Article
Cardiac & Cardiovascular Systems
Viktor Lind, Niklas Hammar, Pia Lundman, Leif Friberg, Mats Talback, Goran Walldius, Anna Norhammar
Summary: Dysglycaemia, even at prediabetes levels, is associated with an increased risk of developing atrial fibrillation and heart failure. The study found that individuals with diagnosed diabetes had the highest risk. However, the associations were somewhat weakened when BMI data was taken into account, with only diagnosed diabetes remaining statistically significant for atrial fibrillation.
CARDIOVASCULAR DIABETOLOGY
(2021)
Article
Endocrinology & Metabolism
Yingting Zuo, Xinsheng Han, Xue Tian, Shuohua Chen, Shouling Wu, Anxin Wang
Summary: The study revealed that individuals without traditional ASCVD risk factors are at increased risk of developing CVD with higher levels of abnormal fasting plasma glucose, underlining the importance of prevention strategies targeting elevated FPG levels in addition to other traditional ASCVD risk factors.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2022)
Article
Cell Biology
Chang Chen, Yequn Chen, Jiaxin Xiao, Yanhong Zhang, Zhaorui Yang, Peixuan Yang, Nan Lu, Kaihong Yi, Xiaojun Chen, Shaoxin Chen, Mary Clare O'Gara Msc, Michael O'Meara, Shu Ye, Xuerui Tan
Summary: There is an association between impaired fasting glucose level and a predisposition to severe coronary artery disease indicated by triple vessel disease or myocardial infarction.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY
(2022)
Article
Public, Environmental & Occupational Health
Xin Zhang, Yankun Yue, Shaobo Liu, Xiangfeng Cong, Wenjuan Wang, Jianhong Li
Summary: This study investigates the relationship between BMI and the risk of impaired glucose tolerance (IGT) and impaired fasting glucose (IFG) in Chinese adults. The results show that obesity is an important risk factor for IGT and IFG in China, and the risk of IGT increases during the overweight stage.
Article
Medicine, General & Internal
Fei Xu, Xiang Ning, Tong Zhao, Qinghua Lu, Huiqiang Chen
Summary: The serum visfatin levels in non-diabetic subjects were found to be associated with the presence and severity of coronary artery disease (CAD). The study showed significantly lower serum visfatin levels in patients with CAD compared to those with normal coronary arteries, while fasting glucose levels were elevated in CAD patients. Both visfatin and impaired fasting glucose (IFG) were independently associated with the presence of CAD in non-diabetics. Furthermore, serum visfatin levels were negatively related to the severity of CAD in subjects with IFG. These findings suggest that visfatin may play an important role in the development of CAD.
Article
Nutrition & Dietetics
Han Shi, Yusong Ge, Hongming Wang, Yun Zhang, Weiyu Teng, Li Tian
Summary: The study revealed a positive relationship between fasting blood glucose and stroke risk, with a non-linear dose-response association. In non-diabetic populations, the association between high fasting blood glucose and stroke risk was lower compared to the general population.
CLINICAL NUTRITION
(2021)
Article
Cardiac & Cardiovascular Systems
Jinyu Su, Zhu Li, Mengnan Huang, Yang Wang, Tong Yang, Mei Ma, Tongyao Ni, Guangwei Pan, Ziqin Lai, Chunjie Li, Lin Li, Chunquan Yu
Summary: This study found that TyG index is associated with the severity of coronary artery disease (CAD) in patients with coronary heart disease (CHD), and an increased TyG index can identify patients with a high risk of multi-vessel CAD. The association between TyG index and CAD severity was significant in patients with diabetes mellitus (DM).
CARDIOVASCULAR DIABETOLOGY
(2022)
Article
Endocrinology & Metabolism
Shishi Xu, Charles A. B. Scott, Ruth L. Coleman, Jaakko Tuomilehto, Rury R. Holman
Summary: This study developed a Chinese type 2 diabetes risk calculator using ACE trial data, which can estimate diabetes risk in Chinese patients with coronary heart disease and impaired glucose tolerance using clinically relevant variables and laboratory results.
