Article
Oncology
Kritika Prasai, Sri Harsha Tella, Siddhartha Yadav, Anuhya Kommalapati, Kristin Mara, Mohamed Mady, Mohamed A. Hassan, Nicha Wongjarupong, Natalia Rodriguez-Payan, Mitesh Borad, Tushar Patel, Lewis R. Roberts, Amit Mahipal
Summary: The study demonstrated that the use of aspirin alone or in combination with statins is strongly associated with a reduced risk of gallbladder cancer (GBC). Further prospective studies are needed to confirm these results and elucidate their mechanisms.
Article
Ophthalmology
Manal Alwazae, Atheer Alhumud, Abdulrahman Aldarrab, Abdullah Bin Hemid, Razan Abu AlHassan, Fadwa AlAdel, Leyla Aljasim, Ohoud Owaidha
Summary: This study aimed to evaluate the impact of using a decision aid tool on patients with open-angle glaucoma. The results showed that using the decision aid tool significantly improved patients' knowledge and medication adherence.
EUROPEAN JOURNAL OF OPHTHALMOLOGY
(2023)
Review
Gastroenterology & Hepatology
Myung Ji Goh, Dong Hyun Sinn
Summary: This review summarizes the potential therapeutic applications of aspirin and statins as chemopreventive agents for hepatocellular carcinoma (HCC). The authors emphasize the limitations of observational data and the need for further clinical investigations.
CLINICAL AND MOLECULAR HEPATOLOGY
(2022)
Article
Business
Crystal Reeck, Nathaniel A. Posner, Kellen Mrkva, Eric J. Johnson
Summary: The authors find that inexpensive choice architecture techniques, such as manipulating choice sequence, color, and wording, can significantly increase smartphone app adoption. Integrating multiple feature decisions into a single choice decreases decision noise and increases adoption. Changing colors to match habitual patterns and wording options as if enabling the app is the default response also contribute to increased adoption. These findings are applicable to different types of apps and are robust across different demographics, attitudes, and political affiliations.
JOURNAL OF MARKETING
(2023)
Article
Public, Environmental & Occupational Health
Guofang Ye, Bo Qu, Yih-Chung Tham, Yuxin Zhong, Ling Jin, Ecosse Lamoureux, Nathan Congdon, Yingfeng Zheng, Yizhi Liu
Summary: The study found that using a patient decision aid can increase the proportion of patients making informed choices, improve their overall knowledge about cataract surgery, and reduce the intention to undergo surgery.
PATIENT EDUCATION AND COUNSELING
(2021)
Article
Geriatrics & Gerontology
Taeho Greg Rhee, Manish Kumar, Joseph S. Ross, Patrick P. Coll
Summary: The study found that the prevalence of adults eligible for primary and secondary prevention treatment of cardiovascular diseases significantly increased with age. The use of low-dose aspirin and statins also increased with age, especially among adults aged 75 and older. Further education and guidance on the appropriate use of aspirin and statins for preventing cardiovascular diseases is needed for healthcare providers and older adults.
JOURNAL OF THE AMERICAN GERIATRICS SOCIETY
(2021)
Article
Urology & Nephrology
Romy E. D. Lamers, Maarten Cuypers, Marieke de Vries, Lonneke V. Van de Poll-Franse, J. L. H. Ruud Bosch, Paul J. M. Kil
Summary: In this study, patients using decision aids were more likely to choose active surveillance as a treatment option, while patients not using decision aids were more likely to choose brachytherapy as a treatment option.
WORLD JOURNAL OF UROLOGY
(2021)
Article
Public, Environmental & Occupational Health
Amanda S. Freed, Inga Gruss, Carmit K. McMullen, Michael C. Leo, Tia L. Kauffman, Kathryn M. Porter, Kristin R. Muessig, Donna Eubanks, Katrina A. B. Goddard, Benjamin S. Wilfond, Elizabeth G. Liles
Summary: The study describes the development of a web-based decision aid to assist patients and research participants in making informed, values-based decisions about receiving additional results from genomic sequencing. The decision aid, called ORCA, was found to be highly readable and relevant in alpha testing, supporting informed decision making.
