Article
Biochemistry & Molecular Biology
Mandeep Dahiya, Rajendra Awasthi, Jaya Parkash Yadav, Shammi Sharma, Kamal Dua, Harish Dureja
Summary: This study developed magnetic nanoparticles by embedding magnetite particles in the drug-loaded, crosslinked matrix of chitosan. Sorafenib tosylate-loaded magnetic nanoparticles were prepared and showed superparamagnetic nature. The IC50 value of the nanoparticles in HepG2 cells was 54.75 mu g/mL.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Materials Science, Biomaterials
Mingxi Li, Dongwen Deng, Zhe Chen, Wentao Liu, Gutian Zhao, Yu Zhang, Fang Yang, Zhonghua Ni
Summary: Polymeric biodegradable stents (BDSs) show great potential in cardiovascular disease treatment due to their good biosafety and bioabsorbability. However, the low density of the polymer makes it difficult to visualize with medical imaging techniques, hindering precise localization and evaluation of BDSs. In this study, Fe3O4 superparamagnetic iron oxide nanoparticles (SPIONs) were synthesized to modify BDSs, enabling their visualization and long-term monitoring under MR imaging. Additionally, an image analysis method based on gray value changes was established to assess stent degradation. This study demonstrates the potential of SPION-modified BDSs for precise localization and non-invasive monitoring of degradation, as well as multimodal imaging assessment of vascular endothelial remodeling.
JOURNAL OF MATERIALS CHEMISTRY B
(2023)
Article
Environmental Sciences
Mengying Xu, Yichao Deng, Shanhu Li, Jingyan Zheng, Jieyu Liu, Pier-Luc Tremblay, Tian Zhang
Summary: Effective strategies are critical to improve charge separation in semiconductor particles for enhancing the photodegradation of organic pollutants. In this study, Bi2MoO6 (BMOMOF) nanoparticles and quantum dots were synthesized from a bismuth-based metal-organic framework (Bi-MOF) precursor. The combination of surface defects, NPs and QDs in BMOMOF improved charge separation and facilitated redox reactions. The BMOMOF photocatalyst was more efficient in degrading widely-used antibiotics and carcinogenic pollutants compared to BMO derived from uncoordinated Bi. Loading BMOMOF on biopolymer bacterial cellulose significantly enhanced photocatalytic performance and facilitated material recovery after water treatment processes.
Article
Chemistry, Multidisciplinary
Weiheng Xu, Dharneedar Ravichandran, Sayli Jambhulkar, Yuxiang Zhu, Kenan Song
Summary: Carbon nanotube-reinforced polymer fibers with precise microstructural control of CNTs show significant mechanical enhancement through a new methodology combining dry-jet-wet spinning and forced assembly, leading to scalable fabrication of fiber composites with alternating layers of PAN and CNT/PAN. This method not only improves CNT dispersion and orientation, but also holds enormous potential for versatile applications in polymer nanocomposites.
ADVANCED FUNCTIONAL MATERIALS
(2021)
Article
Materials Science, Ceramics
Meng-Xin Ren, Yu-Qian Wang, Bu-Yue Lei, Xiao-Xiao Yang, Yun-Lei Hou, Wen-Jie Meng, Dong-Lin Zhao
Summary: This study synthesized magnetite nanoparticles anchored on graphene oxide and loaded them with an anti-cancer drug to create a promising carrier for magnetic hyperthermia therapy. The structure and heating efficiency of the nanoparticles were investigated, showing potential as targeted drug carriers and thermoseeds in MHT.
CERAMICS INTERNATIONAL
(2021)
Article
Chemistry, Multidisciplinary
Ahmed M. Azzam, Mohamed A. Shenashen, Mohamed S. Selim, Bayaumy Mostafa, Ahmed Tawfik, Sherif A. El-Safty
Summary: In this study, a novel nanomaterial was fabricated for the rapid detection and elimination of bacterial pathogens. The nanospheres exhibited high selectivity and capture efficiency, enabling the rapid detection of Bacillus cereus within 15 minutes.
Article
Fisheries
Zhensheng Wang, Xingchen Huo, Yanqi Zhang, Yang Gao, Jianguo Su
Summary: This study demonstrates that nanoparticle CMCS-20a loaded with carboxymethyl chitosan (CMCS) has a good preventive effect on bacterial diseases in aquaculture. CMCS-20a can effectively kill bacteria and reduce the influence of external factors, it is almost non-toxic to fish cells, and can increase the activity of important antibacterial substances in the serum. Furthermore, CMCS-20a can improve fish survival rate by regulating inflammation responses, reducing bacterial burdens, and alleviating tissue lesions.
Article
Food Science & Technology
Sadin Ozdemir, Zeynep Turkan, Ersin Kilinc, Elif Esra Altuner, Fatih Sen
Summary: This study investigates the effectiveness of Anoxybacillus flavithermus-functionalized iron oxide nanoparticles as a magnetic sorbent for preconcentrating toxic metal ions. Optimal conditions were determined through the adjustment of experimental parameters. The feasibility of the method was verified through testing on certified reference materials.
