Article
Pharmacology & Pharmacy
Ning Li, Hui Zhou, Xiaohui Chen, Hang Chen, Huifen Tang, Yanmei Yao
Summary: The study demonstrates that Paederia foetida significantly inhibits BaP-induced gastric cancer and shows promising anticancer effects.
LATIN AMERICAN JOURNAL OF PHARMACY
(2021)
Article
Genetics & Heredity
Wei Wang, Tao Xu, Xiangwen Song, Cunwu Chen, Dong Liu, Bangxing Han, Shanyong Yi
Summary: In this study, the first complete chloroplast genome sequence of Paederia foetida was assembled and characterized. The genome was 153,591 bp in length with 37.74% GC content and encoded 133 genes. Phylogenetic analysis revealed the close relationship between P. foetida and P. scandens.
MITOCHONDRIAL DNA PART B-RESOURCES
(2022)
Article
Plant Sciences
Rajdeep Sarma, Neha Ghimire, Obaidur Rahman, Lipoksangla Jamir, Sushil Kumar Chaudhary, Siddharth Singh, Hans Raj Bhat, Surajit Kumar Ghosh, Anshul Shakya
Summary: Paederia foetida Linn. has been traditionally used as medicine for various diseases in subtropical countries. Phytochemical investigations revealed the presence of multiple compounds in its leaves. Subchronic oral toxicity study showed no adverse effects of long-term consumption of the hydroalcoholic extract of P. foetida leaves in mice.
SOUTH AFRICAN JOURNAL OF BOTANY
(2022)
Article
Pharmacology & Pharmacy
Mukhriani, Yusnita Rifai, Yulia Yusriani Djabir, Muammar Fawwaz, Gemini Alam
Summary: Paederia foetida L. leaves extract showed strong antioxidant capacity and inhibitory activity on tyrosinase activity, indicating its potential as a functional food ingredient.
INDONESIAN JOURNAL OF PHARMACY
(2023)
Article
Environmental Sciences
Kailun Sun, Meifei Li, Yan Song, Jingchun Tang, Rutao Liu
Summary: The study revealed that earthworm SOD activity was significantly inhibited under 2-Pentanone stress, leading to an increase in lipid peroxidation. CAT and T-AOC were activated to resist oxidative damage. Molecular assays showed that 2-pentanone altered the secondary structure of SOD, affecting its activity.
Review
Pharmacology & Pharmacy
Mrinal Kashyap Sarma, Dipankar Saha, Bhrigu Kumar Das, Trishna Das, Shavkatjon Azizov, Deepak Kumar
Summary: Paederia foetida is a medicinal plant with various pharmacological activities, including anti-diabetic, antioxidant, anti-inflammatory, and hepatoprotective effects. Its active constituents are also found to be effective in cancer, inflammatory diseases, wound healing, and spermatogenesis. These findings highlight the potential of Paederia foetida for further research in medicine.
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY
(2023)
Article
Chemistry, Medicinal
Aryandi Ramadhan, Agustin Krisna Wardani, Bongani Sicelo Dlamini, Chi- Chang
Summary: Paederia foetida, a plant species found in East and South Asia, has been traditionally used in Chinese medicine for treating gastric infections and digestive disorders. This study isolated bioactive compounds from the stem of P. foetida and found that compounds 2 and 3 exhibited significant inhibition against Staphylococcus aureus, showing potential as candidates for treating staphylococcal bacterial infections in both human and animals.
NATURAL PRODUCTS JOURNAL
(2021)
Article
Biology
Tayyiba Afzal, Yamin Bibi, Muhammad Ishaque, Saadia Masood, Abdul Qayyum, Sobia Nisa, Zahid Hussain Shah, Hameed Alsamadany, Gyuhwa Chung
Summary: This research found that the leaves of Pseudocaryopteris foetida are rich in phenolic and flavonoid compounds, showing certain antioxidant activity but weak cytotoxicity. Further research should be focused on isolating bioactive compounds from this plant for potential clinical applications.