PATIENT EDUCATION AND COUNSELING
(2021)
Review
Public, Environmental & Occupational Health
Kelly E. Lloyd, Louise H. Hall, Natalie King, Rachael J. Thorneloe, Rocio Rodriguez-Lopez, Lucy Ziegler, David G. Taylor, Mairead MacKenzie, Samuel G. Smith
Summary: The systematic review synthesized data on attitudes and behavior towards the use of aspirin for cancer prevention, as well as healthcare providers' attitudes towards implementing aspirin in practice. Eligible users of aspirin showed moderate to high willingness to participate in trials evaluating aspirin for preventive therapy, with high day-to-day adherence among trial participants. Healthcare providers generally perceived aspirin as a suitable option for cancer prevention.
PREVENTIVE MEDICINE
(2022)
Article
Oncology
Mayuko Ito Fukunaga, Akshu Balwan, Jaclyn A. Janis, Caitlin Gutheil, Jason Yahwak, Paul K. J. Han
Summary: The study found that in-person shared decision-making counseling for lung cancer screening is feasible and effective in reducing patient decision conflict. However, further research is needed to determine the independent effects of decision aids, and future efforts to promote shared decision-making may need to focus on improving patient understanding of the benefits of screening.
JOURNAL OF CANCER EDUCATION
(2022)
Article
Oncology
Sandrine Hild, Delphine Teigne, Emilie Ferrat, Anne-Sophie Banaszuk, Karine Berquet, Aline Lebon, Emmanuelle Bataille, France Nanin, Aurelie Gaultier, Cedric Rat
Summary: This article presents a protocol to evaluate the effect of a decision aid on participation rates in the French organized breast cancer screening program. The study design is a 2 arm randomized controlled study, performed in the Pays de la Loire region. The study aims to demonstrate that providing a better explanation of the benefits and risks of breast cancer screening can increase participation rates and inform future implementation of shared medical decision-making.
FRONTIERS IN ONCOLOGY
(2023)
Article
Gastroenterology & Hepatology
Yin Zhang, Kana Wu, Andrew T. Chan, Jeffrey A. Meyerhardt, Edward L. Giovannucci
Summary: This study aims to investigate the relationship between statin use and the risk of colorectal cancer. The study found that long-term use of statins may increase the risk of colon cancer.
AMERICAN JOURNAL OF GASTROENTEROLOGY
(2022)
Review
Oncology
Seung In Seo, Chan Hyuk Park, Tae Jun Kim, Chang Seok Bang, Jae Young Kim, Kyung Joo Lee, Jinseob Kim, Hyon Hee Kim, Seng Chan You, Woon Geon Shin
Summary: The study found that the use of statin and aspirin was associated with significantly reduced risks of gastric cancer development, while the use of metformin was not associated with gastric cancer risk. Use of statin in diabetic patients can significantly reduce the risk of gastric cancer development. The meta-analysis showed that statin had the highest effect size on gastric cancer development, followed by aspirin and metformin.
Article
Medical Informatics
Lenira Semedo, Kate J. Lifford, Adrian Edwards, Kathy Seddon, Kate Brain, Stephanie Smits, Sunil Dolwani
Summary: The study aimed to develop a decision aid to help individuals make informed decisions about using aspirin to reduce colorectal cancer risk. Participants found the decision aid acceptable and useful, expressing a need for personalized risk information and more detail on the potential risks of aspirin.
