Article
Immunology
Marya D. Zilberberg, Brian H. Nathanson, Kate Sulham, Andrew F. Shorr
Summary: This study examined the epidemiology and outcomes of two groups of UTI patients in the United States. The results showed that although the two groups had similar age distribution, catheter-associated UTI patients had higher comorbidity and hospital mortality, while non-catheter-associated UTI patients had higher rate of routine discharges home.
OPEN FORUM INFECTIOUS DISEASES
(2022)
Article
Public, Environmental & Occupational Health
M. J. Lydeamore, B. G. Mitchell, T. Bucknall, A. C. Cheng, P. L. Russo, A. J. Stewardson
Summary: This study estimates the burden of healthcare associated infections (HAIs) in Australian public hospitals using a standard international framework. The results show that there are approximately 170,574 HAIs occurring in adults admitted to public hospitals in Australia annually, resulting in 7583 deaths. Hospital acquired pneumonia is the most frequent HAI, followed by surgical site infections and urinary tract infections. The study highlights the high burden of HAIs in Australia and the need for continued investment in prevention efforts.
ANTIMICROBIAL RESISTANCE AND INFECTION CONTROL
(2022)
Article
Gastroenterology & Hepatology
Zheng-Hao Yu, Ming-Mei Du, Li Lin, Bo-Wei Liu, Yan-Ling Bai, Meng-Lin Liu, Jia-Xi Li, Qing-Bin Lu, Yun-Xi Liu, Hong-Wu Yao
Summary: In recent years, there has been a decreasing trend in postoperative healthcare-associated infections (HAIs) in patients undergoing pancreaticoduodenectomy (PD), especially in those who underwent open PD (OPD). Robotic PD (RPD) was significantly associated with reduced HAIs and length of stay, although it had higher costs.
JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY
(2023)
Article
Infectious Diseases
Mark H. Wilcox, Matthew Dryden
Summary: Healthcare-associated infections pose a threat to patient safety and require monitoring data and microbiological characteristics to guide and reduce incidence rates. Among these infections, skin and soft tissue infections are the most common, including surgical site infections and other healthcare-associated infections.
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
(2021)
Article
Public, Environmental & Occupational Health
N. Grae, A. Singh, D. Jowitt, A. Flynn, E. Mountier, G. Clendon, R. Barratt, B. Gibson, C. Williams, S. A. Roberts, A. J. Morris
Summary: This study aims to determine the epidemiology of healthcare-associated infections (HAIs), prevalence of medical devices, and microbiology of HAIs in adults in public hospitals in New Zealand. The findings revealed that 6.6% of the surveyed patients had HAIs, with surgical site infections, urinary tract infections, pneumonia, and bloodstream infections being the most common types. Device use accounted for 16% of the HAIs. The study highlights the importance of implementing proven multi-modal prevention interventions to reduce the burden of HAIs.
JOURNAL OF HOSPITAL INFECTION
(2023)
Article
Public, Environmental & Occupational Health
Huifang Huang, Kunhai Wu, Haiming Chen, Jing Wang, Lufei Chen, Zhirun Lai, Shuling Lin
Summary: This study evaluated the impact of control strategies during the COVID-19 pandemic on nosocomial infection surveillance in a regional maternity hospital. The results showed that the incidence of nosocomial infections in the hospital decreased during the COVID-19 pandemic, especially respiratory, gastrointestinal, and catheter-related infections.
FRONTIERS IN PUBLIC HEALTH
(2023)
Article
Multidisciplinary Sciences
Mathew Stracy, Olga Snitser, Idan Yelin, Yara Amer, Miriam Parizade, Rachel Katz, Galit Rimler, Tamar Wolf, Esma Herzel, Gideon Koren, Jacob Kuint, Betsy Foxman, Gabriel Chodick, Varda Shalev, Roy Kishony
Summary: Currently, the treatment of bacterial infections focuses on choosing antibiotics based on the susceptibility of the pathogen, but there is less attention given to the risk of treatment-induced resistance. By using genomic sequencing and machine learning analysis, it is possible to predict and minimize the emergence of resistance at the individual-patient level.
Article
Infectious Diseases
Raquel Bandeira da Silva, Mauro Jose Salles
Summary: This study identified independent risk factors associated with multidrug-resistant GNB prosthetic joint infection, including revision arthroplasty, postoperative hematoma, previous orthopaedic infection, and early infection. Extensively drug-resistant GNB and comorbidities were independently associated with higher treatment failure rates in MDR-GNB PJI.
Article
Medicine, General & Internal
Maskit Bar-Meir, Gali Pariente, Ayal Romem, Yonit Wiener-Well
Summary: The acceptance rate of latent tuberculosis infection (LTBI) treatment was very low among healthcare workers in the study. Focusing on educating healthcare workers is potentially the key step towards increasing the rate of LTBI treatment acceptance.
