Antibody-targeted nanoparticles for cancer therapy

Gene delivery using dimethyldidodecylammonium bromide-coated PLGA nanoparticles

(2010) François Fay et al.   BIOMATERIALS

Affibody-based nanoprobes for HER2-expressing cell and tumor imaging

(2010) Jinhao Gao et al.   BIOMATERIALS

Co-encapsulation of anti-BCR-ABL siRNA and imatinib mesylate in transferrin receptor-targeted sterically stabilized liposomes for chronic myeloid leukemia treatment

(2010) Liliana S. Mendonça et al.   BIOTECHNOLOGY AND BIOENGINEERING

Evaluation of HER2/neu oncoprotein in serum and tissue samples of women with breast cancer: Correlation with clinicopathological parameters

(2010) Mehdi Farzadnia et al.   BREAST

Delivery of PAR-4 plasmid in vivo via nanoliposomes sensitizes colon tumor cells subcutaneously implanted into nude mice to 5-FU

(2010) Christina Leah Kline et al.   CANCER BIOLOGY & THERAPY

Intratumoral Therapy of Glioblastoma Multiforme Using Genetically Engineered Transferrin for Drug Delivery

(2010) Dennis J. Yoon et al.   CANCER RESEARCH

Low Level Her2 Overexpression Is Associated with Rapid Tumor Cell Proliferation and Poor Prognosis in Prostate Cancer

(2010) S. Minner et al.   CLINICAL CANCER RESEARCH

Phase I and Pharmacokinetic Studies of CYT-6091, a Novel PEGylated Colloidal Gold-rhTNF Nanomedicine

(2010) S. K. Libutti et al.   CLINICAL CANCER RESEARCH

Photothermal multispectral image cytometry for quantitative histology of nanoparticles and micrometastasis in intact, stained and selectively burned tissues

(2010) Dmitry A. Nedosekin et al.   CYTOMETRY PART A

In vivo delivery of small interfering RNA to tumors and their vasculature by novel dendritic nanocarriers

(2010) Paula Ofek et al.   FASEB JOURNAL

Radiation-Related Heart Disease: Current Knowledge and Future Prospects

(2010) Sarah C. Darby et al.   INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

Multifunctional Nanoparticles Delivering Small Interfering RNA and Doxorubicin Overcome Drug Resistance in Cancer

(2010) Yunching Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Functionalization of poly(amidoamine) dendrimers with hydrophobic chains for improved gene delivery in mesenchymal stem cells

(2010) José L. Santos et al.   JOURNAL OF CONTROLLED RELEASE

Targeted PLGA nano- but not microparticles specifically deliver antigen to human dendritic cells via DC-SIGN in vitro

(2010) Luis J. Cruz et al.   JOURNAL OF CONTROLLED RELEASE

Benefit of anti-HER2-coated paclitaxel-loaded immuno-nanoparticles in the treatment of disseminated ovarian cancer: Therapeutic efficacy and biodistribution in mice

(2010) A. Cirstoiu-Hapca et al.   JOURNAL OF CONTROLLED RELEASE

The Complex Role of Multivalency in Nanoparticles Targeting the Transferrin Receptor for Cancer Therapies

(2010) Jin Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Management of small HER2-positive breast cancers

(2010) Susana Banerjee et al.   LANCET ONCOLOGY

Single-wall carbon nanotubes assisted photothermal cancer therapy: Animal study with a murine model of squamous cell carcinoma

(2010) Naiyan Huang et al.   LASERS IN SURGERY AND MEDICINE

Ultrahigh Sensitivity Carbon Nanotube Agents for Photoacoustic Molecular Imaging in Living Mice

(2010) Adam de la Zerda et al.   NANO LETTERS

New metal-based nanoparticles for intravenous use: requirements for clinical success with focus on medical imaging

(2010) Tore Skotland et al.   Nanomedicine-Nanotechnology Biology and Medicine

Dendrosome-based delivery of siRNA against E6 and E7 oncogenes in cervical cancer

(2010) Tathagata Dutta et al.   Nanomedicine-Nanotechnology Biology and Medicine

Antibacterial action of dispersed single-walled carbon nanotubes on Escherichia coli and Bacillus subtilis investigated by atomic force microscopy

(2010) Shaobin Liu et al.   Nanoscale

Evidence of RNAi in humans from systemically administered siRNA via targeted nanoparticles

(2010) Mark E. Davis et al.   NATURE

Silencing of the MYCN gene by siRNA delivered by folate receptor-targeted liposomes in LA-N-5 cells

(2010) Chen Feng et al.   PEDIATRIC SURGERY INTERNATIONAL

High level PSMA expression is associated with early psa recurrence in surgically treated prostate cancer

(2010) Sarah Minner et al.   PROSTATE

Pancreatic carcinoma cells are susceptible to noninvasive radio frequency fields after treatment with targeted gold nanoparticles