BMC MEDICAL INFORMATICS AND DECISION MAKING
(2021)
Article
Gastroenterology & Hepatology
Jasleen Singh, Amy Wozniak, Scott J. Cotler, Asha Dhanarajan, Daniel Aldrich, David Park, Chris Kasia, Benjamin Schmidt, Steven Scaglione
Summary: This study suggests that daily use of aspirin (ASA) is associated with a decreased risk of hepatocellular carcinoma (HCC), and the combination of ASA and statin use further reduces the risk of HCC. Additionally, there is no significant increase in the risk of esophageal variceal hemorrhage (VH) among daily ASA users compared with non-users.
JOURNAL OF CLINICAL GASTROENTEROLOGY
(2022)
Article
Pharmacology & Pharmacy
Laney K. Jones, Vanessa Hayduk, Katrina M. Romagnoli, Alison Flango, Jami Marks, Jove Graham, Michael R. Gionfriddo
Summary: This study examines the implementation of a medication reconciliation educational program and its impact on clinic personnel knowledge and practice. The results show that the program was widely implemented and considered acceptable and appropriate, although adaptations were made to fit specific clinic needs.
JOURNAL OF THE AMERICAN PHARMACISTS ASSOCIATION
(2022)
Editorial Material
Medicine, General & Internal
Kasey R. Boehmer, Katie Gallacher, Kate A. Lippiett, Frances S. Mair, Carl R. May, Victor M. Montori
MAYO CLINIC PROCEEDINGS
(2022)
Article
Public, Environmental & Occupational Health
Marleen Kunneman, Ian G. Hargraves, Angela L. Sivly, Megan E. Branda, Christina M. LaVecchia, Nanon H. M. Labrie, Sarah Brand-McCarthy, Victor Montori
Summary: By analyzing the impact of the use of a within-encounter SDM tool on the sensibility of care plans for patients with atrial fibrillation, it was found that the sensibility of the plans was similar in both groups, and it was weakly correlated with decisional conflict but not with patient involvement or adherence. Most patients found their care plans sensible based on known efficacy, safety, and implementation factors.
PATIENT EDUCATION AND COUNSELING
(2022)
Review
Toxicology
Noah S. Ball, Brittany M. Knable, Taylor A. Relich, Allyson N. Smathers, Michael R. Gionfriddo, Branden D. Nemecek, Courtney A. Montepara, Anthony J. Guarascio, Jordan R. Covvey, David E. Zimmerman
Summary: The exposure to Xylazine in humans is on the rise and poses a concern in prehospital and emergency medicine settings. However, there is a lack of standardized treatment algorithm and further research is needed to improve the care of patients exposed to Xylazine.
CLINICAL TOXICOLOGY
(2022)
Review
Pharmacology & Pharmacy
Riyan Babidhan, Abigale Lewis, Cailin Atkins, Nicolas J. Jozefczyk, Branden D. Nemecek, Courtney A. Montepara, Michael R. Gionfriddo, David E. Zimmerman, Jordan R. Covvey, Anthony J. Guarascio
Summary: This systematic review examines the safety and efficacy of off-label use of cefiderocol for various infections, particularly for Pseudomonas aeruginosa and Acinetobacter baumannii infections. Combination antibiotic therapy was commonly used, and cefiderocol-related side effects were rare.
Article
Health Care Sciences & Services
Victor M. Montori, Merel M. Ruissen, Megan E. Branda, Ian G. Hargraves, Marleen Kunneman
Summary: This study aims to evaluate the implementation of shared decision making (SDM) in clinical encounters and across different SDM forms. The findings suggest that the prescribed steps of SDM are rarely followed in order, regardless of whether an SDM intervention was used. There is no clear pattern of steps that distinguishes among different SDM forms.
