Article
Chemistry, Physical
Natalia Przybylska, Malgorzata Sliwinska-Bartkowiak, Mikolaj Koscinski, Konrad Rotnicki, Marek Bartkowiak, Stefan Jurga
Summary: This study investigated the properties of water solution of ciprofloxacin confined in single wall carbon nanotubes, examining the influence of nanotube size and structure on interactions with the drug. Raman spectroscopy of the carbon nanotubes revealed a correlation between their amorphousness and semiconductor properties, while FT-IR spectroscopy was used to identify the structure of the confined ciprofloxacin and determine which vibrations of functional groups in the ciprofloxacin molecule were suppressed by confinement.
JOURNAL OF MOLECULAR LIQUIDS
(2021)
Article
Chemistry, Analytical
P. R. Ipte, Abhishek Sharma, H. Pal, A. K. Satpati
Summary: The study revealed a good interaction between Cf and dsDNA, forming a stable complex in solution through electrostatic interaction and intercalative binding. The presence of Cf led to the condensation of dsDNA, facilitated by electrostatic interaction and specific functional group interactions.
JOURNAL OF ELECTROANALYTICAL CHEMISTRY
(2021)
Article
Environmental Sciences
Emilia Uurasjarvi, Erika Sainio, Outi Setala, Maiju Lehtiniemi, Arto Koistinen
Summary: This study investigated the ingestion of microplastics by wild freshwater fish species. Results show that a small percentage of perch and vendace had ingested plastic, with most microplastics found being polyethylene, polypropylene, and polyethylene terephthalate. The developed method revealed low levels of ingested microplastics on average, suggesting the need for further development for routine monitoring of small microplastics.
ENVIRONMENTAL POLLUTION
(2021)
Article
Biochemistry & Molecular Biology
Tatiana Tozar, Mihai Boni, Angela Staicu, Mihail Lucian Pascu
Summary: This study demonstrates the efficient photodegradation of ciprofloxacin using 266 nm laser beams, with analysis conducted through UV-Vis and FTIR spectroscopy, pH assay, and laser-induced fluorescence. HPTLC densitometry was utilized for characterizing fluorescence and fluorescence lifetime of photodegradation products. The results provide valuable insights into the degradation process and the identification of photoproducts.
Article
Biochemical Research Methods
Kieran Elmes, Astra Heywood, Zhiyi Huang, Alex Gavryushkin
Summary: Large-scale genotype-phenotype screens provide valuable data for identifying molecular alterations associated with a phenotype. This study focuses on the importance of epistatic effects in association studies, and aims to develop a method that can consider three-way interactions. The proposed method, Pint, outperforms known methods in simulated data and demonstrates accuracy in antibiotic resistance testing and siRNA perturbation screens.
PLOS COMPUTATIONAL BIOLOGY
(2022)
Article
Chemistry, Physical
Aline R. Doria, Isabelle M. D. Gonzaga, Gessica O. S. Santos, Caio V. S. Almeida, Deyvid C. Silva, Ronaldo S. Silva, Luciane P. C. Roma, Cristina Saez, Giancarlo R. Salazar-Banda, Katlin I. B. Eguiluz
Summary: Ti/RuO2-TiO2 anodes were prepared using unconventional heating methods involving CO2 laser and microwave irradiation. These anodes exhibited improved electrochemical properties compared to conventionally-prepared anodes, with increased voltammetric charge and decreased charge transfer resistance. The laser and microwave-prepared anodes also had longer lifetimes and high efficiency in generating hypochlorite and degrading ciprofloxacin.
APPLIED CATALYSIS B-ENVIRONMENTAL
(2023)
Article
Microbiology
France Emilie Roy, Tammy Berteau, Julie Bestman-Smith, Simon Grandjean Lapierre, Simon Frederic Dufresne, Marc-Christian Domingo, Jean-Michel Leduc
Summary: Aerococcus urinae is a urinary pathogen known for its resistance to fluoroquinolones. This study validated the Etest method on sheep blood agar for testing the susceptibilities of Aerococcus urinae to ciprofloxacin and levofloxacin, comparing it with the BMD method. The study found good agreement between Etest results and the reference methods, making it a suitable option for clinical laboratories testing Aerococcus urinae isolates.
