Novel platinum(II) complexes containing diaminocyclohexane and thiourea derivative ligands: Synthesis and X-ray crystal structure of (trans-1,2-diaminocyclohexane)dithioureaplatinum(II) nitrate monohydrate

Six novel platinum(II) complexes of the form [Pt(dach)L-2](NO3)(2), where dach = trans-1,2-diaminocyclohexane, L = thiourea (tu) or its derivatives, including 1-acetyl-2-thiourea, 1-ethyl-2-thiourea, 2-imidazolidinethione, 1,3-dimethyl-2-thiourea and 1,1,3,3-tetramethyl-2-thiourea, have been synthesized and characterized by elemental analysis, IR spectrometry, and NMR(H-1 and C-13) spectroscopy. The general synthetic procedure involves the reaction of [Pt(dach)(H2O)(2)](NO3)(2), which is formed in situ by treating Pt(dach)I-2 with silver nitrate, and two equivalents of tu or its derivatives. All the complexes are ionic compounds with nitrate counter ions and thus water soluble. The crystal structure of [Pt(dach)(tu)(2)](NO3)(2) center dot H2O is determined using a single crystal X-ray diffraction method. This compound crystallizes in the orthorhombic space group Pnma with centrosymmetry. (C) 2013 Elsevier B.V. All rights reserved.