Article
Chemistry, Analytical
Zhen Luo, Weiqing Xu, Zhichao Wu, Lei Jiao, Xin Luo, Mengzhen Xi, Rina Su, Liuyong Hu, Wenling Gu, Chengzhou Zhu
Summary: The Ru(bpy)(3)(2+)-tripropylamine ECL system is widely used in commercial bioanalysis, but the presence of amines in the biological environment causes unwanted anodic interference signals. To overcome this, a cathodic Ru(bpy)(3)(2+) ECL system is proposed, which utilizes the iron-nitrogen-carbon catalyst to activate the ECL signal. This innovative system shows great potential for practical applications, demonstrated by the successful development of an ECL biosensor for detecting alkaline phosphatase activity.
ANALYTICAL CHEMISTRY
(2023)
Article
Chemistry, Analytical
Xianzhen Song, Tingting Wu, Chuannan Luo, Lu Zhao, Xiang Ren, Yong Zhang, Qin Wei
Summary: The study developed a highly efficient biosensor for neuron-specific enolase (NSE) detection using Ag NCs as signal probes and Pd-Cu2O hybrid nanoconcaves as coreaction promoters. By controlling the reversible cycle of Cu+/Cu2+ and the reduction characteristics of Pd NPs, Pd-Cu2O accelerated the reduction of S2O82- and promoted the generation of active intermediates (OH center dot) to enhance the sensitivity of the biosensor. Additionally, the introduction of a short peptide ligand (NARKFYKGC, NFC) improved the binding efficiency of antibodies and protected their bioactivity, thus significantly enhancing the biosensor's sensitivity.
ANALYTICAL CHEMISTRY
(2021)
Article
Chemistry, Physical
Kenneth Chu, Jonathan R. Adsetts, Jing Ma, Congyang Zhang, Mahdi Hesari, Liuqing Yang, Zhifeng Ding
Summary: In this study, an absolute method using a photon-counting device was developed to determine the electrochemiluminescence quantum efficiency of coreactant systems. The efficiency of the Ru(bpy)(3)(2+)/ tri-n-propylamine (TPrA) ECL coreactant system was found to be 10.0 +/- 1.1%, showing a 3-fold enhancement compared to annihilation pathways. These findings suggest a promising approach in the expanding field of ECL research.
JOURNAL OF PHYSICAL CHEMISTRY C
(2021)
Article
Chemistry, Analytical
Maoding Zuo, Lin Cui, Shuangwen Wang, Wengui Wei, Wenqiang Gao, Chun-yang Zhang
Summary: In this study, an exogenous coreactant-free electrochemiluminescent sensor based on a hydrazone-linked COF was developed for glucose sensing. The sensor showed good selectivity, stability, and high sensitivity with a LOD of 0.031 mu M, and it accurately detected glucose in human serum.
Article
Chemistry, Analytical
Li Fu, Xiancheng Liu, Ying Zeng, Qingqing Zhang, Bin Zhang, Xuwen Gao, Guizheng Zou
Summary: A promising ECL immunoassay strategy is proposed in this study, which utilizes biocompatible nanoparticles as the luminophore and achieves coreactant-free near-infrared ECL processes through electrochemical oxidation. This method exhibits high sensitivity and accuracy in the detection of tumor markers.
ANALYTICAL CHEMISTRY
(2022)
Article
Chemistry, Analytical
Xin-Tao Wang, Yi-Rong Jiang, Li-Yan Huang, Yi-Xin Gu, Xiao-Qin Huang, Ai-Jun Wang, Pei-Xin Yuan, Jiu-Ju Feng
Summary: Metal-organic frameworks were used to enhance the ECL responses of N-(aminobutyl)-N-(ethylisoluminol) and develop a high-performance ECL biosensor for the detection of chloramphenicol.
