Article
Immunology
Emilio Jimenez-Martinez, Guillermo Cuervo, Jordi Carratala, Ana Hornero, Pilar Ciercoles, Andres Gabarros, Carmen Cabellos, Ivan Pelegrin, Maria Angeles Dominguez Luzon, Dolores Garcia-Somoza, Jordi Camara, Cristian Tebe, Jordi Adamuz, Miquel Pujol
Summary: The study found that implementing a care bundle in patients undergoing craniotomy can effectively prevent surgical site infections, especially infections after craniotomy. This comprehensive preventive strategy significantly reduces the incidence of infections and should be considered for implementation in centers with high infection risk.
CLINICAL INFECTIOUS DISEASES
(2021)
Article
Oncology
Nana Sugamata, Takashi Okuyama, Emiko Takeshita, Haruka Oi, Yuhei Hakozaki, Shunya Miyazaki, Musashi Takada, Takashi Mitsui, Takuji Noro, Hideyuki Yoshitomi, Masatoshi Oya
Summary: This study found that infectious complications, particularly surgical site infection (SSI), have an impact on long-term oncological results after laparoscopic resection of colorectal cancer. Patients with SSI had a significantly lower postoperative relapse-free survival rate compared to those without SSI, and the differences in survival were significant after both colectomy and rectal resection. The occurrence of SSI was identified as an independent co-factor for relapse-free survival.
WORLD JOURNAL OF SURGICAL ONCOLOGY
(2022)
Review
Medicine, General & Internal
Jessica L. Seidelman, Christopher R. Mantyh, Deverick J. Anderson
Summary: Surgical site infections occur in 0.5% to 3% of patients undergoing surgery and are associated with longer hospital stays. Measures such as avoiding razors, maintaining normothermia, using chlorhexidine gluconate plus alcohol-based skin preparation, decolonization with intranasal antistaphylococcal agents, controlling perioperative glucose concentrations, and using negative pressure wound therapy can reduce the rate of surgical site infections.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
(2023)
Article
Infectious Diseases
Jerome Ory, Quang Le Minh, Hung Phan Tien, Vinh Vu Hai, Elodie Careno, Tatiana Price, Alexandre Andrieux, Julien Crouzet, Catherine Dunyach-Remy, Didier Laureillard, Jean-Philippe Lavigne, Albert Sotto
Summary: This study examined the changes in surgical site infection rates before and after the implementation of antibiotic stewardship programs and infection control measures in a Vietnamese tertiary care hospital. The results showed a decrease in surgical site infection rates after the implementation of these programs, although the difference was not statistically significant. Comprehensive infection control education and policies are needed in Vietnamese hospitals to prevent surgical site infections.
Review
Nursing
Camila Dalcol, Judith Tanner, Vanessa de Brito Poveda
Summary: This scoping review examines the development and use of digital tools for post-discharge surgical site infection surveillance. A total of 10 digital tools were identified, including one intellectual property record and 13 scientific articles. The main functionalities of the digital tools include structured questionnaires, attachment of wound images, integrated web systems, and evaluation of data by professionals. The findings suggest that digital tools have the potential to improve surgical site infection surveillance and remote monitoring using mobile technology can reduce unnecessary patient visits and increase patient satisfaction.
JOURNAL OF ADVANCED NURSING
(2023)
Review
Medicine, General & Internal
Stuart Hastings, Paul S. Myles, Robert L. Medcalf
Summary: Surgical site infections (SSIs) are a common economic burden that increase patient morbidity and mortality. Although antibiotic prophylaxis is the primary prevention intervention, it may be less effective due to emerging antibiotic resistant organisms. Exploration of novel therapies, such as tranexamic acid, as adjunct to antibiotics is warranted to reduce SSIs.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Dermatology
Xiao-Yan Wang, Xiu-Qin Wang, Zhong-Hua Tian, Wei Li, Ning He, Gui-Qin Zhang
Summary: This meta-analysis found that the application of humanised care during the perioperative period of caesarean section can reduce the incidence of postoperative wound infections and complications, as well as alleviate maternal anxiety and depression. Therefore, the findings of this study are worthy of clinical promotion and application.
INTERNATIONAL WOUND JOURNAL
(2023)
Review
Dermatology
Pinar Avsar, Declan Patton, Aicha Sayeh, Karen Ousey, Joanna Blackburn, Tom O'Connor, Zena Moore
Summary: This systematic review examines the effects of care bundles on the incidence of surgical site infections (SSIs). The findings indicate that implementing care bundles significantly reduces the odds of SSI development. However, more research with standardized care bundles is needed to confirm these results.
