Article
Medicine, General & Internal
A. W. Thille, A. Gacouin, Remi Coudroy, Stephan Ehrmann, Jean-Pierre Frat, Mai-Anh Nay, Christophe Guitton, Damien Contou, Guylaine Labro, Jean Reignier, Gael Pradel, Gaetan Beduneau, Laurence Dangers, Clement Saccheri, Gwenael Prat, Guillaume Lacave, Nicholas Sedillot, Nicolas Terzi, Beatrice La Combe, Jean-Paul Mira, Antoine Romen, Marie-Ange Azais, Anahita Rouze, Jerome Devaquet, Agathe Delbove, Martin Dres, Jeremy Bourenne, Alexandre Lautrette, Joe de Keizer, Stephanie Ragot, Jean-Pierre Frat
Summary: For patients at high risk of extubation failure, using pressure-support ventilation (PSV) or a T-piece for spontaneous-breathing trials did not result in significantly different ventilator-free days at day 28.
NEW ENGLAND JOURNAL OF MEDICINE
(2022)
Article
Critical Care Medicine
Arnaud Gacouin, Mathieu Lesouhaitier, Florian Reizine, Benoit Painvin, Adel Maamar, Christophe Camus, Yves Le Tulzo, Jean Marc Tadie
Summary: The study aimed to compare the reintubation rates at day 7 after extubation between 1-hour T-piece and 1-hour PS0 ZEEP spontaneous breathing trials, and found that they were associated with similar rates.
JOURNAL OF CRITICAL CARE
(2022)
Article
Respiratory System
Jia Song, Zhixian Qian, Haixiang Zhang, Minjia Wang, Yihua Yu, Cong Ye, Weihang Hu, Shijin Gong
Summary: This study found that two weaning indices determined by bedside ultrasonography, DE-RSBI (RR/DE) and DTF-RSBI (RR/DTF), were more accurate in predicting weaning outcome during a PSV SBT compared to the traditional RSBI.
BMC PULMONARY MEDICINE
(2022)
Article
Multidisciplinary Sciences
Maria Consuelo Bachmann, Pablo Cruces, Franco Diaz, Vanessa Oviedo, Mariela Goich, Jose Fuenzalida, Luis Felipe Damiani, Roque Basoalto, Yorschua Jalil, David Carpio, Niki Hamidi Vadeghani, Rodrigo Cornejo, Maximiliano Rovegno, Guillermo Bugedo, Alejandro Bruhn, Jaime Retamal
Summary: Spontaneous breathing during the early stage of acute respiratory failure can lead to lung injury, but this can be prevented by early application of controlled mechanical ventilation. However, late application of controlled mechanical ventilation is ineffective in preventing lung injury in a lung collapse model.
SCIENTIFIC REPORTS
(2022)
Article
Critical Care Medicine
Fabio Varon-Vega, Luis F. Giraldo-Cadavid, Ana Maria Uribe, Adriana Rincon, Jonathan Palacios, Stephanie Crevoisier, Eduardo Tuta-Quintero, Lina Ordonez, Natalia Boada, Paola Rincon, Marcela Poveda, Pablo Monedero
Summary: The study found that objective measurements of cough and diaphragmatic contraction velocity can predict the success of the spontaneous breathing trial. The equation for predicting successful extubation, which includes values for the trial, cough, and diaphragmatic contraction velocity, showed excellent discriminative capacity.
Article
Respiratory System
Jefta van Dijk, Alette A. Koopman, Limme B. de Langen, Sandra Dijkstra, Johannes G. M. Burgerhof, Robert G. T. Blokpoel, Martin C. J. Kneyber
Summary: In this study, we investigated the impact of different modes on patient effort during pediatric ventilator liberation and studied whether reducing pressure support would increase patient effort. The results showed that patient effort did not increase in the continuous spontaneous ventilation mode, and reducing pressure support did not lead to clinically relevant increases in patient effort.
RESPIRATORY RESEARCH
(2022)
Article
Critical Care Medicine
Michele C. Balas, Alai Tan, Lorraine C. Mion, Brenda Pun, Jin Jun, Audrey Brockman, Jinjian Mu, E. Wesley Ely, Eduard E. Vasilevskis
Summary: This study identifies modifiable factors associated with the performance of spontaneous awakening trials and spontaneous breathing trials, providing recommendations for the development and testing of implementation interventions.
