Article
Medicine, General & Internal
Ming-Ju Wu, Shang-Feng Tsai
Summary: This study analyzed the association between the definitions of acute kidney injury (AKI) and different stages of chronic kidney disease after intravenous administration of iodinated contrast medium. The results showed a significant increase in contrast-associated AKI from stage 3A onward in chronic kidney disease patients.
Article
Radiology, Nuclear Medicine & Medical Imaging
Tse-Hsuan Su, Chih-Huang Hsieh, Yi-Ling Chan, Yon-Cheong Wong, Chang-Fu Kuo, Chih-Huang Li, Cheng-Chia Lee, Hsien-Yi Chen
Summary: The study in Taiwanese patients found that contrast-enhanced CT was associated with a higher risk of acute kidney injury and further hemodialysis in patients with impaired kidney function, but not in those with normal kidney function.
Article
Cardiac & Cardiovascular Systems
Mei-Yi Wu, Tzu-Ting Chen, Mai-Szu Wu, Yu-Kang Tu
Summary: This study found that patients with CKD and CHF have a significantly high risk of acute-temporary or chronic dialysis after radio-contrast medium exposure. Strategies are needed to reduce this risk, especially in these patient populations.
INTERNATIONAL JOURNAL OF CARDIOLOGY
(2021)
Article
Biochemistry & Molecular Biology
Pai-Chin Hsu, Chih-Han Liu, Wen-Chin Lee, Chien-Hsing Wu, Chien-Te Lee, Chien-Hao Su, Yu-Chin Lily Wang, Kai-Fan Tsai, Terry Ting-Yu Chiou
Summary: This study found that the use of offending drugs, AKI severity, and early dialysis requirement were independent predictors of AKD severity. Higher AKD severity was associated with negative outcomes in post-AKI patients.
Article
Food Science & Technology
Inga Chomicka, Marlena Kwiatkowska, Alicja Lesniak, Jolanta Malyszko
Summary: This study analyzed all computed tomographies performed in 2019 in a clinic, finding that post-contrast acute kidney injury was more common in the non-enhanced CT population. The results of the study suggest that the use of contrast agents does not pose a significant risk to patients, even those with chronic kidney disease, and therefore the fear of using contrast agents is unjustified.
Review
Medicine, General & Internal
Hanna Cholerzynska, Wiktoria Zasada, Hanna Michalak, Milosz Miedziaszczyk, Andrzej Oko, Ilona Idasiak-Piechocka
Summary: Acute kidney injury (AKI) and sudden exacerbation of chronic kidney disease (CKD) often require urgent kidney replacement therapy (UKRT). Peritoneal dialysis (PD) is seen as a viable option for managing these patients. This review examines recent literature on the clinical outcomes of urgent-start peritoneal dialysis (USPD) in CKD and AKI.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Ping Yan, Shao-Bin Duan, Xiao-Qin Luo, Ning-Ya Zhang, Ying-Hao Deng
Summary: This study investigated the effects of intravenous hydration in preventing post-contrast outcomes in patients with low eGFR undergoing intravenous administration of iodinated contrast media. Through propensity score matching and analysis, it was found that intravenous hydration was not associated with a lower risk of post-contrast acute kidney injury (PC-AKI), chronic dialysis at discharge, and in-hospital mortality.
EUROPEAN RADIOLOGY
(2023)
Review
Medicine, General & Internal
Matthias Klingele, Lea Baerens
Summary: Acute kidney injury is a common complication in critically ill patients with high mortality rates, especially in those requiring dialysis. Different approaches to renal replacement therapy have been attempted, but their impact on reducing mortality remains inconclusive in larger studies. The challenge remains in determining the most effective use of dialysis in critically ill patients.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Medicine, General & Internal
Ashraf O. Oweis, Sameeha A. Alshelleh, Lubna Hawasly, Ghalia Alsabbagh, Karem H. Alzoubi
Summary: This retrospective study focused on the occurrence of acute kidney injury (AKI) in hospitalized COVID-19 patients. The study found that AKI occurred in 25.3% of the patients, with older age, diabetes mellitus, hypertension, ACEI/ARB use, erythrocyte-sedimentation rate, CRP, and ferritin being predictors of AKI. The mortality rate was high among AKI patients, with 75.9% dying in comparison to 24.1% of non-AKI patients. Among COVID-19 patients admitted to the ICU, 80.5% died, with 70.5% from the AKI group and 29.5% from the non-AKI group.
