Article
Biotechnology & Applied Microbiology
Mahnaz Barmshuri, Bahman Kholdebarin, Saber Sadeghi
Summary: Using MTT and Comet assay techniques in algal studies can provide researchers with prominent features about photosynthesis and genomes. The reduction of MTT in unicellular algal cells mostly reflects the activity of chloroplasts. The application of MTT and Comet assay techniques is recommended for monitoring environmental hazards.
ALGAL RESEARCH-BIOMASS BIOFUELS AND BIOPRODUCTS
(2023)
Article
Medicine, Research & Experimental
Alex Zohmachhuana, Malsawmdawngliana, F. Lalnunmawia, Vabeiryureilai Mathipi, K. Lalrinzuali, N. Senthil Kumar
Summary: The aim of this study was to evaluate the phytochemical content, antioxidant and anti-cancer activities of different parts of Curcuma aeruginosa Roxb. The methanol extracts from C. aeruginosa showed cytotoxicity against lung adenocarcinoma and cervical cancer cells, induced DNA damage, and up-regulated caspase activity. Additionally, bioactive compounds identified from the plant have been found to possess anti-cancer properties.
BIOMEDICINE & PHARMACOTHERAPY
(2022)
Article
Plant Sciences
Hatice Alkan, Ibrahim Hakki Cigerci, Muhammad Muddassir Ali, Omer Hazman, Recep Liman, Florica Cola, Elena Bonciu
Summary: This study evaluated the cytotoxic and genotoxic effects of biosynthesized silver nanoparticles on breast cancer and umbilical vein endothelial cells. The results showed that the synthesized silver nanoparticles exhibited cytotoxic and genotoxic effects on breast cancer cells, but had no significant effects on normal cells.
Article
Food Science & Technology
Merve Bacanli, Ozgur Esim, Hakan Erdogan, Meral Sarper, Onur Erdem, Yalcin Ozkan
Summary: This study evaluated the cytotoxicity and genotoxicity of paclitaxel nanoencapsulated with PLGA in human neuroblastoma cells. Results showed that PLGA nanoparticles can be considered as a biocompatible carrier system for drug delivery and might be a promising agent against neuroblastoma.
FOOD AND CHEMICAL TOXICOLOGY
(2021)
Article
Food Science & Technology
Beibei Li, Jiaqi Duan, Jie Ren, Frederic Francis, Guangyue Li
Summary: In this study, two DON-degrading bacterial strains, Bacillus sp. HN117 and Bacillus sp. N22, were isolated and characterized. Both strains were able to efficiently degrade DON in a wide range of temperatures and concentrations. The degradation products included a new isomer and potential low-toxic derivatives. These strains have the potential to be used as biodegrading agents to control DON contamination in food and feed industries.
Article
Environmental Sciences
Duantao Cao, Shuhong He, Xin Li, Lihong Shi, Feiyan Wang, Sumei Yu, Shiji Xu, Chao Ju, Hua Fang, Yunlong Yu
Summary: The bacterial strain Arthrobacter sp. C2 was isolated for atrazine degradation, showing degradation rates of 0.34, 1.94, and 18.64 mg/L/d at different concentrations. The optimal conditions for degradation were at 30°C and pH 7.0-9.0, and a metabolic pathway for atrazine degradation was proposed. The introduction of strain C2 into soil can enhance atrazine degradation and eliminate its toxic effects on wheat growth.
Article
Agricultural Engineering
Shanling Gan, Yujia Li, Xiumin Zhang, Lirong Luo, Xinyi Xu, Jiaming Jiang, Yu Huo, Changhua Shang
Summary: In this study, distiller's grains were pretreated and detoxified to improve the production of tetramethylpyrazine. The optimal conditions for detoxification resulted in a significant increase in tetramethylpyrazine yield. This research provides a viable method for tetramethylpyrazine production from distiller's grains.
INDUSTRIAL CROPS AND PRODUCTS
(2023)
Article
Environmental Sciences
Ke Meng, Ying Teng, Wenjie Ren, Beibei Wang, Violette Geissen
Summary: The degradation performance of commercially available biodegradable plastics (BDPs) and the response of soil microbial communities to biodegradation are still unclear. In this study, a commercial BDP product (made from starch, polylactic acid (PLA), and polybutylene adipate terephthalate (PBAT)) was investigated for its degradation characteristics in different soils over a period of 360 days. Weight loss reached 42.0 +/- 1.2% to 48.0 +/- 2.2% in different soils after 360 days. The degradation of BDP followed two distinct stages, with the first stage characterized by major weight loss, drastic increase in soil dissolve organic carbon, and formation of distinct bacterial communities in the plastic surface soil. The second stage involved the slower degradation of remaining PLA and PBAT, accompanied by the gradual recovery of bacterial communities in the plastic surface soil. These findings highlight the importance of the degradation rate and soil bacterial dynamics in the performance of BDPs.
