Review
Medicine, General & Internal
Mohamad Swaikat, Ignacio Faus-Matoses, Alvaro Zubizarreta-Macho, Israa Ashkar, Vicente Faus-Matoses, Carlos Bellot-Arcis, Jose Enrique Iranzo-Cortes, Jose Maria Montiel-Company
Summary: A systematic review found that regenerative endodontic treatment (RET) showed high survival and success rates in treating traumatized necrotic immature permanent teeth. However, the impact of trauma on the prognosis of RET remains uncertain. Further research is needed to evaluate root maturation using 3-dimensional radiographic evaluations in traumatized teeth, and high-level clinical studies comparing RET with apexification are necessary.
JOURNAL OF CLINICAL MEDICINE
(2023)
Review
Chemistry, Physical
Pantaleo Scelza, Fabiano Goncalves, Isleine Caldas, Fernanda Nunes, Emanuelle Stellet Lourenco, Sandro Tavares, Marcela Magno, Andrea Pintor, Pietro Montemezzi, Emanuele Di Edoardo, Carlos Fernando de Almeida Barros Mourao, Gutemberg Alves, Miriam Zaccaro Scelza
Summary: The study found that Regenerative Endodontic Procedures (REP) showed a high success rate in treating mature teeth with necrotic pulp, reducing periapical lesions and restoring sensitivity. The success levels were similar to those reported for immature teeth, with very low certainty of evidence.
Review
Dentistry, Oral Surgery & Medicine
Emilio Carlos Sponchiado-Junior, Walbert de Andrade Vieira, Marcos Frozoni, Fernando Jose Herkrath, Adriana de-Jesus-Soares
Summary: The study found that the methodological quality of clinical trials in regenerative endodontics was low, with moderate to high risk of bias. Most articles complied with the CONSORT guidelines, but there is still room for improvement.
JOURNAL OF ENDODONTICS
(2021)
Article
Chemistry, Multidisciplinary
Benjamin Haarmann, Wadim Leontiev, Eva Magni, Sebastian Kuhl, Dorothea Dagassan-Berndt, Roland Weiger, Thomas Connert
Summary: The purpose of this ex vivo study was to determine the accuracy of template-based guided endodontics for access cavity preparation and root canal detection in posterior teeth. A total of 135 main root canals were detected utilizing guided endodontics, with a mean angle deviation of 1.4 degrees and mean deviations at the tip and base of the bur ranging from 0.24-0.31 mm and 0.26-0.29 mm, respectively. This study demonstrated that guided endodontics is an accurate and predictable method for endodontic access cavity preparation in posterior teeth.
APPLIED SCIENCES-BASEL
(2023)
Article
Dentistry, Oral Surgery & Medicine
Anmar Janabi, Patricia A. Tordik, Ina L. Griffin, Behzad Mostoufi, Jeffey B. Price, Priya Chand, Frederico C. Martinho
Summary: The study compared the accuracy and efficiency of the DNS and FH techniques in removing fiber posts from root canal-treated teeth, with results showing that the DNS group had smaller global coronal and apical deviations, angular deflection, shorter operation time, and less volumetric loss than the FH group.
JOURNAL OF ENDODONTICS
(2021)
Article
Dentistry, Oral Surgery & Medicine
Caroline Loureiro, Marilia Afonso Rabelo Buzalaf, Talita Mendes Oliveira Ventura, Vinicius Taioqui Pela, Gladiston William Lobo Rodrigues, Julia Guerra Andrade, Juliano Pelim Pessan, Rogerio Castilho Jacinto
Summary: This study quantitatively and qualitatively analyzed the proteomic profile of teeth with acute apical abscesses (AAA) and chronic apical periodontitis (CAP). The results showed significant differences in protein expression between the two groups, with AAA group mainly associated with immune inflammatory response and oxidative stress response, and CAP group mainly associated with DNA/RNA regulation and repair, and structural function.
CLINICAL ORAL INVESTIGATIONS
(2023)
Article
Multidisciplinary Sciences
Namita Gandhi, Nimisha Shah, Dian Agustin Wahjuningrum, Sweetly Purnomo, Riana Nooshian, Suraj Arora, Ajinkya M. Pawar
Summary: This study conducted a clinical trial on adult patients with symptomatic irreversible pulpitis in mandibular teeth and found that preheated and buffered local anesthetics are more effective in reducing intraoperative discomfort compared to conventional local anesthetics.
