Palladium-catalyzed approach to the synthesis of five-membered O-heterocycles

In-recent decades, a large number of reports related to the synthesis of N, O and S containing heterocycles have appeared owing to a wide variety of their biological activity. The metal catalyzed synthesis of heterocycles is becoming an important and highly rewarding protocol in organic synthesis. This review focuses on the use of palladium as a catalyst for the synthesis of oxygen containing five-membered heterocycles. It describes the formation of different types of heterocyclic rings. (C) 2014 Elsevier B.V. All rights reserved.