Review
Pharmacology & Pharmacy
Siu Kan Law, Yanping Wang, Xinchen Lu, Dawn Ching Tung Au, Wesley Yeuk Lung Chow, Albert Wing Nang Leung, Chuanshan Xu
Summary: Obesity is a global health threat and traditional Chinese medicine offers a potential solution, but there are still challenges that need to be addressed. Prodrugs could help overcome the deficiencies and provide insights for designing effective treatments for obesity.
FRONTIERS IN PHARMACOLOGY
(2022)
Article
Food Science & Technology
Asma Alkuwari, Zahoor Ul Hassan, Randa Zeidan, Roda Al-Thani, Samir Jaoua
Summary: Fungal infections and mycotoxins were found in various types of marketed cereals, with Aspergillus spp. being the most frequent contaminating fungi. The levels of mycotoxins detected were within the EU permissible limits. Additionally, the yeast Cyberlindnera jadinii was found to have significant biocontrol ability against certain toxigenic fungal strains.
Article
Environmental Sciences
Eman Khalifa, Marwa T. Mohesien, Monga I. Mossa, Magdalena Piekutowska, Amnah Mohammed Alsuhaibani, Basel A. Abdel-Wahab, Sotohy Ahmed Sotohy, Soumya Ghosh, Yosra A. Helmy, Mohamed Hussein, Ahmed M. Abdel-Azeem
Summary: This study investigated the abundance of toxigenic fungi and mycotoxins in animal feedstuff samples in Egypt. The majority of samples were contaminated with fungi, mainly belonging to the genus Aspergillus. Levels of aflatoxins were generally below permissible limits set by international authorities or Egyptian guidelines.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2022)
Article
Chemistry, Analytical
Jianru Hou, Changliang Yao, Yun Li, Lin Yang, Xuebing Chen, Min Nie, Hua Qu, Shen Ji, De-an Guo
Summary: In this study, a MS-feature-based medicinal plant database-driven strategy was proposed for quick and automatic interpretation of the ingredients of Chinese medicine prescriptions (CMPs). A single herb database was constructed, and the data of CMPs were imported into a self-built searching program to achieve fast and automated identification. The strategy was optimized and validated, and proved to be a promising and universal approach for identifying the ingredients of CMPs.
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
(2023)
Article
Engineering, Environmental
Palanivel Sathishkumar, Kannan Mohan, Ramakrishnan Anu Alias Meena, Murugesan Balasubramanian, Loganathan Chitra, Abirami Ramu Ganesan, Thayumanavan Palvannan, Satinder Kaur Brar, Feng Long Gu
Summary: This paper reviews the distribution and adverse ecological impact of diclofenac in diverse environments, emphasizing its potential dangers to human and animal health, as well as the importance of green remediation in combating its toxicity.
JOURNAL OF HAZARDOUS MATERIALS
(2021)
Review
Environmental Sciences
Yuwen Chen, Junyi Zou, Hui Sun, Jihong Qin, Jiyuan Yang
Summary: In recent decades, there has been a comprehensive review of public reports on metals in traditional Chinese medicinal materials (TCMM). The distribution of metals in different medicinal parts has been analyzed, with lead mainly distributed in leaves and cadmium mainly distributed in flowers and fruits, stems and leaves. The risk of metal residues is highest in the Qinghai-Tibet Plateau, south China, and southwest China, with herba-type medicinal materials having the highest risk of metal content.
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
(2021)
Review
Neurosciences
Hossein Akbarialiabad, Mohammad Dahri Dahroud, Mohammad M. Khazaei, Saeed Razmeh, Mohammad M. Zarshenas
Summary: This review compiled evidence on the neurological activities, mechanisms of action, and clinical properties of green tea and its related compounds, suggesting their potential as neuro-effective agents with antidepressant, anti-neurodegenerative, and neuroprotective effects. Further research, including standardized clinical trials and pharmacokinetic studies, is needed to safely introduce green tea as a beneficial medicinal food for neurological disorders.
CURRENT NEUROPHARMACOLOGY
(2021)
Review
Pharmacology & Pharmacy
Enming Zhang, Xin Ji, Fang Ouyang, Yang Lei, Shun Deng, Haibo Rong, Xuangen Deng, Hai Shen
Summary: Entomoceuticals are a subset of pharmaceuticals derived from insects. Their therapeutic effect has been validated through the use of folk medicines derived from insect secretions, body parts, and active ingredients. Insects have been extensively used in traditional Chinese medicine and are also exploited for their health benefits and nutritional value in the food industry. This review focuses on 12 insect species used in traditional Chinese herbal formulae that have not been thoroughly studied for their biological properties, combining entomoceutical knowledge with recent advances in insect omics.
