Article
Dentistry, Oral Surgery & Medicine
B. Latifi-Xhemajli, T. Kutllovci, A. Begzati, A. Rexhepi, D. Ahmeti
Summary: This study compares the prevalence and distribution of mutans streptococci (SM) in high caries-risk children after 24 months of exposure to 25% xylitol toothpaste. The results show that using xylitol toothpaste and brushing habit can reduce SM contamination and potentially prevent caries.
EUROPEAN JOURNAL OF PAEDIATRIC DENTISTRY
(2023)
Review
Biochemistry & Molecular Biology
Virag Rona, Bulcsu Bencze, Kata Kelemen, Daniel Vegh, Reka Toth, Tamas Koi, Peter Hegyi, Gabor Varga, Noemi Katinka Rozsa, Zoltan Geczi
Summary: This study conducted a meta-analysis and systematic review to investigate the efficacy of chitosan-containing chewing gums and their inhibitory effects on Streptococcus mutans. The results showed that chitosan reduced the number of bacteria, but further studies are needed.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Dentistry, Oral Surgery & Medicine
Craig S. Miller, Robert J. Danaher, Sree Kirakodu, Charles R. Carlson, Russell J. Mumper
Summary: Chewing gum containing freeze-dried blackberry powder can significantly reduce the quantity of various oral bacteria in saliva, including major oral bacterial strains. Regardless of the CG or BG group, S. sanguinis and A. naeslundii were the predominant bacteria adherent to enamel after gum chewing, with S. mutans representing only a small percentage of the total bacteria on enamel.
ARCHIVES OF ORAL BIOLOGY
(2022)
Article
Biochemistry & Molecular Biology
Igor Zen, Alberto Carlos Botazzo Delbem, Tamires Passadori Martins, Leonardo Antonio de Morais, Caio Sampaio, Thayse Yumi Hosida, Douglas Roberto Monteiro, Juliano Pelim Pessan
Summary: This study assessed the effects of solutions containing fluoride, sodium trimetaphosphate, xylitol, and erythritol on dual-species biofilms of Streptococcus mutans and Candida albicans. The results showed that fluoride and trimetaphosphate were the main active ingredients and had a synergistic effect on most variables. The polyols had modest effects on their own but, when combined with fluoride and trimetaphosphate, resulted in a greater reduction in S. mutans and biofilm biomass.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Biochemistry & Molecular Biology
Fighan Jalal Hussein, Sazan Sherdl Saleem, Khalid Abdulaziz Merdad
Summary: This study used the Cariogram software program and real-time PCR analysis to study the association between pregnancy and dental caries, as well as the levels of Streptococcus mutans and lactobacillus in saliva. The results showed a significant but weak positive correlation between the amount of these bacteria and caries risk categories. Pregnant women had a higher proportion of lactobacillus and lower levels of Streptococcus mutans compared to non-pregnant women. These bacteria play an important role in the development of dental caries, especially in pregnant women.
CELLULAR AND MOLECULAR BIOLOGY
(2023)
Article
Dentistry, Oral Surgery & Medicine
Sili Han, Yuki Abiko, Jumpei Washio, Yufang Luo, Linglin Zhang, Nobuhiro Takahashi
Summary: The study found that EGCG has short-term antibacterial effects on caries-associated streptococci, including inhibition of bacterial growth and acid production, and promotion of bacterial aggregation.
Article
Dentistry, Oral Surgery & Medicine
Stefano Lai, Peter Lingstrom, Maria Grazia Cagetti, Fabio Cocco, Gianfranco Meloni, Maria Antonietta Arrica, Guglielmo Campus
Summary: This study evaluated the short-term effects of Lactobacillus brevis CD2 lozenges vs placebo on variables related to caries and gingivitis in type 1 diabetic children. The results showed that the probiotic lozenges reduced bacterial density and increased pH levels, while also decreasing bleeding scores in both groups, with a statistically significant lower bleeding score in the probiotic group at 60 days.
