Article
Nutrition & Dietetics
Anne Krijger, Elly Steenbergen, Lieke Schiphof-Godart, Caroline van Rossum, Janneke Verkaik-Kloosterman, Liset Elstgeest, Sovianne ter Borg, Hein Raat, Koen Joosten
Summary: This study aimed to identify clusters of lifestyle behaviors in toddlers and evaluate their associations with socio-demographic characteristics. The results showed that lifestyle behaviors in 1-3 year-old children can be divided into three clusters, with certain socio-demographic characteristics associated with cluster allocation. This study highlights the importance of intervening in healthy lifestyle behaviors from early childhood.
EUROPEAN JOURNAL OF NUTRITION
(2023)
Article
Public, Environmental & Occupational Health
Pravesh Sharma, Quang Anh Nguyen, Shaheen Kurani, Ashley Holland, Hilal Maradit Kremers, Vanessa Pazdernik, Jennifer St Sauver, Paul Croarkin, Celia Kamath, Jennifer Geske, Kavita Prasad, Amy Glasgow, Lindsey Sangaralingham, Christi Patten
Summary: During the COVID-19 pandemic, women, younger individuals, those living in rural areas, and smokers were more likely to initiate alcohol use. Targeted screening and intervention for vulnerable individuals are necessary.
JOURNAL OF PUBLIC HEALTH
(2023)
Article
Multidisciplinary Sciences
Suzanne J. van den Toren, Amy van Grieken, Hein Raat
Summary: Research shows that adolescent nitrous oxide use is associated with factors such as ethnic background, education levels, mental health issues, binge drinking, and cannabis use.
Article
Substance Abuse
Inger Synnove Moan, Torleif Halkjelsvik
Summary: The study estimated the prevalence of alcohol-related presenteeism among Norwegian adults at 8.7%. Men and younger employees had a higher risk, as did those with higher education and income.
Article
Nutrition & Dietetics
Ayse Gunes-Bayir, Zelal Tandogan, Ozge Gedik-Toker, Aysegul Yabaci-Tak, Agnes Dadak
Summary: Dizziness and vertigo are associated with female gender and increasing age. The patient group had a higher rate of obesity, skipped meals on a daily basis with lunch being the most frequently skipped meal. The dietary intake of carotene and vitamin K was lower in the patient group, while the intake of vitamin D was higher. The patient group consumed more bread and dairy products and engaged in less physical activity.
Article
Multidisciplinary Sciences
Hugo Pereira, Antonio L. Palmeira, Eliana Carraca, Ines Santos, Marta M. Marques, Pedro J. Teixeira
Summary: This study cross-sectionally estimated the prevalence of recreational running in Portugal, finding that 10.6% of adults regularly ran, with higher rates among men and younger individuals. The study also identified general health orientation, self-esteem, and life meaning as the main motivators for running, while time was the most common barrier.
Article
Clinical Neurology
Sarah Cook, Lyudmila Saburova, Natalia Bobrova, Ekaterina Avdeeva, Sofia Malyutina, Alexander Kudryavtsev, David A. Leon
Summary: This study identified various risk factors for depression in the general population of Russia, including gender, financial constraints, employment status, alcohol use, smoking, social support, and life events. Financial constraints, problem drinking, and life events showed particularly strong associations with depression risk.
JOURNAL OF AFFECTIVE DISORDERS
(2021)
Article
Substance Abuse
Mohammad Z. Haque, Stephanie W. Young, Ying Wang, Shelley Harris, Norman Giesbrecht, Maria Chu, Rebecca Truscott
Summary: The study found that multiple socio-demographic factors are associated with binge drinking, including younger age groups, lower educational attainment, lower household income, recent immigrants, males, poorer mental health, single status, rural residence, and unemployment. These factors remained significant when stratified by sex.
DRUG AND ALCOHOL DEPENDENCE
(2021)
Article
Biology
Marzena Jezewska-Zychowicz, Robert Gajda
Summary: Maintaining good health for the elderly is a great challenge, and it is important to identify risk factors affecting them. This study explored the relationships between sociodemographic characteristics, diet, physical activity, and metabolic diseases and impaired mobility in Polish elderly. The results showed that being overweight or obese and having a certain diet increased the likelihood of metabolic diseases, while education level, financial situation, perception of one's health, and physical activity decreased the probability of mobility impairments. Eating behaviors did not predict the disease, but they differentiated the clusters.