JOURNAL OF DIABETES
(2021)
Article
Endocrinology & Metabolism
Lu Yu, Zhu Li, Rongrong Yang, Guangwei Pan, Qi Cheng, Yuanyuan He, Yijia Liu, Fanfan Liu, Mei Ma, Tong Yang, Yang Wang, Jinyu Su, Yanchao Zheng, Shan Gao, Qiang Xu, Lin Li, Chunquan Yu
Summary: The study revealed a significant association between thyroid hormone sensitivity and elevated blood glucose in patients with coronary heart disease. This association was higher in females compared to males and in patients aged over 60 years old than those aged 60 and below.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Article
Behavioral Sciences
Xuan Liang, Yilin Huang, Xu Han
Summary: In summary, this meta-analysis found that coronary heart disease is significantly associated with an increased risk of cognitive impairment, including myocardial infarction. However, no significant association was found between angina pectoris and cognitive impairment. Subgroup studies also indicated that CHD patients are at higher risk for vascular dementia.
BRAIN AND BEHAVIOR
(2021)
Article
Cardiac & Cardiovascular Systems
Hernan Mejia-Renteria, Alejandro Travieso, Jordi A. Matias-Guiu, Miguel Yus, Carolina Espejo-Paeres, Francesca Finocchiaro, Sara Fernandez, Carlos Ignacio Gomez-Escalonilla, Blanca Reneses-Prieto, Maria Dulcenombre Gomez-Garre, Alfonso Delgado-Alvarez, Ana Bustos, Leopoldo Perez de Isla, Jose Juan Gomez de Diego, Javier Modrego-Martin, Adriana Ortega-Hernandez, Petros Papadopoulos, Juan Arrazola-Garcia, Jorge Matias-Guiu, Javier Escaned
Summary: This study reveals the correlation between coronary microcirculatory dysfunction in patients with coronary artery disease (CAD) and cerebral small vessel disease (CSVD), as well as cognitive impairment.
EUROPEAN HEART JOURNAL
(2023)
Article
Cardiac & Cardiovascular Systems
Qiuzhen Lin, Yan Fu, Xue Yan Zang, Qiming Liu, Ling Liu
Summary: The study found that in patients with coronary heart disease, fasting LDL-C levels significantly influenced the changes in non-fasting LDL-C levels. When fasting LDL-C levels were lower, the changes in non-fasting LDL-C levels were also smaller.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2021)
Article
Cardiac & Cardiovascular Systems
Chenxi Song, Sheng Yuan, Kongyong Cui, Zhongxing Cai, Rui Zhang, Jining He, Zheng Qiao, Xiaohui Bian, Shaoyu Wu, Haoyu Wang, Boqun Shi, Zhangyu Lin, Rui Fu, Chunyue Wang, Qianqian Liu, Lei Jia, Qiuting Dong, Kefei Dou
Summary: This study aimed to investigate the impact of prediabetes on the prognosis of patients with coronary intermediate lesions and compare the prognostic value of different definitions of prediabetes. The study found that prediabetes based on the IEC-HbA1c definition (6.0 <= HbA1c < 6.5%) was associated with an increased risk of major adverse cardiovascular events (MACE) compared to normal glucose tolerance. These findings suggest that early lifestyle intervention may benefit high-risk patients with prediabetes.
CARDIOVASCULAR DIABETOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Procolo Di Bonito, Giuliana Valerio, Maria R. Licenziati, Giuseppina Campana, Emanuele M. del Giudice, Anna Di Sessa, Anita Morandi, Claudio Maffeis, Claudio Chiesa, Lucia Pacifico, Marco G. Baroni, Melania Manco
Summary: The study revealed a significant association between uric acid levels and markers of prediabetes, insulin resistance, and insulin sensitivity in overweight/obese youth. Higher uric acid levels were correlated with elevated markers of impaired glucose metabolism, particularly post-challenge conditions.
NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES
(2021)
Article
Endocrinology & Metabolism
Mee Kyoung Kim, Kyungdo Han, Eun Sil Koh, Oak-Kee Hong, Ki-Hyun Baek, Ki-Ho Song, Hyuk-Sang Kwon
Summary: The status of metabolic abnormalities, including impaired fasting glucose (IFG), can change over time. Using data from the Korean National Health Insurance system, the study found that cumulative exposure to IFG was associated with a higher risk of type 2 diabetes mellitus in a dose-response fashion.
DIABETES RESEARCH AND CLINICAL PRACTICE
(2021)