Journal
INTERNATIONAL JOURNAL FOR NUMERICAL METHODS IN BIOMEDICAL ENGINEERING
Volume 28, Issue 6-7, Pages 626-641Publisher
WILEY
DOI: 10.1002/cnm.1466
Keywords
aortic valve; pulmonary valve; mitral valve; tricuspid valve; venous valve; stenosis; regurgitation; pulmonary hypertension
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Funding
- National Health and Medical Research Council of Australia
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Lumped parameter and one-dimensional models of the cardiovascular system generally employ ideal cardiac and/or venous valves that open and close instantaneously. However, under normal or pathological conditions, valves can exhibit complex motions that are mainly determined by the instantaneous difference between upstream and downstream pressures. We present a simple valve model that predicts valve motion on the basis of this pressure difference, and can be used to investigate not only valve pathology, but a wide range of cardiac and vascular factors that are likely to influence valve motion. Copyright (c) 2011 John Wiley & Sons, Ltd.
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