Article
Medicine, General & Internal
Usama Waqar, Maheen Mansoor, Asma Altaf Hussain Merchant, Ronika Devi Ukrani, Asad Saulat Fatimi, Manzar Abbas, Muskaan Abdul Qadir, Russell Seth Martins, Sehar Salim Virani, Faiqa Binte Aamir, Hamna Ganny, Javeria Tariq, Mabrooka Kazi, Muhammad Uzair, Muhammad Umar Mahar, Izza Tahir, Shaheer Ahmed, Daniyal Ali Khan, Hareem Rauf, Mahnoor Javaid, Momina Faisal, Sarim Raheel, Hajra Arshad, Muhammad Abbas Raza, Muhammad Jawad Amin Malik, Muhammad Ozair Awan, Amna Urooba, Mashal Murad Shah, Hina Inam, Abida Sattar, Aliya Begum Aziz, Erum Baig, Muhammad Shahzad Shamim, Nadeem Siddiqui, Amna Rehana Siddiqui, Sadaf Khan, Shahryar Noordin, Tabish Chawla, Syed Ather Enam
Summary: This study aims to identify the incidence and risk factors of surgical site infections (SSIs) in Pakistan and explore the existing SSI prevention practices. Currently, there is limited data available in Pakistan, and this study will provide valuable insights and evidence-based guidelines.
Article
Infectious Diseases
Pedro Maria Martinez Perez-Crespo, Joaquin Felipe Lanz-Garcia, Jose Bravo-Ferrer, Maria Luisa Canton-Bulnes, Adrian Sousa Dominguez, Josune Goikoetxea Aguirre, Jose Maria Reguera-Iglesias, Eva Leon Jimenez, Carlos Arminanzas Castillo, Maria Angeles Mantecon Vallejo, Teresa Marrodan Ciordia, Jonathan Fernandez Suarez, Lucia Boix-Palop, Jordi Cuquet Pedragosa, Alfredo Jover Saenz, Juan Sevilla Blanco, Fatima Galan-Sanchez, Clara Natera Kindelan, Alfonso del Arco Jimenez, Alberto Bahamonde-Carrasco, Alejandro Smithson Amat, David Vinuesa Garcia, Carmen Herrero Rodriguez, Isabel Maria Reche Molina, Ines Perez Camacho, Antonio Sanchez-Porto, Marcos Guzman Garcia, Berta Becerril Carral, Esperanza Merino de Lucas, Inmaculada Lopez-Hernandez, Jesus Rodriguez-Bano, Luis Eduardo Lopez-Cortes
Summary: The epidemiology of bloodstream infections in Spain was updated in this study, revealing significant differences between community-acquired, healthcare-associated, and hospital-acquired BSIs in demographics, underlying conditions, and etiology.
INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS
(2021)
Article
Ophthalmology
Johan Rasmus Simonsen, Asko Jarvinen, Kustaa Hietala, Valma Harjutsalo, Carol Forsblom, Per-Henrik Groop, Markku Lehto
Summary: The study found that bacterial infections are associated with an increased risk of incident severe diabetic retinopathy in individuals with type 1 diabetes.
BRITISH JOURNAL OF OPHTHALMOLOGY
(2021)
Article
Medicine, General & Internal
Unab Inayat Khan, Mahnoor Niaz, Iqbal Azam, Zahra Hasan, Imran Hassan, Syed Faisal Mahmood, Asad Ali
Summary: A study in Pakistan's healthcare system found that inactivated vaccines have limited effectiveness against SARS-CoV-2 variants of concern, suggesting the need for boosters or additional vaccination.
Article
Infectious Diseases
Mark Wilcox, Jean Li Yan, Pedro L. Gonzalez, Matthew Dryden, Gregory G. Stone, Michal Kantecki
Summary: This analysis evaluated the impact of underlying comorbidities on clinical outcomes in patients with complicated skin and soft tissue infections (cSSTIs) treated with ceftaroline fosamil compared to vancomycin plus aztreonam. Regardless of age and comorbidities such as diabetes, peripheral vascular disease, and cancer/malignancy, outcomes were similar between the treatment groups. Subgroup analyses showed consistent efficacy and safety results with those of the overall cSSTI population.
INFECTIOUS DISEASES AND THERAPY
(2022)
Article
Infectious Diseases
Ruth Gil-Prieto, Nizar Allouch, Isabel Jimeno, Valentin Hernandez-Barrera, Raquel Arguedas-Sanz, Angel Gil-de-Miguel
Summary: Pneumococcal infection in Spain has a high impact on health, with 253,899 hospitalizations occurring from 2016 to 2020. The average age of patients was 67 years old and the average length of hospitalization was 12.72 days. The annual hospitalization rate was 10.84 per 10,000 population, increasing with age and reaching 65.75 per 10,000 population in individuals aged over 85. The case-fatality rate was 14.07%, with the highest rates seen in sepsis. The annual cost of hospitalizations exceeded EUR 359 million.