Article
Medicine, General & Internal
Hong Ren, Li Xie, Zhulin Wang, Xiaoliao Tang, Botao Ning, Teng Teng, Juan Qian, Ying Wang, Lijun Fu, Zhanqi Zhao, Long Xiang
Summary: The study aims to compare the difference in positive end-expiratory pressure (PEEP) selection between chest electrical impedance tomography (EIT) and global dynamic respiratory system compliance (C-rs) in moderate-to-severe pediatric acute respiratory distress syndrome (pARDS). The results suggest that in moderate-to-severe pARDS, PEEP selected based on C-rs might not be inferior to EIT-guided regional ventilation.
FRONTIERS IN MEDICINE
(2022)
Article
Anesthesiology
Xiang Li, He Liu, Jun Wang, Zhi-Lin Ni, Zhong-Xiao Liu, Jia-Li Jiao, Yuan Han, Jun-Li Cao
Summary: This study investigated the effects of dynamic compliance-guided positive end-expiratory pressure (PEEP) on postoperative atelectasis in patients undergoing bariatric surgery. The results showed that dynamic compliance-guided PEEP can reduce postoperative atelectasis in patients undergoing laparoscopic bariatric surgery. However, there was no significant difference in postoperative Pao(2)/Fio(2) between the two groups.
Article
Multidisciplinary Sciences
Ella F. S. Guy, Jennifer L. Knopp, Theodore Lerios, J. Geoffrey Chase
Summary: Continuous positive airway pressure (CPAP) is a commonly used respiratory therapy that assists breathing and prevents airway collapse. The setting of positive end-expiratory pressure (PEEP) is debated and can result in complications. Developing model-based methods for personalized CPAP therapy requires clinical data of lung/CPAP interactions.
Review
Agriculture, Dairy & Animal Science
Elzbieta Stefanik, Olga Drewnowska, Barbara Lisowska, Bernard Turek
Summary: Horses are challenging to anaesthetize due to physiological factors, leading to intraoperative gas exchange disturbances and higher post-operative complications and mortality rates compared to other companion animals. Monitoring methods may not be sufficient alone and combining them is necessary to assess the patient's condition comprehensively. New methods like near-infrared spectroscopy (NIRS) show promise in improving gas monitoring during general anaesthesia in horses.
Article
Critical Care Medicine
Ines Dufour, Alexis Werion, Leila Belkhir, Anastazja Wisniewska, Marie Perrot, Julien De Greef, Gregory Schmit, Jean Cyr Yombi, Xavier Wittebole, Pierre-Francois Laterre, Michel Jadoul, Ludovic Gerard, Johann Morelle
Summary: Studies have shown that low serum uric acid levels are common among COVID-19 patients and are associated with disease severity and progression to respiratory failure requiring mechanical ventilation.
Article
Critical Care Medicine
Luca S. Menga, Luca Delle Cese, Tommaso Rosa, Melania Cesarano, Roberta Scarascia, Teresa Michi, Daniele G. Biasucci, Ersilia Ruggiero, Antonio M. Dell'Anna, Salvatore L. Cutuli, Eloisa S. Tanzarella, Gabriele Pintaudi, Gennaro De Pascale, Claudio Sandroni, Salvatore Maurizio Maggiore, Domenico L. Grieco, Massimo Antonelli
Summary: This study aimed to evaluate the effects of helmet pressure support and continuous positive airway pressure on effort to breathe, lung inflation, and gas exchange in patients with hypoxemia. The results showed that compared to high-flow nasal oxygen, helmet noninvasive ventilation and continuous positive airway pressure had similar effects in reducing effort to breathe, improving oxygenation, and increasing lung volume. Helmet noninvasive ventilation was more effective than continuous positive airway pressure in reducing effort to breathe.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
(2023)
Article
Multidisciplinary Sciences
Samuel J. Raymond, Sam Baker, Yuzhe Liu, Mauricio J. Bustamante, Brett Ley, Michael J. Horzewski, David B. Camarillo, David N. Cornfield
Summary: Most critically ill patients with COVID-19 experience respiratory failure, leading to critical shortages in the supply of mechanical ventilators. In response to this, a low-cost, high-performance ventilator has been designed using medical gases and flow interruption strategy, which has received emergency use authorization from the FDA and can be used in clinical settings.
Article
Pediatrics
Yasemin Ezgi Kostekci, Emel Okulu, Batuhan Bakirarar, Elvis Kraja, Omer Erdeve, Begum Atasay, Saadet Arsan
Summary: This study aimed to compare the short-term outcomes of extremely preterm infants who received NCPAP or NIPPV as an initial treatment of RDS. The results showed that NIPPV as an initial treatment is non-inferior to NCPAP in extremely preterm infants with RDS. Although there were no differences in intubation rate in the first week, mortality, and BPD between the groups, further studies are needed and the synchronization of NIPPV should be evaluated.
