Increased Activation of Latent TGF-β1 by αVβ3 in Human Crohnʼs Disease and Fibrosis in TNBS Colitis Can Be Prevented by Cilengitide

Genome-wide association studies and Crohn's disease

(2011) J. C. Lee et al.   Briefings in Functional Genomics

Defective Leukocyte GM-CSF Receptor (CD116) Expression and Function in Inflammatory Bowel Disease

(2011) Jonathan I. Goldstein et al.   GASTROENTEROLOGY

Endogenous IGFBP-3 regulates excess collagen expression in intestinal smooth muscle cells of Crohnʼs disease strictures

(2010) Robert S. Flynn et al.   INFLAMMATORY BOWEL DISEASES

Amelioration of excess collagen IαI, fibrosis, and smooth muscle growth in TNBS-induced colitis in IGF-I(+/−) mice

(2010) Sunila Mahavadi et al.   INFLAMMATORY BOWEL DISEASES

Endogenous IGF-I and αvβ3 integrin ligands regulate increased smooth muscle growth in TNBS-induced colitis

(2009) Krystina B. Hazelgrove et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Smad3 loss confers resistance to the development of trinitrobenzene sulfonic acid-inducedcolorectal fibrosis

(2009) G. Latella et al.   EUROPEAN JOURNAL OF CLINICAL INVESTIGATION

Endogenous IGF-I and αVβ3 Integrin Ligands Regulate Increased Smooth Muscle Hyperplasia in Stricturing Crohn's Disease

(2009) Robert S. Flynn et al.   GASTROENTEROLOGY

Transforming growth factor   signalling and matrix metalloproteinases in the mucosa overlying Crohn's disease strictures

(2009) A Di Sabatino et al.   GUT

Pharmacological inhibition of integrin αvβ3 aggravates experimental liver fibrosis and suppresses hepatic angiogenesis

(2009) Eleonora Patsenker et al.   HEPATOLOGY

Integrins and the activation of latent transforming growth factor β1 – An intimate relationship

(2008) P WIPFF et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

Transcriptomic analysis of intestinal fibrosis-associated gene expression in response to medical therapy in Crohnʼs disease

(2008) John P. Burke et al.   INFLAMMATORY BOWEL DISEASES