Article
Geriatrics & Gerontology
Irene N. Fierloos, Siok Swan Tan, Greg Williams, Tamara Alhambra-Borras, Elin Koppelaar, Lovorka Bilajac, Arpana Verma, Athina Markaki, Francesco Mattace-Raso, Vanja Vasiljev, Carmen B. Franse, Hein Raat
Summary: This study examined the socio-demographic characteristics associated with emotional and social loneliness among older adults. The results showed that factors such as age, gender, living situation, and educational level influenced the experience of loneliness differently. Older age, living without a partner, and having a low educational level were associated with increased emotional and social loneliness in this population.
Article
Environmental Sciences
Ole Raaschou-Nielsen, Tahir Taj, Aslak H. Poulsen, Ulla A. Hvidtfeldt, Matthias Ketzel, Jesper H. Christensen, Jorgen Brandt, Lise M. Frohn, Camilla Geels, Victor H. Valencia, Mette Sorensen
Summary: This study investigates the associations between air pollution and socio-demographic variables, comorbidity, stress, and green space at the residence in Denmark. The results show that individuals with higher socioeconomic status and non-Danish origin are exposed to higher levels of air pollution. However, there is no consistent pattern observed for neighborhood-level indicators of socioeconomic status. People living in apartments or with little green space also have higher air pollution levels.
ENVIRONMENTAL RESEARCH
(2022)
Article
Plant Sciences
Geir Aamodt, Helena Nordh, Emma C. A. Nordbo
Summary: Urban green space is important for providing health promoting facilities, but unequal distribution among socio-demographic and socio-economic groups can lead to environmental injustice. This study explores the relationships between characteristics of residents and their access to different types of green space in four Nordic cities. The results show variations in access and proportions of green space between and within the cities, with differences based on age, education, immigration status, and income.
URBAN FORESTRY & URBAN GREENING
(2023)
Article
Hospitality, Leisure, Sport & Tourism
Asli D. A. Tasci, Alan Fyall, Kyle Maurice Woosnam
Summary: This study aims to uncover the characteristics of sustainable consumers through an analysis of socio-demographic, psychographic, and behavioral traits. The findings suggest that individuals who consider themselves as sustainable consumers are more likely to have ethical views, be more feminine and liberal in personality, show concern for environmental and social sustainability issues, attribute responsibility for sustainability to all relevant parties, and prefer alternative forms of tourism over mass tourism. The results provide valuable insights for the industry to target sustainable tourism consumers.
Article
Public, Environmental & Occupational Health
Ruwan Jayathilaka, Harindu Adikari, Rangi Liyanage, Rumesh Udalagama, Nuwan Wanigarathna
Summary: This study investigated the socio-economic and demographic characteristics associated with child mortality in Sri Lanka using data from a national survey. The results showed that place of residence province-wise, household head's education level, and source of drinking water have a negative effect on child mortality in Sri Lanka. The Western province had the highest negative effect on child mortality, while household heads owning private entities and Sri Lankan Moors had a positive effect on child mortality.
Article
Biology
Manoj Kaushik, Rakesh Chandra Joshi, Atar Singh Kushwah, Maneesh Kumar Gupta, Monisha Banerjee, Radim Burget, Malay Kishore Dutta
Summary: This study utilized machine learning models to analyze the risk factors of cervical cancer, focusing on cytokine gene variants and socio-demographic characteristics, to provide better prognosis and prediction. After evaluating various machine learning approaches, logistic regression technique achieved the highest accuracy and F1-score, while ridge classifiers and Gaussian Naive Bayes classifiers demonstrated the highest sensitivity. The study suggests that the analysis of cytokine gene variants and socio-demographic characteristics with machine learning can effectively predict the risk of developing cervical cancer.