SAUDI JOURNAL OF BIOLOGICAL SCIENCES
(2022)
Article
Chemistry, Multidisciplinary
Nguyen Quang Trung, Nguyen Minh Thong, Dao Hung Cuong, Tran Duc Manh, Loc Phuoc Hoang, Nguyen Khoa Hien, Pham Cam Nam, Duong Tuan Quang, Adam Mechler, Quan V. Vo
Summary: Anthraquinones isolated from Paederia plants have various pharmacological activities, including antioxidant and anti-inflammatory properties, with particularly effective superoxide anion scavenging activity in aqueous solution.
Article
Multidisciplinary Sciences
G. Yhoan S. Gaviria, M. Jose E. Zapata
Summary: Earthworms can be used not only to produce organic fertilizer, but also as a rich source of bioactive compounds for pharmaceutical purposes. The enzymatic hydrolysis of Eisenia foetida protein was optimized and scaled up in this study, and the resulting hydrolysates showed high antioxidant activity.
Article
Acoustics
Yuxin Liu, Wang Zhe, Ruifen Zhang, Ziting Peng, Yuxi Wang, Heqi Gao, Zhiqiang Guo, Juan Xiao
Summary: Ultrasonic-assisted extraction coupled with deep eutectic solvent is an efficient and green method for extracting phytochemicals. This study investigated the effects of different deep eutectic solvents on the extraction rate of polyphenols from Paederia scandens. The results showed that the deep eutectic solvent synthesized with choline chloride and ethylene glycol had the highest extractability. The optimal extraction parameters resulted in the highest total flavonoid content and antioxidant power, which were comparable to the experimental results. Furthermore, the deep eutectic solvents coupled with ultrasonic-assisted extraction showed higher extraction efficiency compared to traditional methods.
ULTRASONICS SONOCHEMISTRY
(2022)
Article
Chemistry, Multidisciplinary
Nguyen Quang Trung, Nguyen Thi Thu Thanh, Nguyen Thi Hoa, Adam Mechler, Quan V. Vo
Summary: Paederia scandens is a widely used medicinal herb in Vietnam, China, India, and Japan for various conditions. Two iridoid glucosides obtained from P. scandens (6-FMT and 10-FMT) are potential antioxidants. In non-polar environments, these FMTs are predicted to be weak antioxidants, but they exhibit good HOO scavenging activity in polar environments.
Article
Biochemistry & Molecular Biology
Yanxiang Xu, Jia Zeng, Lin Wang, Jingwen Xu, Xiangjiu He, Yihai Wang
Summary: Twenty known compounds and eight previously undescribed iridoid glycosides were isolated from the aerial parts of Paederia scandens (Lour.) Merrill (Rubiaceae). The structures and absolute configurations of these compounds were determined through comprehensive analyses of NMR data, HR-ESI-MS spectrometry, and ECD data. The potential anti-inflammatory activities of the isolated compounds were evaluated and compound 6 showed significant inhibition of nitric oxide production. It exhibited anti-inflammatory activity by suppressing nuclear translocation of NF -KB and reducing the expression of COX-2, iNOS, IL-1 beta, and IL-6.
Article
Engineering, Multidisciplinary
Nasmi Herlina Sari, Edi Syafri, Suteja, Widya Fatriasari, Azizatul Karimah
Summary: This study investigated the effects of NaOH and KOH treatments on the surface of Paederia foetida fiber (PFs). The results showed that after treatment, the fiber diameter and moisture content decreased, while the tensile strength and thermal stability increased significantly. NaOH treatment was found to be more effective in removing lignin and hemicellulose components and increasing cellulose compounds. The treated fibers have the potential to replace glass fibers and coconut fibers in lightweight composite and construction applications.
JOURNAL OF APPLIED SCIENCE AND ENGINEERING
(2023)
Article
Forestry
Minghao Chen, Mingling Cai, Ping Xiang, Zhangfen Qin, Changlian Peng, Shaoshan Li
Summary: Ipomoea cairica is an invasive vine with strong ecological adaptability, while its invasion mechanism under global warming is still unknown. This study examined the thermal adaptability of I. cairica and its comparison to a native vine P. scandens. The results showed that I. cairica had higher photosynthesis and was more temperature-sensitive. In addition, I. cairica exhibited better thermal adaptation through increased soluble sugar and antioxidant enzyme activity, while P. scandens adopted a thermal-avoidance strategy. The study suggested that increased heat disturbance under global warming will enhance the invasion capability of I. cairica but inhibit P. scandens.