Review
Nutrition & Dietetics
Christie C. A. Noble, Jonathan P. Sturgeon, Mutsa Bwakura-Dangarembizi, Paul Kelly, Beatrice Amadi, Andrew J. Prendergast
Summary: The study identified that providing pancreatic enzyme supplements can reduce inpatient mortality, prebiotics or synbiotics have a certain effect on reducing mortality, and psychosocial stimulation can lower mortality rates and improve neurodevelopmental scores.
AMERICAN JOURNAL OF CLINICAL NUTRITION
(2021)
Article
Multidisciplinary Sciences
Akash Ranjan Singh, Amber Kumar, Hemant Deepak Shewade, Bhavna Dhingra
Summary: In India, there is a lack of optimal utilization of the opportunity provided by NRCs for screening and managing TB among under-five children with SAM. Challenges include poor team skills, lack of diagnostic facilities, and inadequate understanding of the guidelines.
Article
Multidisciplinary Sciences
Divya Reddy, Yicheng Ma, Subitha Lakshminarayanan, Swaroop Sahu, Laura F. White, Ayiraveetil Reshma, Gautam Roy, Padmini Salgame, Selby Knudsen, Chelsie Cintron, Jerrold J. Ellner, C. Robert Horsburgh, Sonali Sarkar, Natasha S. Hochberg
Summary: Severe undernutrition in children was associated with decreased odds of TST positivity. Caution is warranted when interpreting negative results in undernourished populations, as false-negative TSTs may result from undernutrition.
Article
Immunology
Camino Trobajo-Sanmartin, Ana Miqueleiz, Marcela Guevara, Miguel Fernandez-Huerta, Cristina Burgui, Itziar Casado, Fernando Baigorria, Ana Navascues, Carmen Ezpeleta, Jesus Castilla
Summary: This study compared the risk of COVID-19 outcomes among different co-circulating SARS-CoV-2 variants in Navarra, Spain. The Alpha and Delta variants were associated with a higher risk of hospitalization and severe disease, while the Omicron BA.1 and BA.2 variants showed lower risks.
JOURNAL OF INFECTIOUS DISEASES
(2023)
Article
Nutrition & Dietetics
Masafumi Nozoe, Tatsuro Inoue, Mitsuru Ishida, Kenta Yamamoto, Masashi Kanai
Summary: This study aimed to investigate the effects of malnutrition on trunk function and lower leg muscle strength in acute stroke patients upon hospitalization. Nutritional status, trunk function, and lower leg muscle strength were assessed on admission and at discharge. Logistic regression analysis revealed that malnutrition was independently associated with poor trunk function improvement but not with lower leg muscle strength improvement.
Article
Public, Environmental & Occupational Health
Bulcha Guye Adema, Niguse Tadele Atnafu, Feven Mulugeta Ashagre
Summary: This study aimed to determine the perceived quality of care for severe acute malnutrition (SAM) management among caregivers of under-five children. The study found that urban residence, higher education levels, government employee status, and longer hospital stays were significantly associated factors with perceived low-quality care for SAM management.
FRONTIERS IN PUBLIC HEALTH
(2023)
Review
Nutrition & Dietetics
Jonathan P. Sturgeon, James M. Njunge, Claire D. Bourke, Gerard Bryan Gonzales, Ruairi C. Robertson, Mutsa Bwakura-Dangarembizi, James A. Berkley, Paul Kelly, Andrew J. Prendergast
Summary: Severe acute malnutrition (SAM) is a life-threatening condition that contributes to a significant number of deaths in children under 5 in low-income countries. This review explores the role of inflammation in SAM and suggests potential therapeutic interventions based on evidence from other inflammatory syndromes.
Article
Multidisciplinary Sciences
Laura Medialdea, Barry Bogin, Mbeugue Thiam, Antonio Vargas, Maria D. Marrodan, Nicole I. Dossou
Summary: The study proposed the use of 2D geometric morphometric techniques to analyze the relationship between children's morphological changes and nutritional status, identifying significant factors such as nutritional status, age, and gender. Discriminant functions constructed in the study achieved the best classification rates in the left arm, providing insights into the morphological patterns influenced by nutritional status during the first 5 years of growth and development in children.