JOURNAL OF CLINICAL MICROBIOLOGY
(2021)
Article
Pharmacology & Pharmacy
Muhammad Talha Usmani, Muhammad Harris Shoaib, Fahad Siddiqui, Farrukh Rafiq Ahmed, Sabahat Jabeen, Rehana Saeed, Kamran Ahmed, Sadaf Farooqi, Tazeen Hussain, Syed Muhammad Imran
Summary: A new liquid chromatographic method was developed for the analysis of Ciprofloxacin in human plasma, which is simple, accurate, precise, and sensitive. The method was validated using HPLC-UV and successfully applied to pharmacokinetic studies of Ciprofloxacin.
PAKISTAN JOURNAL OF PHARMACEUTICAL SCIENCES
(2021)
Article
Biochemistry & Molecular Biology
Karishma Singh, Roger M. Coopoosamy, Njabulo J. Gumede, Saheed Sabiu
Summary: This study evaluated the affinity and antibacterial activity of phenolic acid compounds derived from the shikimate pathway against NorA. It found that p-coumaric acid showed the strongest affinity and inhibitory effect. These findings suggest the potential of p-coumaric acid as a novel NorA efflux pump inhibitor.
Article
Thermodynamics
Muchenedi Hari Kishor, M. L. N. Madhu Mohan
Summary: This study investigated the thermal properties of ferroelectric liquid crystalline binary mesogens created by mixing different precursors, confirming the existence of various phases through optical and thermal analysis. By altering the molar ratios of different acids and esters, the relationship between phase behavior and ratio changes was explored.
JOURNAL OF THERMAL ANALYSIS AND CALORIMETRY
(2022)
Article
Biochemistry & Molecular Biology
Dorota Kowalczuk, Agata Gladysz, Monika Pitucha, Daniel M. Kaminski, Agnieszka Baranska, Bartlomiej Drop
Summary: The study investigated the structure of a proposed non-absorbable ciprofloxacin-biguanide bismuth complex as a potential alternative to conventional therapy. Spectroscopic techniques were utilized to characterize the compound's structure, confirming the presence of the active components and revealing the coordination sites of ligands with the bismuth ion.
Article
Meteorology & Atmospheric Sciences
Olivier Bock, Pierre Bosser, Carl Mears
Summary: This paper investigates the measurement and calibration of integrated water vapour (IWV), and highlights the limitations of the widely used correction model. It proposes an improved correction method that incorporates a multiple linear regression approach and validates its effectiveness through experiments. The paper emphasizes the importance of accounting for errors in both variables when using regression methods.
ATMOSPHERIC MEASUREMENT TECHNIQUES
(2022)
Editorial Material
Cardiac & Cardiovascular Systems
Marco Schiavon, Andrea Lloret Madrid, Federica Pezzuto, Chiara Giraudo, Giovanni Maria Comacchio, Eleonora Faccioli, Andrea Dell'Amore, Fiorella Calabrese, Federico Rea
Summary: This article presents a case of spontaneous regression of thoracic malignancy in a patient with epidermal growth factor receptor-mutant adenocarcinoma. The patient experienced contralateral aspiration pneumonia before surgery, but showed complete pathologic regression without any preoperative oncologic treatment. Immune system activation and the role of tumor microenvironment in disease progression and treatment are highlighted.