FRONTIERS IN PHARMACOLOGY
(2023)
Review
Plant Sciences
Yin Xiong, Minghui Li, Pengyue Sun, Wen Liang, Ryan G. Hornbeck, Xiaoyan Che, Cheng Rao, Ye Zhao, Liqun Guo, Yan Huang, Hua Yang, Ping Li, Burt H. Kroes, Xiuming Cui, Gerhard Franz, Mei Wang
Summary: With increasing demand for natural and effective health products in Europe, the market for herbal products is growing. However, there are limited registrations of Chinese herbal medicine (CHM) products in the European Union (EU), posing challenges for pharmaceutical companies seeking market access. To successfully register CHM products, companies are advised to comply with EU regulations, consider the medication habits and pharmaceutical needs of the European market, and collaborate with local organizations in Europe.
Review
Biochemistry & Molecular Biology
Stephen T. Deyrup, Natalie C. Stagnitti, Mackenzie J. Perpetua, Siu Wah Wong-Deyrup
Summary: Traditional Chinese medicine (TCM) has been a primary source of medical treatment in East Asia for thousands of years, incorporating a wide variety of materia medica including insects like beetles. Research found that 48 species of beetles from 34 genera in TCM contain 129 chemical constituents with documented uses in Traditional Korean Medicine (TKM).
BIOMOLECULES & THERAPEUTICS
(2021)
Article
Chemistry, Analytical
Mengzhen Cheng, Changliang Yao, Yun Li, Zhenwei Li, Haojv Li, Shuai Yao, Hua Qu, Jiayuan Li, Wenlong Wei, Jianqing Zhang, De-an Guo
Summary: The strategy integrating in-depth profiling, chemical marker selection, and selected detection was proven effective in authenticating paeony root in prescriptions, demonstrating practical application value for improving the quality of prescriptions.
JOURNAL OF SEPARATION SCIENCE
(2021)
Review
Integrative & Complementary Medicine
Qi Xiao, Xinlu Mu, Jiushi Liu, Bin Li, Haitao Liu, Bengang Zhang, Peigen Xiao
Summary: This article comprehensively reviewed the application of plant metabolomics in the quality control of Chinese medicinal materials, highlighting the techniques of MS and NMR. The purpose is to promote the optimization of the quality control system and propose an overall quality control approach based on plant metabolomics and multidisciplinary methods.
Review
Medicine, Research & Experimental
Yuan Lou, Maoqiang Ma, Yanan Jiang, Haoqun Xu, Zu Gao, Lin Gao, Yuan Wang
Summary: Stroke is a serious threat to human survival and health, and its pathological mechanism involves complex regulated cell death modalities. Ferroptosis, a novel form of regulated cell death associated with iron-dependent accumulation of lipid peroxides, has been found to be closely associated with the prognosis and outcome of stroke. Traditional Chinese medicine, with its multi-component, multi-pathway, and multi-target characteristics, has unique advantages and prospects for stroke prevention and treatment.
BIOMEDICINE & PHARMACOTHERAPY
(2022)
Article
Pharmacology & Pharmacy
Zheng Li, Biao Qu, Lei Zhou, Hongwei Chen, Jue Wang, Wei Zhang, Caifa Chen
Summary: In this study, a total of 34 phytochemical components were detected in the OSB extract using liquid chromatography coupled with mass spectrometry. Core constituents including tanshinone IIA, sinensetin, salvianolic acid B, rosmarinic acid, and salvigenin were screened out as efficacy markers of OSB, providing a promising direction for future research on the quality control and pharmacological mechanism of OSB.