ADVANCES IN SKIN & WOUND CARE
(2022)
Review
Medicine, General & Internal
Trisha N. Peel, Eliza Watson, Sue J. Lee
Summary: The use of chlorhexidine-alcohol for surgical site skin preparation was found to be more effective in reducing the risk of surgical site infections compared to iodophor-alcohol. However, the efficacy of chlorhexidine-alcohol may vary depending on the type of surgical procedure.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Public, Environmental & Occupational Health
T. Zhang, X. Lian, Y. Chen, B. Cai, J. Xu
Summary: This study analyzed the incidence and characteristics of postoperative surgical site infection (SSI) after posterior thor-acolumbar and lumbar instrumentation. The results showed an average SSI rate of 1.8%. Most patients with deep wound SSI can be successfully treated with retention of implants, but early diagnosis, positive revision surgery, strict irrigation, thorough debridement, and long-term antibiotic treatment are crucial.
JOURNAL OF HOSPITAL INFECTION
(2022)
Review
Public, Environmental & Occupational Health
Emmanuel Piednoir, Joan Robert-Yap, Patrice Baillet, Emilie Lermite, Niki Christou
Summary: Surgical site infections pose a significant economic burden, with costs varying depending on factors such as the patient and the type of surgery. Prevention of infections is a profitable concept for surgery and should be integrated into healthcare management globally.
FRONTIERS IN PUBLIC HEALTH
(2021)
Article
Infectious Diseases
Mathilde Berghmans, Leopold de Ghellinck, Julien De Greef, Melissa Di Santo, Jose-Geraldo Ribeiro Vaz, Francis Zech, Leila Belkhir
Summary: The management of surgical site infection after craniotomy remains challenging. This study found that bone flap removal and parenteral antibiotic agents are important in the management and are associated with decreased risk of relapse.
SURGICAL INFECTIONS
(2022)
Article
Veterinary Sciences
Ana C. Castejon-Gonzalez, Darko Stefanovski, Alexander M. Reiter
Summary: Acquired midline palate defects are common in cats and can be caused by trauma. This retrospective study analyzes the characteristics, causes, treatments, and outcomes of PDE in 25 cats. The results show that early surgical treatment within 5 days is highly successful in repairing these defects.
FRONTIERS IN VETERINARY SCIENCE
(2022)
Article
Dermatology
Kylie Sandy-Hodgetts, Charles A. Andersen, Omar Al-Jalodi, Laura Serena, Christina Teimouri, Thomas E. Serena
Summary: The detection of bacterial burden near surgical wounds is crucial for reducing surgical site infections. Fluorescence imaging shows potential to improve detection sensitivity compared to clinical signs and symptoms. Advanced imaging techniques can help monitor bacterial burden and reduce the incidence of SSIs.
INTERNATIONAL WOUND JOURNAL
(2022)
Article
Oncology
Takumi Hasegawa, Daisuke Takeda, Motofumi Tanaka, Rika Amano, Izumi Saito, Yasumasa Kakei, Akira Kimoto, Takumi Fukumoto, Masaya Akashi
Summary: This study retrospectively investigated the relationship between risk factors and post-hepatectomy surgical site infection (SSI) and other complications in HCC patients. The results showed that bacterial infection of ascites, lack of preoperative oral management intervention, and severe liver fibrosis were associated with SSI, while severe liver fibrosis, hypoalbuminemia, blood transfusion, and longer operation time were associated with postoperative complications. Preoperative oral management intervention may reduce the risk of SSI in patients undergoing hepatectomy for HCC.
