Splitting a Therapeutic Dose of Thioguanine May Avoid Liver Toxicity and Be an Efficacious Treatment for Severe Inflammatory Bowel Disease

A novel mouse model of veno-occlusive disease provides strategies to prevent thioguanine-induced hepatic toxicity

(2012) Iulia Oancea et al.   GUT

Outcome Following Thiopurine Use in Children With Ulcerative Colitis: A Prospective Multicenter Registry Study

(2011) Jeffrey S Hyams et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Nodular regenerative hyperplasia of the liver: coral atoll-like lesions on ultrasound are characteristic in predisposed patients

(2011) E Caturelli et al.   BRITISH JOURNAL OF RADIOLOGY

Hepatotoxicity associated with 6-methyl mercaptopurine formation during azathioprine and 6-mercaptopurine therapy does not occur on the short-term during 6-thioguanine therapy in IBD treatment

(2011) Dirk P. van Asseldonk et al.   Journal of Crohns & Colitis

Drug-Induced Lupus Anticoagulants and Antiphospholipid Antibodies

(2011) Jeffrey S. Dlott et al.   Current Rheumatology Reports

Oral 6-mercaptopurine versus oral 6-thioguanine and veno-occlusive disease in children with standard-risk acute lymphoblastic leukemia: report of the Children's Oncology Group CCG-1952 clinical trial

(2010) L. C. Stork et al.   BLOOD

Prolonged thioguanine therapy is well tolerated and safe in the treatment of ulcerative colitis

(2010) Dirk P. van Asseldonk et al.   DIGESTIVE AND LIVER DISEASE

A United Kingdom inflammatory bowel disease database: Making the effort worthwhile

(2010) K.D. Bardhan et al.   Journal of Crohns & Colitis

Infliximab, Azathioprine, or Combination Therapy for Crohn's Disease

(2010) Jean Frédéric Colombel et al.   NEW ENGLAND JOURNAL OF MEDICINE

Comparative effectiveness of azathioprine in Crohn’s disease and ulcerative colitis: prospective, long-term, follow-up study of 394 patients

(2008) J. P. GISBERT et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Further experience with the use of 6-thioguanine in patients with Crohnʼs disease

(2008) Azhar Ansari et al.   INFLAMMATORY BOWEL DISEASES

Absence of nodular regenerative hyperplasia after low-dose 6-thioguanine maintenance therapy in inflammatory bowel disease patients

(2007) N.K.H. de Boer et al.   DIGESTIVE AND LIVER DISEASE