HEALTH EXPECTATIONS
(2023)
Editorial Material
Medicine, General & Internal
Victor Montori, Marleen Kunneman
BMJ EVIDENCE-BASED MEDICINE
(2023)
Editorial Material
Medicine, General & Internal
Victor M. Montori, Merel M. Ruissen, Ian G. Hargraves, Juan P. Brito, Marleen Kunneman
BMJ EVIDENCE-BASED MEDICINE
(2023)
Review
Health Care Sciences & Services
Marleen Kunneman, Derek Gravholt, Sandra A. Hartasanchez, Michael R. Gionfriddo, Zoe Paskins, Larry J. Prokop, Anne M. Stiggelbout, Victor M. Montori
Summary: This study aimed to summarize instruments capable of measuring dimensions of patient-clinician collaboration to make care fit. The researchers systematically searched several databases and included 189 relevant papers. The results showed that existing measures of making care fit focus heavily on the content and manner of patient-clinician collaboration, while neglecting other crucial dimensions and actions.
HEALTH EXPECTATIONS
(2023)
Letter
Medicine, General & Internal
Loai Albarqouni, Victor Montori, Karsten Juhl Jorgensen, Martin Ringsten, Helen Bulbeck, Minna Johannson
BMJ EVIDENCE-BASED MEDICINE
(2023)
Article
Medicine, General & Internal
Merel M. Ruissen, Victor M. Montori, Ian G. Hargraves, Megan E. Branda, Montserrat Leon Garcia, Eelco J. P. de Koning, Marleen Kunneman
Summary: This study aimed to describe the collaborative approaches to shared decision-making (SDM) in clinical encounters of patients with diabetes and their clinicians. The findings showed that at least one instance of SDM was observed in 86 out of 100 encounters, with varying forms of SDM present. Weighing alternatives, negotiating conflicting desires, and problemsolving were the most common forms of SDM observed. The study also found a correlation between the form of SDM focused on weighing alternatives and higher patient involvement. Overall, recognizing the different forms of SDM used by clinicians and patients opens new possibilities for research and practice in patient-centered care.
BMJ EVIDENCE-BASED MEDICINE
(2023)
Review
Pharmacology & Pharmacy
Michael R. Gionfriddo, Katelyn M. Owens, Sarah E. Leist, Luke T. Schrum, Jordan R. Covvey
Summary: Community pharmacy staff have knowledge regarding the benefits of OTC syringes, but personal attitudes and beliefs heavily influence decisions to engage in sales. Despite support for various syringe-related harm reduction activities, offerings of services were less likely due to concerns around people who inject drugs (PWID).
JOURNAL OF THE AMERICAN PHARMACISTS ASSOCIATION
(2023)
Article
Social Sciences, Interdisciplinary
Michael R. Gionfriddo, Ann Dadich
Summary: This article explores the impact of the COVID-19 pandemic on researchers using video-reflexive ethnography (VRE). The findings suggest that the pandemic exacerbated methodological challenges and provided opportunities for self-reflection. Researchers had to rely on insiders to access research sites, which empowered participants but also hindered relationship-building. Reflexive sessions were challenged by technological and logistical difficulties. Digital methodologies increased project reach but required mindfulness towards care practices and data protection.
INTERNATIONAL JOURNAL OF QUALITATIVE METHODS
(2023)
Review
Endocrinology & Metabolism
Alejandra Meza-Contreras, Camila Wenczenovicz, Kim Ruiz-Arellanos, Elissa A. Kinzelman Vesely, Renzo Mogollon, Victor M. Montori
Summary: This systematic review examined 26 articles on expert recommendations for statin intolerance, revealing substantial variability in the definition and management approaches. Most experts provided management suggestions, but lacked supporting evidence. Few experts focused on reducing atherosclerotic cardiovascular disease (ASCVD) risk, and none promoted shared decision making with patients.
Article
Pharmacology & Pharmacy
Allison N. Hamner, Benjamin Andrick, Anupama Mathur, Michael R. Gionfriddo
Summary: This study investigated patients' perceptions of the role and benefits of pharmacists in their care. The results showed that patients valued the services provided by pharmacists in the oral chemotherapy clinic. However, areas of improvement were identified, including the clarity of communication and the pharmacist's role in the care team.
JOURNAL OF THE AMERICAN COLLEGE OF CLINICAL PHARMACY
(2023)