SUPPORTIVE CARE IN CANCER
(2021)
Article
Public, Environmental & Occupational Health
Lona Mody, Ibukunoluwa C. Akinboyo, Hilary M. Babcock, Werner E. Bischoff, Vincent Chi-Chung Cheng, Kathleen Chiotos, Kimberly C. Claeys, K. C. Coffey, Daniel J. Diekema, Curtis J. Donskey, Katherine D. Ellingson, Heather M. Gilmartin, Shruti K. Gohil, Anthony D. Harris, Sara C. Keller, Eili Y. Klein, Sarah L. Krein, Jennie H. Kwon, Adam S. Lauring, Daniel J. Livorsi, Eric T. Lofgren, Katreena Merrill, Aaron M. Milstone, Elizabeth A. Monsees, Daniel J. Morgan, Luci P. Perri, Christopher D. Pfeiffer, Clare Rock, Sanjay Saint, Emily Sickbert-Bennett, Felicia Skelton, Katie J. Suda, Thomas R. Talbot, Valerie M. Vaughn, David J. Weber, Timothy L. Wiemken, Mohamed H. Yassin, Matthew J. Ziegler, Deverick J. Anderson
Summary: This white paper identifies knowledge gaps and challenges in healthcare epidemiology research related to COVID-19 and proposes a research agenda. It emphasizes the need for collaboration across disciplines and addresses issues related to nursing homes and social disparities.
INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY
(2022)
Article
Public, Environmental & Occupational Health
Ibukunoluwa C. Akinboyo, Rebecca R. Young, Michael J. Smith, Sarah S. Lewis, Becky A. Smith, Deverick J. Anderson
Summary: Through prospective surveillance in community hospitals, 84 pediatric healthcare-associated infections were identified over a 6-year period. 61% of these infections were pediatric central-line-associated bloodstream infections, and they often occurred in children under 1 year of age.
INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY
(2022)
Editorial Material
Infectious Diseases
Sonali D. Advani, Deverick J. Anderson
LANCET INFECTIOUS DISEASES
(2021)
Article
Medicine, General & Internal
Eric T. Lofgren, Matthew Mietchen, Kristen V. Dicks, Rebekah Moehring, Deverick Anderson
Summary: The study suggests that there is significant room for improvement in anti-MRSA disinfectants, including both the compounds themselves and their delivery mechanisms. Despite the decolonization estimates found in this study, these agents have robust outcomes even after delays in administration, which may help alleviate concerns over patient comfort and toxic effects.
Article
Medicine, General & Internal
Christina D. Mack, John DiFiori, Caroline G. Tai, Kristin Y. Shiue, Yonatan H. Grad, Deverick J. Anderson, David D. Ho, Leroy Sims, Christopher LeMay, Jimmie Mancell, Lisa L. Maragakis
Summary: In this retrospective cohort study of the 2020 NBA closed campus occupational health program, recovered individuals who continued to test positive for SARS-CoV-2 following discontinuation of isolation were not infectious to others. These findings support time-based US Centers of Disease Control and Prevention recommendations for ending isolation.
JAMA INTERNAL MEDICINE
(2021)
Article
Public, Environmental & Occupational Health
Robert Rolfe, Charles Kwobah, Florida Muro, Anushka Ruwanpathirana, Furaha Lyamuya, Champica Bodinayake, Ajith Nagahawatte, Bhagya Piyasiri, Tianchen Sheng, John Bollinger, Chi Zhang, Truls Ostbye, Shamim Ali, Richard Drew, Peter Kussin, Deverick J. Anderson, Christopher W. Woods, Melissa H. Watt, Blandina T. Mmbaga, L. Gayani Tillekeratne
Summary: This study identified important barriers to implementing ASPs in three tertiary care centers in LMICs, including improving drug availability, enhancing availability of and trust in microbiologic data, developing local guidelines, and providing education to physicians regarding antimicrobial prescribing.
ANTIMICROBIAL RESISTANCE AND INFECTION CONTROL
(2021)
Article
Public, Environmental & Occupational Health
Tamara Pilishvili, Katherine E. Fleming-Dutra, Jennifer L. Farrar, Ryan Gierke, Nicholas M. Mohr, David A. Talan, Anusha Krishnadasan, Karisa K. Harland, Howard A. Smithline, Peter C. Hou, Lilly C. Lee, Stephen C. Lim, Gregory J. Moran, Elizabeth Krebs, Mark Steele, David G. Beiser, Brett Faine, John P. Haran, Utsav Nandi, Walter A. Schrading, Brian Chinnock, Daniel J. Henning, Frank LoVecchio, Joelle Nadle, Devra Barter, Monica Brackney, Amber Britton, Kaytlynn Marceaux-Galli, Sarah Lim, Erin C. Phipps, Ghinwa Dumyati, Rebecca Pierce, Tiffanie M. Markus, Deverick J. Anderson, Amanda K. Debes, Michael Lin, Jeanmarie Mayer, Hilary M. Babcock, Nasia Safdar, Marc Fischer, Rosalyn Singleton, Nora Chea, Shelley S. Magill, Jennifer Verani, Stephanie Schrag
MMWR-MORBIDITY AND MORTALITY WEEKLY REPORT
(2021)
Article
Medicine, General & Internal
Nicholas A. Turner, Rebekah Wrenn, Christina Sarubbi, Renee Kleris, Patricia L. Lugar, Christine Radojicic, Rebekah W. Moehring, Deverick J. Anderson
Summary: A pharmacist-led allergy assessment program was associated with decreased use of nonpenicillin alternative antibiotics and high-CDI-risk antibiotics at the hospital level. Individual patients who underwent comprehensive allergy assessment were less likely to receive high-CDI-risk antibiotics at discharge, indicating potential benefits of allergy delabeling. However, reductions in mortality and hospital-acquired CDI risk did not reach statistical significance, suggesting longer-term benefits may require further study.