Article
Chemistry, Analytical
Xianzhen Song, Lu Zhao, Nuo Zhang, Lei Liu, Xiang Ren, Hongmin Ma, Xuan Kuang, Yuyang Li, Chuannan Luo, Qin Wei
Summary: A high-efficiency biosensor based on a ternary electrochemiluminescence system was developed for procalcitonin (PCT) detection. Silver nanoclusters (Ag NCs) with stable luminescence properties were prepared using lipoic acid (LA) as the ligand, and their electrochemiluminescence in persulfate (S2O82-) was reported for the first time. The addition of alpha-Fe2O3-Pt facilitated the activation of S2O82-, enhancing the electrochemiluminescence emission of Ag NCs. The biosensor showed high sensitivity for PCT detection with a wide linear range and low detection limit.
ANALYTICAL CHEMISTRY
(2023)
Article
Chemistry, Analytical
Jie-Kang Tian, Mei-Ling Zhao, Yu-Meng Song, Xia Zhong, Ruo Yuan, Ying Zhuo
Summary: A new field-free and highly ordered spherical nucleic acid (SNA) nanostructure was self-assembled using ferrocene-labeled DNA tweezers and DNA linkers, serving as an ECL switch for improved recognition efficiency. Combined with mesoporous silica nanospheres (mSiO(2) NSs) filled with Rub-Pt nanoparticles (Rub-Pt@mSiO(2) NSs), a highly sensitive detection platform for let-7b microRNA was achieved through target-triggered SNA deconstruction, highlighting potential applications in biomarker analyses.
ANALYTICAL CHEMISTRY
(2021)
Article
Chemistry, Analytical
Wei Huang, Gui-Bing Hu, Wen-Bin Liang, Jun-Mao Wang, Mei-Ling Lu, Ruo Yuan, Dong-Rong Xiao
Summary: By developing a new hydrothermal etching strategy, a hollow hierarchical MOF with a hierarchical-pore shell was fabricated and used as a carrier to graft Ru(bpy)(2)(mcpbpy)(2+), resulting in the HH-Ru-UiO-66-NH2 with impressive ECL emission. The novel HH-Ru-UiO-66-NH2 showed enhanced ECL performance due to its unique structure and efficient loading of luminophores.
ANALYTICAL CHEMISTRY
(2021)
Article
Chemistry, Analytical
Xuwen Gao, Xiaoxuan Ren, Yaojia Ai, Mengwei Li, Bin Zhang, Guizheng Zou
Summary: This study proposes a coreactant-free electrochemiluminescence method using mercaptopropionic acid and hexametaphosphate as the capping agents. The method achieves low-triggering-potential and coreactant-free electrochemiluminescence. The method is used for the sensitive and selective determination of molecular protein ProGRP.
ANALYTICAL CHEMISTRY
(2023)
Article
Chemistry, Multidisciplinary
Hyun Seung No, Jong-In Hong
Summary: This study reports a new electrochemiluminescence (ECL) probe based on a cyclometalated iridium complex for the selective detection of formaldehyde. By undergoing a functional group transformation, the iridium complex exhibits significant changes in electronic properties and molecular orbital energies, leading to enhanced ECL and radiometric phosphorescence changes. The energetic requirements for ECL sensing were investigated, and the sensing mechanism was elucidated using spectroscopic analysis.
Article
Chemistry, Analytical
Yue Zhang, Jia-Hang Li, Xiao-Long Zhang, Hai-Jun Wang, Ruo Yuan, Ya-Qin Chai
Summary: Due to effective tackling of aggregation-caused quenching of traditional ECL emitters, aggregation-induced electrochemiluminescence (AIECL) has emerged as a research hotspot in aqueous detection and sensing. However, existing AIECL emitters still face challenges of low efficiency, poor biocompatibility, and high cost. In this study, aluminum(III)-based organic nanofibrous gels (AOGs) are used as a novel AIECL emitter to construct a rapid and ultrasensitive sensing platform for detecting Flu A virus biomarker DNA (fDNA) with the assistance of a high-speed and hyper-efficient signal magnifier, a rigid triplex DNA walker (T-DNA walker). The proposed AOGs exhibit efficient ECL response, outstanding biocompatibility, and the on-off ECL biosensor shows a low detection limit for target fDNA, providing a useful platform for rapid and sensitive monitoring of biomolecules and expanding potential applications in molecular devices, clinical diagnosis, and sensing analysis.