COMPUTERS IN BIOLOGY AND MEDICINE
(2021)
Article
Neurosciences
Fabien Dumetz, Rachel Ginieis, Corinne Bure, Anais Marie, Serge Alfos, Veronique Pallet, Clementine Bosch-Bouju
Summary: This study investigates the effects of vitamin A deficiency on memory and neuronal plasticity in the hippocampus of rats. The findings suggest that vitamin A deficiency leads to abnormal morphology and synaptic function in hippocampal cells, and moderate-dose vitamin A supplementation can alleviate these abnormalities.
NUTRITIONAL NEUROSCIENCE
(2022)
Article
Clinical Neurology
Andrea Du Preez, Sophie Lefevre-Arbogast, Vikki Houghton, Chiara de Lucia, Dorrain Y. Low, Catherine Helmer, Catherine Feart, Cecile Delcourt, Cecile Proust-Lima, Merce Pallas, Silvie R. Ruigrok, Barbara Altendorfer, Raul Gonzalez-Dominguez, Alex Sanchez-Pla, Mireia Urpi-Sarda, Cristina Andres-Lacueva, Ludwig Aigner, Paul J. Lucassen, Aniko Korosi, Claudine Manach, Cecilia Samieri, Sandrine Thuret
Summary: Diet and exercise can influence neurogenesis prior to the onset of cognitive decline and dementia, with changes in hippocampal neurogenesis potentially serving as biomarkers for future risk of CD and dementia. Apoptosis plays a key role in mediating the effects of diet and exercise on cognitive decline.
ALZHEIMERS & DEMENTIA
(2022)
Article
Clinical Neurology
Cecilia Samieri, Hussein N. Yassine, Debora Melo van Lent, Sophie Lefevre-Arbogast, Ondine van de Rest, Gene L. Bowman, Nikolaos Scarmeas
Summary: Personalized nutrition may offer advantages in preventing dementia by incorporating individuals' dietary exposure history and biological characteristics to shape health more effectively. Further research from observational epidemiology to basic science is needed to achieve better prevention outcomes.
ALZHEIMERS & DEMENTIA
(2022)
Review
Biochemistry & Molecular Biology
Sophie Lefevre-Arbogast, Aline Thomas, Cecilia Samieri
Summary: The purpose of this review is to examine the relationship between nutrition and brain health. Recent epidemiological studies have provided new insights into the impact of diet and nutrients on cognitive aging. The findings suggest that specific diets and nutrients, such as the Mediterranean diet and LC n-3 polyunsaturated fatty acids, may prevent cognitive decline. Additionally, diet management approaches, like the Modified Mediterranean-ketogenic diet, show promise for preventing neurodegenerative diseases. Promoting a healthy gut microbiome through prebiotic foods is also highlighted as an important factor in maintaining the diet-gut-brain axis with aging. Future research should focus on individualized preventive approaches through a precision nutrition framework.
CURRENT OPINION IN LIPIDOLOGY
(2022)
Article
Neurosciences
Jeanne Neuffer, Marjorie Gourru, Aline Thomas, Sophie Lefevre-Arbogast, Alexandra Foubert-Samier, Catherine Helmer, Cecile Delcourt, Catherine Feart, Cecilia Samieri
Summary: A study developed an index of micronutritional biological status (MNBS) to screen for multiple micronutritional deficiencies associated with the risk of dementia in older adults. The study found that an increase in the MNBS index was associated with a higher risk of dementia.
JOURNAL OF ALZHEIMERS DISEASE
(2022)
Article
Clinical Neurology
Morgane Linard, Julien Bezin, Emilie Hucteau, Pierre Joly, Isabelle Garrigue, Jean-Francois Dartigues, Antoine Pariente, Catherine Helmer
Summary: Using a French medico-administrative database, this study found that taking at least one systemic antiherpetic drug (AHD) during follow-up was significantly associated with a 15% reduced risk of developing Alzheimer's disease (AD).
ALZHEIMERS RESEARCH & THERAPY
(2022)
Article
Clinical Neurology
Clemence Cavailles, Claudine Berr, Catherine Helmer, Audrey Gabelle, Isabelle Jaussent, Yves Dauvilliers
Summary: Sleep disturbances are associated with dementia in the elderly, with excessive daytime sleepiness and hypnotics increasing the risk of dementia, while insomnia complaints and sleep quality are unrelated. Further research is needed to determine if managing sleep disturbances can prevent dementia.
