Article
Acoustics
Kaouther Kerboua, Oualid Hamdaoui, Abdulaziz Alghyamah
Summary: This paper reports a numerical investigation on the feasibility of a hybrid concept combining an ionic liquid with sonication for cellulose decomposition. The results show important findings regarding cavitation formation and extreme conditions generated for cellulose decomposition.
ULTRASONICS SONOCHEMISTRY
(2021)
Article
Biochemistry & Molecular Biology
Maanas Sharma, Kshirod K. Dash, Laxmikant S. Badwaik
Summary: The phytochemical-rich extract from black jamun pulp was successfully encapsulated using vibrating dripping extrusion technique with four variations of core-shell materials. Among them, AL-GG based encapsulated jamun extract beads showed better physicochemical characteristics and high encapsulation efficiency. The release kinetics study revealed that AL-GA and AL-GG based beads exhibited the best release behavior in simulated gastrointestinal fluids. Overall, the encapsulated Jamun beads demonstrated excellent agro-industrial efficacy with promising antioxidant potential.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2022)
Article
Food Science & Technology
Manoela Martins, Ana Carla Kawazoe Sato, Kenji Ogino, Rosana Goldbeck
Summary: The study demonstrated that adding up to 3% xylooligosaccharides into alginate-gelatin blend could form a cohesive matrix with smaller pores and crystalline structure, confirming the potential of xylooligosaccharides hydrogels for the development of functional and synbiotic foods.
FOOD RESEARCH INTERNATIONAL
(2021)
Article
Food Science & Technology
Jose Honorio Pereira Lopes Neto, Marilia Cicera Gomes dos Santos, Kerolayne Santos Leite, Liliane Andrade da Silva, Maria Isabel Ferreira Campos, Emmanuel Souza da Silveira, Joao Bosco Sousa Amaral, Marta Suely Madruga, Ana Luiza Mattos Braga, Haissa Roberta Cardarelli
Summary: Probiotic microencapsulation with L-cysteine hydrochloride and/or ascorbic acid was developed and added to Reino cheese for enhanced survival of Lb. acidophilus. The best microparticles formulation showed high lactobacilli viability and protection, resulting in functional probiotic potential for industrial application in ripened Reino cheese.
LWT-FOOD SCIENCE AND TECHNOLOGY
(2021)
Article
Pharmacology & Pharmacy
Hassan Ahmad, Tahir Ali Chohan, Jahanzeb Mudassir, Prina Mehta, Bushra Yousef, Aliyah Zaman, Amna Ali, Omar Qutachi, Ming-Wei Chang, Dimitris Fatouros, Muhammad Sohail Arshad, Zeeshan Ahmad
Summary: This study aimed to develop in-situ gels containing naproxen sodium and sodium alginate. The gel formation was studied in different physiological ions, and the gel formulations were evaluated for physical attributes and drug release. In vivo studies showed the potential of the in-situ gel for sustained release of naproxen sodium and treatment of chronic inflammatory conditions.
INTERNATIONAL JOURNAL OF PHARMACEUTICS
(2022)
Article
Chemistry, Physical
Jilin Fan, Mingjun Xuan, Pengkun Zhao, Mark Loznik, Junlin Chen, Fabian Kiessling, Lifei Zheng, Andreas Herrmann
Summary: The development of ultrasound-responsive microcapsule structures has provided new insights into the development of ultrasound triggered small molecule drug delivery assisted by metallic nanoparticles. By employing nanodrugs encapsulated in microcapsules, drug leakage can be prevented and the delivery system can respond to high-intensity focused ultrasound.
Article
Chemistry, Physical
Jilin Fan, Mingjun Xuan, Pengkun Zhao, Mark Loznik, Junlin Chen, Fabian Kiessling, Lifei Zheng, Andreas Herrmann
Summary: The development of ultrasound-responsive microcapsule structures has enabled the controlled delivery of macromolecular cargoes for biomedical applications. However, delivering small molecular cargoes using microcapsules has been a challenge due to drug leakage. In this study, we proposed a new strategy by using nanodrugs encapsulated in microcapsules, which prevented drug leakage and provided responsiveness to ultrasound. Furthermore, we demonstrated the activation of antibacterial activity by ultrasound using the nanodrug@Microcapsules.
