Deficiency of Double-Strand DNA Break Repair Does Not Impair Mycobacterium tuberculosis Virulence in Multiple Animal Models of Infection

Either Non-Homologous Ends Joining or Homologous Recombination Is Required to Repair Double-Strand Breaks in the Genome of Macrophage-Internalized Mycobacterium tuberculosis

(2014) Anna Brzostek et al.   PLoS One

A dual role for mycobacterial RecO in RecA-dependent homologous recombination and RecA-independent single-strand annealing

(2013) Richa Gupta et al.   NUCLEIC ACIDS RESEARCH

Evaluation of a Mouse Model of Necrotic Granuloma Formation Using C3HeB/FeJ Mice for Testing of Drugs against Mycobacterium tuberculosis

(2012) Emily R. Driver et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Dose-Ranging Comparison of Rifampin and Rifapentine in Two Pathologically Distinct Murine Models of Tuberculosis

(2012) Ian M. Rosenthal et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Important Role for Mycobacterium tuberculosis UvrD1 in Pathogenesis and Persistence apart from Its Function in Nucleotide Excision Repair

(2012) J. Houghton et al.   JOURNAL OF BACTERIOLOGY

Dose-Dependent Activity of Pyrazinamide in Animal Models of Intracellular and Extracellular Tuberculosis Infections

(2011) Zahoor Ahmad et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Mouse Model of Necrotic Tuberculosis Granulomas Develops Hypoxic Lesions

(2011) Jamie Harper et al.   JOURNAL OF INFECTIOUS DISEASES

Use of whole genome sequencing to estimate the mutation rate of Mycobacterium tuberculosis during latent infection

(2011) Christopher B Ford et al.   NATURE GENETICS

The Mechanism of Double-Strand DNA Break Repair by the Nonhomologous DNA End-Joining Pathway

(2010) Michael R. Lieber   Annual Review of Biochemistry

DNA repair systems and the pathogenesis ofMycobacterium tuberculosis: varying activities at different stages of infection

(2010) Alina E. Gorna et al.   CLINICAL SCIENCE

The potent bactericidal activity of streptomycin in the guinea pig model of tuberculosis ceases due to the presence of persisters

(2010) Z. Ahmad et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Mycobacteria exploit three genetically distinct DNA double-strand break repair pathways

(2010) Richa Gupta et al.   MOLECULAR MICROBIOLOGY

Noninvasive Pulmonary [18F]-2-Fluoro-Deoxy-D-Glucose Positron Emission Tomography Correlates with Bactericidal Activity of Tuberculosis Drug Treatment

(2009) S. L. Davis et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Biphasic Kill Curve of Isoniazid Reveals the Presence of Drug‐Tolerant, Not Drug‐Resistant,Mycobacterium tuberculosisin the Guinea Pig

(2009) Zahoor Ahmad et al.   JOURNAL OF INFECTIOUS DISEASES

Phosphate Depletion: A Novel Trigger forMycobacterium tuberculosisPersistence

(2009) Dalin Rifat et al.   JOURNAL OF INFECTIOUS DISEASES

A replication clock for Mycobacterium tuberculosis

(2009) Wendy P Gill et al.   NATURE MEDICINE

The Base Excision Repair System of Salmonella enterica serovar Typhimurium Counteracts DNA Damage by Host Nitric Oxide

(2009) Anthony R. Richardson et al.   PLoS Pathogens

The pathways and outcomes of mycobacterial NHEJ depend on the structure of the broken DNA ends

(2008) J. Aniukwu et al.   GENES & DEVELOPMENT

Tuberculous Granulomas Are Hypoxic in Guinea Pigs, Rabbits, and Nonhuman Primates

(2008) L. E. Via et al.   INFECTION AND IMMUNITY

Metronidazole Lacks Activity againstMycobacterium tuberculosisin an In Vivo Hypoxic Granuloma Model of Latency

(2008) Lee G. Klinkenberg et al.   JOURNAL OF INFECTIOUS DISEASES

Helicobacter pyloriAddAB helicase-nuclease and RecA promote recombination-related DNA repair and survival during stomach colonization

(2008) Susan K. Amundsen et al.   MOLECULAR MICROBIOLOGY