Article
Nutrition & Dietetics
Xiaotong Wang, Jiajia Jing, Saijun Huang, Xiaoying He, Pingming Gao, Hailin Li, Zongyu Lin, Per Torp Sangild, Yanna Zhu
Summary: Early anemia in very-low-birth-weight (VLBW) preterm infants is negatively correlated with neurodevelopment, especially with behavioral ability, but is not associated with brain injury.
Article
Nutrition & Dietetics
Melanie Gsoellpointner, Margarita Thanhaeuser, Fabian Eibensteiner, Robin Ristl, Bernd Jilma, Renate Fuiko, Sophia Brandstetter, Angelika Berger, Nadja Haiden
Summary: This study analyzed the intake of polyunsaturated fatty acids (PUFAs) during complementary feeding (CF) in very low birth weight (VLBW) infants and its impact on neurodevelopment. The results showed that higher intake of total PUFAs, docosahexaenoic acid (DHA), and arachidonic acid (AA) was associated with improved cognitive and motor function at 12 months of age. However, the dietary intake of AA and DHA did not meet the recommended levels, highlighting the need to increase PUFA, DHA, and AA intake during CF for better neurodevelopmental outcomes in VLBW infants.
Article
Nutrition & Dietetics
Rasa Brinkis, Kerstin Albertsson-Wikland, Rasa Tameliene, Ilona Aldakauskiene, Inesa Rimdeikiene, Vitalija Marmiene, Kastytis Smigelskas, Rasa Verkauskiene
Summary: This study aims to assess the relationship between early nutritional intake, growth in the first year, and neurodevelopment in very low birth weight infants. The results showed slower growth in extremely preterm infants compared to very/moderately preterm infants before discharge, but no differences in anthropometric characteristics or neurodevelopmental scores at 12 months. Higher carbohydrate intake during the first 28 days was a significant predictor for better cognitive scores only in extremely preterm infants.
Article
Pediatrics
Estefania Ruiz-Gonzalez, Simon P. Lubian-Lopez, Natalia Jimenez Luque, Antonio Segado-Arenas, Manuel Lubian-Gutierrez, Yolanda Marin Almagro, Pamela Zafra-Rodriguez, Paula Mendez-Abad, Isabel Benavente-Fernandez
Summary: The study aims to examine the impact of early brain growth in very low birth weight infants on neurological prognosis at 2 years using sequential ultrasound scans. The results show that VLBWI with adverse cognitive prognosis had slower total brain volume growth compared to those with good cognitive prognosis. It was also found that brain volume variation had a greater impact on language prognosis than on cognitive prognosis.
EUROPEAN JOURNAL OF PEDIATRICS
(2023)
Article
Pediatrics
Fiona Barnes, Lynda Graham, Prakash Loganathan, Vrinda Nair
Summary: The study findings suggest that absence of fidgety movements at 3 months post term could be a valuable screening tool for predicting neurodevelopmental outcomes in very low birth weight infants, particularly regarding motor, cognition, language domains, and the risk of cerebral palsy.
INDIAN JOURNAL OF PEDIATRICS
(2021)
Article
Multidisciplinary Sciences
Matthias W. Wagner, Delvin So, Ting Guo, Lauren Erdman, Min Sheng, S. Ufkes, Ruth E. Grunau, Anne Synnes, Helen M. Branson, Vann Chau, Manohar M. Shroff, Birgit B. Ertl-Wagner, Steven P. Miller
Summary: This study aims to predict adverse neurodevelopmental outcomes in very preterm neonates. By using brain MRI and extracting radiomic features, it was found that radiomic features outperformed clinical variables in predicting motor outcomes, and combining the two improved predictive performance.
SCIENTIFIC REPORTS
(2022)
Article
Multidisciplinary Sciences
Qinchuan Shi, Jingjing Zhang, Chong Fan, Aixia Zhang, Zhu Zhu, Yingying Tian
Summary: This study systematically evaluated the risk factors of hypothermia in very low/extremely low birth weight infants. Factors including body weight, failure to keep warm in time, neonatal resuscitation, gestational age, premature rupture of membranes, maternal combined complications, cesarean section, antenatal steroids, multiple birth, small for gestational age, 1 min Apgar score, and 5 min Apgar score were identified. These findings provide a theoretical basis for the prevention and intervention of hypothermia in VLBW/ELBW infants.