Article
Medicine, General & Internal
Rebekah W. Moehring, Matthew Phelan, Eric Lofgren, Alicia Nelson, Elizabeth Dodds Ashley, Deverick J. Anderson, Benjamin A. Goldstein
Summary: This study found that variables derived from electronic health records accurately identified inpatient antimicrobial use, suggesting that future risk-adjustment strategies incorporating encounter-level information may improve comparisons for hospital antimicrobial stewardship assessments.
Article
Public, Environmental & Occupational Health
Sonali D. Advani, Becky A. Smith, Jessica Seidelman, Nicholas Turner, Deverick J. Anderson, Sarah S. Lewis
Summary: The paradoxical relationship between standardized infection ratio and standardized utilization ratio for CAUTIs compared to CLABSIs, along with challenges in CAUTI definition, incentivizes hospitals to prioritize prevention efforts on urine culture stewardship.
INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY
(2022)
Article
Public, Environmental & Occupational Health
Jessica L. Seidelman, Rebekah W. Moehring, David J. Weber, Deverick J. Anderson, Sarah S. Lewis
Summary: Patients who reported a penicillin or cephalosporin allergy had a higher risk of developing a surgical site infection (SSI) compared to non-allergic patients. However, the choice of surgical prophylaxis did not significantly affect this association. The reported allergy may serve as a surrogate marker for a more complex patient population.
INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY
(2022)
Article
Public, Environmental & Occupational Health
Sarah S. Lewis, Ibukunoluwa C. Kalu, Jessica Seidelman, Deverick J. Anderson, Rebekah W. Moehring, Becky A. Smith
Summary: The study found that without real-time adjudication, nearly 50% of HA-COVID-19 cases identified using electronic definitions were misclassified. Both electronic and traditional contact tracing methods likely underestimated the incidence of HA-COVID-19.
INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY
(2022)
Article
Public, Environmental & Occupational Health
Diego Schaps, Andrew W. Godfrey, Deverick J. Anderson
Summary: This study found that patients who were transported to the emergency department by ambulance had a higher risk of developing MRSA or VRE within 30 days compared to those who arrived by private vehicle.
INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY
(2022)
Article
Biochemistry & Molecular Biology
Stephen M. Kissler, Joseph R. Fauver, Christina Mack, Scott W. Olesen, Caroline Tai, Kristin Y. Shiue, Chaney C. Kalinich, Sarah Jednak, Isabel M. Ott, Chantal B. F. Vogels, Jay Wohlgemuth, James Weisberger, John DiFiori, Deverick J. Anderson, Jimmie Mancell, David D. Ho, Nathan D. Grubaugh, Yonatan H. Grad
Summary: The study analyzed the viral RNA trajectories for 68 individuals during the resumption of the NBA season, finding that viral RNA concentrations typically peak 3.3 days after the onset of infection, with differences in the duration of the clearance phase between symptomatic and asymptomatic individuals. A second test within 2 days after an initial positive PCR test improves certainty about the infection stage, and the sensitivity of tests decreases with longer turnaround times.
Article
Public, Environmental & Occupational Health
Christina D. Mack, Erin B. Wasserman, Cria G. Perrine, Adam MacNeil, Deverick J. Anderson, Emily Myers, Sabrina Smith, L. Clifford McDonald, Michael Osterholm, Gary S. Solomon, Thom Mayer, Allen Sills
MMWR-MORBIDITY AND MORTALITY WEEKLY REPORT
(2021)
