile. The study also revealed different motifs and neighboring residues preferences between driver and passenger mutations. By utilizing sequence-based features and machine learning, a method called GBMDriver was developed to distinguish between driver and passenger mutations with high accuracy. This method has great potential in prioritizing driver mutations and identifying therapeutic targets in glioblastoma.
BRIEFINGS IN BIOINFORMATICS
(2022)
Article
Oncology
Vishnupriya Kanakaveti, Sakthivel Ramasamy, Rahul Kanumuri, Vaishnavi Balasubramanian, Roshni Saravanan, Inemai Ezhil, Ravishankar Pitani, Ganesh Venkatraman, Suresh Kumar Rayala, M. Michael Gromiha
Summary: This study identified three novel BH4 mimetics that exhibit nanomolar activities against triple-negative breast cancer cells. These compounds induce apoptosis and have high specificity towards cancer cells. They show promising potential for clinical translation in targeting this challenging subtype of breast cancer.
Review
Chemistry, Medicinal
Anusuya Shanmugam, Anbazhagan Venkattappan, M. Michael Gromiha
Summary: The COVID-19 pandemic has led to increased research on the SARS-CoV-2 spike protein for drug design. This review summarizes various structure-based drug design approaches applied to this protein, including molecular docking, virtual screening, molecular dynamics simulation, drug repurposing, and pharmacophore modeling and screening.
CURRENT TOPICS IN MEDICINAL CHEMISTRY
(2022)
Article
Genetics & Heredity
Nela Pragathi Sneha, S. Akila Parvathy Dharshini, Y. -h. Taguchi, M. Michael Gromiha
Summary: Huntington's disease is a neurodegenerative disorder characterized by the vulnerability of striatal projection neurons. Variants in gene expression and miRNA binding are found to affect the regulatory functions, disrupt transcription factor networks, and contribute to abnormal neuroinflammation. Furthermore, mitochondrial dysfunction, neuroinflammation, and disrupted vasculature play a role in blood-brain barrier dysfunction and abnormal energy metabolism. Restoring blood-brain barrier functionality and energy metabolism may be potential therapeutic strategies for protecting neurons in Huntington's disease.
Letter
Biotechnology & Applied Microbiology
M. Michael Gromiha, Kannan Harini
Summary: Mei and colleagues introduced PNATDB, a thermodynamic database for protein-nucleic acid interactions with 12,635 experimentally determined parameters. They claimed that extracting data from existing databases is challenging. However, they did not discuss ProNAB, which contains over 20,000 experimental data points for binding affinities of protein-nucleic acid complexes and other information.
TRENDS IN BIOTECHNOLOGY
(2023)
Article
Genetics & Heredity
Sankaran Venkatachalam, Nisha Murlidharan, Sowmya R. Krishnan, C. Ramakrishnan, Mpho Setshedi, Ramesh Pandian, Debmalya Barh, Sandeep Tiwari, Vasco Azevedo, Yasien Sayed, M. Michael Gromiha
Summary: AIDS is a challenging infectious disease with a need for understanding drug resistance mechanisms. A new double-insertion mutation (L38HL) in HIV subtype C protease was investigated for its potential in inducing drug resistance towards the protease inhibitor Saquinavir (SQV). Computational techniques revealed that the L38HL mutation increased flexibility in certain regions and decreased binding affinity of SQV compared to wild-type. The mutation also resulted in a wide opening at the binding site and altered flap dynamics, leading to decreased interactions with the binding site and a potential drug resistance phenotype.
Article
Chemistry, Medicinal
Sowmya Ramaswamy Krishnan, Ruben R. G. Soares, Narayanan Madaboosi, M. Michael Gromiha
Summary: The emergence of new zoonotic infections among humans has increased the burden on global healthcare systems to control their spread. To address this, a novel and integrated PLP design pipeline called AutoPLP has been developed, which can automate the probe design process for a diverse pathogen panel of interest.
ACS INFECTIOUS DISEASES
(2023)
Article
Biochemical Research Methods
Jianfeng Sun, Arulsamy Kulandaisamy, Jinlong Ru, M. Michael Gromiha, Adam P. Cribbs
Summary: TMKit is an open-source Python programming interface specifically designed for processing transmembrane protein data. It includes tools for database wrangling, feature engineering, and protein-protein interaction visualization. Additionally, it offers the high-performance computing library seqNetRR for fast construction of residue connections and allocation of correlation matrix-based features. TMKit serves as a useful tool for researchers studying transmembrane protein sequences and structures.