SCIENCE OF THE TOTAL ENVIRONMENT
(2023)
Article
Biotechnology & Applied Microbiology
Neha Sharma, Vinay Kumar, S. S. Maitra, Sivarama Krishna Lakkaboyana, Soontarapa Khantong
Summary: This study focuses on the biodegradation kinetics of DBP by Acinetobacter sp.33F in pristine agricultural soils and demonstrates its potential as a promising candidate for the removal of phthalate esters from contaminated agricultural sites.
ENVIRONMENTAL TECHNOLOGY & INNOVATION
(2021)
Article
Biochemistry & Molecular Biology
Walaa Alharbi, Iftekhar Hassan, Rais Ahmad Khan, Shazia Parveen, Khadijah H. Alharbi, Ibtisam I. Bin Sharfan, Ibrahim M. Alhazza, Hossam Ebaid, Ali Alsalme
Summary: Biocompatible tryptophan-derived copper and zinc complexes were designed, synthesized, and evaluated for potential anticancer activity in vitro and in vivo. The results demonstrated decent selectivity and regulation of oxidative stress pathways in cancer cells.
Article
Biochemistry & Molecular Biology
Amber M. Tavener, Megan C. Phelps, Richard L. Daniels
Summary: Anthracyclines show cytotoxic effects on GL261 glioma cells, inducing apoptosis in a dose-dependent manner; however, high concentrations may lead to cell necrosis. Results support further exploration of anthracyclines as potential compounds for improved GBM treatments.
MOLECULAR BIOLOGY REPORTS
(2021)
Article
Food Science & Technology
Mohamed Salama, Dina Mostafa Mohammed, Khaled Fahmy, Neima K. Al-Senosy, Naglaa M. Ebeed, Amr Farouk
Summary: Diacetyl is a common ingredient that adds a buttery flavor to baked goods and other food products. This study showed that diacetyl had a cytotoxic impact on human liver cells, leading to DNA damage, activation of apoptotic and necrosis mechanisms, disruption of the liver's oxidant/antioxidant balance, increased inflammatory cytokines, and histopathological changes. In-silico analysis suggested that diacetyl may interact with certain proteins, potentially resulting in upregulated gene expression.
FOOD AND CHEMICAL TOXICOLOGY
(2023)
Article
Biotechnology & Applied Microbiology
Yanning Tian, Guoqiang Zhao, Minggen Cheng, Luyao Lu, Hao Zhang, Xing Huang
Summary: In this study, a gene encoding a nitroreductase DnrA responsible for the reduction of nitro to amino groups was identified from Bacillus sp. Za strain. DnrA showed a broad substrate spectrum and could mitigate the growth inhibition effect on cucumber and sorghum through nitroreduction of diphenyl ether herbicides. Molecular docking analysis revealed the interaction mechanisms between diphenyl ether herbicides and DnrA. This research provides new genetic resources and insights into the microbial remediation of diphenyl ether herbicide-contaminated environments.
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
(2023)
Article
Agronomy
Kshitij Khatri, Gary Vallad, Natalia Peres, Johan Desaegaer, Homan Regmi, Nathan Boyd
Summary: The study demonstrates that metam-K can effectively control important pests in Florida plasticulture production systems, with Meloidogyne javanica being the most sensitive pest, while Geranium carolinianum and Medicago lupulina are the least sensitive weed species.
PEST MANAGEMENT SCIENCE
(2021)
Article
Biotechnology & Applied Microbiology
Wankui Jiang, Qinqin Gao, Lu Zhang, Yali Liu, Mingliang Zhang, Zhijian Ke, Yidong Zhou, Qing Hong
Summary: Strobilurin fungicides are widely used in agriculture, but their widespread application has negative effects on freshwater ecosystems. This study identified a strain capable of degrading strobilurin fungicides and a novel esterase gene, strH, which detoxifies these fungicides and relieves their inhibitory effects on algae growth.
APPLIED AND ENVIRONMENTAL MICROBIOLOGY
(2021)
Article
Agricultural Engineering
Mihir Tanay Das, Varaporn Budhraja, Monika Mishra, Indu Shekhar Thakur
BIORESOURCE TECHNOLOGY
(2012)
Article
Environmental Sciences
Mihir Tanay Das, Pooja Ghosh, Indu Shekhar Thakur
ENVIRONMENTAL POLLUTION
(2014)
Article
Environmental Sciences
Monika Mishra, Mihir Tanay Das, Indu Shekhar Thakur
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2014)
Article
Environmental Sciences
Pooja Ghosh, Mihir Tanay Das, Indu Shekhar Thakur
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2014)
Article
Biotechnology & Applied Microbiology
Swati Pooja Ghosh, Mihir Tanay Das, Indu Shekhar Thakur
INTERNATIONAL BIODETERIORATION & BIODEGRADATION
(2014)
Article
Biotechnology & Applied Microbiology
Umesh Chandra Naik, Mihir Tanay Das, Swati Sauran, Indu Shekhar Thakur
MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS
(2014)
Review
Engineering, Environmental
Mihir Tanay Das, Smita S. Kumar, Pooja Ghosh, Goldy Shah, Sandeep K. Malyan, Somvir Bajar, Indu Shekhar Thakur, Lakhveer Singh
Summary: Phthalates, used as plasticizers, pose potential risks to human health and the environment, leading to a growing concern in recent years. Researchers aim to understand the pollution status, sources, health impacts of phthalates, as well as develop technologies to mitigate the risks associated with phthalate contamination.
