Article
Sport Sciences
Ra'ad M. Khair, Lauri Stenroth, Annamaria Peter, Neil J. Cronin, Aleksi Reito, Juha Paloneva, Taija Finni
Summary: This study investigated tendon displacement patterns in non-surgically treated patients 14 months after acute Achilles tendon rupture, classifying patients into groups based on their Achilles tendon displacement patterns. Results showed significant differences in tendon displacement patterns between different groups, which may be attributed to anatomical variations and recovery methods.
SCANDINAVIAN JOURNAL OF MEDICINE & SCIENCE IN SPORTS
(2021)
Article
Biophysics
Marion Crouzier, Felix Dandois, Aurelie Sarcher, Stijn Bogaerts, Lennart Scheys, Benedicte Vanwanseele
Summary: The study investigated the impact of horizontal foot position on the subtendons within the Achilles tendon in terms of their length and motion. The results showed that the subtendons had different lengths and motions when the foot was in toes-in or toes-out position. This finding is clinically relevant for pathologies affecting Achilles tendon motion.
JOURNAL OF BIOMECHANICS
(2022)
Article
Physiology
Chloe E. Athaide, Maryia Samuel, Lauren B. L. Jutlah, Carol G. Bryans, Jason S. Au
Summary: This study investigated the impact of external factors such as probe position, neck angle, and breathing on carotid artery longitudinal wall motion (CALM). The results showed that these factors do have an effect on CALM, and it is recommended to scan the carotid artery 1-2 cm proximal to the bifurcation and maintain a neck angle of 70°-90° for accurate data collection.
JOURNAL OF APPLIED PHYSIOLOGY
(2023)
Article
Critical Care Medicine
Daozheng Huang, Feier Song, Bangjun Luo, Shouhong Wang, Tiehe Qin, Zhuandi Lin, Tieying Hou, Huan Ma
Summary: This study evaluated the capability of automatic speckle tracking ultrasound technology in assessing diaphragmatic movement. The results showed a strong correlation between the automatic measurement and manual measurement. The diaphragmatic excursion and velocity measured by speckle tracking could serve as predictive factors for mechanical ventilation weaning failure, prolonged weaning, and in-hospital adverse outcomes.
Article
Medicine, General & Internal
Xiong Ye, Zhi Liu, Ying Ma, Ye Song, Lihua Hu, Jianwen Luo, Hui Xiao
Summary: A novel diaphragm deformation ultrasound imaging method was developed in this study using a NCC algorithm for real-time tracking of right diaphragm movements. Horizontal displacements were greater than vertical displacements, and global strain was found to be insensitive to the imaging plane.
FRONTIERS IN MEDICINE
(2021)
Article
Critical Care Medicine
Florian Ajavon, Fabien Coisy, Laura Grau-Mercier, Jules Fontaine, Antonia Perez Martin, Pierre-Geraud Claret, Xavier Bobbia
Summary: This study aimed to investigate the correlation between femoral arterial diameter variations (fADVs) and stroke volume (SV) during hemorrhagic shock management and resuscitation in anesthetized piglets. The results showed a strong correlation between fADVs and SV.
Article
Medicine, General & Internal
Salvatore De Rosa, Jolanda Sabatino, Antonio Strangio, Isabella Leo, Letizia Rosa Romano, Carmen Anna Spaccarotella, Annalisa Mongiardo, Alberto Polimeni, Sabato Sorrentino, Ciro Indolfi
Summary: This study assessed the usefulness of myocardial work (MW) in the clinical management of patients with severe aortic stenosis (AS) undergoing transcatheter aortic valve implantation (TAVI). The results showed improvements in MW indices after TAVI, but these improvements were less significant in patients with low flow low gradient AS. Therefore, non-invasive MW may be helpful in further classifying AS patients and predicting treatment outcomes.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Optics
Xiaohu Liu, Jiakai Wei, Liangwei Meng, Weimin Cheng, Xuan Zhu, Jinling Lu, Pengcheng Li
Summary: In this study, a method combining a color camera with a non-rigid registration algorithm was proposed to simultaneously image tissue structure and its laser speckle, aiming to improve the motion correction in speckle imaging. Results from animal experiments demonstrate that this method effectively reduces the influence of non-rigid, spatially non-uniform motion on blood flow estimation and enhances the visualization of blood vessels in moving tissue, thus promoting the practical application of LSCI technology.
OPTICS AND LASERS IN ENGINEERING
(2021)
Article
Optics
Yaoyao Shi, Youwen Liu, Wei Sheng, Dabo Zhu
Summary: A method for non-invasive imaging and tracking of moving and changing objects hidden behind scattering layers from a single multiplexed speckle is proposed, which involves detecting speckles at different moments, numerically rotating them, and multiplexing them in a single speckle.
OPTICS COMMUNICATIONS
(2021)
Article
Biophysics
Patrick A. Jones, John S. Wilson
Summary: An improved aortic DENSE MRI postprocessing method was proposed to evaluate the feasibility of quantifying all components of the 2D strain tensor. The new method revealed significant differences in regional CS and increased magnitudes of regional RSS, with minimal impact on CS repeatability. However, the repeatability metrics for RSS were worse than for CS, indicating the need for further studies to improve repeatability and assess partial volume effects.