ANALYTICAL CHEMISTRY
(2023)
Article
Chemistry, Analytical
Guolin Hong, Canping Su, Zhongnan Huang, Quanquan Zhuang, Chaoguo Wei, Haohua Deng, Wei Chen, Huaping Peng
Summary: The study introduced a dual-function ECL probe IgG-AuNCs for the development of a high-performance ECLIA platform. It was successfully applied for IgG detection, demonstrating features such as easy preparation, rapid detection, sample saving, and high selectivity.
ANALYTICAL CHEMISTRY
(2021)
Article
Chemistry, Multidisciplinary
Hang Gao, Jia-Bao Lin, Shu-Min Wang, Qian-Qian Tao, Ben-Zhong Tang, Hong-Yuan Chen, Jing-Juan Xu
Summary: For the first time, the aggregation-induced electrochemiluminescence (AIECL) phenomenon of organic dots in aqueous media is reported, with near-infrared II (NIR-II) luminescence at 906 nm. A hybrid mechanism of ECL generation is revealed through experiments and calculations. This work opens up new possibilities for exploring efficient organic dye-based NIR-II AIECL emitters.
CHEMICAL COMMUNICATIONS
(2023)
Article
Chemistry, Multidisciplinary
Sopon Butcha, Jing Yu, Zikkawas Pasom, Bertrand Goudeau, Chularat Wattanakit, Neso Sojic, Alexander Kuhn
Summary: Chiral-imprinted mesoporous Pt-Ir alloy surfaces combined with electrochemiluminescence can detect the two enantiomers of phenylalanine, producing significant signal differences. The chiral features of the metal surfaces are converted into enantioselective electrogeneration of dye excited states, resulting in different light emission intensities.
CHEMICAL COMMUNICATIONS
(2022)
Article
Materials Science, Multidisciplinary
Lvlv Ji, Huifang Zheng, Yujie Wei, Shuaiqi Gong, Tao Wang, Sheng Wang, Zuofeng Chen
Summary: Through a temperature-controlled strategy, researchers have successfully prepared bimetallic Co-Fe phosphide nanoframes with a skeletal hollow structure, providing more accessible active sites and channels, exhibiting excellent catalytic activity for oxygen evolution reaction.
SCIENCE CHINA-MATERIALS
(2022)
Article
Chemistry, Multidisciplinary
Lok-Kwan Li, Cathay Chai Au-Yeung, Man-Chung Tang, Shiu-Lun Lai, Wai-Lung Cheung, Maggie Ng, Mei-Yee Chan, Vivian Wing-Wah Yam
Summary: A new class of yellow- to red-emitting carbazolylgold(iii) complexes with high photoluminescence quantum yields has been designed and synthesized, showing improved operational lifetimes in organic light-emitting devices. This work provides insights into the development of robust and highly luminescent gold(iii) complexes and stable molecular motifs for designing efficient emitters.
MATERIALS HORIZONS
(2022)
Correction
Nanoscience & Nanotechnology
Chuangjun Liu, Lihua Zhou, Fangfang Wei, Ling Li, Shunan Zhao, Ping Gong, Lintao Cai, Keith Man-Chung Wong
ACS APPLIED MATERIALS & INTERFACES
(2022)
Article
Chemistry, Multidisciplinary
Jenny Yuk-Wa Yeung, Fred Ka-Wai Kong, Franky Ka-Wah Hau, Michael Ho-Yeung Chan, Maggie Ng, Ming-Yi Leung, Vivian Wing-Wah Yam
Summary: A series of platinum(II) calix[4]arene-based molecular tweezers were synthesized, and their host-guest association with a charge-neutral cyclometalated platinum(II) complex was studied. The experiments showed that changing the solvent composition could control the assembly process, resulting in the formation of high-ordered host-guest oligomers. The change in assembly behaviors could be detected through drastic color changes.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2022)
Article
Chemistry, Inorganic & Nuclear
Chi-Ho Lam, Wai Kit Tang, Vivian Wing-Wah Yam
Summary: In this study, a novel tetranuclear copper(I) complex was designed and synthesized, which exhibited intense and long-lived phosphorescence in the solid and solution states. The complex showed strong reducing power in the excited state, as demonstrated by oxidative quenching studies. Additionally, the transient absorption difference spectrum analysis revealed characteristic absorption and intervalence charge-transfer transitions in the complex.
