Year in review in Intensive Care Medicine 2010: I. Acute renal failure, outcome, risk assessment and ICU performance, sepsis, neuro intensive care and experimentals

Do soluble mediators cause ventilator-induced lung injury and multi-organ failure?

(2010) Thomas Jaecklin et al.   INTENSIVE CARE MEDICINE

Milrinone, dobutamine or epinephrine use in asphyxiated newborn pigs resuscitated with 100% oxygen

(2010) Chloë Joynt et al.   INTENSIVE CARE MEDICINE

Hypercapnic acidosis in ventilator-induced lung injury

(2010) Vanya Peltekova et al.   INTENSIVE CARE MEDICINE

Clinical relevance of 13 cytokine gene polymorphisms in Chinese major trauma patients

(2010) Wei Gu et al.   INTENSIVE CARE MEDICINE

Detecting traumatic internal carotid artery dissection using transcranial Doppler in head-injured patients

(2010) Pierre Bouzat et al.   INTENSIVE CARE MEDICINE

Intensive care reimbursement practices: results from the ICUFUND survey

(2010) Akos Csomos et al.   INTENSIVE CARE MEDICINE

Suspended animation inducer hydrogen sulfide is protective in an in vivo model of ventilator-induced lung injury

(2010) Hamid Aslami et al.   INTENSIVE CARE MEDICINE

Implementing glucose control in intensive care: a multicenter trial using statistical process control

(2010) Saeid Eslami et al.   INTENSIVE CARE MEDICINE

The interrater reliability of SAPS II and SAPS 3

(2010) K. Strand et al.   INTENSIVE CARE MEDICINE

Are small hospitals with small intensive care units able to treat patients with severe sepsis?

(2010) Matti Reinikainen et al.   INTENSIVE CARE MEDICINE

Early postoperative delirium after open-heart cardiac surgery is associated with decreased bispectral EEG and increased cortisol and interleukin-6

(2010) Konstanze Plaschke et al.   INTENSIVE CARE MEDICINE

The long way of biomarkers: from bench to bedside

(2010) Haibo Zhang et al.   INTENSIVE CARE MEDICINE

Effects of blood glucose transcription mismatches on a computer-based intensive insulin therapy protocol

(2010) Thomas R. Campion et al.   INTENSIVE CARE MEDICINE

Cognitive improvement during continuous sedation in critically ill, awake and responsive patients: the Acute Neurological ICU Sedation Trial (ANIST)

(2010) Marek A. Mirski et al.   INTENSIVE CARE MEDICINE

Characterizing the risk profiles of intensive care units

(2010) Rui P. Moreno et al.   INTENSIVE CARE MEDICINE

Infusion fluids contain harmful glucose degradation products

(2010) Anna Bryland et al.   INTENSIVE CARE MEDICINE

EUROTHERM3235Trial

(2010) Peter J. D. Andrews et al.   INTENSIVE CARE MEDICINE

Increased muscle-to-serum lactate gradient predicts progression towards septic shock in septic patients

(2010) Bruno Levy et al.   INTENSIVE CARE MEDICINE

Human and experimental septic shock are characterized by depletion of lipid droplets in the adrenals

(2010) Andrea Polito et al.   INTENSIVE CARE MEDICINE

The RAGE axis in systemic inflammation, acute lung injury and myocardial dysfunction: an important therapeutic target?

(2010) Benedict C. Creagh-Brown et al.   INTENSIVE CARE MEDICINE

Regional tidal ventilation and compliance during a stepwise vital capacity manoeuvre

(2010) Peter A. Dargaville et al.   INTENSIVE CARE MEDICINE

Reproduction of inert gas and oxygenation data: a comparison of the MIGET and a simple model of pulmonary gas exchange

(2010) Stephen E. Rees et al.   INTENSIVE CARE MEDICINE

Prevention of adverse drug reactions in intensive care patients by personal intervention based on an electronic clinical decision support system

(2010) Thilo Bertsche et al.   INTENSIVE CARE MEDICINE

Pulmonary-derived phosphoinositide 3-kinase gamma (PI3Kγ) contributes to ventilator-induced lung injury and edema

(2010) Vito Fanelli et al.   INTENSIVE CARE MEDICINE

Monitoring the microcirculation in the critically ill patient: current methods and future approaches

(2010) Daniel De Backer et al.   INTENSIVE CARE MEDICINE

Toll-like receptors 2 and 4: initiators of non-septic inflammation in critical care medicine?