(2010) Evan S. Glazer et al.   SURGERY

IRX-2 increases the T cell-specific immune response to protein/peptide vaccines

(2010) Paul H. Naylor et al.   VACCINE

Nanotubes in biosensing

(2010) Jianping Lei et al.   Wiley Interdisciplinary Reviews-Nanomedicine and Nanobiotechnology

Effects of nanomaterial physicochemical properties on in vivo toxicity

(2009) Kristin L. Aillon et al.   ADVANCED DRUG DELIVERY REVIEWS

Consensus conference on the use of 90-yttrium-ibritumomab tiuxetan therapy in clinical practice. A project of the Italian Society of Hematology

(2009) Umberto Vitolo et al.   AMERICAN JOURNAL OF HEMATOLOGY

Thresholds for therapies: highlights of the St Gallen International Expert Consensus on the Primary Therapy of Early Breast Cancer 2009

(2009) A. Goldhirsch et al.   ANNALS OF ONCOLOGY

Design, Synthesis, Characterization, and Biological Evaluation of Triazine Dendrimers Bearing Paclitaxel Using Ester and Ester/Disulfide Linkages

(2009) Jongdoo Lim et al.   BIOCONJUGATE CHEMISTRY

The use of PEGylated liposomes to prolong circulation lifetimes of tissue plasminogen activator

(2009) Ji-Young Kim et al.   BIOMATERIALS

Gene delivery targeted to the brain using an Angiopep-conjugated polyethyleneglycol-modified polyamidoamine dendrimer

(2009) Weilun Ke et al.   BIOMATERIALS

Targeted epidermal growth factor receptor nanoparticle bioconjugates for breast cancer therapy

(2009) Sarbari Acharya et al.   BIOMATERIALS

Drug permeability and mucoadhesion properties of thiolated trimethyl chitosan nanoparticles in oral insulin delivery

(2009) Lichen Yin et al.   BIOMATERIALS

Photoacoustic imaging of living mouse brain vasculature using hollow gold nanospheres

(2009) Wei Lu et al.   BIOMATERIALS

Nimotuzumab, an Antitumor Antibody that Targets the Epidermal Growth Factor Receptor, Blocks Ligand Binding while Permitting the Active Receptor Conformation

(2009) A. Talavera et al.   CANCER RESEARCH

Risk of Hand-Foot Skin Reaction with the Multitargeted Kinase Inhibitor Sunitinib in Patients with Renal Cell and Non–Renal Cell Carcinoma: A Meta-analysis

(2009) David Chu et al.   Clinical Genitourinary Cancer

Intravenous transferrin, RGD peptide and dual-targeted nanoparticles enhance anti-VEGF intraceptor gene delivery to laser-induced CNV

(2009) S R Singh et al.   GENE THERAPY

Preparation, characterization and drug release behavior of polyion complex micelles

(2009) Yali Luo et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

In VivoNano-imaging of Membrane Dynamics in Metastatic Tumor Cells Using Quantum Dots

(2009) Kohsuke Gonda et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Pegylated Liposomal Doxorubicin Plus Docetaxel Significantly Improves Time to Progression Without Additive Cardiotoxicity Compared With Docetaxel Monotherapy in Patients With Advanced Breast Cancer Previously Treated With Neoadjuvant-Adjuvant Anthracycline Therapy: Results From a Randomized Phase III Study

(2009) Joseph A. Sparano et al.   JOURNAL OF CLINICAL ONCOLOGY

Synthesis and evaluation of lauryl succinyl chitosan particles towards oral insulin delivery and absorption

(2009) M.R. Rekha et al.   JOURNAL OF CONTROLLED RELEASE

Tumor regression after systemic administration of a novel tumor-targeted gene delivery system carrying a therapeutic plasmid DNA

(2009) Swati Koppu et al.   JOURNAL OF CONTROLLED RELEASE

Negative Guidance Factor-Induced Macropinocytosis in the Growth Cone Plays a Critical Role in Repulsive Axon Turning

(2009) A. L. Kolpak et al.   JOURNAL OF NEUROSCIENCE

Nanoparticle-Mediated IgE−Receptor Aggregation and Signaling in RBL Mast Cells

(2009) Yu-Fen Huang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Sensitive and multiplexed detection of proteomic antigens via quantum dot aggregation

(2009) Chinmay Soman et al.   Nanomedicine-Nanotechnology Biology and Medicine

Gold nanoparticles induce cytotoxicity in the alveolar type-II cell lines A549 and NCIH441

(2009) Chiara Uboldi et al.   Particle and Fibre Toxicology

Molecular Magnetic Resonance Imaging Approaches Used to Aid in the Understanding of Angiogenesis In Vivo: Implications for Tissue Engineering

(2009) Rheal A. Towner et al.   TISSUE ENGINEERING PART A

DNA Vector Augments Inflammation in Epithelial Cells via EGFR-Dependent Regulation of TLR4 and TLR2

(2008) Kenneth Liu et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Sequential continuous infusion of fludarabine and cytarabine associated with liposomal daunorubicin (DaunoXome®) (FLAD) in primary refractory or relapsed adult acute myeloid leukemia patients

