Journal
INTERNAL MEDICINE
Volume 49, Issue 23, Pages 2599-2603Publisher
JAPAN SOC INTERNAL MEDICINE
DOI: 10.2169/internalmedicine.49.3978
Keywords
Graves' disease; hyperthyroidism; Epstein-Barr virus; infectious mononucleosis; atypical cell; liver injury
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Although the etiology of Graves' disease is still not clear, it is generally suggested that environmental factors such as infections contribute to the development of Graves' disease. We report here three cases of Graves' disease which presented simultaneously with infectious mononucleosis due to primary EBV infection. Acute EBV infection might play an important role in the onset of Graves' disease. These three women complained of a sore throat or neck pain, resembling subacute thyroiditis. In the case of thyrotoxicosis accompanied by sore throat or neck pain, Graves' disease must be distinguished from subacute thyroiditis.
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