(2010) Emmanuel Lorne et al.   INTENSIVE CARE MEDICINE

Hormonal status and ICU-acquired paresis in critically ill patients

(2010) Tarek Sharshar et al.   INTENSIVE CARE MEDICINE

Olprinone attenuates the development of ischemia/reperfusion injury of the gut

(2010) Concetta Crisafulli et al.   INTENSIVE CARE MEDICINE

Validation of four prognostic scores in patients with cancer admitted to Brazilian intensive care units: results from a prospective multicenter study

(2010) Márcio Soares et al.   INTENSIVE CARE MEDICINE

Fall in circulating mononuclear cell mitochondrial DNA content in human sepsis

(2010) Angela Pyle et al.   INTENSIVE CARE MEDICINE

Normal citratemia and metabolic tolerance of citrate anticoagulation for hemodiafiltration in severe septic shock burn patients

(2010) Filippo Mariano et al.   INTENSIVE CARE MEDICINE

Acute kidney injury in elderly intensive care patients: a review

(2010) Alexandra Chronopoulos et al.   INTENSIVE CARE MEDICINE

Mechanical ventilation aggravates transfusion-related acute lung injury induced by MHC-I class antibodies

(2010) A. P. J. Vlaar et al.   INTENSIVE CARE MEDICINE

Effects of terbutaline on circulatory failure and organ dysfunction induced by peritonitis in rats

(2010) Cheng-Ming Tsao et al.   INTENSIVE CARE MEDICINE

The role of vasoactive agents in the resuscitation of microvascular perfusion and tissue oxygenation in critically ill patients

(2010) E. Christiaan Boerma et al.   INTENSIVE CARE MEDICINE

Ward mortality after ICU discharge: a multicenter validation of the Sabadell score

(2010) Rafael Fernandez et al.   INTENSIVE CARE MEDICINE

Vascular hyporesponsiveness to vasopressors in septic shock: from bench to bedside

(2010) B. Levy et al.   INTENSIVE CARE MEDICINE

Assisted ventilation modes reduce the expression of lung inflammatory and fibrogenic mediators in a model of mild acute lung injury

(2010) Felipe Saddy et al.   INTENSIVE CARE MEDICINE

The endothelium: physiological functions and role in microcirculatory failure during severe sepsis

(2010) H. Ait-Oufella et al.   INTENSIVE CARE MEDICINE

Soluble ST2 plasma concentrations predict mortality in severe sepsis

(2010) Jacobien J. Hoogerwerf et al.   INTENSIVE CARE MEDICINE

Persisting high levels of plasma pentraxin 3 over the first days after severe sepsis and septic shock onset are associated with mortality

(2010) Tommaso Mauri et al.   INTENSIVE CARE MEDICINE

Impact of body mass on incidence and prognosis of acute kidney injury requiring renal replacement therapy

(2010) Wilfred Druml et al.   INTENSIVE CARE MEDICINE

Hypoalbuminemia and acute kidney injury: a meta-analysis of observational clinical studies

(2010) Christian J. Wiedermann et al.   INTENSIVE CARE MEDICINE

Impaired microvascular perfusion in sepsis requires activated coagulation and P-selectin-mediated platelet adhesion in capillaries

(2010) Dan Secor et al.   INTENSIVE CARE MEDICINE

Outcome of acute kidney injury in severe burns: a systematic review and meta-analysis

(2010) Nele Brusselaers et al.   INTENSIVE CARE MEDICINE

Inter-rater reliability of manual muscle strength testing in ICU survivors and simulated patients

(2010) Eddy Fan et al.   INTENSIVE CARE MEDICINE

Neutrophil gelatinase-associated lipocalin in adult septic patients with and without acute kidney injury

(2010) Johan Mårtensson et al.   INTENSIVE CARE MEDICINE

Reasons for refusal of admission to intensive care and impact on mortality

(2010) Gaetano Iapichino et al.   INTENSIVE CARE MEDICINE

The impact of experimental hypoperfusion on subsequent kidney function

(2010) Takao Saotome et al.   INTENSIVE CARE MEDICINE

Mechanical ventilation modulates Toll-like receptor signaling pathway in a sepsis-induced lung injury model

(2010) Jesús Villar et al.   INTENSIVE CARE MEDICINE

The Surviving Sepsis Campaign: results of an international guideline-based performance improvement program targeting severe sepsis

(2010) Mitchell M. Levy et al.   INTENSIVE CARE MEDICINE

Invasive and noninvasive assessment of cerebral oxygenation in patients with severe traumatic brain injury