Article
Anesthesiology
Heejoon Jeong, Pisitpitayasaree Tanatporn, Hyun Joo Ahn, Mikyung Yang, Jie Ae Kim, Hyean Yeo, Woojin Kim
Summary: The study showed that pressure support ventilation during emergence from anesthesia reduced the incidence of postoperative atelectasis in patients undergoing laparoscopic surgery. Patients who received pressure support ventilation had better lung function and oxygenation status postoperatively compared to those who received intermittent manual assistance.
Article
Peripheral Vascular Disease
Ming-Hann Shin, Han-Shui Hsu, Jung-Yien Chien, Chun-kai Huang, Lu-Cheng Kuo, Tien-Mei Shun, Yi-Tsung Lin, Yu-Chang Yeh
Summary: This study aimed to assess the association between changes in sublingual microcirculation after a spontaneous breathing trial (SBT) and successful extubation. The study found that at the end of the SBT, the failed extubation group had significantly lower total small vessel density, perfused small vessel density, proportion of perfused small vessels, and microvascular flow index compared to the successful extubation group. The study also found no significant differences in weaning and microcirculatory parameters between the two groups before the SBT.
MICROVASCULAR RESEARCH
(2023)
Article
Respiratory System
Soo Jin Na, Ryoung-Eun Ko, Jimyoung Nam, Myeong Gyun Ko, Kyeongman Jeon
Summary: There is no significant difference in the success rate of weaning between PSV and T-piece methods for SBT in critically ill patients. However, PSV can shorten the weaning process without increasing the risk of reintubation.
RESPIRATORY RESEARCH
(2022)
Article
Pediatrics
Zhe Li, Jiang Xue, Xin-Yuan Guo, Fang Wang, Xue Zhang, Qi Li, Jing-Liang Tang, Juan Ji, Guang-Jun Du
Summary: This study aimed to investigate the accuracy of SBT using a combined CPAP + low-level PSV model to predict the outcomes of extubation in very preterm infants, and found that it has high sensitivity and specificity for predicting extubation outcomes in this population.
Article
Critical Care Medicine
Shaurya Taran, Federico Angriman, Ruxandra Pinto, Bruno L. Ferreyro, Andre Carlos Kajdacsy-Balla Amaral
Summary: This retrospective cohort study found discrepancies in factors associated with withholding extubation and extubation failure in the ICU setting. Age and female sex were associated with withholding extubation but not extubation failure, while acute cardiovascular conditions and intubation for hypoxemic respiratory failure were associated with higher risk of extubation failure but not withholding extubation attempts.
CRITICAL CARE MEDICINE
(2021)
Article
Critical Care Medicine
Daniel H. Arellano, Roberto Brito, Caio C. A. Morais, Pablo Ruiz-Rudolph, Abraham I. J. Gajardo, Dannette V. Guinez, Marioli T. Lazo, Ivan Ramirez, Veronica A. Rojas, Maria A. Cerda, Juan N. Medel, Victor Illanes, Nivia R. Estuardo, Alejandro R. Bruhn, Laurent J. Brochard, Marcelo B. P. Amato, Rodrigo A. Cornejo
Summary: A study comparing NAVA and PAV+ with PSV found that although NAVA and PAV+ were better at tracking patient respiratory effort compared to PSV, the occurrence of pendelluft was higher in patients resolving ARDS. Additionally, the magnitude of pendelluft was associated with respiratory effort and intrinsic drive.
ANNALS OF INTENSIVE CARE
(2023)
Review
Medicine, General & Internal
Li-Juan Yi, Xu Tian, Min Chen, Jin-Mei Lei, Na Xiao, Maria F. Jimenez-Herrera
Summary: The study compared and ranked four common modes of spontaneous breathing trial (SBT) in critically ill patients receiving mechanical ventilation. Results showed that automatic tube compensation (ATC) had higher success rates in weaning off the ventilator and lower reintubation rates than continuous positive airway pressure (CPAP). Further research is needed to confirm these findings.
FRONTIERS IN MEDICINE
(2021)
Article
Critical Care Medicine
Bruno da Silva Guimaraes, Leonardo Cordeiro de Souza, Hebe Faria Cordeiro, Thiago Loureiro Regis, Cristiane Almeida Leite, Fernanda Patricio Puga, Sergio Hernando Alvim, Jocemir Ronaldo Lugon
Summary: The study showed that inspiratory muscle training program with an electronic resistive loading device led to significant improvements in muscle strength and positive impacts on ICU survival and successful weaning rates.
CRITICAL CARE MEDICINE
(2021)