SHARPIN overexpression induces tumorigenesis in human prostate cancer LNCaP, DU145 and PC-3 cells via NF-κB/ERK/Akt signaling pathway

p-21 activated kinase 4 promotes proliferation and survival of pancreatic cancer cells through AKT- and ERK-dependent activation of NF-κB pathway

(2015) Nikhil Tyagi et al.   Oncotarget

Activation of nuclear factor κB pathway and downstream targets survivin and livin by SHARPIN contributes to the progression and metastasis of prostate cancer

(2014) Yiming Zhang et al.   CANCER

ERKs in Cancer: Friends or Foes?

(2014) Xavier Deschênes-Simard et al.   CANCER RESEARCH

NF- B Gene Signature Predicts Prostate Cancer Progression

(2014) R. Jin et al.   CANCER RESEARCH

The Proapoptotic Effect of Formononetin in Human Osteosarcoma Cells: Involvement of Inactivation of ERK and Akt Pathways

(2014) Yun Liu et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Coactivation of the PI3K/Akt and ERK signaling pathways in PCB153-induced NF-κB activation and caspase inhibition

(2014) Changjiang Liu et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Recent insights into NF-κB signalling pathways and the link between inflammation and prostate cancer

(2013) Daniel P. Nguyen et al.   BJU INTERNATIONAL

ERK2-dependent reactivation of Akt mediates the limited response of tumor cells with constitutive K-RAS activity to PI3K inhibition

(2013) Mahmoud Toulany et al.   CANCER BIOLOGY & THERAPY

ERK and AKT signaling cooperate to translationally regulate survivin expression for metastatic progression of colorectal cancer

(2013) Q Ye et al.   ONCOGENE

Evading apoptosis in cancer

(2013) Kaleigh Fernald et al.   TRENDS IN CELL BIOLOGY

Cancer treatment and survivorship statistics, 2012

(2012) Rebecca Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

NF-κB and the link between inflammation and cancer

(2012) Joseph A. DiDonato et al.   IMMUNOLOGICAL REVIEWS

Survivin Signaling in Clinical Oncology: A Multifaceted Dragon

(2012) Jagat R. Kanwar et al.   MEDICINAL RESEARCH REVIEWS

LUBAC, a novel ubiquitin ligase for linear ubiquitination, is crucial for inflammation and immune responses

(2012) Fuminori Tokunaga et al.   MICROBES AND INFECTION

Deciphering the rules of programmed cell death to improve therapy of cancer and other diseases

(2011) Andreas Strasser et al.   EMBO JOURNAL

SHARPIN forms a linear ubiquitin ligase complex regulating NF-κB activity and apoptosis

(2011) Fumiyo Ikeda et al.   NATURE

Shank-interacting protein–like 1 promotes tumorigenesis via PTEN inhibition in human tumor cells

(2010) Lizhi He et al.   JOURNAL OF CLINICAL INVESTIGATION

Newly identified tumor-associated role of human Sharpin

(2010) Jinyoung Jung et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Exploitation of protein kinase C: A useful target for cancer therapy

(2008) Ashhar S. Ali et al.   CANCER TREATMENT REVIEWS