Neutralizing Antibodies Elicited by a Novel Detoxified Pneumolysin Derivative, PlyD1, Provide Protection against Both Pneumococcal Infection and Lung Injury

Danger Signaling through the Inflammasome Acts as a Master Switch between Tolerance and Sensitization

(2014) Hideki Watanabe et al.   JOURNAL OF IMMUNOLOGY

Structure-guided Antigen Engineering Yields Pneumolysin Mutants Suitable for Vaccination against Pneumococcal Disease

(2011) Eliud O. Oloo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A protein-based pneumococcal vaccine protects rhesus macaques from pneumonia after experimental infection with Streptococcus pneumoniae

(2011) Philippe Denoël et al.   VACCINE

Changes in Astrocyte Shape Induced by Sublytic Concentrations of the Cholesterol-Dependent Cytolysin Pneumolysin Still Require Pore-Forming Capacity

(2011) Christina Förtsch et al.   Toxins

Identification of novel pneumolysin alleles from paediatric carriage isolates of Streptococcus pneumoniae

(2010) J. M. C. Jefferies et al.   JOURNAL OF MEDICAL MICROBIOLOGY

Protection against Pneumococcal Colonization and Fatal Pneumonia by a Trivalent Conjugate of a Fusion Protein with the Cell Wall Polysaccharide

(2009) Y.-J. Lu et al.   INFECTION AND IMMUNITY

Pneumolysin generates multiple conductance pores in the membrane of nucleated cells

(2008) Rana G. El-Rachkidy et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Pneumolysin: A Double-Edged Sword During the Host-Pathogen Interaction

(2008) Helen Marriott et al.   CURRENT MOLECULAR MEDICINE