JOURNAL OF HAZARDOUS MATERIALS
(2021)
Article
Biology
Mihir Tanay Das, Manoj Kumar Singh, Indu Shekhar Thakur
INDIAN JOURNAL OF EXPERIMENTAL BIOLOGY
(2014)
Article
Biotechnology & Applied Microbiology
Shaofeng Zhou, Wenwen An, Cuifen Gan, Meiying Xu
Summary: Bacteria generate and release extracellular reactive oxygen species (eROS), which significantly contribute to the natural ROS pool and play a crucial role in metabolic interactions of bacteria with their environment. Understanding the behavior of eROS-generating bacteria and its environmental implications is of great importance in the cycling of biogeochemical elements, transformation of organic matter, and regulation of antibiotic resistance genes.
INTERNATIONAL BIODETERIORATION & BIODEGRADATION
(2024)
Article
Biotechnology & Applied Microbiology
Ji-Dong Gu, Tim Ford, Bryce Mitton, Ralph Mitchell
Summary: Plastics and microplastics are widely present and accumulating in the environment, leading to increasing public attention. In addition to packaging plastics, materials from industries such as electronics, space and aviation are also accumulating, but receiving less attention. The production of degradable and biodegradable plastics is seen as a way to reduce environmental impacts, but enhancing the non-degradability of functional polymers is also a feasible option. Microbial colonization and deterioration pose significant challenges to these materials.
INTERNATIONAL BIODETERIORATION & BIODEGRADATION
(2024)
Article
Biotechnology & Applied Microbiology
Justyna Bohacz, Michal Mozejko
Summary: This study evaluated the keratinolytic activity of 37 strains of Trichophyton ajelloi and found that pigmented strains isolated from loamy soil were more efficient in degrading native feather keratin, while non-pigmented strains isolated from chernozem showed better abilities. The keratinolytic activity increased over time, as evidenced by the increase in extracellular keratinase activity and release of soluble proteins and peptides. Protease activity peaked in the first 7 days and again on day 28 of culture. The release of ammonium and sulfate ions, associated with an increase in pH, reached its maximum on day 21. Three pigment-producing strains were among the most active in releasing large amounts of ammonium and sulfate ions. The biodegradation of feather waste by Trichophyton ajelloi strains can be used to produce fertilizers suitable for plants with high sulfur requirements.
INTERNATIONAL BIODETERIORATION & BIODEGRADATION
(2024)
Article
Biotechnology & Applied Microbiology
Joseph M. Suflita, Brenda J. Little
Summary: This article reviews the major achievements of the International Biodeterioration & Biodegradation Society (IBBS) on its 50th anniversary and provides recommendations for addressing new challenges and developments based on personal experiences.
INTERNATIONAL BIODETERIORATION & BIODEGRADATION
(2024)
Article
Biotechnology & Applied Microbiology
Zhenyan Lin, Tuo Jin, Xin Xu, Xiao Yin, Dan Zhang, Mengjiao Geng, Chunyu Pang, Gongwen Luo, Lizhi Xiong, Jianwei Peng, Jiangchi Fei
Summary: The incomplete recycle of residual mulch film (RMF) in recent years has led to an increase in plastic fragments in soil, posing a serious threat to the soil ecological environment. In this study, seven potential plastic-degrading microorganisms were screened and identified from film-mulched vegetable fields. The degradation ability experiments showed that both single strains and mixed strains demonstrated varying levels of degradation of RMF.
INTERNATIONAL BIODETERIORATION & BIODEGRADATION
(2024)
Article
Biotechnology & Applied Microbiology
Tiina Belt, Michael Altgen, Muhammad Awais, Martin Nopens, Lauri Rautkari
Summary: This study investigated the degradation of heat-treated wood by brown rot fungi and found that the decay increased the hygroscopicity of wood in the decaying state. Furthermore, it was observed that heat-treated samples were more susceptible to fungal decay compared to untreated samples, which may be related to the increase in moisture content.
INTERNATIONAL BIODETERIORATION & BIODEGRADATION
(2024)
Article
Biotechnology & Applied Microbiology
Marta Cicardi, Davide Bernasconi, Luca Martire, Linda Pastero, Giulia Caneva, Sergio E. Favero-Longo
Summary: This study investigated the phenomenon of Centimetric circular areas Uncolonized by Microbial Biofilms (CUMBs) on natural and heritage stone surfaces. The analysis revealed a compatibility in distribution and size between CUMBs and lichen thalli, suggesting a lichen origin for some CUMBs. Microscopic analysis also showed similar modifications in marble layers beneath CUMBs and lichens, indicating a possible alteration of stone properties by lichens.
INTERNATIONAL BIODETERIORATION & BIODEGRADATION
(2024)
