Journal
INDIAN JOURNAL OF MEDICAL MICROBIOLOGY
Volume 31, Issue 1, Pages 60-63Publisher
ELSEVIER
DOI: 10.4103/0255-0857.108724
Keywords
Acinetobacter baumannii; carbapenemases; nosocomial pathogen; metallo-beta-lactamase; multidrug-resistant Acinetobacter
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Multidrug-resistant (MDR) Acinetobacter baumannii is a worldwide concern as cause of serious nosocomial infections. We analysed 140 non-duplicate Acinetobacter sp. isolates from hospitalised patients in a tertiary care centre; 87% were MDR and 20% (28/140) meropenem resistant. Metallo-beta-lactamase was produced by 16 of these, detected by ethylene-diamine-tetra-acetic acid disc synergy test. AmpC beta-lactamase and efflux pump were present in 17 and 4 of the meropenem-resistant Acinetobacter, respectively. 9/16 MBL-positive isolates carried genes for carbapenem resistance as shown by polymerase chain reaction.
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