Article
Public, Environmental & Occupational Health
Deborah S. Yokoe, Sonali D. Advani, Deverick J. Anderson, Hilary M. Babcock, Michael Bell, Sean M. Berenholtz, Kristina A. Bryant, Niccolo Buetti, Michael S. Calderwood, David P. Calfee, Valerie M. Deloney, Erik R. Dubberke, Katherine D. Ellingson, Neil O. Fishman, Dale N. Gerding, Janet Glowicz, Mary K. Hayden, Keith S. Kaye, Larry K. Kociolek, Emily Landon, Elaine L. Larson, Anurag N. Malani, Jonas Marschall, Jennifer Meddings, Leonard A. Mermel, Payal K. Patel, Trish M. Perl, Kyle J. Popovich, Joshua K. Schaffzin, Edward Septimus, Kavita K. Trivedi, Robert A. Weinstein, Lisa L. Maragakis
Summary: Since the initial publication in 2008, preventing healthcare-associated infections (HAIs) has remained a national priority. Despite progress in research, HAIs continue to have a significant impact, and the COVID-19 pandemic has highlighted the importance of infection prevention. The Compendium: 2022 Updates provides up-to-date guidance for acute care hospitals to prioritize and implement HAI prevention efforts.
INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY
(2023)
Letter
Public, Environmental & Occupational Health
Katrina Browne, Brett G. Mitchell
Summary: Infection transmission in healthcare is a complex issue that involves the interplay between pathogens, hosts, and the environment. Environmental cleaning is one strategy to prevent transmission, and a multimodal intervention is key to reducing the risk of healthcare-associated infections through the environment.
ANTIMICROBIAL RESISTANCE AND INFECTION CONTROL
(2023)
Article
Public, Environmental & Occupational Health
Michael S. Calderwood, Deverick J. Anderson, Dale W. Bratzler, E. Patchen Dellinger, Sylvia Garcia-Houchins, Lisa L. Maragakis, Ann-Christine Nyquist, Kiran M. Perkins, Michael Anne Preas, Lisa Saiman, Joshua K. Schaffzin, Marin Schweizer, Deborah S. Yokoe, Keith S. Kaye
Summary: The purpose of this document is to provide practical recommendations for acute-care hospitals to implement and prioritize their efforts in preventing surgical-site infections. It is an updated version of the Strategies to Prevent Surgical Site Infections in Acute Care Hospitals published in 2014. This expert guidance document is sponsored by the Society for Healthcare Epidemiology of America (SHEA) and represents a collaborative effort involving various organizations and societies with content expertise.
INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY
(2023)
Article
Public, Environmental & Occupational Health
Curtis J. Donskey
Summary: In recent years, there has been increasing interest in empowering patients to participate in the prevention of healthcare-associated infections. However, patients often lack awareness of the risk of acquiring and spreading healthcare-associated pathogens, and have limited information on how they can contribute to infection prevention efforts. This review highlights areas where patient empowerment initiatives in infection control and antimicrobial stewardship can be beneficial, and provides evidence for their effectiveness.
AMERICAN JOURNAL OF INFECTION CONTROL
(2023)
Review
Infectious Diseases
Edward J. Septimus
Summary: The purpose of this review is to highlight important changes since the 2014 Compendium and to provide an overview of the surveillance and reporting requirements for healthcare-associated infections (HAIs) in US hospitals, as well as recent findings and challenges posed by the COVID-19 pandemic.
CURRENT OPINION IN INFECTIOUS DISEASES
(2023)
Article
Public, Environmental & Occupational Health
Payal K. Patel, Sonali D. Advani, Aaron D. Kofman, Evelyn Lo, Lisa L. Maragakis, David A. Pegues, Ann Marie Pettis, Sanjay Saint, Barbara Trautner, Deborah S. Yokoe, Jennifer Meddings
Summary: The purpose of this document is to provide concise and practical recommendations for healthcare professionals in acute-care hospitals to prevent catheter-associated urinary tract infections (CAUTIs). It is an updated version of the 2014 publication "Strategies to Prevent Catheter-Associated Urinary Tract Infections in Acute-Care Hospitals" and was collaboratively developed by SHEA, IDSA, APIC, AHA, and The Joint Commission.
INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY
(2023)
Article
Public, Environmental & Occupational Health
Janet B. Glowicz, Emily Landon, Emily E. Sickbert-Bennett, Allison E. Aiello, Karen deKay, Karen K. Hoffmann, Lisa Maragakis, Russell N. Olmsted, Philip M. Polgreen, Polly A. Trexler, Margaret A. VanAmringe, Amber R. Wood, Deborah Yokoe, Katherine D. Ellingson
Summary: The purpose of this document is to provide practical recommendations to acute-care hospitals for preventing healthcare-associated infections through hand hygiene. It updates the previous version published in 2014 and is sponsored by the Society for Healthcare Epidemiology (SHEA) in collaboration with other organizations. This expert guidance document has major contributions from representatives of various organizations and societies.
INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY
(2023)
Review
Immunology
Ayman Elbehiry, Eman Marzouk, Adil Abalkhail, Yasmine El-Garawany, Sulaiman Anagreyyah, Yaser Alnafea, Abdulaziz M. Almuzaini, Waleed Alwarhi, Mohammed Rawway, Abdelmaged Draz
Summary: The growing risk of antimicrobial resistance (AMR) has negative impacts on the healthcare system, calling for the development of quick diagnostic tools and new treatment approaches to combat multidrug-resistant pathogens in healthcare-associated infections (HAIs).
Article
Public, Environmental & Occupational Health
Kavita K. Trivedi, Joshua K. Schaffzin, Valerie M. Deloney, Kathy Aureden, Ruth Carrico, Sylvia Garcia-Houchins, J. Hudson Garrett Jr, Janet Glowicz, Grace M. Lee, Lisa L. Maragakis, Julia Moody, Ann Marie Pettis, Sanjay Saint, Marin L. Schweizer, Deborah S. Yokoe, Sean Berenholtz
Summary: This article introduces and explains common implementation concepts and frameworks in healthcare epidemiology and infection prevention and control. It can be used as a standalone guide or paired with the SHEA/IDSA/APIC Compendium of Strategies to Prevent Healthcare-Associated Infections in Acute Care Hospitals: 2022 Updates. The article focuses on broad behavioral and socio-adaptive concepts and provides strategies for implementation using various conceptual models and frameworks.
INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY
(2023)
Review
Microbiology
Mohd W. Azam, Raffaele Zarrilli, Asad U. Khan
Summary: The Enterobacterales order is a large group of Gram-negative bacteria that includes both pathogenic and nonpathogenic members, including beneficial gut microbiota. Pathogenic members produce virulence factors and display antimicrobial resistance. This review focuses on the virulence factors, pathogenicity, and infections caused by multidrug-resistant Enterobacterales, particularly E. coli and similar bacterial species. The review also discusses different approaches for combating these infections. Understanding the virulence factors of pathogenic bacteria can aid in the development of novel strategies to treat infections caused by them.
Article
Medicine, General & Internal
Metsini Aliki, Widmer Andreas, Zingg Walter, Gardiol Celine, Vuichard-Gysin Danielle, Eder Marcus, Maag Judith, Schlegel Matthias, Marschall Jonas, Harbarth Stephan, Sommerstein Rami
Summary: The majority of Swiss acute care hospitals have established surveillance systems for HAI, but challenges remain in terms of EMR systems and personnel resources. Nearly one-quarter of hospitals expressed willingness to participate in the pilot phase of a new surveillance system.
SWISS MEDICAL WEEKLY
(2021)
Article
Public, Environmental & Occupational Health
Janneke D. M. Verberk, Tjallie I. I. van der Kooi, Nynke A. Kampstra, Naomi Reimes, Stephanie M. van Rooden, Titia E. M. Hopmans, Suzanne E. Geerlings, Sabine C. de Greeff
Summary: During the COVID-19 pandemic, the number of healthcare-associated infections (HAIs) increased in Dutch hospitals, particularly for ventilator-associated pneumonia (VAP), gastro-intestinal infections (GIs), and central nervous system (CNS) infections. However, no significant changes were observed in surgical site infections (SSIs), except for a decrease after colorectal surgeries. The incidence of catheter-related bloodstream infections (CRBSIs) was also significantly higher during the pandemic, especially in both COVID-19 and non-COVID-19 patients in the intensive care unit (ICU).
ANTIMICROBIAL RESISTANCE AND INFECTION CONTROL
(2023)
Article
Infectious Diseases
Nicolas Francisco Fernandez-Martinez, Mario Rivera-Izquierdo, Rocio Ortiz-Gonzalez-Serna, Virginia Martinez-Ruiz, Pablo Lardelli-Claret, Adrian Hugo Aginagalde-Llorente, Maria del Carmen Valero-Ubierna, Maria Auxiliadora Vergara-Diaz, Nicola Lorusso
Summary: This study indicates that social factors should be considered when investigating healthcare-associated infections caused by multidrug-resistant bacteria. The heterogeneity in the incidence of cases between municipalities in Andalusia may be explained by social determinants of health, as well as under-notification.