JOURNAL OF BIOMECHANICAL ENGINEERING-TRANSACTIONS OF THE ASME
(2021)
Article
Engineering, Electrical & Electronic
David Weik, Richard Nauber, Christian Kupsch, Lars Buettner, Juergen Czarske
Summary: This study introduces a novel method for estimating the uncertainty of a specific experimental setup according to the guide to the expression of uncertainty in measurement (GUM), based on an uncertainty model of the UIV processing. The proposed model provides optimal parameterization of UIV and velocity uncertainty for a specific experiment. Experimental validation demonstrates the feasibility and effectiveness of this method in MHD experiments.
IEEE TRANSACTIONS ON INSTRUMENTATION AND MEASUREMENT
(2021)
Article
Obstetrics & Gynecology
Inge P. M. Jordans, Jolijn Vissers, Yizhou Huang, Massimo Mischi, Dick Schoot, Judith A. F. Huirne
Summary: In a prospective cohort study conducted in a Dutch medical centre, it was found that women with a niche in the uterine caesarean section scar had significantly higher amplitude of subendometrial contractions compared to women without a caesarean section scar during all phases of the menstrual cycle. The velocity of contractions was lower in women with a niche only during the late follicular phase. Furthermore, there was a positive correlation between the size of the niche and the amplitude of subendometrial contractions.
REPRODUCTIVE BIOMEDICINE ONLINE
(2023)
Article
Critical Care Medicine
Jieqiong Song, Yao Yao, Shilong Lin, Yizhou He, Duming Zhu, Ming Zhong
Summary: TMAD is a novel and feasible technology with promising discriminatory value for predicting SICM and mortality in sepsis cases.
Article
Biochemistry & Molecular Biology
Mateusz Olek, Kevin Cowtan, Donovan Webb, Yuriy Chaban, Peijun Zhang
Summary: Despite the abundance of software tools, optimal particle selection remains a crucial issue in cryo-EM. IceBreaker is introduced as a valuable tool that estimates and equalizes the relative ice gradient, allowing differentiation of particles and improving selection performance. The software also introduces a parameter for local ice thickness, enabling particle grouping and filtering based on this parameter.
Article
Cardiac & Cardiovascular Systems
Cathleen R. Pruitt, Shaji Menon, Ashwin K. Lal, Aaron W. Eckhauser, Zhining Ou, Angela Presson, Thomas Miller, Mary Niu
Summary: This study evaluated the association between 2D-STE and arrhythmias in children with acute myocarditis, finding that global and regional strain indices were reduced in the arrhythmia group, particularly in the basal and mid segments. The findings suggest that echocardiographic LV deformation by 2D-STE may be useful in identifying pediatric patients at risk for arrhythmias.
AMERICAN JOURNAL OF CARDIOLOGY
(2021)
Article
Engineering, Biomedical
Jonathon L. Blank, Darryl G. Thelen, Joshua D. Roth
JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS
(2020)
Article
Geriatrics & Gerontology
Anahid Ebrahimi, Isaac F. Loegering, Jack A. Martin, Robin L. Pomeroy, Joshua D. Roth, Darryl G. Thelen
EXPERIMENTAL GERONTOLOGY
(2020)
Article
Orthopedics
Isaac F. Loegering, Sarah C. Denning, Kevin M. Johnson, Fang Liu, Kenneth S. Lee, Darryl G. Thelen
Summary: Older Achilles tendons have lower bound water fraction, longer transverse relaxation times, and thicker tendons compared to younger tendons, indicating early signs of sub-clinical tendinopathy.
SKELETAL RADIOLOGY
(2021)
Article
Biophysics
Mitchell G. A. Wheatley, Allison L. Clouthier, Darryl G. Thelen, Michael J. Rainbow
Summary: The relationship between three-dimensional shape and patellofemoral mechanics is complex, with Wiberg patella classification used to connect shape differences to observed mechanics. Different Wiberg patella types have varying influences on force distribution within the patellofemoral joint, with type III patellas showing a sharper patella apex and lower ratios of quadriceps tendon forces to patellar ligament forces. This study provides insights into how patella morphology affects patellar mechanics and may aid in identifying at-risk populations for pathology development.
JOURNAL OF BIOMECHANICAL ENGINEERING-TRANSACTIONS OF THE ASME
(2021)
Article
Neurosciences
Anahid Ebrahimi, Robyn L. Kuchler, Robin L. Pomeroy, Isaac F. Loegering, Jack A. Martin, Darryl G. Thelen
Summary: This study is the first to utilize shear wave tensiometry to characterize Achilles and patellar tendon loading during gait in children. Achilles tendon loading closely aligns with peak ankle plantarflexor moment during push-off, while patellar tendon loading increases with walking speed and matches peak knee extension moment timings.