CLINICAL ORAL INVESTIGATIONS
(2021)
Article
Chemistry, Multidisciplinary
Amit Wolfoviz-Zilberman, Yael Houri-Haddad, Nurit Beyth
Summary: In vitro and in vivo models were compared in this study to evaluate anti-caries modalities for prevention and treatment. The developed in vitro caries model demonstrated rapid caries development within 5 days, especially in the depth of occlusal fissures in the control group. This model may provide a novel animal-sparing approach for caries disease studies and assessing the efficacy of antibacterial dental materials.
APPLIED SCIENCES-BASEL
(2021)
Review
Dentistry, Oral Surgery & Medicine
Shweta Sharda, Arpit Gupta, Ashima Goyal, Krishan Gauba
Summary: The combination therapy of CPP-ACP-TF showed superior remineralization and antibacterial effects compared to TF mono-therapy, while xylitol provided additional benefits in preventing caries. However, the low certainty of evidence highlights the necessity for more high-quality trials to confirm these findings.
ACTA ODONTOLOGICA SCANDINAVICA
(2021)
Article
Multidisciplinary Sciences
Isamu Kado, Ryo Kunimatsu, Yuki Yoshimi, Cynthia Concepcion Medina, Sakura Yamada, Kotaro Tanimoto
Summary: Saliva plays a crucial role in masticatory function and caries prevention. Studies on saliva properties have shown that males have significantly higher saliva flow rate, pH, and buffering capacity than females, although the Streptococcus mutans score is higher in females and positively correlates with saliva flow rate.
SCIENTIFIC REPORTS
(2021)
Article
Chemistry, Physical
Kyungsun Kim, Jeong Nam Kim, Bum-Soon Lim, Sug-Joon Ahn
Summary: The study found that UDMA promotes the adhesion, extracellular polysaccharide synthesis, and biofilm formation of S. mutans, while reducing its acid tolerance but enhancing its oxidative stress tolerance. This may favor the early stage of biofilm development.
Article
Dentistry, Oral Surgery & Medicine
Andrei C. Ionescu, Sebastian Hahnel, Paolo Delvecchio, Nicoleta Ilie, Marioara Moldovan, Vanessa Zambelli, Giacomo Bellani, Eugenio Brambilla
Summary: This study compared the efficacy of two in vitro microbiological models, open and closed systems, for obtaining secondary caries. The results showed that the open system bioreactor produced lesions with significantly higher overall demineralization depths. However, demineralization depths at a 1.0 mm distance from the restoration margins showed no difference between open and closed systems or materials.
JOURNAL OF DENTISTRY
(2022)
Article
Immunology
Kristian Havsed, Malin Stensson, Henrik Jansson, Miguel Carda-Dieguez, Anders Pedersen, Jessica Neilands, Gunnel Svensater, Alex Mira
Summary: This study identified specific bacterial species and metabolites in dental plaque samples associated with caries risk, suggesting that caries risk assessment should consider the functional adaptation and metabolic output of bacteria.
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY
(2021)
Article
Microbiology
Alma Catala-Valentin, Joshua N. Bernard, Matthew Caldwell, Jessica Maxson, Sean D. Moore, Claudia D. Andl
Summary: The study found that exposure to e-cigarette aerosols inhibits the growth of two commensal streptococci in the oral cavity while enhancing biofilm formation, hydrophobicity, and attachment for the pathogen S. mutans. These results suggest that vaping could create a niche for opportunistic bacteria like S. mutans to colonize the oral cavity and affect oral health.
MICROBIOLOGY SPECTRUM
(2022)
Article
Microbiology
Greete Maasi, Jelena Stsepetova, Merike Joesaar, Jana Olak, Reet Maendar
Summary: This study compared the virulence genes of two common mutans streptococci species (S. mutans and S. sobrinus) and correlated them with clinical data. The results showed that S. mutans strains had more virulence genes and certain genes showed correlation with each other. S. sobrinus strains lacked some important virulence genes. The study also found a positive association between certain adhesion-related genes and the amount of mutans streptococci in saliva. These findings contribute to a better understanding of the pathogenic mechanisms of mutans streptococci.
MICROBIOLOGY RESEARCH
(2022)