Article
Medicine, General & Internal
Liang-Kai Wang, Chen -Yu Chen, Fang-Ju Sun, Chie-Pein Chen
Summary: The study aims to identify perinatal antecedents associated with neurodevelopmental impairment in very low birth weight preterm infants and evaluate the stability of neurodevelopmental assessments at different ages. The findings suggest that multiple perinatal risk factors are associated with poor neurodevelopmental scores in preterm infants, and the predictive ability of assessments at 6 months is limited for outcomes at 24 months.
JOURNAL OF THE FORMOSAN MEDICAL ASSOCIATION
(2022)
Article
Medicine, General & Internal
Charlotte Greer, Sarah L. Harris, Richard Troughton, Philip D. Adamson, John Horwood, Chris Frampton, Brian A. Darlow
Summary: Being born preterm and at very low birth weight is associated with increased cardiopulmonary disorders in childhood and potential late cardiac effects, including right ventricular remodeling and occult pulmonary hypertension as survivors age. In a population-based study, young adults born PT at VLBW exhibited smaller RV dimensions compared to normal-weight term-born controls, with slightly reduced RV function detected using strain imaging. Birth weight and gestational age were related to these differences, highlighting the potential importance of echocardiographic strain imaging in detecting RV function disparities in this population.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Clinical Neurology
Alexander Humberg, Mark Dzietko, Soeren Schulz, Ursula Felderhoff-Mueser, Britta Huening, Anja Stein, Mats Fortmann, Janina Marissen, Tanja K. Rausch, Egbert Herting, Christoph Haertel, Wolfgang Goepel
Summary: Carriers of the APOE-epsilon 4 genotype have an increased risk of long-term motor deficits after intracerebral hemorrhage (ICH) in preterm infants.
Article
Nutrition & Dietetics
Jingxiong Xu, Jean Shin, Meghan McGee, Sharon Unger, Nicole Bando, Julie Sato, Marlee Vandewouw, Yash Patel, Helen M. Branson, Tomas Paus, Zdenka Pausova, Deborah L. O'Connor
Summary: This study found an association between early mother's milk intake by VLBW infants and variations in DNAm as well as neurodevelopmental phenotypes. These findings suggest that early nutrition may have a potential impact on infant's neurodevelopment.
AMERICAN JOURNAL OF CLINICAL NUTRITION
(2022)
Article
Pediatrics
Tzu-Yu Liu, Jui-Hsing Chang, Chun-Chih Peng, Chyong-Hsin Hsu, Wai-Tim Jim, Jia-Ying Lin, Chia-Huei Chen, Sung-Tse Li, Hung-Yang Chang, Taiwan Premature Infant Follow-up Network
Summary: The study assessed the predictive validity of the Bayley Scales of Infant and Toddler Development in very-low-birth-weight infants and identified abnormal muscle tone and lower maternal socioeconomic status as factors associated with changes in cognitive outcomes.
FRONTIERS IN PEDIATRICS
(2021)
Article
Physiology
Ying Qi, Jingni He
Summary: LBW-VLBW neonates show significantly lower CMRO2 and greater physiological deficits compared to term controls. Physiological parameters are valuable for distinguishing different subsets of LBW-VLBW newborns.
FRONTIERS IN PHYSIOLOGY
(2021)
Review
Pediatrics
Shuqiang Gao, Xiaolong Zhang, Weina Du, Xiaofeng Zhou, Yufeng Xi, Rong Ju
Summary: Steroid intervention in very low birth weight preterm infants with bronchopulmonary dysplasia has a significant effect on cognition, but does not show significant effects on hearing, vision, or language function.
TRANSLATIONAL PEDIATRICS
(2021)
Article
Pediatrics
Antti Koivusalo, Janne S. Suominen, Mikko P. Pakarinen
Summary: This study assessed the clinical data and outcome of patients with oesophageal atresia (OA) with very low birth weight (VLBW). The results showed that VLBW patients had similar types of OA as other patients, but had higher incidence of congenital heart disease and chromosomal abnormalities, and lower survival rate. However, in recent years, the survival rate and rate of oesophageal repair have significantly improved.
JOURNAL OF PEDIATRIC SURGERY
(2022)