Journal
INTERNATIONAL JOURNAL FOR PARASITOLOGY
Volume 43, Issue 11, Pages 875-877Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.ijpara.2013.06.008
Keywords
Echinococcus granulosus; G6 genotype; Brain; Human; Echinococcus cyst; Echinococcosis
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Funding
- Shiraz University of Medical Sciences, Iran [4987]
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The present study investigates the molecular characteristics of cerebral Echinococcus cysts. A total of 10 specimens of cerebral Echinococcus cysts, including six formalin-fixed paraffin blocks and four intact cerebral cysts, were used for this study. The target DNA was successfully amplified from eight samples and sequenced. BLAST analysis indicated that sequenced isolates belong to the Echinococcus gramilosus (G6) genotype. All of the eight sampled brain cysts belonged to the G6 genotype, while all of the eight liver cysts belonged to G1. This is a strong indication that G6 has a higher affinity for the human brain than G1. (C) 2013 Australian Society for Parasitology Inc. Published by Elsevier Ltd. All rights reserved.
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