INORGANIC CHEMISTRY
(2022)
Article
Chemistry, Inorganic & Nuclear
Tony Ho-Ching Fung, Maggie Ng, Nathan Man-Wai Wu, Vivian Wing-Wah Yam
Summary: A series of cyclometalated platinum(II) complexes with a dithienylethene-containing N^C and an ancillary O^O ligand have been synthesized and characterized. These complexes exhibit photochromism that can be triggered by photoexcitation and their photophysical and photochromic properties can be tuned by varying the ligands. Moreover, the complexes demonstrate fatigue resistance and thermal irreversibility, making them promising candidates for various applications.
EUROPEAN JOURNAL OF INORGANIC CHEMISTRY
(2022)
Article
Chemistry, Multidisciplinary
Liang-Liang Yan, Liao-Yuan Yao, Maggie Ng, Wai Kit Tang, Ming-Yi Leung, Vivian Wing-Wah Yam
Summary: Gold(I) sulfido complexes were synthesized and characterized, showing reversible transformation between decanuclear and pentanuclear complexes. The transformation could be monitored by NMR and UV-vis absorption spectroscopy. One complex exhibited stable reversible transformation for over 10 successive cycles in solution. The reversible transformation behavior was found to depend on the bite distance of the ligands.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2022)
Article
Chemistry, Multidisciplinary
Chun-Yin Wong, Shiu-Lun Lai, Ming-Yi Leung, Man-Chung Tang, Lok-Kwan Li, Mei-Yee Chan, Vivian Wing-Wah Yam
Summary: A new series of cyclometalating ligands with bulky substituents are designed and synthesized. These gold(III) complexes exhibit high photoluminescence quantum yields and short excited-state lifetimes in the solid state at room temperature. Organic light-emitting devices (OLEDs) based on these complexes show promising electroluminescence performances with high external quantum efficiencies and efficiency roll-offs. The mercury-free synthesis and record-long operational lifetimes make these complexes potential emitting materials for practical OLEDs.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2023)
Review
Chemistry, Multidisciplinary
Michael Ho-Yeung Chan, Vivian Wing-Wah Yam
Summary: Supramolecular functional materials, stabilized by self-assembled molecules through supramolecular chemistry, have been a promising field. Metal-metal interactions, a type of unconventional noncovalent interaction, have been utilized to construct self-assembled metal-based materials with rich spectroscopic functionalities. However, the systematic control of hierarchical architectures through metal-metal interactions remains challenging.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2022)
Article
Chemistry, Multidisciplinary
Fangrui Zheng, Yuhong Yang, Siye Wu, Shunan Zhao, Yifan Zhu, Huimin Su, Jun-Feng Dai, Zeyin Yan, Lung Wa Chung, Keith Man-Chung Wong
Summary: In contrast to the well-studied dirhodium(II) complexes and iridium(III) complexes, neutral or dicationic dinuclear iridium(II) complexes with unsupported ligands are relatively unexplored. In this study, a series of tetracationic dinuclear iridium(II) complexes with long bond distances and photoluminescent properties were synthesized and characterized. It was found that these complexes exhibit high stability due to London dispersion interactions, despite the long Ir(II)-Ir(II) bond lengths, and show potential for further photoreactivity studies involving the generation of iridium(II) radical monomers.