Article
Health Care Sciences & Services
Saleh A. Alrebish, Hasan S. Yusufoglu, Reem F. Alotibi, Nawal S. Abdulkhalik, Nehad J. Ahmed, Amer H. Khan
Summary: Healthcare-associated infections, such as ventilator-associated pneumonia, central line-associated bloodstream infections, and catheter-associated urinary tract infections, were investigated in a retrospective study at a public hospital in Unaizah, Saudi Arabia in 2021. The rates of surgical site infections, catheter-associated urinary tract infections, central line-associated bloodstream infections, ventilator-associated pneumonia, and infections caused by multidrug-resistant organisms were reported. The compliance rates for various infection prevention techniques were also assessed, emphasizing the importance of hand hygiene and personal safety equipment.
Article
Medicine, General & Internal
Anne F. Luetkemeyer, Deborah Donnell, Julia C. Dombrowski, Stephanie Cohen, Cole Grabow, Clare E. Brown, Cheryl Malinski, Rodney Perkins, Melody Nasser, Carolina Lopez, Eric Vittinghoff, Susan P. Buchbinder, Hyman Scott, Edwin D. Charlebois, Diane V. Havlir, Olusegun O. Soge, Connie Celum
Summary: In this study, it was found that doxycycline postexposure prophylaxis significantly reduced the incidence of sexually transmitted infections (STIs) among MSM and transgender women. The use of doxycycline was shown to be effective in preventing STIs in this population.
NEW ENGLAND JOURNAL OF MEDICINE
(2023)
Article
Public, Environmental & Occupational Health
Lona Mody, Ibukunoluwa C. Akinboyo, Hilary M. Babcock, Werner E. Bischoff, Vincent Chi-Chung Cheng, Kathleen Chiotos, Kimberly C. Claeys, K. C. Coffey, Daniel J. Diekema, Curtis J. Donskey, Katherine D. Ellingson, Heather M. Gilmartin, Shruti K. Gohil, Anthony D. Harris, Sara C. Keller, Eili Y. Klein, Sarah L. Krein, Jennie H. Kwon, Adam S. Lauring, Daniel J. Livorsi, Eric T. Lofgren, Katreena Merrill, Aaron M. Milstone, Elizabeth A. Monsees, Daniel J. Morgan, Luci P. Perri, Christopher D. Pfeiffer, Clare Rock, Sanjay Saint, Emily Sickbert-Bennett, Felicia Skelton, Katie J. Suda, Thomas R. Talbot, Valerie M. Vaughn, David J. Weber, Timothy L. Wiemken, Mohamed H. Yassin, Matthew J. Ziegler, Deverick J. Anderson
Summary: This white paper identifies knowledge gaps and challenges in healthcare epidemiology research related to COVID-19 and proposes a research agenda. It emphasizes the need for collaboration across disciplines and addresses issues related to nursing homes and social disparities.
INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY
(2022)
Article
Public, Environmental & Occupational Health
Ibukunoluwa C. Akinboyo, Rebecca R. Young, Michael J. Smith, Sarah S. Lewis, Becky A. Smith, Deverick J. Anderson
Summary: Through prospective surveillance in community hospitals, 84 pediatric healthcare-associated infections were identified over a 6-year period. 61% of these infections were pediatric central-line-associated bloodstream infections, and they often occurred in children under 1 year of age.
INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY
(2022)
Letter
Public, Environmental & Occupational Health
Bernard Surial, Miriam Vazquez, Walter Steiger, Eveline Rolli, Simon Brand, Konrad Muhlethaler, Jonas Marschall
INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY
(2022)
Article
Public, Environmental & Occupational Health
Katherine D. Ellingson, Brie N. Noble, Genevieve L. Buser, Graham M. Snyder, Jessina C. McGregor, Clare Rock, Teena Chopra, Lona Mody, Jon P. Furuno
Summary: Most hospitals have interfacility transfer communication (IFTC) protocols in place, which are associated with reduced communication barriers. However, most respondents reported a lack of standardization in communication protocols.
INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY
(2022)
Article
Public, Environmental & Occupational Health
Sonali D. Advani, Becky A. Smith, Jessica Seidelman, Nicholas Turner, Deverick J. Anderson, Sarah S. Lewis
Summary: The paradoxical relationship between standardized infection ratio and standardized utilization ratio for CAUTIs compared to CLABSIs, along with challenges in CAUTI definition, incentivizes hospitals to prioritize prevention efforts on urine culture stewardship.
INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY
(2022)
Article
Public, Environmental & Occupational Health
Jessica L. Seidelman, Rebekah W. Moehring, David J. Weber, Deverick J. Anderson, Sarah S. Lewis
Summary: Patients who reported a penicillin or cephalosporin allergy had a higher risk of developing a surgical site infection (SSI) compared to non-allergic patients. However, the choice of surgical prophylaxis did not significantly affect this association. The reported allergy may serve as a surrogate marker for a more complex patient population.
INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY
(2022)
Article
Public, Environmental & Occupational Health
Michele Birrer, Martin Perrig, Fabienne Hobi, Christina Gfeller, Andrew Atkinson, Martin Egger, Corinne Bartholdi, Drahomir Aujesky, Jonas Marschall, Rami Sommerstein
Summary: Droplet precautions on-site (DroPS) may be a simple and potentially resource-saving alternative to the standard single room isolation strategy for respiratory viral infections.
ANTIMICROBIAL RESISTANCE AND INFECTION CONTROL
(2022)
Article
Public, Environmental & Occupational Health
Niccolo Buetti, Jonas Marschall, Marci Drees, Mohamad G. Fakih, Lynn Hadaway, Lisa L. Maragakis, Elizabeth Monsees, Shannon Novosad, Naomi P. O'Grady, Mark E. Rupp, Joshua Wolf, Deborah Yokoe, Leonard A. Mermel
INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY
(2022)
Review
Immunology
Philipp Jent, Julia Berger, Annette Kuhn, Barbara W. Trautner, Andrew Atkinson, Jonas Marschall
Summary: Recurrent urinary tract infections are common, and antibiotic prophylaxis significantly reduces the risk of developing UTIs. Different antibiotics appear to have similar efficacy, and intermittent application is equally effective as continuous application.
OPEN FORUM INFECTIOUS DISEASES
(2022)
Article
Public, Environmental & Occupational Health
Andrew Atkinson, Benjamin Ellenberger, Vanja Piezzi, Tanja Kaspar, Luisa Salazar-Vizcaya, Olga Endrich, Alexander B. Leichtle, Jonas Marschall
Summary: This study investigated a nosocomial outbreak of vancomycin-resistant enterococci (VRE) by applying machine-learning and graph-theoretical methods. The findings identified risk factors for VRE colonization and revealed three main pathways for VRE transmission: healthcare personnel, medical devices, and patient rooms.
INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY
(2023)
Article
Psychology, Clinical
Alexa B. Chandler, Aubrey A. Wank, John R. Vanuk, Mary-Frances O'connor, Bradley A. Dreifuss, Heather M. Dreifuss, Katherine D. Ellingson, Sana M. Khan, Sydney E. Friedman, Amy Athey
Summary: Keeping healthcare workers resilient during the COVID-19 pandemic is crucial to ensure high-quality care and adherence to infection prevention protocols. By implementing an online psychological first aid program, we addressed the psychological support needs of healthcare workers, including obtaining clear information, navigating new responsibilities, and managing overwhelming emotions.
JOURNAL OF CLINICAL PSYCHOLOGY IN MEDICAL SETTINGS
(2023)
Article
Infectious Diseases
Brooke A. Hawkes, Sana M. Khan, Melanie L. Bell, Jill Guernsey de Zapien, Kacey C. Ernst, Katherine D. Ellingson
Summary: This study investigates the association between non-prescription antibiotic use and healthcare system distrust in the United States and Mexico. The findings suggest that individuals with higher levels of healthcare system distrust are less likely to use non-prescription antibiotics, highlighting the importance of community-based antibiotic stewardship.
Article
Medicine, General & Internal
Yvonne Pfeiffer, Andrew Atkinson, Judith Maag, Michael A. Lane, David Schwappach, Jonas Marschall
Summary: This study aimed to investigate the relationship between surgical site infections (SSIs) and safety and teamwork climate. The findings suggest a possible negative correlation between climate level and SSI rate, while no associations were found for climate strength.
Article
Immunology
Mladen Jergovic, Christopher P. Coplen, Jennifer L. Uhrlaub, Shawn C. Beitel, Jefferey L. Burgess, Karen Lutrick, Katherine D. Ellingson, Makiko Watanabe, Janko Nikolich-Zugich
Summary: Several studies have shown that the Omicron variant of the SARS-CoV-2 virus has a high ability to evade neutralizing antibodies. However, T cell memory exhibits a strong response against Omicron, with consistent IFN-gamma production similar to the response against the ancestral strain. There is a slight decrease in IL-2 or IL-21IFN-gamma-1 polyfunctional responses. Participants who received three doses of the mRNA vaccine had similar T cell responses to those who had recovered from COVID-19, and their responses were significantly higher than those who received two vaccine doses.
JOURNAL OF IMMUNOLOGY
(2022)