(2010) Santiago R. Leal-Noval et al.   INTENSIVE CARE MEDICINE

Time trends in outcome of subarachnoid hemorrhage: Population-based study and systematic review

(2010) C. E. Lovelock et al.   NEUROLOGY

Citrate anticoagulation for continuous venovenous hemofiltration*

(2009) Heleen M. Oudemans-van Straaten et al.   CRITICAL CARE MEDICINE

Early physiological and biological features in three animal models of induced acute lung injury

(2009) Josefina López-Aguilar et al.   INTENSIVE CARE MEDICINE

The impact of crystalloid and colloid infusion on the kidney in rodent sepsis

(2009) Martin Alexander Schick et al.   INTENSIVE CARE MEDICINE

A multiparameter panel method for outcome prediction following aneurysmal subarachnoid hemorrhage

(2009) Natacha Turck et al.   INTENSIVE CARE MEDICINE

Open the doors of the ICU to patients with malignancies and neurological complications

(2009) Michael Piagnerelli et al.   INTENSIVE CARE MEDICINE

Central neurological complications in critically ill patients with malignancies

(2009) Stéphane Legriel et al.   INTENSIVE CARE MEDICINE

PTX3 as a potential biomarker of acute lung injury: supporting evidence from animal experimentation

(2009) Xiaolin He et al.   INTENSIVE CARE MEDICINE

Secondary decline of cerebral autoregulation is associated with worse outcome after intracerebral hemorrhage

(2009) Matthias Reinhard et al.   INTENSIVE CARE MEDICINE

Biomarkers and acute kidney injury: dining with the Fisher King?

(2009) Catherine S. C. Bouman et al.   INTENSIVE CARE MEDICINE

The bispectral index and suppression ratio are very early predictors of neurological outcome during therapeutic hypothermia after cardiac arrest

(2009) David B. Seder et al.   INTENSIVE CARE MEDICINE

Angiopoietin-2 in patients requiring renal replacement therapy in the ICU: relation to acute kidney injury, multiple organ dysfunction syndrome and outcome

(2009) Philipp Kümpers et al.   INTENSIVE CARE MEDICINE

Increased plasma thioredoxin levels in patients with sepsis: positive association with macrophage migration inhibitory factor

(2009) Susannah K. Leaver et al.   INTENSIVE CARE MEDICINE

Epidemiology of Mechanical Ventilation: Analysis of the SAPS 3 Database

(2009) Philipp G. H. Metnitz et al.   INTENSIVE CARE MEDICINE

Prognostic factors in non-exertional heatstroke

(2009) Pierre Hausfater et al.   INTENSIVE CARE MEDICINE

The effects of vasopressin on acute kidney injury in septic shock

(2009) Anthony C. Gordon et al.   INTENSIVE CARE MEDICINE

Usefulness of a clinical diagnosis of ICU-acquired paresis to predict outcome in patients with SIRS and acute respiratory failure

(2009) Anna-Giulia Brunello et al.   INTENSIVE CARE MEDICINE

Incidence and prognosis of dysnatremias present on ICU admission

(2009) Georg-Christian Funk et al.   INTENSIVE CARE MEDICINE

Bacillus anthracis cell wall produces injurious inflammation but paradoxically decreases the lethality of anthrax lethal toxin in a rat model

(2009) Xizhong Cui et al.   INTENSIVE CARE MEDICINE

Prevention of acute kidney injury and protection of renal function in the intensive care unit

(2009) Michael Joannidis et al.   INTENSIVE CARE MEDICINE

Plasma neutrophil gelatinase-associated lipocalin is an early biomarker for acute kidney injury in an adult ICU population

(2009) Dinna N. Cruz et al.   INTENSIVE CARE MEDICINE

Beneficial effects of the heme oxygenase-1/carbon monoxide system in patients with severe sepsis/septic shock

(2009) Shoji Takaki et al.   INTENSIVE CARE MEDICINE

Plasma and urine neutrophil gelatinase-associated lipocalin in septic versus non-septic acute kidney injury in critical illness

(2009) Sean M. Bagshaw et al.   INTENSIVE CARE MEDICINE

Histopathology of septic shock induced acute kidney injury: apoptosis and leukocytic infiltration

(2009) Nicolas Lerolle et al.   INTENSIVE CARE MEDICINE

Obesity is associated with increased morbidity but not mortality in critically ill patients

(2008) Yasser Sakr et al.   INTENSIVE CARE MEDICINE