FRONTIERS IN PHARMACOLOGY
(2021)
Review
Endocrinology & Metabolism
Maoying Wei, Xingxing Liu, Zhijuan Tan, Xiaochan Tian, Mingdi Li, Junping Wei
Summary: Diabetic nephropathy (DN) is a serious complication of diabetes and a leading cause of death in diabetes patients with end-stage renal disease. Ferroptosis, a newly discovered programmed cell death pattern characterized by excessive accumulation of intracellular lipid peroxides dependent on iron ions, has been shown to play an important role in the onset and development of DN. Chinese herbal medicine, with its long history and definite curative effect, has the potential to modulate ferroptosis in renal intrinsic cells and improve DN. This review outlines the key regulators and pathways of ferroptosis in DN and summarizes the herbs, mainly monomers and extracts, that target the inhibition of ferroptosis.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Article
Agricultural Engineering
Jingmo Zhou, Shubin Wu, Ying Liu
Summary: Expenditure isolation of lignin and the understanding of its structural variations during different isolation processes are crucial for the high-value utilization of lignin. This study proposed a green deep eutectic solvent (DES) consisting of choline chloride, ethylene glycol, and 4-chlorobenzene sulfonic acid for rapid lignin separation from poplar. The structural variations of DES lignin and its relationship with alkali pre-extraction of hemicellulose were investigated. The results showed that alkali pretreatment enhanced the DES separation of lignin and promoted the cleavage of specific linkages, resulting in reduced molecular weight and thermal stability of isolated DES lignin. Moreover, DES lignin obtained from integrated utilization displayed higher purity and S/G ratio compared to lignin obtained from direct DES treatment.
INDUSTRIAL CROPS AND PRODUCTS
(2024)
Article
Agricultural Engineering
Yuping Li, Ziyan Xie, Yun Huang, Jiangyi Zeng, Chao Yang, Ling Yuan, Ying Wang, Yongqing Li
Summary: In this study, the characteristic flavonoids (CFs) of three licorice species were identified through integrated metabolic and transcriptomic analysis. The key regulators of CF biosynthesis were also identified. These findings provide valuable information for understanding the biosynthesis of CFs and future breeding of Glycyrrhiza varieties.
INDUSTRIAL CROPS AND PRODUCTS
(2024)
Article
Agricultural Engineering
Xianjie Pan, Zhaoyi Luo, Fanqi Liu, Quanqian Yi, Yanning Zeng
Summary: This study presents a novel strategy for fabricating fully bio-based epoxy vitrimers using peach gum and itaconic acid, which exhibit superior mechanical properties and thermostability. The materials were characterized and the self-healing and recycling capabilities were evaluated. The results demonstrate the potential of using these materials for sustainable industrial applications.
INDUSTRIAL CROPS AND PRODUCTS
(2024)
Article
Agricultural Engineering
Mohsen Sabzi-Nojadeh, Mohammad Pouresmaeil, Mina Amani, Mehdi Younessi-Hamzekhanlu, Filippo Maggi
Summary: This study shows that inoculating Summer savory plants with endophytic fungus Trichoderma harzianum can improve plant growth and increase salt tolerance. The fungus enhances growth, restores chlorophyll and antioxidant levels, reduces harmful substances, and increases proline and soluble sugar levels, thereby increasing crop productivity in saline conditions.
INDUSTRIAL CROPS AND PRODUCTS
(2024)
Article
Agricultural Engineering
Yu Liu, Lei Li, Aichen Zhao, Xiuming Song, Lulu Wei, Mengdi Fang, Chuchu Zheng, Xiaodong Zhu
Summary: This study investigates the impact of peppermint essential oil microcapsules on the unpleasant odor emissions from wax oil coated wood products. The results show that microcapsules can improve the time and stability of odor release.
INDUSTRIAL CROPS AND PRODUCTS
(2024)
Article
Agricultural Engineering
Mesut Budak, Mirac Kilic, Hikmet Guenal, Ismail Velik, Mesut Sirri
Summary: This study assessed land suitability for rapeseed production using topography, climate, and soil data by analytical hierarchy process (AHP) and the Mamdani Fuzzy Inference System (MFIS). The study area covered land in the Diyarbakir province of southeastern Turkiye. The results indicated the proportions of different land suitability classes and showed the compatibility of AHP and MFIS methods in assessing suitability.
INDUSTRIAL CROPS AND PRODUCTS
(2024)
Article
Agricultural Engineering
Rui Tian, Yue Liu, Chao Wang, Weikun Jiang, Srinivas Janaswamy, Guihua Yang, Xingxiang Ji, Gaojin Lyu
Summary: In this study, hollow and solid lignin nanoparticles were synthesized through self-assembly and their application in PVA nanocomposite films was investigated. The results showed that the presence of hollow lignin nanoparticles in the films resulted in a room-like network structure, while the solid lignin nanoparticles induced different structural changes. The inclusion of LNPs improved the mechanical properties of the films, and both types of LNPs exhibited good hydrophobicity.