FOOD AND CHEMICAL TOXICOLOGY
(2022)
Article
Engineering, Environmental
Thomas Myeongseok Koo, Min Jun Ko, Bum Chul Park, Myeong Soo Kim, Young Keun Kim
Summary: By developing a structure with terbium ion (Tb3+)-coordinated magnetite (Fe3O4) nanoparticle, it is possible to achieve more accurate detection of DPA and improve the detection limit through the application of a magnetic field. The detection system exhibits a significantly lower detection limit than the infectious dosage of anthrax, with high selectivity and chemical stability.
JOURNAL OF HAZARDOUS MATERIALS
(2021)
Article
Environmental Sciences
Sadin Ozdemir, Zeynep Turkan, Ersin Kilinc, Ramazan Bayat, Mustafa Soylak, Fatih Sen
Summary: A novel preconcentration technique was developed for the simultaneous preconcentrations of Cu(II) and Mn(II), using Bacillus cereus loaded magnetic gamma-Fe2O3 nanoparticles as support materials on solid-phase extraction procedure. The optimized conditions were pH 6.0, flow rate of 3 mL min(-1), eluent of 5 mL 1 mol L-1 HCl, biomass of 200 mg, and magnetic gamma-Fe2O3 nanoparticles as support material. The developed method showed high preconcentration factors, low LOD values, and low RSD values, with extraction recoveries higher than 98%.
ENVIRONMENTAL RESEARCH
(2022)
Article
Spectroscopy
Faten Farouk, Shereen Essam, Amany Abdel-Motaleb, Rana El-Shimy, Wolfgang Fritzsche, Hassan Mohamed El-Said Azzaz
Summary: A comprehensive assay utilizing FTIR and spectral classification algorithm was developed for fast and accurate detection of bacterial contamination in fresh produce. The procedure involved sample soaking, magnetic nanoparticles capturing, and FTIR scanning, followed by comparison with a bacterial species database. The developed method demonstrated excellent accuracy in detecting bacterial contamination in market samples.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2022)
Article
Materials Science, Multidisciplinary
Yue Ma, M. S. Kim, Benjamin A. Stickler
Summary: Spin angular momentum and mechanical rotation contribute to total angular momentum of rigid bodies, leading to spin-rotational coupling; Rotations of symmetric nanorotors can be strongly affected by intrinsic spins; This opens the door to torque-free schemes for controlling rotations at the quantum level.
Article
Pharmacology & Pharmacy
Mandeep Dahiya, Rajendra Awasthi, Kamal Dua, Harish Dureja
Summary: In this study, magnetic nanoparticles were prepared using an emulsion solvent evaporation method and optimized using Box Behnken design. The optimized nanoparticles showed a mean particle size range of 71.81 +/- 4.4 to 384.1 +/- 10.5 nm, a polydispersity index range of 0.203 +/- 0.008 to 0.777 +/- 0.010, and a zeta potential range of -34.4 +/- 3.1 to -10.2 +/- 0.6 mV. The entrapment efficiency was 84.64 +/- 0.78%. TEM image confirmed the formation of spherical nanoparticles. The optimized formulation released 25.18%-56.63% and 54.38%-90.56% of loaded drug in phosphate buffer and 0.1 N HCl, respectively. The IC50 value of the optimized formulation in HepG2 cell lines was 38.12 μg/mL. The XRD analysis confirmed the amorphous form of the loaded drug. The average surface roughness for the magnetite and optimized formulation was 5.27025 nm and 8.29138 nm, respectively. The magnetization saturation for magnetite and optimized formulation was 28.58 emu/g and 25.46 emu/g, respectively. The electron paramagnetic resonance spectroscopy revealed a g-Lande factor of 4.30 for pure magnetite and 4.24 for the optimized formulation, indicating the superparamagnetic nature of the particles.
JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY
(2023)
Article
Biochemical Research Methods
Hironobu Fujita, Ayane Osaku, Yuto Sakane, Koki Yoshida, Kayoko Yamada, Seia Nara, Takahito Mukai, Masayuki Su'etsugu
Summary: In this study, the negative supercoiling of whole genomes extracted from Escherichia coli and Vibrio natriegens cells was achieved using a nick/gap repair and negative supercoiling reaction. Supercoiled chromosomes were separated by size and enzymatic replication of chromosomes was also achieved. The development of genetically stable chromosomes allowed for successful electroporation and will greatly accelerate the democratization of genome synthetic biology.
ACS SYNTHETIC BIOLOGY
(2022)
Review
Pharmacology & Pharmacy
Yuan-Pin Hung, Yu-Fon Chen, Pei-Jane Tsai, I-Hsiu Huang, Wen-Chien Ko, Jeng-Shiung Jan
Summary: Bacteria-targeting nanomaterials have been widely used for diagnosis and treatment of bacterial infectious diseases, showing great potential as antimicrobial agents. These materials prevent bacterial colonization and spreading, benefiting biomaterial implants. Tailoring nanomaterials for wound repair and incorporating immune activating adjuvants can improve function and prevent bacterial infections.
