Treatment with the Hyaluronic Acid Synthesis Inhibitor 4-Methylumbelliferone Suppresses LPS-Induced Lung Inflammation

Hyaluronan Induces Cell Death in Activated T Cells through CD44

(2014) B. Ruffell et al.   JOURNAL OF IMMUNOLOGY

Consequences of acute ozone exposure imposed on the culminated allergic pulmonary inflammation in an established murine model of asthma

(2013) Xin Zhou   Frontiers in Bioscience-Landmark

Low Molecular Weight Hyaluronan Activates Cytosolic Phospholipase A2α and Eicosanoid Production in Monocytes and Macrophages

(2013) Milena Sokolowska et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Different molecular weight hyaluronic acid effects on human macrophage interleukin 1β production

(2013) Larissa F. Baeva et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Development of a novel treatment for leukemia directed at tumor-associated mRNA splicing

(2013) Dayle A. Daines et al.   LEUKEMIA RESEARCH

Targeting hyaluronic acid production for the treatment of leukemia: Treatment with 4-methylumbelliferone leads to induction of MAPK-mediated apoptosis in K562 leukemia

(2013) Olga N. Uchakina et al.   LEUKEMIA RESEARCH

Treatment with the Hyaluronic Acid Synthesis Inhibitor 4-Methylumbelliferone Suppresses SEB-Induced Lung Inflammation

(2013) Robert McKallip et al.   Toxins

CD44 as a novel target for treatment of staphylococcal enterotoxin B-induced acute inflammatory lung injury

(2012) Jingping Sun et al.   CLINICAL IMMUNOLOGY

The role of hyaluronic acid in SEB-induced acute lung inflammation

(2012) Olga N. Uchakina et al.   CLINICAL IMMUNOLOGY

Corticosteroid administration reduces the concentration of hyaluronan in bronchoalveolar lavage in a murine model of eosinophilic airway inflammation

(2012) Glenda Ernst et al.   INFLAMMATION RESEARCH

Pharmacotherapy for Acute Respiratory Distress Syndrome

(2012) Hira Shafeeq et al.   PHARMACOTHERAPY

Contact Sensitizers Induce Skin Inflammation via ROS Production and Hyaluronic Acid Degradation

(2012) Philipp R. Esser et al.   PLoS One

Inhibition of hyaluronan retention by 4-methylumbelliferone suppresses osteosarcoma cells in vitro and lung metastasis in vivo

(2011) E Arai et al.   BRITISH JOURNAL OF CANCER

Antitumor effects of hyaluronic acid inhibitor 4-methylumbelliferone in an orthotopic hepatocellular carcinoma model in mice

(2011) F. Piccioni et al.   GLYCOBIOLOGY

Inhibition of hyaluronan synthesis in breast cancer cells by 4-methylumbelliferone suppresses tumorigenicity in vitro and metastatic lesions of bone in vivo

(2011) Hiroshi Urakawa et al.   INTERNATIONAL JOURNAL OF CANCER

Role of hyaluronan and hyaluronan-binding proteins in human asthma

(2011) Jiurong Liang et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Hyaluronan as an Immune Regulator in Human Diseases

(2011) Dianhua Jiang et al.   PHYSIOLOGICAL REVIEWS

Quercetin Inhibits IL-1β-Induced Inflammation, Hyaluronan Production and Adipogenesis in Orbital Fibroblasts from Graves' Orbitopathy

(2011) Jin Sook Yoon et al.   PLoS One

ECM components guide IL-10 producing regulatory T-cell (TR1) induction from effector memory T-cell precursors

(2011) P. L. Bollyky et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

High-molecular-weight hyaluronan is a novel inhibitor of pulmonary vascular leakiness

(2010) Patrick A. Singleton et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Small hyaluronan oligosaccharides induce inflammation by engaging both toll-like-4 and CD44 receptors in human chondrocytes

(2010) Giuseppe M. Campo et al.   BIOCHEMICAL PHARMACOLOGY

4-Methylumbelliferone inhibits tumour cell growth and the activation of stromal hyaluronan synthesis by melanoma cell-derived factors

(2010) M. Edward et al.   BRITISH JOURNAL OF DERMATOLOGY

Antitumor Activity of Hyaluronic Acid Synthesis Inhibitor 4-Methylumbelliferone in Prostate Cancer Cells

(2010) Vinata B. Lokeshwar et al.   CANCER RESEARCH

Oral Administration of High Molecular Weight Hyaluronan (900 kDa) Controls Immune System via Toll-like Receptor 4 in the Intestinal Epithelium

(2010) Akira Asari et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

4-Methylumbelliferone inhibits hyaluronan synthesis by depletion of cellular UDP-glucuronic acid and downregulation of hyaluronan synthase 2 and 3

(2009) Anne Kultti et al.   EXPERIMENTAL CELL RESEARCH

Differential effect of molecular mass hyaluronan on lipopolysaccharide-induced damage in chondrocytes

(2009) Giuseppe M. Campo et al.   Innate Immunity

Animal models of sepsis and sepsis-induced kidney injury

(2009) Kent Doi et al.   JOURNAL OF CLINICAL INVESTIGATION

Intact extracellular matrix and the maintenance of immune tolerance: high molecular weight hyaluronan promotes persistence of induced CD4+CD25+ regulatory T cells

(2009) Paul L. Bollyky et al.   JOURNAL OF LEUKOCYTE BIOLOGY