ANNALS OF THORACIC SURGERY
(2022)
Article
Chemistry, Multidisciplinary
Yanling Li, Ying Wang, Junqing Wu, Yingying Pan, Huangqing Ye, Xiping Zeng
Summary: Silver nanowires (AgNWs) were successfully synthesized using a PVP-free hydrothermal method with Alpinia zerumbet leaf as a reducing agent and template. The diameter and length of AgNWs were approximately 77 nm and 10 μm, respectively. The biomass initially acted as a reducing agent and formed a pipe-shaped soft template during the hydrothermal process. Silver ions were adsorbed and reduced along the soft templates, resulting in the formation of AgNWs through the oriented attachment mechanism. The study also investigated the mechanism of AgNWs synthesized by the polyol method, suggesting that they may also grow based on the oriented attachment mechanism using PVP as a template.
Review
Multidisciplinary Sciences
Johannes Tintner
Summary: Dating of organic findings is a fundamental task in many scientific fields, with radiocarbon dating and dendrochronology being the most commonly used methods. However, both methods have systematic restrictions. Molecular changes over time are reported for many materials under different preservation conditions, serving as clocks that start at the time when a given molecule was formed.
ANNALS OF THE NEW YORK ACADEMY OF SCIENCES
(2021)
Review
Education, Scientific Disciplines
Gaurav Tiwari, Ruchi Tiwari, Pranay Wal
INDIAN JOURNAL OF PHARMACEUTICAL EDUCATION AND RESEARCH
(2019)
Review
Chemistry, Medicinal
Abhinav Prasoon Mishra, Ankit Bajpai, Awani Kumar Rai
MINI-REVIEWS IN MEDICINAL CHEMISTRY
(2019)
Article
Dermatology
Richa Shukla, Gaurav Tiwari, Ruchi Tiwari, Awani K. Rai
JOURNAL OF COSMETIC DERMATOLOGY
(2020)
Review
Pharmacology & Pharmacy
Nandini Chaudhary, Devika Tripathi, Awani K. Rai
CURRENT DRUG DELIVERY
(2020)
Review
Chemistry, Medicinal
Ruchi Tiwari, Gaurav Tiwari, Akanksha Lahiri, Vadivelan Ramachandran, Awani Rai
Summary: This review article summarizes the therapeutic applications, mechanism of action, and recent research progress of melittin (MEL), a component of bee venom. It is found that MEL exerts multiple effects on the cellular functions of infected cells.
NATURAL PRODUCTS JOURNAL
(2022)
Review
Endocrinology & Metabolism
Ruchi Tiwari, Pranay Wal, Priya Singh, Gaurav Tiwari, Awani Rai
Summary: The review article discusses the pathogenesis of Diabetic Peripheral Neuropathy, highlighting metabolic pathways, oxidative stress, and NF-κB activation. Various treatment options, such as acupressure, lidocaine, and capsaicin, are suggested to combat the condition.
CURRENT DIABETES REVIEWS
(2021)
Article
Pharmacology & Pharmacy
Ruchi Tiwari, Gaurav Tiwari, Rachna Singh
CURRENT DRUG THERAPY
(2020)
Article
Materials Science, Biomaterials
Swatantra K. S. Kushwaha, Awani Kumar Rai
Article
Pharmacology & Pharmacy
Ruchi Tiwari, Gaurav Tiwari, Ankita Wal, Chitranshu Gupta
Article
Pharmacology & Pharmacy
Swatantra Kumar Singh Kushwaha, Awani Kumar Rai, Heena Parveen
CURRENT DRUG THERAPY
(2019)
Review
Pharmacology & Pharmacy
Ruchi Tiwari, Gaurav Tiwari, Akanksha Lahiri, R. Vadivelan, Awani K. Rai
Summary: Topical drug delivery has various benefits, while nanofibers are highly efficient in burn care, accelerating wound healing and possessing properties like mechanical integrity and temperature regulation.
ADVANCED PHARMACEUTICAL BULLETIN
(2021)
Review
Veterinary Sciences
Ruchi Tiwari, Kuldeep Dhama, Khan Sharun, Mohd. Iqbal Yatoo, Yashpal Singh Malik, Rajendra Singh, Izabela Michalak, Ranjit Sah, D. Katterine Bonilla-Aldana, Alfonso J. Rodriguez-Morales
VETERINARY QUARTERLY
(2020)