Article
Acoustics
Rassoul Mozafarpour, Arash Koocheki
Summary: Emulsion gels were prepared using sonicated grass pea protein isolates (GPPI) at different ultrasonic amplitudes and times. Enzymatic gelation occurred in two stages, leading to the formation of a stronger gel structure. The emulsion gels fabricated by sonicated GPPI showed higher elastic modulus, water holding capacity, and thermal stability compared to native GPPI gels. The microstructures of the sonicated-GPPI emulsion gels were nearly identical for all sonication conditions.
ULTRASONICS SONOCHEMISTRY
(2023)
Article
Food Science & Technology
Mariana Pereira Silveira, Francisco Lucas Chaves Almeida, Izabela Dutra Alvim, Ana Silvia Prata
Summary: This study aimed to produce pectin hydrogel beads for carrying pomegranate extract (PE) and evaluate various strategies to increase its retention and protect the polyphenols. The results showed that equalizing the concentration of the external medium with the beads formulation significantly improved encapsulation efficiency. Increasing PE concentration was proportional to the rise in the mechanical strength of the beads. Adsorption was efficient in entrapping the active compound, while coating could reduce the release rate but needs improvement.
FOOD RESEARCH INTERNATIONAL
(2023)
Article
Polymer Science
Asmaa M. Elzayat, Ines Adam-Cervera, Marie Albus, Amparo Chafer, Jose D. Badia, Francisco F. Perez-Pla, Rafael Munoz-Espi
Summary: Polysaccharide/silica hybrid microcapsules were prepared using ionic gelation followed by spray-drying. The presence of silica affected the morphology and stability of the particles, and showed excellent performance as catalysts for organic reactions.
Article
Chemistry, Multidisciplinary
Yi-Ju Ho, Ho-Chun Chang, Chia-Wei Lin, Ching-Hsiang Fan, Yu-Chun Lin, Kuo-Chen Wei, Chih-Kuang Yeh
Summary: Drug-loaded microbubbles combined with ultrasound excitation for targeted drug release have shown to improve drug delivery efficiency by modulating targeted microbubble oscillation. Stable cavitation enhances cell permeability and cell viability, leading to increased in vivo vesicle release on tumor vessels. This strategy may have potential applications in tissue repair or neuromodulation.
JOURNAL OF CONTROLLED RELEASE
(2021)
Article
Engineering, Chemical
I. D. Perez-Landa, I. Bonilla-Landa, J. L. Monribot-Villanueva, M. Ramirez-Vazquez, R. Lasa, W. Ramos-Torres, J. L. Olivares-Romero, F. Barrera-Mendez
Summary: This study developed a photoprotective system for intake administration using chitosan and sodium lignosulfonate as encapsulating materials for the photosensitive spinosad. In vitro release studies showed high stability to photodegradation and appropriate insecticide release rate for the developed bioinsecticide carrier system.
Article
Biochemistry & Molecular Biology
Aleena Mir, Amit Kumar, Javed Alam, Ufana Riaz
Summary: Composite hydrogels with conducting polymers were synthesized and studied for drug release. The release kinetics showed prolonged and sustained release at different pH values.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Food Science & Technology
Martina Vakarelova, Francesca Zanoni, Giulia Dona, Ilaria Fierri, Roberto Chignola, Sara Gorrieri, Gianni Zoccatelli
Summary: This study aimed to microencapsulate astaxanthin (ASX) using ionic gelation with low-methoxyl pectin (LMP), chitosan, and alginate. The results showed that adding chitosan improved particle sphericity and limited oil oxidation. The combination of LMP and chitosan achieved the highest encapsulation efficiency and bioaccessibility.
INTERNATIONAL JOURNAL OF FOOD SCIENCE AND TECHNOLOGY
(2023)
Article
Chemistry, Multidisciplinary
Luc Zongo, Heiko Lange, Claudia Crestini
Summary: Microcapsules of sulfited Acacia mearnsii tannin (AmST-MCs) were generated for the first time using sonochemical method. The study found excellent stability of TMCs over time and under high temperature and pressure conditions, with active release triggered by varying pH and salinity. Surfactants and salt components in solutions also significantly affected the stability of TMCs.