INTERNATIONAL JOURNAL OF GENERAL MEDICINE
(2022)
Article
Medicine, General & Internal
Daniela Ponce, Welder Zamoner, Dayana Bitencourt Dias, Erica Pires da Rocha, Christiane Kojima, Andre Luis Balbi
Summary: This study aimed to investigate the role of peritoneal dialysis (PD) in acute-on-chronic liver disease (ACLD) in terms of metabolic and fluid control and outcomes. Factors such as MELD score, mechanical ventilation, and fluid balance were associated with the occurrence of liver-kidney syndrome, while nephrotoxic acute kidney injury may have a protective effect.
FRONTIERS IN MEDICINE
(2021)
Article
Critical Care Medicine
Fernando G. Zampieri, Bruno R. da Costa, Suvi T. Vaara, Francois Lamontagne, Bram Rochwerg, Alistair D. Nichol, Shay McGuinness, Danny F. McAuley, Marlies Ostermann, Ron Wald, Sean M. Bagshaw
Summary: The reanalysis using Bayesian framework of the STARRT-AKI trial found that an accelerated strategy of kidney-replacement therapy initiation did not offer clinically important benefits compared to a standard strategy. Patients receiving the accelerated strategy may have fewer days alive and free from kidney-replacement therapy.
Article
Medicine, General & Internal
Lukasz Kuzma, Anna Tomaszuk-Kazberuk, Anna Kurasz, Malgorzata Zalewska-Adamiec, Hanna Bachorzewska-Gajewska, Slawomir Dobrzycki, Marlena Kwiatkowska, Jolanta Malyszko
Summary: Patients with atrial fibrillation (AF) scheduled for coronary angiography are at higher risk of post-contrast acute kidney injury (PC-AKI), especially those with chronic kidney disease (CKD). This study found that kidney impairment was twice as common in AF patients undergoing coronary angiography, highlighting the need for extra caution in these cases.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Hematology
Adi Elias, Doron Aronson
Summary: In patients with suspected pulmonary embolism, the use of intravenous contrast material during CTPA did not increase the risk of AKI. The diagnostic superiority of CTPA supports its reassuring use in patients with suspected PE perceived to be at risk for AKI.
THROMBOSIS AND HAEMOSTASIS
(2021)
Article
Medicine, General & Internal
Welder Zamoner, Camilla Andrade da Silva Santos, Luis Eduardo Magalhaes, Paula Gabriela Sousa de Oliveira, Andre Luis Balbi, Daniela Ponce
Summary: This study found that AKI incidence was higher in Brazilian COVID-19 patients, especially in ICU patients, with risk factors including obesity and higher APACHE II scores. Higher mortality rates were observed in elderly patients, those with more severe disease manifestation, and those with KDIGO stage 3 AKI.
FRONTIERS IN MEDICINE
(2021)
Editorial Material
Urology & Nephrology
Wei Chen, Nina Caplin, Osama El Shamy, Shuchita Sharma, Maryanne Y. Sourial, Michael J. Ross, Mina H. Sourial, Kalyan Prudhvi, Ladan Golestaneh, Vesh Srivatana, Rochelle Dalsan, Daniil Shimonov, Luis Sanchez-Russo, Sara Atallah, Jaime Uribarri
Summary: The study demonstrated the feasibility of acute PD for acute kidney injury during the COVID-19 pandemic and identified male sex and mechanical ventilation on admission as significant predictors of mortality.
KIDNEY INTERNATIONAL
(2021)