BRIEFINGS IN BIOINFORMATICS
(2023)
Article
Genetics & Heredity
Nela Pragathi Sneha, S. Akila Parvathy Dharshini, Y. -H Taguchi, M. Michael Gromiha
Summary: In this study, the relationship between genetic variants and differentially expressed genes/transcripts in the BA4 region of Huntington's disease patients was investigated. The study identified variants that regulate gene expression and highlighted variants affecting miRNA and its targets. Co-expression network analysis revealed the role of novel genes, while function interaction network analysis showed the importance of genes involved in vesicle-mediated transport. The study also emphasized the crucial role of genes expressed in immune cells in reducing neuron death in Huntington's disease.
Article
Biochemistry & Molecular Biology
Fathima Ridha, M. Michael Gromiha
Summary: Membrane protein-protein interactions are crucial for cellular functions. This study collected experimental data of membrane protein-protein complexes and derived features to understand the factors influencing binding affinity. A machine learning method, MPA-Pred, was developed to predict the binding affinity and showed high accuracy in the prediction.
PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS
(2023)
Article
Biochemistry & Molecular Biology
Wei-Han Hui, Yen-Lin Chen, Shu-Wei Chang
Summary: Crosslinking affects the mechanical behavior and tissue metabolism of collagen-based tissues. Aging and diabetes alter the crosslinking type and density, thus changing tissue properties. High-connectivity enzymatic crosslinking and advanced-glycation end-products result in uniform deformation under daily activity, while low-connectivity enzymatic crosslinking does not. High-connectivity model displays more sliding, while AGEs induce instability in structures near the binding sites.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Yao-Bin Ma, Xiao-Qiu Zhou, Wei-Dan Jiang, Pei Wu, Yang Liu, Shu-Wei Li, Ling Tang, Lu Zhang, Hai-Feng Mi, Lin Feng
Summary: Tea polyphenols (TPs) are an inexpensive feed additive that can protect the gill function of fish against Flavobacterium columnare (F. columnare) through various mechanisms, including suppression of oxidative stress, apoptosis, and inflammation.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Yan-Jia Guo, Jing-Ru Pang, Yu Zhang, Zhong-Rui Li, Xiao-Lin Zi, Hong-Min Liu, Ning Wang, Li-Juan Zhao, Ya Gao, Bo Wang, Piet Herdewijn, Cheng-Yun Jin, Ying Liu, Yi-Chao Zheng
Summary: This study identifies the conjugation of NEDD8 to LSD1 and its impact on GC cells, revealing the significance of LSD1 neddylation in GC.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Review
Biochemistry & Molecular Biology
Geum-Jae Jeong, Fazlurrahman Khan, Nazia Tabassum, Young-Mog Kim
Summary: Vibrio species are motile gram-negative bacteria commonly found in aquatic environments. They can adapt to environmental fluctuations and develop protective mechanisms against host immune systems. Different types of sigma and anti-sigma factors play important roles in regulating gene expression and virulence in Vibrio species.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Zahra Mohammadbagheri, Behrooz Movahedi, Shaghayegh Saeedi, Abbas Rahmati
Summary: In this study, a reusable biobased composite hydrogel was successfully synthesized and used for the removal of Tl(I) from aqueous solutions. The hydrogel exhibited high adsorption capacity and thermal stability, and the adsorption process was found to be thermodynamically spontaneous. The results demonstrated that the hydrogel can be reused multiple times without significant loss of its adsorption capacity.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Iqra Batool, Muhammad Imran, Ayesha Anwar, Farhan Ahmed Khan, Afrah E. Mohammed, Ashwag Shami, Hafiz Iqbal
Summary: Enzyme immobilization on ZnO/SnO2 and ZnO/SnO2/SA nanocomposites was studied, and the catalytic and biochemical characteristics of the immobilized enzyme were investigated. The results showed that ZnO/SnO2 and ZnO/SnO2/SA nanostructures are suitable carriers for enzyme immobilization.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Elias Mosaffa, Dhruvi Patel, Nasim Amiri Ramsheh, Rishikumar Indravadan Patel, Atanu Banerjee, Hossein Ghafuri