Article
Pharmacology & Pharmacy
A. J. Rajamma, S. B. Sateesha, M. K. Narode, V. R. S. S. Prashanth, A. M. Karthik
INDIAN JOURNAL OF PHARMACEUTICAL SCIENCES
(2015)
Article
Chemistry, Applied
A. J. Rajamma, Sonal Dubey, S. B. Sateesha, S. N. Tiwari, S. K. Ghosh
NATURAL PRODUCT RESEARCH
(2011)
Article
Pharmacology & Pharmacy
A. J. Rajamma, H. N. Yogesha, S. B. Sateesha
DARU-JOURNAL OF PHARMACEUTICAL SCIENCES
(2012)
Article
Chemistry, Medicinal
Sateesha S. Boregowda, Karnati Nithinkumar, Rajamma A. Jayaramu, Chandan Kalegowda, Govindareddy Y. Avalakondareddy
Summary: The study demonstrated the efficacy of a polyherbal formulation in treating ulcerative colitis following sub-chronic administration, with results showing that the polyherbal formulation is as effective as mesalamine in treating ulcerative colitis.
NATURAL PRODUCTS JOURNAL
(2021)
Article
Chemistry, Multidisciplinary
Syed M. D. Rizvi, Manjunatha P. Mudagal, Sateesha S. Boregowda, Talib Hussain, Turki Al Hagbani, Marwa H. Abdallah, El-Sayed Khafagy, Arshad Hussain, Fahad A. Yousif Adam, Amr S. Lila
Summary: Hesperidin methyl chalcone (HMC), derived from citrus fruits, has been reported to possess analgesic, anti-inflammatory, and antioxidant properties. This study aimed to evaluate the anticancer potential of HMC. In vitro cytotoxicity assessments showed that HMC efficiently suppressed the viability of A549 cancer cells with an IC50 value comparable to the anticancer agent hesperetin. Moreover, in an Ehrlich ascites carcinoma model, HMC significantly inhibited tumor growth and prolonged the lifespan of treated mice. HMC also exhibited a good safety profile by restoring hematological parameters and reducing oxidative stress. These findings suggest that HMC has promising potential as an anticancer candidate.
ARABIAN JOURNAL OF CHEMISTRY
(2023)
Article
Polymer Science
Poornima K. K. Gopalakrishna, Rajamma Abburu Jayaramu, Sateesha Shivally Boregowda, Shruthi Eshwar, Nikhil V. V. Suresh, Amr Selim Abu Lila, Afrasim Moin, Hadil Faris Alotaibi, Ahmad J. Obaidullah, El-Sayed Khafagy
Summary: This study aimed to develop an in situ gel containing piperine for the treatment of gingivitis and periodontal diseases. Through evaluation and optimization, the gel formulation exhibited good gelation temperature and time, and demonstrated effectiveness in anti-inflammatory activity and drug release in both in vitro and in vivo experiments.
Article
Polymer Science
Shruthi Eshwar, Kranti Konuganti, Supriya Manvi, Aarya N. Bharadwaj, Sudarshan Sajjan, Sateesha Shivally Boregowda, Vipin Jain
Summary: Periodontal diseases affect about half of the global population and their treatment often involves relieving symptoms and regenerating destroyed tissues. This study focused on the development of an injectable fucoidan-chitosan hydrogel for periodontal bone regeneration. The hydrogel showed good biocompatibility, biodegradability, and slow drug release, promoting cell proliferation and bone mineralization. In clinical trials, it demonstrated superior results in terms of reduced probing depths and improved clinical attachment levels compared to concentrated growth factor, indicating its potential for bone tissue regeneration.
Article
Plant Sciences
P. Prashanthi, A. J. Rajamma, S. B. Sateesha, K. Chandan, S. N. Tiwari, S. K. Ghosh
INDIAN JOURNAL OF NATURAL PRODUCTS AND RESOURCES
(2016)
Article
Pharmacology & Pharmacy
Rajamma Abburu Jayaramu, Sateesha Shivally Boregowda, Addanki Rahul Deva Varma, Chandan Kalegowda
BRAZILIAN JOURNAL OF PHARMACEUTICAL SCIENCES
(2014)
Article
Pharmacology & Pharmacy
S. B. Sateesha, A. J. Rajamma, H. S. Shekar, G. Divakar
DARU-JOURNAL OF PHARMACEUTICAL SCIENCES
(2011)