CD19-antigen specific nanoscale liposomal formulation of a SYK P-site inhibitor causes apoptotic destruction of human B-precursor leukemia cells

Nanoscale liposomal formulation of a SYK P-site inhibitor against B-precursor leukemia

(2013) F. M. Uckun et al.   BLOOD

Biotargeted nanomedicines for cancer: six tenets before you begin

(2013) Michael S Goldberg et al.   Nanomedicine

CD19-Targeted T Cells Rapidly Induce Molecular Remissions in Adults with Chemotherapy-Refractory Acute Lymphoblastic Leukemia

(2013) R. J. Brentjens et al.   Science Translational Medicine

How I treat relapsed childhood acute lymphoblastic leukemia

(2012) F. Locatelli et al.   BLOOD

Rational design of an immunoconjugate for selective knock-down of leukemia-specific E2A–PBX1 fusion gene expression in human Pre-B leukemia

(2012) Fatih M. Uckun et al.   Integrative Biology

Malignant stem cells in childhood acute lymphoblastic leukemia: The stem cell concept revisited

(2011) H. Josef Vormoor   CELL CYCLE

Targeting SYK kinase-dependent anti-apoptotic resistance pathway in B-lineage acute lymphoblastic leukaemia (ALL) cells with a potent SYK inhibitory pentapeptide mimic

(2010) Fatih M. Uckun et al.   BRITISH JOURNAL OF HAEMATOLOGY

Spleen tyrosine kinase as a molecular target for treatment of leukemias and lymphomas

(2010) Fatih M Uckun et al.   Expert Review of Anticancer Therapy

Targeting and internalization of sterically stabilized liposome modified with ZCH-4-2E8

(2010) Jingying Zhang et al.   Journal of Huazhong University of Science and Technology-Medical Sciences

Complete remission after blinatumomab-induced donor T-cell activation in three pediatric patients with post-transplant relapsed acute lymphoblastic leukemia

(2010) R Handgretinger et al.   LEUKEMIA

STAT3 is a substrate of SYK tyrosine kinase in B-lineage leukemia/lymphoma cells exposed to oxidative stress

(2010) F. M. Uckun et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

In Childhood Acute Lymphoblastic Leukemia, Blasts at Different Stages of Immunophenotypic Maturation Have Stem Cell Properties

(2008) Christoph le Viseur et al.   CANCER CELL

Therapeutic Nanoparticles for Drug Delivery in Cancer

(2008) K. Cho et al.   CLINICAL CANCER RESEARCH

Bone-marrow relapse in paediatric acute lymphoblastic leukaemia

(2008) L Charles Bailey et al.   LANCET ONCOLOGY

CD34+CD38+CD19+ as well as CD34+CD38−CD19+ cells are leukemia-initiating cells with self-renewal capacity in human B-precursor ALL

(2008) Y Kong et al.   LEUKEMIA

Ten-year survival of children with acute lymphoblastic leukemia: A report from the Children's Oncology Group

(2008) Michael E. Trigg et al.   LEUKEMIA & LYMPHOMA

Nanoparticle therapeutics: an emerging treatment modality for cancer

(2008) Mark E. Davis et al.   NATURE REVIEWS DRUG DISCOVERY

Treatment of Childhood Acute Lymphoblastic Leukemia

(2008) Martin Stanulla et al.   SEMINARS IN HEMATOLOGY

Targeted delivery of anti-CD19 liposomal doxorubicin in B-cell lymphoma: A comparison of whole monoclonal antibody, Fab′ fragments and single chain Fv

(2007) Wilson W.K. Cheng et al.   JOURNAL OF CONTROLLED RELEASE