Summary: In this study, a unique 3D bead structure of adsorbent, composed of bacterial cellulose microfilaments reinforced chitosan adorned with melamine 2D plates, was synthesized for anionic dye removal. The adsorbent showed high specific surface area and abundant functional groups, resulting in exceptional adsorption capacity. The characteristics and optimal conditions of the adsorbent were assessed and analyzed.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Carolina Gismene, Jorge Enrique Hernandez Gonzalez, Marilia de Freitas Calmon, Andrey Fabricio Ziem Nascimento, Angela Rocio Nino Santisteban, Felipe Antunes Calil, Alana Della Torre da Silva, Paula Rahal, Rejane Maira Goes, Raghuvir Krishnaswamy Arni, Ricardo Barros Mariutti
Summary: Mammaliicoccus sciuri, a bacterium of clinical and veterinary relevance, expresses the virulence factor Exfoliative Toxin C (ExhC), which binds specifically to desmoglein-1 (Dsg1) and plays a role in tissue integrity. This study investigates the necrotic activity of ExhC and identifies a variant lacking necrotic potential but retaining enzymatic activity through mutagenesis experiments and crystal structure determination.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Bibhas K. Bhunia, Ashutosh Bandyopadhyay, Souradeep Dey, Biman B. Mandal
Summary: Intervertebral disc degeneration is a major cause of chronic low back pain and disability. Researchers have developed a bioactive silk-based hybrid hydrogel system functionalized with decellularized human Wharton's jelly extracellular matrix as bioactive cues. The hydrogels mimic the rheological and mechanical properties of the native nucleus pulposus tissue and support cell viability, proliferation, and tissue maturation.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Qun Zhang, Yonggan Yan, Zhao Li, Jing Du, Kai Zhang, Liguo Zhang, Ting Wang, Alberto Bianco, Shaohua Ge, Baojin Ma
Summary: A new crosslinking strategy has been devised to construct injectable sodium alginate hydrogels, which can be regulated for injectability and have great potential in biomedical applications.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Seong Eun Hong, Ji-Soo Lee, Hyeon Gyu Lee
Summary: The potential of multi-layer nanoemulsions for improving the cellular uptake, antioxidant activity, and in vitro bioaccessibility of alpha-tocopherol was examined. The results showed that the multi-layer nanoemulsions significantly enhanced the cellular uptake and antioxidant activity of alpha-tocopherol compared to free coumarin 6. Furthermore, the use of chitosan and dextran sulfate as wall materials in the multi-layer nanoemulsions led to even higher cellular uptake, in vitro bioaccessibility, and antioxidant activity of alpha-tocopherol.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Jingjing Yu, Yanhui Zhang, Ruoning Zhang, Yanxiang Gao, Like Mao
Summary: High internal phase emulsions (HIPEs) based on beeswax (BW) oleogels and octenyl succinic acid starch (OSA starch) were prepared by a simple one-step method. The results showed that oleogelation improved the stability and encapsulation capability of the HIPEs, which is significant for the development of novel healthy food.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Review
Biochemistry & Molecular Biology
Bi-Feng Yao, Xiu-Ju Luo, Jun Peng
Summary: The balanced and continuous fission and fusion of mitochondria, regulated by OPA1, are important for maintaining mitochondrial dynamics in cardiovascular disorders. Understanding the role of OPA1 in mitochondrial fusion can provide insights into the pathogenesis of cardiovascular diseases.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Review
Biochemistry & Molecular Biology
Gokul Paramasivam, Anandhavelu Sanmugam, Vishnu Vardhan Palem, Murugan Sevanan, Ananda Babu Sairam, Nachiappan Nachiappan, Buhyun Youn, Jung Sub Lee, Muthuchamy Nallal, Kang Hyun Park
Summary: Nanomaterials are being used to deliver therapeutic agents in living systems. Different nanotechnological applications such as immunosensors, immune assays, and drug delivery are being implemented using nanotechnology. Genomics plays a crucial role in selecting appropriate drugs for personalized cancer therapy. It helps in analyzing gene and protein expression, disease classification, and designing disease models. Delivering drugs to specific areas using nanoparticles is a challenging issue.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Jing Li, Wei Wang, Han Wu, Feng Peng, Hui Gao, Ying Guan
Summary: In this study, CMH-based CPF films were prepared and their thermal and barrier properties were successfully regulated. The tensile strength and water vapor barrier property of CPF films were significantly improved, making them promising for food packaging applications.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)