SCIENTIFIC REPORTS
(2021)
Article
Multidisciplinary Sciences
Arpeeta Sharma, Judy S. Y. Choi, Anna M. D. Watson, Leila Li, Thomas Sonntag, Man K. S. Lee, Andrew J. Murphy, Miles De Blasio, Geoffrey A. Head, Rebecca H. Ritchie, Judy B. de Haan
Summary: The prevalence of hypertension in diabetic patients is 1.5-2.0 times higher than in non-diabetic patients. This co-existent disease worsens cardiac and vascular damage, causing structural and functional changes to the myocardium, impaired cardiac function and heart failure. Oxidative stress and inflammation contribute to pathological cardiac remodeling in these conditions. A preclinical mouse model combining diabetes and hypertension was developed to investigate the cardiovascular pathology of co-morbid diseases.
SCIENTIFIC REPORTS
(2023)
Article
Nutrition & Dietetics
Tannaz Rajabi, Sam K. Schell, Sophia E. Agapova, Amir Hassan, Max Zalta, Donna R. Wegner, Meghan Callaghan-Gillespie, Aminata Koroma, Mohamed Tabita Kamara, Mark J. Manary, Kevin B. Stephenson
Summary: The study found that supplementary feeding for children with moderate wasting can reduce their risk of progressing to severe acute malnutrition (SAM) or death. It also improves the health of their midupper arm circumference (MUAC), decreases the severity of moderate wasting, and increases their weight and MUAC gains.
JOURNAL OF NUTRITION
(2022)
Article
Nutrition & Dietetics
Pilar Charle-Cuellar, Noemi Lopez-Ejeda, Abdoul Aziz Gado, Abdias Ogobara Dougnon, Atte Sanoussi, Nassirou Ousmane, Ramatoulaye Hamidou Lazoumar, Luis Javier Sanchez-Martinez, Fanta Toure, Antonio Vargas, Saul Guerrero
Summary: This study aims to evaluate the effectiveness and coverage of a simplified protocol for treating severe acute malnutrition in children in the humanitarian context of Diffa. The intervention group, treated with the simplified protocol, had a higher cured proportion (96.6%) compared to the control group (87.4%). Additionally, the intervention group required a lower quantity of therapeutic food during treatment.
Article
Medicine, Research & Experimental
Manish Sagar, Katherine Reifler, Michael Rossi, Nancy S. Miller, Pranay Sinha, Laura F. White, Joseph P. Mizgerd
Summary: The study suggests that individuals with prior endemic coronavirus infections were tested more frequently for respiratory infections, but had similar rates of acquiring SARS-CoV-2. Additionally, patients with previous endemic coronavirus infections experienced less severe cases of COVID-19.
JOURNAL OF CLINICAL INVESTIGATION
(2021)
Article
Nutrition & Dietetics
Imtiaz Hussain, Atif Habib, Shabina Ariff, Gul Nawaz Khan, Arjumand Rizvi, Suhail Channar, Abid Hussain, Shahid Fazal, Deepak Kumar, Jose Luis Alvarez, Saul Guerrero, Angeline Grant, Sajid Bashir Soofi
Summary: The study in a rural district in Sindh, Pakistan found no significant difference in the treatment of severe acute malnutrition (SAM) between lady health workers and the standard CMAM program. Recovery rate, relapse rate, death rate and defaulter rate were all similar between the two groups. Compliance with RUTF was higher in the control group compared to the intervention group. Further trials in different settings are recommended to confirm these results.
EUROPEAN JOURNAL OF NUTRITION
(2021)
Review
Oncology
Yves Ingenbleek
Summary: Transthyretin is a liver-secreted plasma protein that correlates with changes in lean body mass throughout the human lifespan and can be used as a marker for disease burden. Malnutrition and inflammation can inhibit Transthyretin production through different mechanisms and contribute to a reduction in lean body mass reserves.
FRONTIERS OF MEDICINE
(2022)
Article
Public, Environmental & Occupational Health
Rakesh Kumar, Lalit Dar, Ritvik Amarchand, Siddhartha Saha, Kathryn E. Lafond, Debjani R. Purakayastha, Ramesh Kumar, Avinash Choudekar, Giridara Gopal, Shivram Dhakad, Venkatesh Vinayak Narayan, Abhishek Wahi, Reshmi Chhokar, Stephen Lindstrom, Brett Whitaker, Aashish Choudhary, A. B. Dey, Anand Krishnan
Summary: Limited data on acute lower respiratory tract infection (LRTI) among older adults in low- and middle-income countries were investigated over a two-year period. Chronic bronchitis was identified as an important risk factor, with influenza virus and RSV being major viral pathogens in this population. The incidence of LRTI was found to be substantial in older adults, with influenza and RSV being commonly detected.
JOURNAL OF GLOBAL HEALTH
(2021)