INDUSTRIAL CROPS AND PRODUCTS
(2024)
Article
Agricultural Engineering
Marcos Vinicius Silva de Andrade, Simone Ribeiro Lucho, Renato Delmondez de Castro, Paulo Roberto Ribeiro
Summary: Stevia rebaudiana Bertoni, commonly known as stevia, is a widely cultivated shrub with highly sweetening metabolites. It has gained significant interest in the food and beverage industries due to its extremely sweet taste and various health benefits. Researchers are currently focused on studying biotechnological strategies to enhance the biosynthesis of stevia plant metabolites for improved cultivation and production.
INDUSTRIAL CROPS AND PRODUCTS
(2024)
Article
Agricultural Engineering
Eleonora Cintura, Paulina Faria, Luisa Molari, Luca Barbaresi, Dario D'Orazio, Lina Nunes
Summary: This study investigated the properties of Arundo donax as a building material and found that it has strong adaptability, high hygroscopicity, and unique sound absorption behavior. The mechanical tests also demonstrated the applicability of the Arundo donax-based composite. This opens up new possibilities for the further application of Arundo donax-based materials.
INDUSTRIAL CROPS AND PRODUCTS
(2024)
Article
Agricultural Engineering
Stiina Kotiranta, Juha-Matti Pihlava, Titta Kotilainen, Pauliina Palonen
Summary: The effect of light spectra, particularly far-red and short wavelength radiation, on the growth and secondary metabolites of cannabis is significant. Altering the R:FR ratio can increase the concentration and yield of secondary metabolites, while short wavelength radiation does not significantly affect plant morphology and secondary metabolite concentrations.
INDUSTRIAL CROPS AND PRODUCTS
(2024)
Article
Agricultural Engineering
Xuze Liu, Fangmin Liang, Jinyuan Cheng, Xuelian Zhou, Jia Wang, Guigan Fang, Kuizhong Shen, Xianzhi Meng, Chen Huang, Arthur J. Ragauskas
Summary: A novel Na2S-facilitated DES pretreatment method was proposed to fractionate moso bamboo, which achieved high lignin removal and preserved most cellulose and hemicellulose with excellent enzymatic digestibility.
INDUSTRIAL CROPS AND PRODUCTS
(2024)
Article
Agricultural Engineering
Zechun Ren, Xinyuan Zhou, Kejiao Ding, Tong Ji, Hao Sun, Xiang Chi, Yunzhao Wei, Min Xu
Summary: This study prepared a thermal/magnetic/light-triggered multi-stimuli responsive shape memory polymer composite with excellent properties by adding magnetic nanoparticles into a polyurethane composite. The composite showed high shape recovery rate, fast response behavior, and suitability for 3D printing. Controllable external stimuli allowed for dynamic, remote, and precise control of 4D transformations. This work is significant for the design of smart materials and devices.
INDUSTRIAL CROPS AND PRODUCTS
(2024)
Article
Agricultural Engineering
Yurany Camacho Ardila, Jaiver Efren Jaimes Figueroa, Maria Regina Wolf Maciel
Summary: The higher heating value (HHV) and elemental composition are important properties of biomass, and their prediction using proximate and ultimate analysis is accurate.
INDUSTRIAL CROPS AND PRODUCTS
(2024)
Article
Agricultural Engineering
Xiaohan Chen, Xianke Wang, Lili Shang, Xinxin Ma, Changhua Fang, Benhua Fei, Huanrong Liu, Shuqin Zhang
Summary: This study focuses on the comprehensive characterization of the three-dimensional (3D) structure of bamboo parenchyma and the evaluation of its tensile and compressive properties, as well as the analysis of its failure mechanisms. The study found that the measured tensile strength and elastic modulus of the parenchyma tissue are 48.81 MPa and 706.48 MPa, respectively. Compression failure modes in parenchyma tissue encompass compression bending and cell fracture, shear failure of the middle lamella, and detachment and debonding of the cell wall.
INDUSTRIAL CROPS AND PRODUCTS
(2024)
Article
Agricultural Engineering
Tianfeng Liu, Yuxin Liu, Yunlin Fu, Mengji Qiao, Penglian Wei, Zhigao Liu, Yingjian Li
Summary: This study explored the formation mechanism of agarwood induced by fungus and its potential application in high-quality and high-yielding agarwood production. The results showed that the transition layer played a critical role in the continuous accumulation of agarwood, and the parenchyma cells of the xylem rays and interxylary phloem were the main action site of fungus. The accumulation and distribution of chemical composition in different layers were also investigated. The study identified the drivers of specific compounds and provided a theoretical foundation for future agarwood production.
INDUSTRIAL CROPS AND PRODUCTS
(2024)