(2008) Andrea Camera et al.   ANNALS OF HEMATOLOGY

Antibody Targeting of Camptothecin-Loaded PLGA Nanoparticles to Tumor Cells

(2008) Paul A. McCarron et al.   BIOCONJUGATE CHEMISTRY

Click Chemistry Functionalized Polymeric Nanoparticles Target Corneal Epithelial Cells through RGD-Cell Surface Receptors

(2008) Jiao Lu et al.   BIOCONJUGATE CHEMISTRY

Environment-Responsive Block Copolymer Micelles with a Disulfide Cross-Linked Core for Enhanced siRNA Delivery

(2008) Satoru Matsumoto et al.   BIOMACROMOLECULES

Liposomal daunorubicinversusstandard daunorubicin: long term follow-up of the GIMEMA GSI 103 AMLE randomized trial in patients older than 60 years with acute myelogenous leukaemia

(2008) Roberto Latagliata et al.   BRITISH JOURNAL OF HAEMATOLOGY

Prostate-Specific Membrane Antigen Expression Is a Potential Prognostic Marker in Endometrial Adenocarcinoma

(2008) P. Mhawech-Fauceglia et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

HER2-targeted therapy in breast cancer. Monoclonal antibodies and tyrosine kinase inhibitors

(2008) Dorte Lisbet Nielsen et al.   CANCER TREATMENT REVIEWS

Current perspective – Trastuzumab

(2008) Peter S. Hall et al.   EUROPEAN JOURNAL OF CANCER

Specific and non-specific phagocytosis of ligand-grafted PLGA microspheres by macrophages

(2008) Nolwenn Brandhonneur et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Transferrin- and transferrin-receptor-antibody-modified nanoparticles enable drug delivery across the blood–brain barrier (BBB)

(2008) Karsten Ulbrich et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Fluorescent labeled anti-EGFR antibody for identification of regional and distant metastasis in a preclinical xenograft model

(2008) John P. Gleysteen et al.   HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK

Tumor-specific antibody-mediated targeted delivery of Doxil® reduces the manifestation of auricular erythema side effect in mice

(2008) Tamer A. Elbayoumi et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Targeting colon cancer cells using PEGylated liposomes modified with a fibronectin-mimetic peptide

(2008) Ashish Garg et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Enhanced surface attachment of protein-type targeting ligands to poly(lactide-co-glycolide) nanoparticles using variable expression of polymeric acid functionality

(2008) Paul A. McCarron et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Antitumor efficacy of cisplatin-loaded glycol chitosan nanoparticles in tumor-bearing mice

(2008) Jong-Ho Kim et al.   JOURNAL OF CONTROLLED RELEASE

New HPMA copolymer-based drug carriers with covalently bound hydrophobic substituents for solid tumour targeting

(2008) P. Chytil et al.   JOURNAL OF CONTROLLED RELEASE

Ultradeformable cationic liposomes for delivery of small interfering RNA (siRNA) into human primary melanocytes

(2008) B. Geusens et al.   JOURNAL OF CONTROLLED RELEASE

PEG-Detachable Polyplex Micelles Based on Disulfide-Linked Block Catiomers as Bioresponsive Nonviral Gene Vectors

(2008) Seiji Takae et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Complexes of Cationic Block Copolymer Micelles with DNA: Histone/DNA Complex Mimetics

(2008) Marina Talelli et al.   MACROMOLECULAR BIOSCIENCE

Factors Affecting the Clearance and Biodistribution of Polymeric Nanoparticles

(2008) Frank Alexis et al.   MOLECULAR PHARMACEUTICS

Selective Probing and Imaging of Cells with Single Walled Carbon Nanotubes as Near-Infrared Fluorescent Molecules

(2008) Kevin Welsher et al.   NANO LETTERS

Nanoparticle-mediated cellular response is size-dependent

(2008) Wen Jiang et al.   Nature Nanotechnology

Targeted delivery of cisplatin to prostate cancer cells by aptamer functionalized Pt(IV) prodrug-PLGA-PEG nanoparticles

(2008) S. Dhar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Potential of Liposomal Drug Delivery for the Treatment of Inflammatory Arthritis

(2008) Anne S. Vanniasinghe et al.   SEMINARS IN ARTHRITIS AND RHEUMATISM

Systems Biology of Growth Factor-Induced Receptor Endocytosis

(2008) Yaara Zwang et al.   TRAFFIC

Multifunctional poly(d,l-lactide-co-glycolide)/montmorillonite (PLGA/MMT) nanoparticles decorated by Trastuzumab for targeted chemotherapy of breast cancer

(2007) Bingfeng Sun et al.   BIOMATERIALS

Arg-Gly-Asp (RGD) peptide conjugated poly(lactic acid)-poly(ethylene oxide) micelle for targeted drug delivery

(2007) Zhiyuan Hu et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Cytotoxicity of Nanoparticles

(2007) Nastassja Lewinski et al.   Small