IL-21 and T follicular helper cells

Nasal Anti-CD3 Antibody Ameliorates Lupus by Inducing an IL-10-Secreting CD4+CD25-LAP+ Regulatory T Cell and Is Associated with Down-Regulation of IL-17+CD4+ICOS+CXCR5+ Follicular Helper T Cells

(2014) H. Y. Wu et al.   JOURNAL OF IMMUNOLOGY

Interleukin-21 Is Required for the Development of Type 1 Diabetes in NOD Mice

(2009) A. P.R. Sutherland et al.   DIABETES

Cytokine mediators of Th17 function

(2009) Rosanne Spolski et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Follicular Helper T Cells: Lineage and Location

(2009) Nicolas Fazilleau et al.   IMMUNITY

The Transcriptional Repressor Bcl-6 Directs T Follicular Helper Cell Lineage Commitment

(2009) Di Yu et al.   IMMUNITY

A T Cell-Dependent Mechanism for the Induction of Human Mucosal Homing Immunoglobulin A-Secreting Plasmablasts

(2009) Melissa Dullaers et al.   IMMUNITY

Follicular helper T cells are required for systemic autoimmunity

(2009) Michelle A. Linterman et al.   JOURNAL OF EXPERIMENTAL MEDICINE

T follicular helper cells differentiate from Th2 cells in response to helminth antigens

(2009) Arielle Glatman Zaretsky et al.   JOURNAL OF EXPERIMENTAL MEDICINE

IL-4–producing CD4+T cells in reactive lymph nodes during helminth infection are T follicular helper cells

(2009) Irah L. King et al.   JOURNAL OF EXPERIMENTAL MEDICINE

IL-21 Mediates Suppressive Effects via Its Induction of IL-10

(2009) R. Spolski et al.   JOURNAL OF IMMUNOLOGY

Cutting Edge: IL-27 Induces the Transcription Factor c-Maf, Cytokine IL-21, and the Costimulatory Receptor ICOS that Coordinately Act Together to Promote Differentiation of IL-10-Producing Tr1 Cells

(2009) C. Pot et al.   JOURNAL OF IMMUNOLOGY

Cytokine-secreting follicular T cells shape the antibody repertoire

(2009) R Lee Reinhardt et al.   NATURE IMMUNOLOGY

A critical role for IL-21 receptor signaling in the pathogenesis of systemic lupus erythematosus in BXSB-Yaa mice

(2009) J. A. Bubier et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Preferential Generation of Follicular B Helper T Cells from Foxp3+ T Cells in Gut Peyer's Patches

(2009) M. Tsuji et al.   SCIENCE

Bcl6 and Blimp-1 Are Reciprocal and Antagonistic Regulators of T Follicular Helper Cell Differentiation

(2009) R. J. Johnston et al.   SCIENCE

Bcl6 Mediates the Development of T Follicular Helper Cells

(2009) R. I. Nurieva et al.   SCIENCE

Regulation and Functions of Blimp-1 in T and B Lymphocytes

(2008) Gislâine Martins et al.   Annual Review of Immunology

T Follicular Helper (TFH) Cells in Normal and Dysregulated Immune Responses

(2008) Cecile King et al.   Annual Review of Immunology

Interleukin-6/STAT3 signaling regulates the ability of naive T cells to acquire B-cell help capacities

(2008) F. Eddahri et al.   BLOOD

CD4 T cells: fates, functions, and faults

(2008) J. Zhu et al.   BLOOD

A Fundamental Role for Interleukin-21 in the Generation of T Follicular Helper Cells

(2008) Alexis Vogelzang et al.   IMMUNITY

Generation of T Follicular Helper Cells Is Mediated by Interleukin-21 but Independent of T Helper 1, 2, or 17 Cell Lineages

(2008) Roza I. Nurieva et al.   IMMUNITY

ICOS-dependent extrafollicular helper T cells elicit IgG production via IL-21 in systemic autoimmunity

(2008) Jared M. Odegard et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The costimulatory molecule ICOS regulates the expression of c-Maf and IL-21 in the development of follicular T helper cells and TH-17 cells

(2008) Aurelie T Bauquet et al.   NATURE IMMUNOLOGY

IL-21 signaling is critical for the development of type I diabetes in the NOD mouse

(2008) R. Spolski et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Interleukin-21: Basic Biology and Implications for Cancer and Autoimmunity

(2007) Rosanne Spolski et al.   Annual Review of Immunology