FRONTIERS IN PEDIATRICS
(2022)
Article
Multidisciplinary Sciences
Christian M. Jensen, Junia C. Costa, Jens C. Norgaard, Adrian G. Zucco, Bastian Neesgaard, Carsten U. Niemann, Sisse R. Ostrowski, Joanne Reekie, Birgit Holten, Anna Kalhauge, Michael A. Matthay, Jens D. Lundgren, Marie Helleberg, Kasper S. Moestrup
Summary: The existing chest X-ray (CXR)-based scoring systems for COVID-19 pneumonia have low spatial resolution, which needs to be increased for better evaluation of lung anatomy and severity. In this study, the MBrixia score was developed by modifying the Brixia score to improve spatial resolution. The MBrixia score, based on a rule-based quantification of CXR severity in 12 anatomical zones, was applied to CXR images of COVID-19 patients. The results showed a positive correlation between the MBrixia score and the level of respiratory support at the time of CXR imaging. The MBrixia score has the potential to serve as a quantitative surrogate measurement of COVID-19 pneumonia severity, and further research should investigate its validity and predictive capabilities for clinical outcomes.
SCIENTIFIC REPORTS
(2022)
Review
Nursing
Meng Meng, Junhong Zhang, Liying Chen, Liqin Wang
Summary: Meta-analysis of 10 studies showed that CPAP therapy reduced intubation rate and shortened hospital and ICU stay for patients with severe respiratory distress, while NIPPV had no significant effect on in-hospital mortality and ICU admission rate. Further large-sample studies are needed to confirm these findings.
JOURNAL OF CLINICAL NURSING
(2022)
Article
Medicine, General & Internal
Michela Di Pierro, Marco Giani, Alfio Bronco, Francesca Maria Lembo, Roberto Rona, Giacomo Bellani, Giuseppe Foti
Summary: This study aimed to retrospectively describe the results of EIT assessments in patients with COVID-19-associated ARDS and ARDS from other etiologies undergoing V-V ECMO support. The study found that EIT is feasible for adjusting PEEP settings and that there are similarities in respiratory characteristics between C-ARDS and NC-ARDS, but C-ARDS patients have a lower risk of overdistension at higher PEEP levels.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Critical Care Medicine
Anoopindar K. Bhalla, Margaret J. Klein, Guillaume Emeriaud, Yolanda M. Lopez-Fernandez, Natalie Napolitano, Analia Fernandez, Awni M. Al-Subu, Rainer Gedeit, Steven L. Shein, Ryan Nofziger, Deyin Doreen Hsing, George Briassoulis, Stavroula Ilia, Florent Baudin, Byron Enrique Pineres-Olave, Ledys Maria Izquierdo, John C. Lin, Ira M. Cheifetz, Martin C. J. Kneyber, Lincoln Smith, Robinder G. Khemani, Christopher J. L. Newth
Summary: The study described mechanical ventilation management in pediatric acute respiratory distress syndrome and found that nonadherence to lung-protective ventilation principles is common, potentially impacting outcomes. Modifiable factors exist that may improve adherence.
CRITICAL CARE MEDICINE
(2021)
Article
Critical Care Medicine
Alessandro Protti, Alessandro Santini, Francesca Pennati, Chiara Chiurazzi, Massimo Cressoni, Michele Ferrari, Giacomo E. Iapichino, Luca Carenzo, Ezio Lanza, Giorgio Picardo, Pietro Caironi, Andrea Aliverti, Maurizio Cecconi
Summary: Patients with early ARDS due to COVID-19 have a large potential for lung recruitment, but their compliance and Pa-CO2 may not improve with higher PEEP, possibly due to hyperinflation.
Review
Critical Care Medicine
Oriol Roca, Andres Pacheco, Marina Garcia-de-Acilu
Summary: This article is one of the ten reviews selected from the Annual Update in Intensive Care and Emergency Medicine 2021, offering the latest information in the field of intensive care and emergency medicine. Additional selected articles can be found online. More information about this update series is available at the provided link.
Article
Pediatrics
Venkatakrishna B. Kakkilaya, Heather M. Weydig, William E. Smithhart, Shelly D. Renfro, Kristi M. Garcia, Cari M. Brown, Henry He, Sheron A. Wagner, Glenn C. Metoyer, L. Steven Brown, Vishal S. Kapadia, Rashmin C. Savani, Mambarambath A. Jaleel
Summary: Implementation of a quality improvement bundle including CPAP optimization and less invasive surfactant administration decreased CPAP failure and need for MV in preterm infants, especially effective for infants <= 29 weeks' gestational age and showing more significant effects in infants 23 to 26 weeks and 27 to 29 weeks' GA.