Type 2 Innate Immunity in Helminth Infection Is Induced Redundantly and Acts Autonomously following CD11c+Cell Depletion

Nonredundant Roles of Basophils in Immunity

(2011) Hajime Karasuyama et al.   Annual Review of Immunology

Immune modulation and modulators in Heligmosomoides polygyrus infection

(2011) Rick M. Maizels et al.   EXPERIMENTAL PARASITOLOGY

Chronic Helminth Infection Promotes Immune Regulation In Vivo through Dominance of CD11cloCD103- Dendritic Cells

(2011) K. A. Smith et al.   JOURNAL OF IMMUNOLOGY

Basophils Are the Major Producers of IL-4 during Primary Helminth Infection

(2011) N. van Panhuys et al.   JOURNAL OF IMMUNOLOGY

Impaired Basophil Induction Leads to an Age-Dependent Innate Defect in Type 2 Immunity during Helminth Infection in Mice

(2011) H. J. Nel et al.   JOURNAL OF IMMUNOLOGY

Proteomic analysis of secretory products from the model gastrointestinal nematode Heligmosomoides polygyrus reveals dominance of Venom Allergen-Like (VAL) proteins

(2011) James P. Hewitson et al.   Journal of Proteomics

Genetic analysis of basophil function in vivo

(2011) Brandon M Sullivan et al.   NATURE IMMUNOLOGY

Eosinophils Sustain Adipose Alternatively Activated Macrophages Associated with Glucose Homeostasis

(2011) D. Wu et al.   SCIENCE

Helminths and dendritic cells: Sensing and regulating via pattern recognition receptors, Th2 and Treg responses

(2010) Bart Everts et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Basophils Orchestrate Chronic Allergic Dermatitis and Protective Immunity against Helminths

(2010) Caspar Ohnmacht et al.   IMMUNITY

CD11c depletion severely disrupts Th2 induction and development in vivo

(2010) Alexander T. Phythian-Adams et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Inflammatory dendritic cells—not basophils—are necessary and sufficient for induction of Th2 immunity to inhaled house dust mite allergen

(2010) Hamida Hammad et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Basophils Amplify Type 2 Immune Responses, but Do Not Serve a Protective Role, during Chronic Infection of Mice with the Filarial Nematode Litomosoides sigmodontis

(2010) M. N. Torrero et al.   JOURNAL OF IMMUNOLOGY

Nuocytes represent a new innate effector leukocyte that mediates type-2 immunity

(2010) Daniel R. Neill et al.   NATURE

IL25 elicits a multipotent progenitor cell population that promotes TH2 cytokine responses

(2010) Steven A. Saenz et al.   NATURE

The T helper type 2 response to cysteine proteases requires dendritic cell–basophil cooperation via ROS-mediated signaling

(2010) Hua Tang et al.   NATURE IMMUNOLOGY

Systemically dispersed innate IL-13-expressing cells in type 2 immunity

(2010) A. E. Price et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Emerging roles of basophils in protective immunity against parasites

(2010) Hajime Karasuyama et al.   TRENDS IN IMMUNOLOGY

Heligmosomoides polygyrus: one species still

(2010) Rick M. Maizels et al.   TRENDS IN PARASITOLOGY

Homeostasis of dendritic cells in lymphoid organs is controlled by regulation of their precursors via a feedback loop

(2009) K. Hochweller et al.   BLOOD

Intestinal epithelial cell secretion of RELM-β protects against gastrointestinal worm infection

(2009) De'Broski R. Herbert et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Omega-1, a glycoprotein secreted bySchistosoma mansonieggs, drives Th2 responses

(2009) Bart Everts et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The major component in schistosome eggs responsible for conditioning dendritic cells for Th2 polarization is a T2 ribonuclease (omega-1)

(2009) Svenja Steinfelder et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Cutting Edge: Basophils Are Transiently Recruited into the Draining Lymph Nodes during Helminth Infection via IL-3, but Infection-Induced Th2 Immunity Can Develop without Basophil Lymph Node Recruitment or IL-3

(2009) S. Kim et al.   JOURNAL OF IMMUNOLOGY

Basophils Protect against Reinfection with Hookworms Independently of Mast Cells and Memory Th2 Cells

(2009) Caspar Ohnmacht et al.   JOURNAL OF IMMUNOLOGY

MIF homologues from a filarial nematode parasite synergize with IL-4 to induce alternative activation of host macrophages

(2009) Lidia Prieto-Lafuente et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Helminth immunoregulation: The role of parasite secreted proteins in modulating host immunity

(2009) James P. Hewitson et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

Innate production of TH2 cytokines by adipose tissue-associated c-Kit+Sca-1+ lymphoid cells

(2009) Kazuyo Moro et al.   NATURE

MHC class II–dependent basophil–CD4+ T cell interactions promote TH2 cytokine–dependent immunity

(2009) Jacqueline G Perrigoue et al.   NATURE IMMUNOLOGY

Basophils function as antigen-presenting cells for an allergen-induced T helper type 2 response

(2009) Caroline L Sokol et al.   NATURE IMMUNOLOGY

Basophil effector function and homeostasis during helminth infection

(2008) C. Ohnmacht et al.   BLOOD

A novel CD11c.DTR transgenic mouse for depletion of dendritic cells reveals their requirement for homeostatic proliferation of natural killer cells

(2008) Kristin Hochweller et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Th2 Cytokine-Induced Alterations in Intestinal Smooth Muscle Function Depend on Alternatively Activated Macrophages

(2008) Aiping Zhao et al.   GASTROENTEROLOGY

Functional Analysis of Effector and Regulatory T Cells in a Parasitic Nematode Infection

(2008) S. Rausch et al.   INFECTION AND IMMUNITY

Alarming dendritic cells for Th2 induction

(2008) Andrew S. MacDonald et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Basophils enhance immunological memory responses

(2008) Andrea Denzel et al.   NATURE IMMUNOLOGY