Review
Dentistry, Oral Surgery & Medicine
Filipe Colombo Vitali, Ana Cristina Andrada, Helhen Cristina da Luz Cardoso, Gesner Francisco Xavier-Junior, Cleonice da Silveira Teixeira, Loise Pedrosa Salles, Erica Negrini Lia, Carla Massignan
Summary: This study evaluated the safety and efficacy of natural products for endodontic therapy in primary teeth and found insufficient evidence to support their clinical application. While most studies showed similar efficacy between natural products and control groups, there are concerns about methodological biases and the safety and efficacy of natural products.
CLINICAL ORAL INVESTIGATIONS
(2022)
Article
Education & Educational Research
Sareh Said Yekta-Michael, Christoph Maria Faerber, Alexander Heinzel
Summary: The study evaluated new radiopaque artificial root canal treatment models designed for undergraduate students, showing positive evaluations from both students and demonstrators with improvements in pulp anatomy and ability to flare root canals after modifications. The results suggest that these models could be a promising alternative or additional tool for dental education, highlighting the potential for enhancing teaching methods.
BMC MEDICAL EDUCATION
(2021)
Article
Dentistry, Oral Surgery & Medicine
James Dudley
Summary: This study compared the reasons for selecting and the direct experiences of students with artificial teeth used in two consecutive pre-clinical fixed prosthodontics post-core technique teaching programs. The use of artificial teeth was driven by difficulty in sourcing appropriate natural teeth, and students reported ease of use as the dominant positive experience. However, the unrealistic simulation of natural teeth and different surface texture when cutting were seen as negative aspects. Overall, artificial teeth were considered to provide an appropriate and realistic simulation compared with extracted natural teeth and were easier to source.
EUROPEAN JOURNAL OF DENTAL EDUCATION
(2023)
Review
Dentistry, Oral Surgery & Medicine
Lucas Peixoto de Araujo, Leandro Bueno Gobbo, Tamares Andrade da Silva, Wellington Luiz de Oliveira da Rosa, Jose Flavio Affonso de Almeida, Brenda P. F. A. Gomes, Caio Cezar Randi Ferraz
Summary: The aim of this study was to evaluate the efficacy of supplementary photodynamic therapy (PDT) on primary tooth pulpectomy through a systematic review. Four studies met the inclusion criteria, but no significant conclusions could be drawn due to the moderate-to-low certainty of the available evidence.
INTERNATIONAL JOURNAL OF PAEDIATRIC DENTISTRY
(2023)
Article
Dentistry, Oral Surgery & Medicine
Xijun Jiang, He Liu, Chufang Peng
Summary: The study found that the use of a collagen membrane (Bio-Gide) could promote an increase in dentin wall thickness in the middle one-third of the root in immature teeth, and it had no significant effect on the subsequent type of root development.
INTERNATIONAL JOURNAL OF PAEDIATRIC DENTISTRY
(2022)
Review
Dentistry, Oral Surgery & Medicine
Fahad Umer, Saqib Habib
Summary: This scoping review analyzed the use of artificial intelligence (AI) algorithms and models in endodontics. Most studies used neural networks, particularly convolutional neural networks. The AI models showed acceptable performance, achieving accuracy rates above 90% in diagnostic tasks. However, there were irregularities in the reporting of AI-related research. The endodontic community should implement recommended guidelines to improve the scientific rigor of AI research.
JOURNAL OF ENDODONTICS
(2022)
Review
Chemistry, Multidisciplinary
Justyna Zbanska, Katarzyna Herman, Piotr Kuropka, Maciej Dobrzynski
Summary: Regenerative endodontic procedure (REP) is an alternative treatment for immature permanent teeth with incomplete root development, aiming to promote angiogenesis, reinnervation, and further root formation. The success of REP depends on the condition of the tooth and the cooperation of the patient.
APPLIED SCIENCES-BASEL
(2021)
Article
Dentistry, Oral Surgery & Medicine
Hakan Arslan, Ezgi Doganay Yildiz, Huseyin Sinan Topcuoglu, Ebru Tepecik, Gizem Tas
Summary: The study found that calcium hydroxide mixed with lidocaine HCl can significantly reduce postoperative pain in patients with irreversible pulpitis and symptomatic apical periodontitis. The mixture was more effective than calcium hydroxide mixed with saline in reducing pain during days 1 to 4 postoperatively.
CLINICAL ORAL INVESTIGATIONS
(2021)
Article
Dentistry, Oral Surgery & Medicine
Ralf-Joachim Kohal, Christopher von Schierholz, Julian Nold, Benedikt C. C. Spies, Erik Adolfsson, Kirstin Vach, Felix Burkhardt
Summary: The objective of this study was to investigate the fracture strength and potential phase transformation of an injection-molded two-piece zirconia implant restored with a zirconia abutment after loading and/or aging. The results showed that dynamic loading and the combination of loading and aging reduced the fracture strength of the implant abutment combination. Hydrothermal treatment caused a shallow transformation zone which had no influence on the fracture strength.
CLINICAL ORAL IMPLANTS RESEARCH
(2023)
Article
Infectious Diseases
Ali Al-Ahmad, Michael Haendel, Markus Joerg Altenburger, Lamprini Karygianni, Elmar Hellwig, Karl Thomas Wrbas, Kirstin Vach, Christian Tennert
Summary: This study evaluated the initial microbial adhesion of oral microorganisms on Biodentine, MTA, and AH Plus in vivo. The results showed that Biodentine had significantly lower aerobic CFUs compared to MTA and AH Plus. DAPI staining revealed that Biodentine had the lowest amount of adherent microorganisms, while MTA had the highest. Biodentine demonstrated antimicrobial effectiveness similar to MTA.
Article
Engineering, Biomedical
Ralf-Joachim Kohal, Kirstin Vach, Frank Butz, Benedikt Christopher Spies, Sebastian Berthold Maximilian Patzelt, Felix Burkhardt
Summary: The study investigated the clinical and radiological outcome of one-piece zirconia oral implants supporting three-unit fixed dental prostheses after three years. 54 implants were placed in 27 patients through a one-stage surgery and immediate provisionalization. Standardized radiographs were taken at different time points to evaluate bone loss and soft-tissue parameters. The zirconia implants exhibited a cumulative survival rate of 98.1% after three years, with a mean marginal bone loss of 2.16 mm. However, high peri-implantitis incidence and low implant success rate were observed, indicating a possible concern for long-term stability.
JOURNAL OF FUNCTIONAL BIOMATERIALS
(2023)
Article
Dentistry, Oral Surgery & Medicine
Florian Kernen, Dominik Braendle, Oliver Wagendorf, Mario Recca, Juergen Mehrhof, Kirstin Vach, Susanne Nahles, Katja Nelson, Tabea Fluegge
Summary: This study evaluated the accuracy of an intraoral scan aid for scanning multiple implants in the edentulous arch. By comparing the scans of 87 implants in 22 patients, it was found that the scan aid significantly improved scanning accuracy and success rate.
CLINICAL ORAL IMPLANTS RESEARCH
(2023)
Article
Dentistry, Oral Surgery & Medicine
Laura Kleinvogel, Gregor Wemken, Cosima Reidelbach, Manuel Garcia-Kaeufer, Kirstin Vach, Elmar Hellwig, Benedikt C. Spies, Olga Polydorou
Summary: This study developed a novel in-vitro method to evaluate the release of wear particles from dental restorative materials in the oral cavity. The method involved immersing the specimens and subjecting them to wear tests using a dual-axis chewing simulator. The study found that there were differences in particle size and volume loss between different materials. This method is capable of accurately detecting nanoscale particles.
Article
Dentistry, Oral Surgery & Medicine
Severin Rothlauf, Stefano Pieralli, Christian Wesemann, Felix Burkhardt, Kirstin Vach, Florian Kernen, Benedikt Christopher Spies
Summary: This study evaluated the influence of planning software and design of surgical templates on the accuracy and precision of static computer assisted implant surgery. Virtual positioning of two adjacent oral implants using two planning software was performed and surgical guides were fabricated using material extrusion. The installation of implants using these guides showed clinically acceptable deviations.
JOURNAL OF DENTISTRY
(2023)
Review
Nutrition & Dietetics
Johan Peter Woelber, Katharina Reichenbaecher, Tara Gross, Kirstin Vach, Petra Ratka-Krueger, Valentin Bartha
Summary: The aim of this study was to review the influence of dietary and nutraceutical interventions as an adjunct to non-surgical periodontal therapy. A literature search identified 14 relevant clinical trials out of 20. The results showed positive effects on periodontal parameters for vitamin E, chicory extract, juice powder, green tea, and oolong tea, while effects were more inconsistent for lycopene, folate, omega-3 fatty acids, and vitamin D. The study suggests that supplemental intake of micronutrients, omega-3 fatty acids, green/oolong tea, and polyphenols and flavonoids could be beneficial for periodontal health.
