Involvement of superoxide and nitric oxide in BRAFV600E inhibitor PLX4032-induced growth inhibition of melanoma cells

Mitochondrial oxidative stress is the achille’s heel of melanoma cells resistant to Braf-mutant inhibitor

(2015) Paola Corazao-Rozas et al.   Oncotarget

DNA-Templated Biomimetic Enzyme Sheets on Carbon Nanotubes to Sensitively In Situ Detect Superoxide Anions Released from Cells

(2014) Xiaoqing Ma et al.   ADVANCED FUNCTIONAL MATERIALS

Electrodes/paper sandwich devices for in situ sensing of hydrogen peroxide secretion from cells growing in gels-in-paper 3-dimensional matrix

(2014) ZhuanZhuan Shi et al.   Analytical Methods

Pathologic role of glial nitric oxide in adult and pediatric neuroinflammatory diseases

(2014) Mehdi Ghasemi et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Endothelial Nitric Oxide Synthase and Superoxide Mediate Hemodynamic Initiation of Intracranial Aneurysms

(2014) Nicholas Liaw et al.   PLoS One

Overcoming Intrinsic Multidrug Resistance in Melanoma by Blocking the Mitochondrial Respiratory Chain of Slow-Cycling JARID1Bhigh Cells

(2013) Alexander Roesch et al.   CANCER CELL

Novel small molecule Raf kinase inhibitors for targeted cancer therapeutics

(2012) Do-Hee Kim et al.   ARCHIVES OF PHARMACAL RESEARCH

Survival in BRAF V600–Mutant Advanced Melanoma Treated with Vemurafenib

(2012) Jeffrey A. Sosman et al.   NEW ENGLAND JOURNAL OF MEDICINE

Nitric Oxide-Derived Oxidants with a Focus on Peroxynitrite: Molecular Targets,Cellular Responses and Therapeutic Implications

(2011) P. Calcerrada et al.   CURRENT PHARMACEUTICAL DESIGN

Measuring reactive oxygen and nitrogen species with fluorescent probes: challenges and limitations

(2011) Balaraman Kalyanaraman et al.   FREE RADICAL BIOLOGY AND MEDICINE

The CSPG4-specific monoclonal antibody enhances and prolongs the effects of the BRAF inhibitor in melanoma cells

(2011) Ling Yu et al.   IMMUNOLOGIC RESEARCH

Biointerface by Cell Growth on Layered Graphene-Artificial Peroxidase-Protein Nanostructure for In Situ Quantitative Molecular Detection

(2010) Chun Xian Guo et al.   ADVANCED MATERIALS

Superoxide anion and hydrogen peroxide-induced signaling and damage in angiotensin II and aldosterone action

(2010) Nina Queisser et al.   BIOLOGICAL CHEMISTRY

BRAF Inhibitors: Research Accelerates in Wake of Positive Findings

(2010) V. Brower   JNCI-Journal of the National Cancer Institute

Designing molecular materials and strategies for the electrochemical detection of nitric oxide, superoxide and peroxynitrite in biological systems

(2010) Fethi Bedioui et al.   PHYSICAL CHEMISTRY CHEMICAL PHYSICS

The RAF inhibitor PLX4032 inhibits ERK signaling and tumor cell proliferation in a V600E BRAF-selective manner

(2010) E. W. Joseph et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Proton pump inhibition induces autophagy as a survival mechanism following oxidative stress in human melanoma cells

(2010) M L Marino et al.   Cell Death & Disease

Integrating BRAF/MEK inhibitors into combination therapy for melanoma

(2009) K S M Smalley et al.   BRITISH JOURNAL OF CANCER

Advances in Targeting the Ras/Raf/MEK/Erk Mitogen-Activated Protein Kinase Cascade with MEK Inhibitors for Cancer Therapy

(2008) B. B. Friday et al.   CLINICAL CANCER RESEARCH