COMMUNICATIONS CHEMISTRY
(2022)
Article
Chemistry, Multidisciplinary
Youzhi Xu, Fabian Steudel, Ming-Yi Leung, Biao Xia, Max von Delius, Vivian Wing-Wah Yam
Summary: Both pillar[n]arenes (P[n]As) and [n]cycloparaphenylenes ([n]CPPs) have been synthesized and integrated into bismacrocycles [n]CPP-P[5]A. The bismacrocycles exhibit higher photoluminescence quantum yield (phi(F)) compared to the corresponding [n]CPPs. Chiral enantiomers (pR)/(pS)-[8]CPP-P[5]A with circularly polarized luminescence (g(lum)approximate to 0.02) were successfully isolated, and the bismacrocycles showed high affinity and specificity towards pyridinium salts and fullerene derivatives. Transient absorption studies revealed photo-induced electron transfer in [10]CPP-P[5]A superset of C-60 complex. The results suggest the potential applications of [n]CPP-P[5]A in CPL-active materials, multiple guest recognition, and supramolecular polymer preparation.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2023)
Article
Chemistry, Inorganic & Nuclear
Jingyi Lu, Shunan Zhao, Fangfang Wei, Keith Man-Chung Wong
Summary: A series of NIR-emitting rhodium(III) complexes with extended pi-conjugation structure and electron-donating substituents have been synthesized. The luminescence can be further shifted to the red through the introduction of thienyl groups on the benzo[g]quinoxaline moiety. These complexes exhibit luminescence maxima ranging from 763 nm to 792 nm with a quantum yield of 0.41% to 0.66% in dichloromethane solution. This work presents the first examples of NIR-phosphorescent rhodium(III) complexes and offers a new strategy for the development of NIR materials.
EUROPEAN JOURNAL OF INORGANIC CHEMISTRY
(2023)
Article
Chemistry, Multidisciplinary
Vonika Ka-Man Au, Vivian Wing-Wah Yam
Summary: This study designed and synthesized a series of luminescent bis-alkynylgold(III) complexes with bidentate C^N-type ligands and compared their properties with related tridentate cyclometalated complexes. The results showed that all of the complexes exhibit rich photophysical and electrochemical properties, especially strong emissive properties at ambient conditions.
JOURNAL OF THE CHINESE CHEMICAL SOCIETY
(2023)
Article
Chemistry, Organic
Jingjie Cao, Chun-Ting Poon, Michael Ho-Yeung Chan, Eugene Yau-Hin Hong, Yat-Hin Cheng, Franky Ka-Wah Hau, Lixin Wu, Vivian Wing-Wah Yam
Summary: A new class of amphiphilic boron(iii) diketonate compounds has been synthesized, forming thin 2D nanosheet assemblies driven by non-covalent pi-pi interactions and hydrophobic interactions. Detailed studies on the self-assembly mechanism have been conducted using solvent- and temperature-dependent electronic absorption and emission experiments. The supramolecular nanostructures and morphologies have been characterized by TEM, AFM, and XRD, providing insights into the assembly of boron(iii) diketonate coordination materials.
ORGANIC CHEMISTRY FRONTIERS
(2023)
Article
Chemistry, Multidisciplinary
Cathay Chai Au-Yeung, Ming-Yi Leung, Shiu-Lun Lai, Shun-Cheung Cheng, Lok-Kwan Li, Man-Chung Tang, Wing-Kei Kwok, Chi-Chiu Ko, Mei-Yee Chan, Vivian Wing-Wah Yam
Summary: A new class of gold(III) complexes with pyridine-/pyrazine-containing tetradentate ligands has been synthesized and characterized. These complexes exhibit high photoluminescence quantum yields in solid-state thin films and a significant increase in radiative decay rate constant upon increasing temperature. The activation parameters and energy separation values between excited states were determined. Furthermore, strategic modification of the ligand structure can enhance the alignment of the emitting layer and improve the efficiency and performance of organic light-emitting devices.
MATERIALS HORIZONS
(2023)