Article
Engineering, Biomedical
Allison L. Clouthier, Daniel Borschneck, Colin R. Smith, Michael F. Vignos, Darryl G. Thelen, Kevin J. Deluzio, Michael J. Rainbow
Summary: This study used statistical shape modeling and musculoskeletal simulation to investigate the effect of patellofemoral geometry on the relationship between tibial tubercle location and patellofemoral function. The results showed that the trochlear geometry had a significant impact on tubercle medialization, patella position, and cartilage contact pressure.
JOURNAL OF APPLIED BIOMECHANICS
(2022)
Article
Engineering, Biomedical
Jonathon L. Blank, Darryl G. Thelen, Matthew S. Allen, Joshua D. Roth
Summary: The study aimed to investigate the impact of material properties and fiber alignment on shear wave propagation speed, finding a strong correlation between shear wave speed and tissue density, and suggesting that shear wave speed likely increases in response to a load-dependent increase in the apparent shear modulus.
JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS
(2022)
Article
Chemistry, Analytical
Sara E. Harper, Dylan G. Schmitz, Peter G. Adamczyk, Darryl G. Thelen
Summary: This study combines kinetic and kinematic measures to establish a wearable system for estimating work and power output from the soleus and gastrocnemius muscles during outdoor locomotion. Results show that gastrocnemius work is relatively insensitive to incline, while soleus work scales with incline.
Article
Orthopedics
Anahid Ebrahimi, Michael H. Schwartz, Jack A. Martin, Tom F. Novacheck, Darryl G. Thelen
Summary: The purpose of this study was to evaluate the mechanical behavior of the Achilles tendon during gait in children with cerebral palsy (CP) using a noninvasive sensor. The results showed that children with CP had significantly reduced Achilles tendon work compared to typically developing children. The work loop patterns in CP children were different from those in the control group, indicating a different muscle-tendon behavior.
JOURNAL OF ORTHOPAEDIC RESEARCH
(2022)
Article
Chemistry, Analytical
Dylan G. Schmitz, Darryl G. Thelen, Stephanie G. Cone
Summary: This study investigates the use of a Kalman filter and redundant accelerometers to improve the accuracy and robustness of shear wave tensiometry in measuring tendon wave speed. The results show that the Kalman filter significantly improves the accuracy of estimated wave speeds, and increasing the number of accelerometers and using redundant accelerometers further reduce wave speed errors and improve the robustness of wave speed measures.
Article
Orthopedics
Matthew B. Blomquist, Jonathon L. Blank, Dylan G. Schmitz, Darryl G. Thelen, Joshua D. Roth
Summary: This study aimed to investigate the capability of shear wave tensiometry in detecting changes in ligament tension following incremental releases. The results showed that shear wave tensiometry can measure the tension reduction in released structures objectively. This has clinical significance in enhancing surgical precision during soft tissue balancing in total knee arthroplasty.
JOURNAL OF ORTHOPAEDIC RESEARCH
(2023)
Article
Robotics
Dylan G. Schmitz, Richard W. Nuckols, Sangjun Lee, Tunc Akbas, Krithika Swaminathan, Conor J. Walsh, Darryl G. Thelen
Summary: Exosuits have the potential to assist locomotion in both healthy and pathological populations, but their effect on muscle-tendon loading is not yet fully understood. This study used shear wave tensiometers to measure Achilles tendon force and found that ankle exosuit assistance reduced peak Achilles tendon force. The relationship between tendon force and ankle torque was no longer significant when ankle plantarflexor assistance was applied.
Article
Radiology, Nuclear Medicine & Medical Imaging
Scott K. Crawford, Darryl Thelen, Janice M. Yakey, Bryan C. Heiderscheit, John J. Wilson, Kenneth S. Lee
Summary: In patients with Achilles tendinopathy, traditional sonographic measures showed increased tendon thickness, hyperemia, and hypoechogenicity in the symptomatic tendon compared to the contralateral side. However, lower shear wave speed (SWS) was observed only in the free tendon, indicating localized alterations in tendon elasticity associated with Achilles tendinopathy.
EUROPEAN RADIOLOGY
(2023)
Article
Clinical Neurology
Samuel A. Acuna, Mitchell E. Tyler, Darryl G. Thelen
Summary: This study investigated the neuromuscular complexity during gait in individuals with chronic balance deficits caused by a prior traumatic brain injury (TBI). The results showed decreased neuromuscular complexity in individuals with a prior TBI compared to controls. The individuals exhibited slower walking speeds, reduced performance on the Dynamic Gait Index, and altered control of the temporal activation of muscle synergies.
NEUROREHABILITATION AND NEURAL REPAIR
(2022)
Article
Multidisciplinary Sciences
Mitchell G. A. Wheatley, Darryl G. Thelen, Kevin J. Deluzio, Michael J. Rainbow
Summary: The study showed that there are differences in moment arms of the knee joint during walking and running, which are related to knee flexion and motion direction. The high inter-subject variation in moment arms is mainly explained by out-of-plane motion.
JOURNAL OF THE ROYAL SOCIETY INTERFACE
(2021)