ALZHEIMERS RESEARCH & THERAPY
(2022)
Article
Clinical Neurology
Raul Gonzalez-Dominguez, Pol Castellano-Escuder, Sophie Lefevre-Arbogast, Dorrain Y. Low, Andrea Du Preez, Silvie R. Ruigrok, Hyunah Lee, Catherine Helmer, Merce Pallas, Mireia Urpi-Sarda, Alex Sanchez-Pla, Aniko Korosi, Paul J. Lucassen, Ludwig Aigner, Claudine Manach, Sandrine Thuret, Cecilia Samieri, Cristina Andres-Lacueva
Summary: This study reveals that fatty acids and related pathways are impaired in cognitive decline and dementia, and the relationship is dependent on the complex inter-relationships between the ApoE-e4 genotype and sex. Understanding this relationship is crucial for developing personalized therapeutic approaches for cognitive decline.
ALZHEIMERS RESEARCH & THERAPY
(2022)
Article
Environmental Sciences
Jeanne Duchesne, Laure-Anne Gutierrez, Isabelle Carriere, Thibault Mura, Jie Chen, Danielle Vienneau, Kees de Hoogh, Catherine Helmer, Benedicte Jacquemin, Claudine Berr, Marion Mortamais
Summary: This study found a link between higher exposure to PM2.5 and accelerated decline in global cognition in a large population-based cohort of French elderly individuals. No significant associations were detected for other pollutants or specific cognitive domains.
ENVIRONMENT INTERNATIONAL
(2022)
Letter
Clinical Neurology
Aline Thomas, Cecilia Samieri
Article
Public, Environmental & Occupational Health
Helene Jacqmin-Gadda, Viviane Philipps, Florian Guillet, Christophe Tzourio, Catherine Helmer, Pierre Joly
Summary: The prevalence and societal burden of dementia is expected to increase due to aging population. This study evaluates the potential impact of intervention scenarios targeting dementia risk factors on dementia burden. Micro-simulations are used to estimate the changes in dementia burden in France in 2040. The results show that targeting hypertension, diabetes, and physical inactivity could decrease dementia prevalence and increase life expectancy without dementia.
EUROPEAN JOURNAL OF EPIDEMIOLOGY
(2023)
Article
Psychiatry
Marie Alexandra Albaret, Julien Textoris, Bastien Dalzon, Jeremy Lambert, Morgane Linard, Catherine Helmer, Sabine Hacot, Sandra E. Ghayad, Martial Ferreol, Hichem C. Mertani, Jean-Jacques Diaz
Summary: Many studies suggest a potential link between Alzheimer's disease and HSV-1 infection, but the molecular mechanisms behind this process are not yet fully understood.
TRANSLATIONAL PSYCHIATRY
(2023)
Article
Environmental Sciences
Laure Gayraud, Marion Mortamais, Cedric Schweitzer, Kees de Hoogh, Audrey Cougnard-Gregoire, Jean-Francois Korobelnik, Marie-Noelle Delyfer, Marie-Benedicte Rougier, Karen Leffondre, Catherine Helmer, Danielle Vienneau, Claudine Berr, Cecile Delcourt
Summary: Chronic exposure to air pollution, particularly fine particulate matter (PM2.5) and black carbon (BC), is associated with faster thinning of the retinal nerve fiber layer (RNFL) in individuals with glaucoma. This study highlights the importance of considering air pollution as a potential risk factor for neurodegenerative diseases.
ENVIRONMENTAL RESEARCH
(2023)
Article
Neurosciences
Sara Cristina Lima Reboucas, Fabrice Crivello, Ami Tsuchida, Christophe Tzourio, Cedric Schweitzer, Jean-Francois Korobelnik, Cecile Delcourt, Catherine Helmer
Summary: The retina may serve as a window for viewing brain structures, as there are similarities between the two. This study found significant associations between retinal nerve fiber layers and brain MRI parameters, suggesting that retinal layers may reflect brain structures. Further studies are needed to confirm these findings in young subjects.
HUMAN BRAIN MAPPING
(2023)