De-escalation versus continuation of empirical antimicrobial treatment in severe sepsis: a multicenter non-blinded randomized noninferiority trial

Potentially resistant microorganisms in intubated patients with hospital-acquired pneumonia: the interaction of ecology, shock and risk factors

(2013) Ignacio Martin-Loeches et al.   INTENSIVE CARE MEDICINE

Surviving Sepsis Campaign: International Guidelines for Management of Severe Sepsis and Septic Shock, 2012

(2013) R. P. Dellinger et al.   INTENSIVE CARE MEDICINE

De-escalation of antimicrobial treatment in neutropenic patients with severe sepsis: results from an observational study

(2013) Djamel Mokart et al.   INTENSIVE CARE MEDICINE

De-escalation of empirical therapy is associated with lower mortality in patients with severe sepsis and septic shock

(2013) J. Garnacho-Montero et al.   INTENSIVE CARE MEDICINE

Reporting of Noninferiority and Equivalence Randomized Trials

(2013) Gilda Piaggio et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Antibiotic strategies in severe nosocomial sepsis

(2012) Sarah Heenen et al.   CRITICAL CARE MEDICINE

De-escalation of antimicrobial therapy for bacteraemia due to difficult-to-treat Gram-negative bacilli

(2012) N. Shime et al.   INFECTION

Drotrecogin Alfa (Activated) in Adults with Septic Shock

(2012) V. Marco Ranieri et al.   NEW ENGLAND JOURNAL OF MEDICINE

Impact of Inadequate Empirical Therapy on the Mortality of Patients with Bloodstream Infections: a Propensity Score-Based Analysis

(2011) Pilar Retamar et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Diagnosis, Prevention, and Treatment of Catheter-Associated Urinary Tract Infection in Adults: 2009 International Clinical Practice Guidelines from the Infectious Diseases Society of America

(2011) Thomas M. Hooton et al.   CLINICAL INFECTIOUS DISEASES

Recognition and prevention of multidrug-resistant Gram-negative bacteria in the intensive care unit

(2010) Lisa L. Maragakis   CRITICAL CARE MEDICINE

Diagnosis and Management of Complicated Intra‐abdominal Infection in Adults and Children: Guidelines by the Surgical Infection Society and the Infectious Diseases Society of America

(2009) Joseph S. Solomkin et al.   CLINICAL INFECTIOUS DISEASES

Non-antibiotic treatment for bacterial infections: how to validate chance findings

(2009) L. Leibovici   CLINICAL MICROBIOLOGY AND INFECTION

Non-adherence to guidelines: an avoidable cause of failure of empirical antimicrobial therapy in the presence of difficult-to-treat bacteria

(2009) Frédéric Garcin et al.   INTENSIVE CARE MEDICINE