Metal-Mediated Modulation of Streptococcal Cysteine Protease Activity and Its Biological Implications

Toxic Shock Syndrome

(2013) Donald E. Low   CRITICAL CARE CLINICS

Zinc-mediated Allosteric Inhibition of Caspase-6

(2012) Elih M. Velázquez-Delgado et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ultrahigh and High Resolution Structures and Mutational Analysis of MonomericStreptococcus pyogenesSpeB Reveal a Functional Role for the Glycine-rich C-terminal Loop

(2012) Gonzalo E. González-Páez et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mechanism of zinc-mediated inhibition of caspase-9

(2012) Kristen L. Huber et al.   PROTEIN SCIENCE

Cysteine proteinase SpeB from Streptococcus pyogenes – a potent modifier of immunologically important host and bacterial proteins

(2011) Daniel C. Nelson et al.   BIOLOGICAL CHEMISTRY

Individual Genetic Variations Directly Effect Polarization of Cytokine Responses to Superantigens Associated with Streptococcal Sepsis: Implications for Customized Patient Care

(2011) M. M. Nooh et al.   JOURNAL OF IMMUNOLOGY

From transcription to activation: how group A streptococcus, the flesh-eating pathogen, regulates SpeB cysteine protease production

(2011) Ronan K. Carroll et al.   MOLECULAR MICROBIOLOGY

Molecular insight into invasive group A streptococcal disease

(2011) Jason N. Cole et al.   NATURE REVIEWS MICROBIOLOGY

Dispersal of Group A Streptococcal Biofilms by the Cysteine Protease SpeB Leads to Increased Disease Severity in a Murine Model

(2011) Kristie L. Connolly et al.   PLoS One

Getting under the Skin: The Immunopathogenesis ofStreptococcus pyogenesDeep Tissue Infections

(2010) Linda Johansson et al.   CLINICAL INFECTIOUS DISEASES

Loss of the Group A Streptococcus Regulator Srv Decreases Biofilm Formation In Vivo in an Otitis Media Model of Infection

(2010) A. L. Roberts et al.   INFECTION AND IMMUNITY

FINDSITE: a combined evolution/structure-based approach to protein function prediction

(2009) J. Skolnick et al.   BRIEFINGS IN BIOINFORMATICS

Solution Structure and Backbone Dynamics of Streptopain

(2009) Chih-Chieh Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structure of the Mature Streptococcal Cysteine Protease Exotoxin mSpeB in Its Active Dimeric Form

(2009) Johan G. Olsen et al.   JOURNAL OF MOLECULAR BIOLOGY

Prediction of 3D metal binding sites from translated gene sequences based on remote-homology templates

(2008) Ronen Levy et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS