NLRP3 promotes inflammation-induced skin cancer but is dispensable for asbestos-induced mesothelioma

MexTAg mice exposed to asbestos develop cancer that faithfully replicates key features of the pathogenesis of human mesothelioma

(2010) Cleo Robinson et al.   EUROPEAN JOURNAL OF CANCER

The NLRP3 inflammasome functions as a negative regulator of tumorigenesis during colitis-associated cancer

(2010) Irving C. Allen et al.   JOURNAL OF EXPERIMENTAL MEDICINE

IL-18 Production Downstream of the Nlrp3 Inflammasome Confers Protection against Colorectal Tumor Formation

(2010) M. H. Zaki et al.   JOURNAL OF IMMUNOLOGY

Innate immune processes are sufficient for driving silicosis in mice

(2010) Celine A. Beamer et al.   JOURNAL OF LEUKOCYTE BIOLOGY

The Nalp3 inflammasome is essential for the development of silicosis

(2008) Suzanne L. Cassel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Demonstration of inflammation-induced cancer and cancer immunoediting during primary tumorigenesis

(2008) J. B. Swann et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IMMUNOLOGY: How Frustration Leads to Inflammation

(2008) L. A. J. O'Neill   SCIENCE

Innate Immune Activation Through Nalp3 Inflammasome Sensing of Asbestos and Silica

(2008) C. Dostert et al.   SCIENCE