Article
Engineering, Biomedical
Ralf-Joachim Kohal, Anja Trinkner, Felix Burkhardt, Sebastian Berthold Maximilian Patzelt, Kirstin Vach, Monika Kuster, Anze Abram, Andraz Kocjan, Julian Nold
Summary: The aim of this study was to evaluate the long-term stability of one-piece diameter reduced zirconia oral implants under loading and artificial aging. The results showed that dynamic loading, hydrothermal aging, and the combination of loading and aging did not significantly affect the stability of the implants. The implant system was able to resist physiological chewing forces and maintain stability over a long service period.
JOURNAL OF FUNCTIONAL BIOMATERIALS
(2023)
Article
Biotechnology & Applied Microbiology
Tara Gross, Martin Philipp Dieterle, Kirstin Vach, Markus Joerg Altenburger, Elmar Hellwig, Susanne Proksch
Summary: This study investigated the differentiation of dental pulp stem cells (DPSCs) towards soft tissue using extracellular elasticity. DPSCs cultured on substrates with a low elasticity of 1.5 kPa showed a soft tissue-like phenotype and gene expression, while cells cultured on substrates with a higher elasticity of 28 kPa exhibited a differentiation signature resembling hard tissues. Cells cultured on substrates with an intermediate elasticity of 15 kPa showed the highest cytokine expression, suggesting their potential role as trophic mediators.
BIOENGINEERING-BASEL
(2023)
Letter
Dentistry, Oral Surgery & Medicine
W. Vach, K. Vach, C. Ganss
Article
Engineering, Biomedical
Babak Saravi, Julia Ilbertz, Kirstin Vach, Ralf J. Kohal, Sebastian B. M. Patzelt
Summary: Computerized optical impression making (COIM) is a rising trend in dental prosthetics for removable dentures, but its accuracy compared with traditional impression-making techniques remains uncertain. A study evaluating the accuracy of COIM in partially edentulous jaws found that it captured dental hard tissue more accurately than mucosal areas, likely due to software algorithms filtering out mobile tissues. Clinically, caution is needed when using COIM for prosthetics involving mucosal tissues as deviations could compromise the fit and longevity.
JOURNAL OF FUNCTIONAL BIOMATERIALS
(2023)
Article
Dentistry, Oral Surgery & Medicine
David Steybe, Philipp Poxleitner, Marc C. Metzger, Rene Rothweiler, Juergen Beck, Jakob Straehle, Kirstin Vach, Andreas Weber, Kathrin Enderle-Ammour, Martin Werner, Rainer Schmelzeisen, Peter Bronsert
Summary: Stimulated Raman histology (SRH) is a highly accurate method for diagnosing neoplastic and non-neoplastic tissues in patients with oral squamous cell carcinoma (OSCC), compared to H&E-stained frozen sections.
CLINICAL ORAL INVESTIGATIONS
(2023)
Article
Dentistry, Oral Surgery & Medicine
Cosima Reidelbach, Michael Swoboda, Mathias Spraul, Kirstin Vach, Sebastian B. M. Patzelt, Elmar Hellwig, Olga Polydorou
Summary: The aim of this study was to evaluate the effects of erosion and abrasion on different dental materials. The results showed that resin-matrix ceramics had lower surface wear compared to feldspar ceramics, suggesting better restoration longevity.
EUROPEAN JOURNAL OF ORAL SCIENCES
(2023)
Article
Chemistry, Physical
Aimen Bagegni, Justus Borchers, Samuel Beisel, Sebastian B. M. Patzelt, Kirstin Vach, Ralf Kohal
Summary: This study evaluated the effects of different luting agents on the bonding between zirconium dioxide crowns and titanium bonding bases. The results showed that most luting agents were suitable for cementation of zirconium dioxide crowns, meeting the recommended debonding force value.
Article
Nutrition & Dietetics
Mia Klein, Ali Al-Ahmad, Marie Follo, Elmar Hellwig, Kirstin Vach, Sigrun Chrubasik-Hausmann
Summary: This study demonstrates that antimicrobial photodynamic treatment with visible light plus water-filtered infrared-A irradiation and lingonberry extract has potent antimicrobial activity against various bacteria related to oral health.