Role of Interleukin-23 (IL-23) Receptor Signaling for IL-17 Responses in Human Lyme Disease

LY2439821, a humanized anti-interleukin-17 monoclonal antibody, in the treatment of patients with rheumatoid arthritis: A phase I randomized, double-blind, placebo-controlled, proof-of-concept study

(2010) M. C. Genovese et al.   ARTHRITIS AND RHEUMATISM

Role of osteopontin in synovial Th17 differentiation in rheumatoid arthritis

(2010) Guangjie Chen et al.   ARTHRITIS AND RHEUMATISM

Borrelia species induce inflammasome activation and IL-17 production through a caspase-1-dependent mechanism

(2010) Marije Oosting et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Inflammation in the Central Nervous System and Th17 Responses Are Inhibited by IFN- -Induced IL-18 Binding Protein

(2010) J. M. Millward et al.   JOURNAL OF IMMUNOLOGY

Recognition ofBorrelia burgdorferiby NOD2 Is Central for the Induction of an Inflammatory Reaction

(2010) Marije Oosting et al.   JOURNAL OF INFECTIOUS DISEASES

Early Production of IL-22 but Not IL-17 by Peripheral Blood Mononuclear Cells Exposed to live Borrelia burgdorferi: The Role of Monocytes and Interleukin-1

(2010) Malte Bachmann et al.   PLoS Pathogens

Ustekinumab: Lessons Learned from Targeting Interleukin-12/23p40 in Immune-Mediated Diseases

(2009) Michael Elliott et al.   Annals of the New York Academy of Sciences

Inhibition of ERK MAPK Suppresses IL-23- and IL-1-Driven IL-17 Production and Attenuates Autoimmune Disease

(2009) C. F. Brereton et al.   JOURNAL OF IMMUNOLOGY

Evidence for association of an interleukin 23 receptor variant independent of the R381Q variant with rheumatoid arthritis

(2008) J E Hollis-Moffatt et al.   ANNALS OF THE RHEUMATIC DISEASES

Borrelia burgdorferiNapA-driven Th17 cell inflammation in lyme arthritis

(2008) Gaia Codolo et al.   ARTHRITIS AND RHEUMATISM

Interleukin-23 Is Required for Development of Arthritis in Mice Vaccinated and Challenged with Borrelia Species

(2008) N. J. Kotloski et al.   Clinical and Vaccine Immunology

Role of IL-17, transforming growth factor-β, and IL-6 in the development of arthritis and production of anti-outer surface protein A borreliacidal antibodies inBorrelia-vaccinated and -challenged mice

(2008) Dean T. Nardelli et al.   FEMS IMMUNOLOGY AND MEDICAL MICROBIOLOGY

Crystal Structures of the Pro-Inflammatory Cytokine Interleukin-23 and Its Complex with a High-Affinity Neutralizing Antibody

(2008) Brian M. Beyer et al.   JOURNAL OF MOLECULAR BIOLOGY